Ornithorhynchus anatinus (platypus): 100085480
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Entry
100085480 CDS
T01045
Symbol
MAPK1
Name
(RefSeq) mitogen-activated protein kinase 1 isoform X1
KO
K04371
mitogen-activated protein kinase 1/3 [EC:
2.7.11.24
]
Organism
oaa
Ornithorhynchus anatinus (platypus)
Pathway
oaa01521
EGFR tyrosine kinase inhibitor resistance
oaa01522
Endocrine resistance
oaa01524
Platinum drug resistance
oaa04010
MAPK signaling pathway
oaa04012
ErbB signaling pathway
oaa04014
Ras signaling pathway
oaa04015
Rap1 signaling pathway
oaa04022
cGMP-PKG signaling pathway
oaa04024
cAMP signaling pathway
oaa04062
Chemokine signaling pathway
oaa04066
HIF-1 signaling pathway
oaa04068
FoxO signaling pathway
oaa04071
Sphingolipid signaling pathway
oaa04072
Phospholipase D signaling pathway
oaa04114
Oocyte meiosis
oaa04140
Autophagy - animal
oaa04148
Efferocytosis
oaa04150
mTOR signaling pathway
oaa04151
PI3K-Akt signaling pathway
oaa04210
Apoptosis
oaa04218
Cellular senescence
oaa04261
Adrenergic signaling in cardiomyocytes
oaa04270
Vascular smooth muscle contraction
oaa04350
TGF-beta signaling pathway
oaa04360
Axon guidance
oaa04370
VEGF signaling pathway
oaa04371
Apelin signaling pathway
oaa04380
Osteoclast differentiation
oaa04510
Focal adhesion
oaa04520
Adherens junction
oaa04540
Gap junction
oaa04550
Signaling pathways regulating pluripotency of stem cells
oaa04611
Platelet activation
oaa04613
Neutrophil extracellular trap formation
oaa04620
Toll-like receptor signaling pathway
oaa04621
NOD-like receptor signaling pathway
oaa04625
C-type lectin receptor signaling pathway
oaa04650
Natural killer cell mediated cytotoxicity
oaa04657
IL-17 signaling pathway
oaa04658
Th1 and Th2 cell differentiation
oaa04659
Th17 cell differentiation
oaa04660
T cell receptor signaling pathway
oaa04662
B cell receptor signaling pathway
oaa04664
Fc epsilon RI signaling pathway
oaa04666
Fc gamma R-mediated phagocytosis
oaa04668
TNF signaling pathway
oaa04713
Circadian entrainment
oaa04720
Long-term potentiation
oaa04722
Neurotrophin signaling pathway
oaa04723
Retrograde endocannabinoid signaling
oaa04724
Glutamatergic synapse
oaa04725
Cholinergic synapse
oaa04726
Serotonergic synapse
oaa04730
Long-term depression
oaa04810
Regulation of actin cytoskeleton
oaa04910
Insulin signaling pathway
oaa04912
GnRH signaling pathway
oaa04914
Progesterone-mediated oocyte maturation
oaa04915
Estrogen signaling pathway
oaa04916
Melanogenesis
oaa04917
Prolactin signaling pathway
oaa04919
Thyroid hormone signaling pathway
oaa04921
Oxytocin signaling pathway
oaa04926
Relaxin signaling pathway
oaa04928
Parathyroid hormone synthesis, secretion and action
oaa04929
GnRH secretion
oaa04930
Type II diabetes mellitus
oaa04933
AGE-RAGE signaling pathway in diabetic complications
oaa04934
Cushing syndrome
oaa04935
Growth hormone synthesis, secretion and action
oaa04960
Aldosterone-regulated sodium reabsorption
oaa05010
Alzheimer disease
oaa05020
Prion disease
oaa05022
Pathways of neurodegeneration - multiple diseases
oaa05034
Alcoholism
oaa05132
Salmonella infection
oaa05133
Pertussis
oaa05135
Yersinia infection
oaa05140
Leishmaniasis
oaa05142
Chagas disease
oaa05145
Toxoplasmosis
oaa05152
Tuberculosis
oaa05160
Hepatitis C
oaa05161
Hepatitis B
oaa05163
Human cytomegalovirus infection
oaa05164
Influenza A
oaa05165
Human papillomavirus infection
oaa05166
Human T-cell leukemia virus 1 infection
oaa05167
Kaposi sarcoma-associated herpesvirus infection
oaa05170
Human immunodeficiency virus 1 infection
oaa05171
Coronavirus disease - COVID-19
oaa05200
Pathways in cancer
oaa05203
Viral carcinogenesis
oaa05205
Proteoglycans in cancer
oaa05206
MicroRNAs in cancer
oaa05207
Chemical carcinogenesis - receptor activation
oaa05208
Chemical carcinogenesis - reactive oxygen species
oaa05210
Colorectal cancer
oaa05211
Renal cell carcinoma
oaa05212
Pancreatic cancer
oaa05213
Endometrial cancer
oaa05214
Glioma
oaa05215
Prostate cancer
oaa05216
Thyroid cancer
oaa05218
Melanoma
oaa05219
Bladder cancer
oaa05220
Chronic myeloid leukemia
oaa05221
Acute myeloid leukemia
oaa05223
Non-small cell lung cancer
oaa05224
Breast cancer
oaa05225
Hepatocellular carcinoma
oaa05226
Gastric cancer
oaa05230
Central carbon metabolism in cancer
oaa05231
Choline metabolism in cancer
oaa05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
oaa05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
oaa00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
100085480 (MAPK1)
04012 ErbB signaling pathway
100085480 (MAPK1)
04014 Ras signaling pathway
100085480 (MAPK1)
04015 Rap1 signaling pathway
100085480 (MAPK1)
04350 TGF-beta signaling pathway
100085480 (MAPK1)
04370 VEGF signaling pathway
100085480 (MAPK1)
04371 Apelin signaling pathway
100085480 (MAPK1)
04668 TNF signaling pathway
100085480 (MAPK1)
04066 HIF-1 signaling pathway
100085480 (MAPK1)
04068 FoxO signaling pathway
100085480 (MAPK1)
04072 Phospholipase D signaling pathway
100085480 (MAPK1)
04071 Sphingolipid signaling pathway
100085480 (MAPK1)
04024 cAMP signaling pathway
100085480 (MAPK1)
04022 cGMP-PKG signaling pathway
100085480 (MAPK1)
04151 PI3K-Akt signaling pathway
100085480 (MAPK1)
04150 mTOR signaling pathway
100085480 (MAPK1)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
100085480 (MAPK1)
04148 Efferocytosis
100085480 (MAPK1)
09143 Cell growth and death
04114 Oocyte meiosis
100085480 (MAPK1)
04210 Apoptosis
100085480 (MAPK1)
04218 Cellular senescence
100085480 (MAPK1)
09144 Cellular community - eukaryotes
04510 Focal adhesion
100085480 (MAPK1)
04520 Adherens junction
100085480 (MAPK1)
04540 Gap junction
100085480 (MAPK1)
04550 Signaling pathways regulating pluripotency of stem cells
100085480 (MAPK1)
09142 Cell motility
04810 Regulation of actin cytoskeleton
100085480 (MAPK1)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
100085480 (MAPK1)
04613 Neutrophil extracellular trap formation
100085480 (MAPK1)
04620 Toll-like receptor signaling pathway
100085480 (MAPK1)
04621 NOD-like receptor signaling pathway
100085480 (MAPK1)
04625 C-type lectin receptor signaling pathway
100085480 (MAPK1)
04650 Natural killer cell mediated cytotoxicity
100085480 (MAPK1)
04660 T cell receptor signaling pathway
100085480 (MAPK1)
04658 Th1 and Th2 cell differentiation
100085480 (MAPK1)
04659 Th17 cell differentiation
100085480 (MAPK1)
04657 IL-17 signaling pathway
100085480 (MAPK1)
04662 B cell receptor signaling pathway
100085480 (MAPK1)
04664 Fc epsilon RI signaling pathway
100085480 (MAPK1)
04666 Fc gamma R-mediated phagocytosis
100085480 (MAPK1)
04062 Chemokine signaling pathway
100085480 (MAPK1)
09152 Endocrine system
04910 Insulin signaling pathway
100085480 (MAPK1)
04929 GnRH secretion
100085480 (MAPK1)
04912 GnRH signaling pathway
100085480 (MAPK1)
04915 Estrogen signaling pathway
100085480 (MAPK1)
04914 Progesterone-mediated oocyte maturation
100085480 (MAPK1)
04917 Prolactin signaling pathway
100085480 (MAPK1)
04921 Oxytocin signaling pathway
100085480 (MAPK1)
04926 Relaxin signaling pathway
100085480 (MAPK1)
04935 Growth hormone synthesis, secretion and action
100085480 (MAPK1)
04919 Thyroid hormone signaling pathway
100085480 (MAPK1)
04928 Parathyroid hormone synthesis, secretion and action
100085480 (MAPK1)
04916 Melanogenesis
100085480 (MAPK1)
09153 Circulatory system
04261 Adrenergic signaling in cardiomyocytes
100085480 (MAPK1)
04270 Vascular smooth muscle contraction
100085480 (MAPK1)
09155 Excretory system
04960 Aldosterone-regulated sodium reabsorption
100085480 (MAPK1)
09156 Nervous system
04724 Glutamatergic synapse
100085480 (MAPK1)
04725 Cholinergic synapse
100085480 (MAPK1)
04726 Serotonergic synapse
100085480 (MAPK1)
04720 Long-term potentiation
100085480 (MAPK1)
04730 Long-term depression
100085480 (MAPK1)
04723 Retrograde endocannabinoid signaling
100085480 (MAPK1)
04722 Neurotrophin signaling pathway
100085480 (MAPK1)
09158 Development and regeneration
04360 Axon guidance
100085480 (MAPK1)
04380 Osteoclast differentiation
100085480 (MAPK1)
09159 Environmental adaptation
04713 Circadian entrainment
100085480 (MAPK1)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
100085480 (MAPK1)
05206 MicroRNAs in cancer
100085480 (MAPK1)
05205 Proteoglycans in cancer
100085480 (MAPK1)
05207 Chemical carcinogenesis - receptor activation
100085480 (MAPK1)
05208 Chemical carcinogenesis - reactive oxygen species
100085480 (MAPK1)
05203 Viral carcinogenesis
100085480 (MAPK1)
05230 Central carbon metabolism in cancer
100085480 (MAPK1)
05231 Choline metabolism in cancer
100085480 (MAPK1)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
100085480 (MAPK1)
09162 Cancer: specific types
05210 Colorectal cancer
100085480 (MAPK1)
05212 Pancreatic cancer
100085480 (MAPK1)
05225 Hepatocellular carcinoma
100085480 (MAPK1)
05226 Gastric cancer
100085480 (MAPK1)
05214 Glioma
100085480 (MAPK1)
05216 Thyroid cancer
100085480 (MAPK1)
05221 Acute myeloid leukemia
100085480 (MAPK1)
05220 Chronic myeloid leukemia
100085480 (MAPK1)
05218 Melanoma
100085480 (MAPK1)
05211 Renal cell carcinoma
100085480 (MAPK1)
05219 Bladder cancer
100085480 (MAPK1)
05215 Prostate cancer
100085480 (MAPK1)
05213 Endometrial cancer
100085480 (MAPK1)
05224 Breast cancer
100085480 (MAPK1)
05223 Non-small cell lung cancer
100085480 (MAPK1)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
100085480 (MAPK1)
05170 Human immunodeficiency virus 1 infection
100085480 (MAPK1)
05161 Hepatitis B
100085480 (MAPK1)
05160 Hepatitis C
100085480 (MAPK1)
05171 Coronavirus disease - COVID-19
100085480 (MAPK1)
05164 Influenza A
100085480 (MAPK1)
05163 Human cytomegalovirus infection
100085480 (MAPK1)
05167 Kaposi sarcoma-associated herpesvirus infection
100085480 (MAPK1)
05165 Human papillomavirus infection
100085480 (MAPK1)
09171 Infectious disease: bacterial
05132 Salmonella infection
100085480 (MAPK1)
05135 Yersinia infection
100085480 (MAPK1)
05133 Pertussis
100085480 (MAPK1)
05152 Tuberculosis
100085480 (MAPK1)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
100085480 (MAPK1)
05140 Leishmaniasis
100085480 (MAPK1)
05142 Chagas disease
100085480 (MAPK1)
09164 Neurodegenerative disease
05010 Alzheimer disease
100085480 (MAPK1)
05020 Prion disease
100085480 (MAPK1)
05022 Pathways of neurodegeneration - multiple diseases
100085480 (MAPK1)
09165 Substance dependence
05034 Alcoholism
100085480 (MAPK1)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
100085480 (MAPK1)
09167 Endocrine and metabolic disease
04930 Type II diabetes mellitus
100085480 (MAPK1)
04933 AGE-RAGE signaling pathway in diabetic complications
100085480 (MAPK1)
04934 Cushing syndrome
100085480 (MAPK1)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
100085480 (MAPK1)
01524 Platinum drug resistance
100085480 (MAPK1)
01522 Endocrine resistance
100085480 (MAPK1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
oaa01001
]
100085480 (MAPK1)
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
oaa03036
]
100085480 (MAPK1)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
oaa04147
]
100085480 (MAPK1)
Enzymes [BR:
oaa01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.24 mitogen-activated protein kinase
100085480 (MAPK1)
Protein kinases [BR:
oaa01001
]
Serine/threonine kinases: CMGC group
MAPK family [OT]
100085480 (MAPK1)
Chromosome and associated proteins [BR:
oaa03036
]
Eukaryotic type
Centromeric chromatin formation proteins
SAC (spindle assembly checkpoint) factors
Protein kinases
100085480 (MAPK1)
Exosome [BR:
oaa04147
]
Exosomal proteins
Exosomal proteins of haemopoietic cells (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
100085480 (MAPK1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
ABC1
APH
STATB_N
Haspin_kinase
FTA2
Kdo
Motif
Other DBs
NCBI-GeneID:
100085480
NCBI-ProteinID:
XP_028904884
Ensembl:
ENSOANG00000037598
UniProt:
A0A6I8N212
LinkDB
All DBs
Position
21:23395625..23433659
Genome browser
AA seq
362 aa
AA seq
DB search
MAAGAAGGGGGGPELVRGQLFDVGPRYTNLSYIGEGAYGMVCSAYDNVNKVRVAIKKISP
FEHQTYCQRTLREIKILLRFRHENIIGINDIIRAPTIEQMKDVYIVQDLMETDLYKLLKT
QHLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARVADPDH
DHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLN
HILGILGSPSQEDLNCIINLKARNYLLSLPHKNKVPWNRLFPNADPKALDLLDKMLTFNP
HKRIEVEQALAHPYLEQYYDPSDEPVAEAPFKFDMELDDLPKEKLKELIFEETARFQPGH
RS
NT seq
1089 nt
NT seq
+upstream
nt +downstream
nt
atggcggcgggggctgcggggggcgggggcggcgggccggagctggtccgcgggcagctc
ttcgacgtgggcccgcgctacaccaacctctcctacatcggcgagggcgcctacggcatg
gtctgctccgcctacgataacgtcaataaagttcgggtggccatcaagaagatcagcccc
ttcgagcaccagacgtattgccagagaactctgcgggagatcaagatcttactgcgcttc
cggcacgagaatatcatcggcatcaatgacatcatccgcgccccgaccatcgagcagatg
aaagatgtctacatcgtgcaggacctgatggagacggacctctacaagctcctgaagacg
cagcacctcagcaacgaccacatctgctatttcctctaccagatcctgaggggcctcaag
tacatccactccgccaacgtcctgcaccgggacctcaagccctccaacctgctgctcaac
accacgtgcgacctcaagatctgcgacttcgggctggcgcgggtcgccgacccggaccac
gaccacacgggcttcctgacggagtacgtggccacgcgctggtaccgggcccccgagatc
atgctcaactcgaagggttacaccaagtcgatcgacatctggtccgtgggctgcatcctg
gccgagatgctgtccaaccgacccatcttcccggggaagcactatctcgaccagctgaac
cacatcctcggcatcctcgggtccccgtcgcaggaagacctgaactgcatcatcaacctg
aaggccagaaattacctgctctcccttccccacaaaaacaaggtgccgtggaacaggctg
tttccgaacgccgatcccaaagctctggatctgctggataagatgctgaccttcaacccg
cacaagaggatcgaagtggagcaggcgctggcccacccctatctggagcagtattacgac
cccagcgatgagcctgtagccgaggccccgttcaagttcgacatggagctcgatgacctg
cccaaggagaagctgaaggagctcattttcgaggagacggcgcgattccagccgggacac
cgatcgtaa
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integrated database retrieval system