Ornithorhynchus anatinus (platypus): 100086661 Help Entry 100086661         CDS       T01045                                  Symbol TSC2 Name (RefSeq) tuberin isoform X1   KO K07207   tuberous sclerosis 2 Organism oaa  Ornithorhynchus anatinus (platypus) Pathway oaa04072   Phospholipase D signaling pathway oaa04115   p53 signaling pathway oaa04140   Autophagy - animal oaa04150   mTOR signaling pathway oaa04151   PI3K-Akt signaling pathway oaa04152   AMPK signaling pathway oaa04211   Longevity regulating pathway oaa04218   Cellular senescence oaa04714   Thermogenesis oaa04910   Insulin signaling pathway oaa04919   Thyroid hormone signaling pathway oaa05163   Human cytomegalovirus infection oaa05165   Human papillomavirus infection oaa05168   Herpes simplex virus 1 infection oaa05231   Choline metabolism in cancer Brite KEGG Orthology (KO) [BR:oaa00001]  09130 Environmental Information Processing   09132 Signal transduction    04072 Phospholipase D signaling pathway     100086661 (TSC2)    04151 PI3K-Akt signaling pathway     100086661 (TSC2)    04152 AMPK signaling pathway     100086661 (TSC2)    04150 mTOR signaling pathway     100086661 (TSC2)  09140 Cellular Processes   09141 Transport and catabolism    04140 Autophagy - animal     100086661 (TSC2)   09143 Cell growth and death    04115 p53 signaling pathway     100086661 (TSC2)    04218 Cellular senescence     100086661 (TSC2)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     100086661 (TSC2)    04919 Thyroid hormone signaling pathway     100086661 (TSC2)   09149 Aging    04211 Longevity regulating pathway     100086661 (TSC2)   09159 Environmental adaptation    04714 Thermogenesis     100086661 (TSC2)  09160 Human Diseases   09161 Cancer: overview    05231 Choline metabolism in cancer     100086661 (TSC2)   09172 Infectious disease: viral    05168 Herpes simplex virus 1 infection     100086661 (TSC2)    05163 Human cytomegalovirus infection     100086661 (TSC2)    05165 Human papillomavirus infection     100086661 (TSC2)  09180 Brite Hierarchies   09181 Protein families: metabolism    01009 Protein phosphatases and associated proteins [BR:oaa01009]     100086661 (TSC2) Protein phosphatases and associated proteins [BR:oaa01009]  Protein serine/threonine phosphatases   Phosphoprotein phosphatases (PPPs)    Protein phosphatase-1     PP1-interacting proteins (PIPs)      100086661 (TSC2) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Tuberin DUF3384 Rap_GAP Cnd1 Motif Other DBs NCBI-GeneID:  100086661 NCBI-ProteinID:  XP_028904728 Ensembl:  ENSOANG00000009994 LinkDB All DBs Position 21:16732185..16768123 Genome browser AA seq 1828 aa AA seqDB search MAKPPSKDSGFKEKFKTLLGLGTPRSSGRSSEGRQTEFIVTAEILRELSLECGLNNRIRA ISQICDVAKTKKFEEHAVEAIWKAVADMLQPEGPAEARHAVLHLLKAIVQGQGEHLGILR AHIFRVIKEYPSGEDLPERLEVFKALTDNGRYIAYLEEDLAEFVLQWMSVGLSSDFLLVL VNLVKFNSCYLDDHIAPMVHLICLLCIRTSSSVDIEVSLQVLDAVVCYNCLPSETLPAFI VTLCRTINVKELCEPCWKLMRNLLGTHLGHSAIYNMCRIMEDRAYMEDAPLLRGAVFFVG MALWGAHRLPSLRNSPMSVLPSFYKAMTCPNEVVSYEIVLSVTRLIKKYRAELQAVSWDV LLDILERLLQQLQSIESQELKSIVHDLLTTVEERCDQNDFHGSEERYFELIERCAHQRPE SSVLNLIAYRARAIHPAKDGWIQNLQLLMERFFRNEPRSAVRIKVLDVLSFVLSINRQFY EEELINSVVIPQLAHIPEDRDPQVRKLATQLLVDVAEGCHTHHFNSLLDVIEKVTARPLS PPLELEARDVPSFLASLEDVKTAVLGLLVILETKLYTLPASHATMVYELLLQHIQLHYQH GYSLPTASSIRLQAFDFLLLLRADSLHRLGLPSKDGAVRFSPYCLCDAPEPERISEKKAG GTLSPPTGSPGLSGAPPAIRVGYLPYSLLFSVLLQCLKQETDWKVLKLVLSKLPESLRYK VLIFTSPCSVDQLSSALCAMLSDRKTPERLRGTPDGFSRTDLHLAVVPVLTALISYHRYL DKAKQRELVYCLEHGLIYRCANQCVLALSVCSVEMPDVIIKALPVLIVKLTHISATATMA IPLLEFLSTLARLPHLYRNFAAEQYASVFAISLPYTNPSKFNQYIVCLAHHVIAMWFIRC RLPFRKDFVPFITKGLRSNVLLSFDDTPEKDSFRARSTSLNERPKSSLRIAKSVRPGLAN SPPVKEIRESPAANAFRCRSISVSEHAVHRVQTSMTSSSLGSADESSMGQADDSMKRLHL ELTEACLDMMARYVFSNFTAVPKRSPVGEFLLAGGRTKTWLVGNKLVTVTTSVGAGARSL LGLDTEIHGSPEPRPDPVLQVRQTKEAPAKLESQAAGQQVCRGSRDRVRSMSGGHALRAG AQDSPVSLAPGPQGQPTPTCPDKTPPPKEKAHLAACVPLLTQGWAEILVRSPTGITSWLM SLENPLSPFSSDINNMPLQELSNALMAAERFKEHRETALYKSLSVPSSGLATGTARPTPL QRSNTVASFSSMLLSSCQGKLHRSVSWAESAVVLEEGSQREVDLREPDSPSAFPQGLEDF EASCSPQALTQEKVAQQQGGYSRSSSTSSQEERSFRSEELAPGAIPVEKGIGLGAGRPAG MEEEAAAFQPLSKSSSSPELQTLQGPGAGPEAGKLSPEGRAKSRSGHLEGAGAGAGPWAG HRAEEEEEDGGGRGAGPSQLEAPAAAPGGSPSSPGGHRPRGYTISDSAPSRRGKRMEREA FKGRAAAANAEKVPGINPSFVFLQLYHSPFFGEEANKPLLLPNETYERSVQLLDQIPSYD THKIAVLYVGEGQSTNEIAILSNEHGSYRYTEFLAGLGKLIELKDCQPDKIYLGGLAVCG EDGQFTYCWHDDIMQAIFHIATLMPTKDLDKNRCDKKRHLGNDFVTIVYNDSGEDFKLGT IKGQFNFVHVLITPLDYQCNLVTLQCRKDMEGLVDTSVAKIVSDRNLPFVARQMALHANM ASQVHHSRSNPTDIYPSKWIARLRHIKRLRHRIREETQYPGPGFPLLPVHPPAHAKSPPP PAPDPAAPYQTGQRTRLISSVDDFTDFV NT seq 5487 nt NT seq  +upstreamnt  +downstreamnt atggccaagccacccagcaaggattcggggttcaaggagaagttcaagaccctgttgggc ctgggcaccccacgatccagcggcagatcgtcagagggcaggcagacggagtttatcgtc actgctgaaatcctgagggagctgagtctggaatgtggcctcaacaaccgcatacgggcc ataagtcagatctgcgacgtggccaagaccaagaaatttgaggagcacgcggtggaggcc atctggaaagccgtggctgacatgctgcagcccgaagggccggctgaggctcggcatgcc gtcctgcacctgctcaaggccatcgtccaggggcagggagagcacctgggcatcctccgg gcccacatcttccgggtcatcaaggaatacccctccggagaggacctgcctgagaggctg gaggtgttcaaggcgctcacggacaacggccgctacatcgcctatctggaggaagatcta gccgagtttgtcctgcagtggatgtcggtgggcctgtcctctgacttcctgctcgtgctc gtcaacctggtgaagttcaacagctgctacctggatgaccacatcgccccgatggtccac ctcatctgcctcctgtgcatccggacctcgtcctccgtggacatagaggtgtccctgcag gtgctggatgccgtggtgtgttacaactgcctcccctccgagaccctgccggccttcatc gtcaccctctgccgcaccatcaacgtcaaggagctgtgtgagccctgctggaagcttatg cgcaacctactgggcacccacctggggcacagcgccatctataacatgtgccgcatcatg gaggacagggcctacatggaagacgcccccctgctgcgtggcgccgtgttcttcgtgggc atggcgctctggggtgcccaccggctgccctctctcaggaactcccccatgtccgtgctg ccctccttctacaaggctatgacgtgccccaacgaggtggtgtcctacgagatcgtcttg tcggtgaccaggctcatcaagaagtaccgcgcggagctccaggcggtcagctgggatgtc ctgttggacatcttggagcgtctgctgcagcagctgcagagcatcgagagccaagagctg aagtcgatcgtccacgacctgctgacgacggtggaggagcgctgtgaccagaacgacttc cacggttcggaggagcgctacttcgaactcatcgagcgatgcgcccatcagagacccgag tcgtccgtcctgaacctgatcgcctaccgcgcccgcgccatccaccccgccaaggacggc tggatccagaacctgcagctgctcatggagaggttcttcaggaacgaaccgcgcagcgca gtgcgcatcaaggtcttagacgtactgtcgtttgtgctcagcatcaacaggcagttctac gaggaggagctgatcaactcagtggtcatcccccagctggcccacatccccgaggacagg gacccgcaggtccggaagctggccacccagctgctggtagacgtggccgagggctgccac acacaccacttcaacagcctgctggacgtcatcgagaaggtcaccgcccgcccgttgtcc cctcctctggagctggaggcccgggacgtcccctccttcctggcttccctggaggacgta aagacggccgtcctgggcctgctggtcatcctcgagaccaagctgtacacgctgccggcc agccacgccaccatggtctatgagctgctgctgcagcacatccagctccactaccagcac ggctactctctgcccacggccagcagcatccgcctacaggcctttgacttcctgctgctg ctgcgggccgactcgttgcaccggctggggctgcccagcaaggacggagccgtccgcttc agcccctactgcctctgtgacgccccggagcccgagcgtatctcggagaagaaggccgga ggcaccctgtccccgcccaccggtagtcccggcctctcgggtgcgccgcctgctatccgt gtgggctacctgccctactccctgctcttcagcgtcctgctgcagtgcctcaagcaagag acggactggaaggttctcaagctggtgctcagcaagctccccgagtctctgcgctacaaa gtgctcatcttcacctccccgtgcagcgtcgaccagctgtcctccgctctctgtgccatg ctgtcagaccggaagacccccgaacgcctccgcgggaccccggatggcttctcccgcacc gacctgcacctggcggtggtgcctgtcctgacggcgctcatctcctaccaccgctacctc gataaggccaagcagcgggagctggtttactgcctggagcacggcctcatctaccgctgc gccaaccagtgcgtgctggccctgtccgtctgcagcgtcgagatgccagacgtcatcatc aaggccctgcctgtgctcatcgtcaagctgacccacatctccgccaccgccaccatggcc atccccctcctggaattcctgtccactctggccaggctgccgcatctctacaggaacttc gccgctgagcagtacgccagcgtctttgccatctccctgccctacaccaacccatccaag tttaaccagtacatcgtgtgcctggcccaccacgtcatcgccatgtggttcattcgctgc cgcctccccttccgcaaagactttgtccccttcatcaccaagggcctgcgttccaacgtg ctgctctcctttgacgacaccccagagaaggacagcttccgagcccggagcaccagcctc aacgagagacccaagagtagtttgaggatagccaaaagcgtaagaccaggcctggctaac tcccctcctgtgaaggaaatccgagagagcccagcggccaacgccttcaggtgccgcagc atcagcgtgtctgaacacgccgtgcacagggtccagacgtccatgaccagctcgagcctg gggtccgcggacgagagctcaatgggtcaggcggacgacagcatgaagaggctgcacctg gagctcacggaggcctgcctggacatgatggcccgctacgtcttctccaacttcaccgcc gtccccaagaggtctccggtcggggagtttctgctggccggtggccgcaccaagacctgg ctagtgggcaacaagctggtgacggtgacgaccagtgtgggggccggagcccgctctctg ctgggcctggacaccgagatccacggcagccccgagcccaggccggatcccgtcctgcaa gtgaggcagacgaaggaggcaccggccaagctggagtcccaggccgccggccagcaggtc tgcaggggctcccgggaccgagtccgctccatgtcaggaggtcacgctctgcgggctggg gcgcaggacagcccggtgtccttggccccgggaccccaggggcagcccactcccacctgc ccggacaagacccccccgccgaaggagaaagcccacctggctgcatgtgtgcccctgctg acccagggctgggctgagatcctggtccgcagcccgacagggatcaccagctggttgatg agcctggagaacccgctgagccccttctcttcggacatcaacaacatgccactgcaggag ttgtccaatgccctcatggcggccgagcgcttcaaggagcaccgggagaccgccctctac aagtccctgtccgtgccctcgtccggcctggccaccggcaccgccaggcccacgccactg cagcgctccaacaccgtggcctctttctcttctatgttgctgtccagttgtcaaggcaag ttgcacaggagtgtttcctgggcagagtctgcggtggtcctggaggaggggagccagcgg gaggtggacctgcgggagccggactcgcccagcgccttcccccaggggttagaagacttc gaggcgtcttgctcgcctcaggccctgacgcaagagaaggtcgcccagcaacagggaggc tacagccggtcctcctcgacatccagccaagaggagaggtcgttccgctcggaggagctg gcacccggcgccatccctgtggagaaggggatcgggctgggggcgggccggccggcaggg atggaggaggaggcggcggccttccagccgctgagcaagtccagctcctcgcccgagctg cagacgctgcaaggtcccggagctggccccgaggccgggaagctcagcccggaaggcagg gccaagtcgcgctccgggcacctggaaggggccggagctggggccgggccctgggcgggc catcgggcggaggaggaggaagaggatgggggcggtcggggggcagggccgagccagctg gaggcccctgcggccgcccccgggggctcccccagctccccgggcggccaccggccccgt ggctacaccatctcggactcggccccctcacggaggggcaagaggatggagagggaggcc ttcaagggccgggcggccgctgccaacgcggagaaggtgccgggcatcaacccgagcttc gtgttcctgcagctgtatcactccccattctttggcgaagaggccaacaagccgctcctg ctgcccaatgagacgtacgaacggtccgtccagctcctggatcagatcccgtcgtacgac acccacaagatcgccgtcctctacgtgggagagggtcagagcaccaacgagatcgccatc ctgtccaacgagcacggctcctaccgctacacggaattcctggcggggctgggcaagctg atcgagctcaaggactgccaaccggacaagatctacttgggcgggctggcggtgtgcgga gaggacggacagttcacctactgctggcacgacgacatcatgcaggccatcttccacatc gccacgttgatgcccaccaaggacctggacaaaaaccgctgtgataagaagcggcacctg ggcaacgactttgtgaccatcgtctacaatgactcgggggaggatttcaagctgggcacc atcaagggccagttcaacttcgtccacgtcctcatcacccccctcgactaccagtgcaac ctggtgacgctgcagtgccggaaagatatggaaggactcgtggacaccagcgtggccaag atcgtctcggaccggaacctgcctttcgtcgcccgccagatggcattgcatgccaatatg gcgtcccaggtccaccacagtcgctccaaccccaccgacatctacccctccaagtggatt gccaggctgcgccacatcaagagactccggcaccggatccgagaggagacgcagtacccc gggcccggcttccccctgctgccggtccacccgccggctcacgccaagtccccgcccccg ccggccccggaccccgccgccccctaccagacgggccagaggacgcggctcatctcctcc gtggacgacttcactgactttgtgtga

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