KEGG   Ornithorhynchus anatinus (platypus): 100088079
Entry
100088079         CDS       T01045                                 
Symbol
PRKACA
Name
(RefSeq) cAMP-dependent protein kinase catalytic subunit alpha isoform X1
  KO
K04345  protein kinase A [EC:2.7.11.11]
Organism
oaa  Ornithorhynchus anatinus (platypus)
Pathway
oaa01522  Endocrine resistance
oaa04010  MAPK signaling pathway
oaa04014  Ras signaling pathway
oaa04020  Calcium signaling pathway
oaa04024  cAMP signaling pathway
oaa04062  Chemokine signaling pathway
oaa04081  Hormone signaling
oaa04082  Neuroactive ligand signaling
oaa04114  Oocyte meiosis
oaa04140  Autophagy - animal
oaa04211  Longevity regulating pathway
oaa04213  Longevity regulating pathway - multiple species
oaa04261  Adrenergic signaling in cardiomyocytes
oaa04270  Vascular smooth muscle contraction
oaa04310  Wnt signaling pathway
oaa04340  Hedgehog signaling pathway
oaa04371  Apelin signaling pathway
oaa04530  Tight junction
oaa04540  Gap junction
oaa04611  Platelet activation
oaa04713  Circadian entrainment
oaa04714  Thermogenesis
oaa04720  Long-term potentiation
oaa04723  Retrograde endocannabinoid signaling
oaa04724  Glutamatergic synapse
oaa04725  Cholinergic synapse
oaa04726  Serotonergic synapse
oaa04727  GABAergic synapse
oaa04728  Dopaminergic synapse
oaa04740  Olfactory transduction
oaa04742  Taste transduction
oaa04750  Inflammatory mediator regulation of TRP channels
oaa04910  Insulin signaling pathway
oaa04911  Insulin secretion
oaa04912  GnRH signaling pathway
oaa04913  Ovarian steroidogenesis
oaa04914  Progesterone-mediated oocyte maturation
oaa04915  Estrogen signaling pathway
oaa04916  Melanogenesis
oaa04918  Thyroid hormone synthesis
oaa04919  Thyroid hormone signaling pathway
oaa04921  Oxytocin signaling pathway
oaa04922  Glucagon signaling pathway
oaa04923  Regulation of lipolysis in adipocytes
oaa04924  Renin secretion
oaa04925  Aldosterone synthesis and secretion
oaa04926  Relaxin signaling pathway
oaa04927  Cortisol synthesis and secretion
oaa04928  Parathyroid hormone synthesis, secretion and action
oaa04934  Cushing syndrome
oaa04935  Growth hormone synthesis, secretion and action
oaa04961  Endocrine and other factor-regulated calcium reabsorption
oaa04962  Vasopressin-regulated water reabsorption
oaa04970  Salivary secretion
oaa04971  Gastric acid secretion
oaa04976  Bile secretion
oaa05012  Parkinson disease
oaa05020  Prion disease
oaa05030  Cocaine addiction
oaa05031  Amphetamine addiction
oaa05032  Morphine addiction
oaa05034  Alcoholism
oaa05146  Amoebiasis
oaa05163  Human cytomegalovirus infection
oaa05165  Human papillomavirus infection
oaa05166  Human T-cell leukemia virus 1 infection
oaa05200  Pathways in cancer
oaa05203  Viral carcinogenesis
oaa05205  Proteoglycans in cancer
oaa05207  Chemical carcinogenesis - receptor activation
oaa05414  Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:oaa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    100088079 (PRKACA)
   04014 Ras signaling pathway
    100088079 (PRKACA)
   04310 Wnt signaling pathway
    100088079 (PRKACA)
   04340 Hedgehog signaling pathway
    100088079 (PRKACA)
   04371 Apelin signaling pathway
    100088079 (PRKACA)
   04020 Calcium signaling pathway
    100088079 (PRKACA)
   04024 cAMP signaling pathway
    100088079 (PRKACA)
  09133 Signaling molecules and interaction
   04082 Neuroactive ligand signaling
    100088079 (PRKACA)
   04081 Hormone signaling
    100088079 (PRKACA)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    100088079 (PRKACA)
  09143 Cell growth and death
   04114 Oocyte meiosis
    100088079 (PRKACA)
  09144 Cellular community - eukaryotes
   04530 Tight junction
    100088079 (PRKACA)
   04540 Gap junction
    100088079 (PRKACA)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    100088079 (PRKACA)
   04062 Chemokine signaling pathway
    100088079 (PRKACA)
  09152 Endocrine system
   04911 Insulin secretion
    100088079 (PRKACA)
   04910 Insulin signaling pathway
    100088079 (PRKACA)
   04922 Glucagon signaling pathway
    100088079 (PRKACA)
   04923 Regulation of lipolysis in adipocytes
    100088079 (PRKACA)
   04912 GnRH signaling pathway
    100088079 (PRKACA)
   04913 Ovarian steroidogenesis
    100088079 (PRKACA)
   04915 Estrogen signaling pathway
    100088079 (PRKACA)
   04914 Progesterone-mediated oocyte maturation
    100088079 (PRKACA)
   04921 Oxytocin signaling pathway
    100088079 (PRKACA)
   04926 Relaxin signaling pathway
    100088079 (PRKACA)
   04935 Growth hormone synthesis, secretion and action
    100088079 (PRKACA)
   04918 Thyroid hormone synthesis
    100088079 (PRKACA)
   04919 Thyroid hormone signaling pathway
    100088079 (PRKACA)
   04928 Parathyroid hormone synthesis, secretion and action
    100088079 (PRKACA)
   04916 Melanogenesis
    100088079 (PRKACA)
   04924 Renin secretion
    100088079 (PRKACA)
   04925 Aldosterone synthesis and secretion
    100088079 (PRKACA)
   04927 Cortisol synthesis and secretion
    100088079 (PRKACA)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    100088079 (PRKACA)
   04270 Vascular smooth muscle contraction
    100088079 (PRKACA)
  09154 Digestive system
   04970 Salivary secretion
    100088079 (PRKACA)
   04971 Gastric acid secretion
    100088079 (PRKACA)
   04976 Bile secretion
    100088079 (PRKACA)
  09155 Excretory system
   04962 Vasopressin-regulated water reabsorption
    100088079 (PRKACA)
   04961 Endocrine and other factor-regulated calcium reabsorption
    100088079 (PRKACA)
  09156 Nervous system
   04724 Glutamatergic synapse
    100088079 (PRKACA)
   04727 GABAergic synapse
    100088079 (PRKACA)
   04725 Cholinergic synapse
    100088079 (PRKACA)
   04728 Dopaminergic synapse
    100088079 (PRKACA)
   04726 Serotonergic synapse
    100088079 (PRKACA)
   04720 Long-term potentiation
    100088079 (PRKACA)
   04723 Retrograde endocannabinoid signaling
    100088079 (PRKACA)
  09157 Sensory system
   04740 Olfactory transduction
    100088079 (PRKACA)
   04742 Taste transduction
    100088079 (PRKACA)
   04750 Inflammatory mediator regulation of TRP channels
    100088079 (PRKACA)
  09149 Aging
   04211 Longevity regulating pathway
    100088079 (PRKACA)
   04213 Longevity regulating pathway - multiple species
    100088079 (PRKACA)
  09159 Environmental adaptation
   04713 Circadian entrainment
    100088079 (PRKACA)
   04714 Thermogenesis
    100088079 (PRKACA)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100088079 (PRKACA)
   05205 Proteoglycans in cancer
    100088079 (PRKACA)
   05207 Chemical carcinogenesis - receptor activation
    100088079 (PRKACA)
   05203 Viral carcinogenesis
    100088079 (PRKACA)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    100088079 (PRKACA)
   05163 Human cytomegalovirus infection
    100088079 (PRKACA)
   05165 Human papillomavirus infection
    100088079 (PRKACA)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    100088079 (PRKACA)
  09164 Neurodegenerative disease
   05012 Parkinson disease
    100088079 (PRKACA)
   05020 Prion disease
    100088079 (PRKACA)
  09165 Substance dependence
   05030 Cocaine addiction
    100088079 (PRKACA)
   05031 Amphetamine addiction
    100088079 (PRKACA)
   05032 Morphine addiction
    100088079 (PRKACA)
   05034 Alcoholism
    100088079 (PRKACA)
  09166 Cardiovascular disease
   05414 Dilated cardiomyopathy
    100088079 (PRKACA)
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    100088079 (PRKACA)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    100088079 (PRKACA)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:oaa01001]
    100088079 (PRKACA)
  09182 Protein families: genetic information processing
   03019 Messenger RNA biogenesis [BR:oaa03019]
    100088079 (PRKACA)
   03036 Chromosome and associated proteins [BR:oaa03036]
    100088079 (PRKACA)
Enzymes [BR:oaa01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.11  cAMP-dependent protein kinase
     100088079 (PRKACA)
Protein kinases [BR:oaa01001]
 Serine/threonine kinases: AGC group
  PKA family
   100088079 (PRKACA)
Messenger RNA biogenesis [BR:oaa03019]
 Eukaryotic type
  mRNA surveillance and transport factors
   mRNA cycle factors
    Common to processing body (P body) and stress granule
     100088079 (PRKACA)
Chromosome and associated proteins [BR:oaa03036]
 Eukaryotic type
  Centrosome formation proteins
   Kinases and associated factors
    100088079 (PRKACA)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Kinase-like ABC1 Pkinase_C
Other DBs
NCBI-GeneID: 100088079
NCBI-ProteinID: XP_028924707
Ensembl: ENSOANG00000006300
UniProt: F6URA9
LinkDB
Position
7:60211697..60245766
AA seq 351 aa
MGNAATTKKGSEIESVKEFLAKAKEDFLRKWENPSQNTAHLDQFERIKTLGTGSFGRVML
VKHKETGNHFAMKILDKQKVVKLKQIEHTLNEKRILQAVHFPFLVCLEYSFKDNSNLYMV
MEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGY
IEVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMVAGYPPFF
ADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRYGNLKNGVSDIKNHKWFVT
TDWIAIYQRKVEAPFIPKCKGPGDTSNFDDYEEEEIRVSISEKCAKEFADF
NT seq 1056 nt   +upstreamnt  +downstreamnt
atgggcaacgcggccaccaccaagaagggcagcgagattgagagcgtgaaagagtttcta
gccaaagccaaagaagacttccttcggaaatgggaaaatccatctcagaacacggcccat
ttggatcagtttgaacgtatcaagaccctggggacaggctcgtttgggcgggtgatgtta
gtgaagcacaaggagacggggaaccactttgccatgaaaatcctcgataaacagaaggtg
gtgaagctcaaacagattgaacacaccctgaatgagaagcgcatcctacaggctgttcac
tttccattccttgtctgtctagagtattccttcaaggacaactcaaacctgtacatggtg
atggagtacgtcccgggtggagagatgttctcccaccttcgccggattggacggttcagt
gagccacacgcccgcttctacgcggcccagatcgtcctgacttttgagtacctgcactcg
ctggacctcatctaccgggacctgaagcctgagaatctcctcattgaccagcagggctat
atcgaggtgacggactttggttttgccaaacgtgtgaaaggccgaacctggaccctctgt
ggtaccccagagtacctggcccctgagatcatcctgagcaagggttacaataaagctgtg
gactggtgggccctgggggtcctgatctatgagatggtcgctggctatccccccttcttt
gccgaccagcctatccagatctatgagaagattgtctccgggaaggtgcggttcccctcc
cacttcagctcggacttgaaggacctcctccggaacctgctccaggtggatctcaccaag
cgctatgggaacctcaagaacggtgtcagcgacatcaaaaaccacaagtggttcgtcacc
actgattggattgccatttaccagaggaaggtggaagctccatttataccaaagtgcaaa
ggaccaggcgatacaagcaacttcgatgactacgaggaggaggagatccgggtctccatt
tctgagaaatgcgccaaggagtttgccgacttctag

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