Ornithorhynchus anatinus (platypus): 100088450
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Entry
100088450 CDS
T01045
Symbol
PLA2G4E
Name
(RefSeq) cytosolic phospholipase A2 epsilon
KO
K16342
cytosolic phospholipase A2 [EC:
3.1.1.4
]
Organism
oaa
Ornithorhynchus anatinus (platypus)
Pathway
oaa00564
Glycerophospholipid metabolism
oaa00565
Ether lipid metabolism
oaa00590
Arachidonic acid metabolism
oaa00591
Linoleic acid metabolism
oaa00592
alpha-Linolenic acid metabolism
oaa01100
Metabolic pathways
oaa04010
MAPK signaling pathway
oaa04014
Ras signaling pathway
oaa04072
Phospholipase D signaling pathway
oaa04217
Necroptosis
oaa04270
Vascular smooth muscle contraction
oaa04370
VEGF signaling pathway
oaa04611
Platelet activation
oaa04664
Fc epsilon RI signaling pathway
oaa04666
Fc gamma R-mediated phagocytosis
oaa04724
Glutamatergic synapse
oaa04726
Serotonergic synapse
oaa04730
Long-term depression
oaa04750
Inflammatory mediator regulation of TRP channels
oaa04912
GnRH signaling pathway
oaa04913
Ovarian steroidogenesis
oaa04921
Oxytocin signaling pathway
oaa05231
Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
oaa00001
]
09100 Metabolism
09103 Lipid metabolism
00564 Glycerophospholipid metabolism
100088450 (PLA2G4E)
00565 Ether lipid metabolism
100088450 (PLA2G4E)
00590 Arachidonic acid metabolism
100088450 (PLA2G4E)
00591 Linoleic acid metabolism
100088450 (PLA2G4E)
00592 alpha-Linolenic acid metabolism
100088450 (PLA2G4E)
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
100088450 (PLA2G4E)
04014 Ras signaling pathway
100088450 (PLA2G4E)
04370 VEGF signaling pathway
100088450 (PLA2G4E)
04072 Phospholipase D signaling pathway
100088450 (PLA2G4E)
09140 Cellular Processes
09143 Cell growth and death
04217 Necroptosis
100088450 (PLA2G4E)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
100088450 (PLA2G4E)
04664 Fc epsilon RI signaling pathway
100088450 (PLA2G4E)
04666 Fc gamma R-mediated phagocytosis
100088450 (PLA2G4E)
09152 Endocrine system
04912 GnRH signaling pathway
100088450 (PLA2G4E)
04913 Ovarian steroidogenesis
100088450 (PLA2G4E)
04921 Oxytocin signaling pathway
100088450 (PLA2G4E)
09153 Circulatory system
04270 Vascular smooth muscle contraction
100088450 (PLA2G4E)
09156 Nervous system
04724 Glutamatergic synapse
100088450 (PLA2G4E)
04726 Serotonergic synapse
100088450 (PLA2G4E)
04730 Long-term depression
100088450 (PLA2G4E)
09157 Sensory system
04750 Inflammatory mediator regulation of TRP channels
100088450 (PLA2G4E)
09160 Human Diseases
09161 Cancer: overview
05231 Choline metabolism in cancer
100088450 (PLA2G4E)
Enzymes [BR:
oaa01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.1 Carboxylic-ester hydrolases
3.1.1.4 phospholipase A2
100088450 (PLA2G4E)
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Gene cluster
GFIT
Motif
Pfam:
PLA2_B
cPLA2_C2
C2
Motif
Other DBs
NCBI-GeneID:
100088450
NCBI-ProteinID:
XP_028933197
LinkDB
All DBs
Position
13:39692905..39718254
Genome browser
AA seq
843 aa
AA seq
DB search
MFQRQVPGWVSHFPSESRGGEAEDAEDAVTCGPQESSSPCHLLSVTIIRMRNVRQADVVS
QTDCFVTVWLPTASHEKRRTRTISNSSNPEWNETFRFQIQTRVKNVLELSVCDEDVLTPD
DHLLTVLYDLTKLCFRKKTHIKFPLNPEGMEDLEVEFLLEESPGPPERLLTNGVLVSRQL
SCLEVRANPGRQRRRHKRKVLTVTVDESYEQTRCMSSHVDPRCPRPDPTVFHYAKYLQPH
VTVKAPRSLQSSWMCCSGDRGRDDSSCMSLDRLQDGQEEAITVNKNCDLQMKSRDCSREL
DVRLGFSLCAEEQQFLLKRRPVAARALKQLLQLEEDLHEDEVPLVAIMATGGGTRSMTSM
YGHLLGLQKLGILDTASYITGLSGATWTMANLYKDANWSSKNLEGAIQEVRRHVVKNKLP
ALTPDQLCFYREELRQRAQEGYRVTFTDLWGLLLEAFLGDEKDDCKLSSQREALCRGQNP
LPIYLTINVKDNVSNQDFREWCEFTPFEVGLQKYGAFVRTEDFGSEFFMGRLMKRNPESR
ICYMLGLWSSIFSLNLLDAWNLSHTSEEFFHRWTRDRIYDIEDEPLLPEVPKCETNVLET
TVVTPGSWLSNTLRDTLTHRPLVSEFHNFIRGLQPHTDYLQHGQFSKWKDTTLDCFPNRL
TQSVNHLCLLDTAFFVNSSYPPLLRPERRVDVILHLNYCAGSQVKPLRQTCEYCSIQNIP
FPAYQLEGEDENNLKECYLINDSATPDAPVVIFFPLINSSFQKYKAPGVERSPDELEEGH
VNIYGHATPYATKELTYTESAFDRLVNLSEYNILNNQDTIIQALRLGVEKKKRCKSQSPS
QEP
NT seq
2532 nt
NT seq
+upstream
nt +downstream
nt
atgtttcagaggcaggtacctggctgggtgtcccacttcccaagcgagtcacgcggagga
gaggcggaggatgcagaggacgccgtcacctgtggcccccaggagagttcatctccctgc
cacttgctgtcggtgacgataatccggatgaggaacgtgcgccaggctgacgtggtgagc
cagaccgactgcttcgtgactgtctggctgccaacagcctcccacgagaagcgccgcact
aggaccatctccaactcgtcgaatcccgagtggaacgagaccttccgcttccagatccag
acccgggtgaagaacgtgctggagctgagcgtctgcgacgaggatgtgctgactccggac
gaccacctcttgaccgtcctctatgacctcaccaagctctgcttccggaagaaaacccac
atcaagttccccctcaaccccgagggcatggaagacctggaggtggagttcctactggag
gagagccccggccctcccgaacggctcctcaccaatggcgtgcttgtgtctcgccagttg
tcctgcctggaggtccgtgccaatcctgggaggcagaggaggagacacaaaaggaaagtg
ctcactgtgacagtggacgagtcctacgagcagacccgctgcatgtcatcccacgtggat
ccccgctgcccacgcccggaccccaccgtcttccactacgccaagtacctgcagccccac
gtgaccgtcaaagcgcccaggagcctccagtcctcctggatgtgctgcagtggtgaccgg
gggagagacgattcttcctgcatgtctctggaccgcctccaggatgggcaggaggaggca
attactgtgaacaagaactgtgacttacaaatgaagtcaagagactgctcccgggaactg
gatgtgcgcctgggcttcagcctctgtgcagaggagcagcagttcctgctgaagcggcgg
cccgtagcggctcgagccctcaagcagctgctccagctggaggaagatctgcacgaagat
gaggtgccactggtggccatcatggcgacggggggtgggaccaggtcgatgacctccatg
tacggccatttgctggggctgcagaagctgggcatcttggatacggccagctacatcacc
ggcctgtctggggccacttggaccatggccaacttgtacaaagacgccaactggtccagc
aagaacctagagggggccatccaggaggttcggaggcacgtggtcaaaaacaagctgccc
gccctgaccccggaccagctgtgcttctacagggaggagctgcgccagcgggcccaggag
ggctaccgggtcaccttcactgacctgtgggggctgctccttgaggccttcctgggggat
gagaaagacgactgcaagctgtccagccagagggaggctctgtgtcggggccagaacccc
ctccccatctacctcaccattaacgtcaaggacaatgtgagcaaccaagatttcagagag
tggtgcgagttcacgcccttcgaggtggggctgcagaaatacggcgccttcgtccgcacc
gaggacttcggctctgagttcttcatggggcggctgatgaagaggaacccggagtcgcgg
atatgctacatgctaggtctgtggagcagcatcttttccctgaacctcctggacgcctgg
aacctatcccacacctccgaggagttcttccacaggtggacacgcgacagaatctatgac
atcgaggacgagcccctgctgccagaggtccccaagtgcgagaccaacgtgctggagacg
acggtggtgaccccgggctcctggctgtccaacaccctgcgggataccctcactcaccgc
cccttggtgtccgagttccacaacttcatccggggcctgcagccgcacacagactacctc
caacacggccagttctccaagtggaaagacaccacgctggactgcttccccaaccggctg
acccagtcggtgaaccatttgtgcctgctggacaccgccttcttcgtcaactccagctac
cctcccctcctgaggccggagaggagagtcgacgtcatcctccacctcaactactgcgcc
ggctcccaggtcaagcccctgaggcagacctgcgagtactgcagtatccagaatatcccg
ttccccgcgtaccagctggaaggcgaagatgaaaataacctgaaggagtgctacctgata
aacgattctgctaccccagatgccccggtcgtgattttcttcccgctcatcaacagttcc
ttccagaagtacaaggctcccggggtggagcggagccccgatgagctggaggagggccac
gtcaatatctacggccacgccaccccgtacgccaccaaggagctgacgtacaccgagtcc
gcctttgatcgcttggtgaatctctcggagtacaacatcctgaacaaccaggacacgatc
atccaggccttgcgcttgggcgtggagaagaagaagcgttgtaagagccagagtccttcc
caagagccatga
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