Ornithorhynchus anatinus (platypus): 100090398
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Entry
100090398 CDS
T01045
Symbol
PDE3A
Name
(RefSeq) cGMP-inhibited 3',5'-cyclic phosphodiesterase A isoform X1
KO
K19021
cGMP-inhibited 3',5'-cyclic phosphodiesterase A [EC:
3.1.4.17
]
Organism
oaa
Ornithorhynchus anatinus (platypus)
Pathway
oaa00230
Purine metabolism
oaa01100
Metabolic pathways
oaa04022
cGMP-PKG signaling pathway
oaa04024
cAMP signaling pathway
oaa04924
Renin secretion
oaa05032
Morphine addiction
Brite
KEGG Orthology (KO) [BR:
oaa00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
100090398 (PDE3A)
09130 Environmental Information Processing
09132 Signal transduction
04024 cAMP signaling pathway
100090398 (PDE3A)
04022 cGMP-PKG signaling pathway
100090398 (PDE3A)
09150 Organismal Systems
09152 Endocrine system
04924 Renin secretion
100090398 (PDE3A)
09160 Human Diseases
09165 Substance dependence
05032 Morphine addiction
100090398 (PDE3A)
Enzymes [BR:
oaa01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.17 3',5'-cyclic-nucleotide phosphodiesterase
100090398 (PDE3A)
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GFIT
Motif
Pfam:
PDEase_I
DUF6171
Motif
Other DBs
NCBI-GeneID:
100090398
NCBI-ProteinID:
XP_028908211
Ensembl:
ENSOANG00000032057
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All DBs
Position
2:169328258..169627051
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AA seq
878 aa
AA seq
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MKGEGFRDTQADSGGQISVRIGVRHILKQSTFHQLYPPKLTGHPEWEHRRGPRGSQGSGT
SVPVDIAVMGEAHGLITDLLADPSLPPNVCTALRTVSNLLSAQLTFPALHKARPAPSPGT
LPACSEGLPASDTEDGPDREKPAIPKRLRKSLPPGLLRRVSSTWTTTTSATGLPTLEPAP
VRRDRSASIKAHEGPSSVSTTNPEAWNSSVLMTLTKSRSFSSSYAVSATNHLNAKRQVRA
GLLAKISPLSSPCPSPVQGTPASSPVSKSSGGQFPDSADATGQLGLNSHKALAYTQSAPD
LSPQGPPTPPAVCSSCGRPFSQGNTTDAQLERNTSGISSPGRTDDAAQVTSDYETNNSDS
SDIVQNEDEVEASKEPLRKGSPCSPYAPEAVIFVDKPILAPEPLVMDNLDSLMGQLNTWN
FPIFDLVEKIGRKCGRILSQVSYRLFEDMGLFEAFKIPVKEFMNYFHALENGYREIPYHN
RIHATDVLHAVWYLTTQPVPGLPTSLNDHGSASDSDSDSGLPHGHTGYVFSKMYMAGEER
SGCLAGHIPALELMALYVAAAMHDYDHPGRTNAFLVATSAPQAVLYNDRSVLENHHAAAA
WNLFMSRPEYNFLINLDHVEFKHFRFLVIEAILATDLKKHFDFVAKFNAKVNEEVGIDWT
NENDRLLVCQMCIKLADINGPAKCKELHLQWTDGIVNEFYQQGDEEASLGLPISPFMDRS
APQLANLQESFISHIVGPLCHSYDSAGLMPGKWVEDDADELGGDPDGHPEDGEEEEDDDG
QSTPEGEADENAESSRKPKFQRRKIHCQITQHLLQNHKMWKQEIEREQRLSGAGGRGKGG
PDAAGPAQPAETIQAITEEDEDRGRGRGEESTAAQPAQ
NT seq
2637 nt
NT seq
+upstream
nt +downstream
nt
atgaagggagaaggctttagggacacacaagcagacagtggtggacaaatttcagtgcga
atcggtgttcgacatattctgaaacaaagtacctttcaccaactttatcctccaaagctg
actggtcatcctgaatgggagcacaggcgaggaccccggggatcccagggctcggggacg
agcgtgccggtggacatcgcggtgatgggggaggcccacgggctgatcacggacctgctg
gcggacccctccctgccgcccaacgtgtgtacggctctgcggaccgtcagcaacctgctg
agcgcccagctcaccttcccggccctgcacaaggcccggcccgcgccctcacccgggacc
ctgcccgcctgctcggagggcctgcccgcctccgacaccgaggacggaccggatcgggag
aagccggccattcccaagcgcctgaggaagagtctcccgccggggctgctgaggcgcgtc
tcgtccacgtggaccacgacgacgtcggccacgggcctgcccaccctggagccggccccc
gtgaggagagaccgcagcgccagcatcaaagcccacgaagggccttcttctgtcagcact
actaatcccgaggcatggaacagctccgtcctgatgaccctcaccaaaagccggtcgttc
tcttcgtcctacgccgtgtccgccacaaaccacctgaacgccaagcggcaggtccgagcg
ggtctcctggcgaaaatttccccgctgtcgtccccgtgcccctcgccggtccagggcacc
cccgccagcagccccgtcagcaagagctcgggcgggcagtttccggactcggccgacgcg
accggtcagctgggcctcaactctcacaaggcgttggcctacacccagagcgcgccggac
ctttctccccaaggcccgcccacccctcctgccgtctgcagcagctgtggaagacctttt
agccaaggcaacactacggacgcgcagttggagaggaacacttcagggatttcttccccg
ggcaggacagatgacgcagcgcaagtgacctcggactacgaaaccaacaacagcgacagc
agcgacatcgtccagaacgaggacgaggtggaggcctccaaagagccgctgagaaagggg
tcgccctgcagcccctacgcccccgaggccgtcatcttcgtggataaacccattcttgct
cccgaacccctcgtcatggataatttggattcactaatggggcagctaaacacttggaat
tttcccatcttcgatttggtggaaaagatcggacgcaagtgtggccggatcctcagtcag
gtgtcctacaggcttttcgaagacatgggactttttgaagcttttaaaattccagtgaag
gaattcatgaactactttcacgccctagagaacggctatcgagagatcccttatcacaac
agaatccacgccaccgacgtgctgcacgccgtgtggtacctcaccacccagcccgtgccc
ggcctgcccaccagcctcaacgaccacggatcggccagtgattcagactcggacagcggg
ctcccgcacggccacacgggctacgtcttctccaagatgtacatggcgggcgaggagcgg
tccggctgcctggccggacacatccccgccctggagctgatggccctctacgtggccgcc
gccatgcacgactacgaccacccgggaaggaccaacgccttcctcgtggccaccagcgcc
ccccaggccgtgctatacaacgaccggtcggttctggagaaccaccacgctgccgccgcg
tggaacctcttcatgtctcgcccagagtataatttcctgatcaacctcgaccacgtggag
ttcaaacatttccgcttcctcgtcatcgaggccatcttggccaccgatctgaagaaacac
ttcgacttcgtggcaaaattcaatgccaaggtgaacgaagaagtcggaatcgattggacc
aacgagaacgaccgcctgctggtctgccagatgtgcataaagctggcggacatcaacggc
cccgccaaatgcaaggagcttcacctgcagtggacggacggcatcgtcaacgagttttac
cagcagggtgacgaagaagccagcctgggcctccccatcagcccgttcatggaccgctcg
gctcctcagctggccaacctccaggagtccttcatctcccacatcgtcggaccgctgtgc
cactcctacgactcggccggcctgatgcccgggaagtgggtggaggacgacgccgacgag
ctggggggcgaccccgacgggcaccccgaggacggggaggaggaagaggacgacgacggg
cagagcacccccgaaggggaagctgacgagaacgcggaatcctcaagaaagccaaagttc
cagaggaggaaaattcactgccagatcacgcagcacctgctgcagaaccacaagatgtgg
aagcaggagatcgagagagagcaacgcctgagcggggccgggggccggggtaagggcgga
ccggacgccgcgggcccggcccaaccggcggaaaccatccaagccatcacggaggaggat
gaagacagagggagaggccggggagaggagagtaccgctgcccagccggcccagtga
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