Ornithorhynchus anatinus (platypus): 100091139
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Entry
100091139 CDS
T01045
Symbol
ERBB2
Name
(RefSeq) receptor tyrosine-protein kinase erbB-2
KO
K05083
receptor tyrosine-protein kinase erbB-2 [EC:
2.7.10.1
]
Organism
oaa
Ornithorhynchus anatinus (platypus)
Pathway
oaa01521
EGFR tyrosine kinase inhibitor resistance
oaa01522
Endocrine resistance
oaa01524
Platinum drug resistance
oaa04010
MAPK signaling pathway
oaa04012
ErbB signaling pathway
oaa04020
Calcium signaling pathway
oaa04066
HIF-1 signaling pathway
oaa04151
PI3K-Akt signaling pathway
oaa04510
Focal adhesion
oaa04520
Adherens junction
oaa04530
Tight junction
oaa05200
Pathways in cancer
oaa05205
Proteoglycans in cancer
oaa05206
MicroRNAs in cancer
oaa05212
Pancreatic cancer
oaa05213
Endometrial cancer
oaa05215
Prostate cancer
oaa05219
Bladder cancer
oaa05223
Non-small cell lung cancer
oaa05224
Breast cancer
oaa05226
Gastric cancer
oaa05230
Central carbon metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
oaa00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
100091139 (ERBB2)
04012 ErbB signaling pathway
100091139 (ERBB2)
04066 HIF-1 signaling pathway
100091139 (ERBB2)
04020 Calcium signaling pathway
100091139 (ERBB2)
04151 PI3K-Akt signaling pathway
100091139 (ERBB2)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
100091139 (ERBB2)
04520 Adherens junction
100091139 (ERBB2)
04530 Tight junction
100091139 (ERBB2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
100091139 (ERBB2)
05206 MicroRNAs in cancer
100091139 (ERBB2)
05205 Proteoglycans in cancer
100091139 (ERBB2)
05230 Central carbon metabolism in cancer
100091139 (ERBB2)
09162 Cancer: specific types
05212 Pancreatic cancer
100091139 (ERBB2)
05226 Gastric cancer
100091139 (ERBB2)
05219 Bladder cancer
100091139 (ERBB2)
05215 Prostate cancer
100091139 (ERBB2)
05213 Endometrial cancer
100091139 (ERBB2)
05224 Breast cancer
100091139 (ERBB2)
05223 Non-small cell lung cancer
100091139 (ERBB2)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
100091139 (ERBB2)
01524 Platinum drug resistance
100091139 (ERBB2)
01522 Endocrine resistance
100091139 (ERBB2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
oaa01001
]
100091139 (ERBB2)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
oaa04147
]
100091139 (ERBB2)
04090 CD molecules [BR:
oaa04090
]
100091139 (ERBB2)
Enzymes [BR:
oaa01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
100091139 (ERBB2)
Protein kinases [BR:
oaa01001
]
Receptor tyrosine kinases (RTK)
EGFR family [OT]
100091139 (ERBB2)
Exosome [BR:
oaa04147
]
Exosomal proteins
Exosomal proteins of breast cancer cells
100091139 (ERBB2)
CD molecules [BR:
oaa04090
]
Proteins
100091139 (ERBB2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Recep_L_domain
GF_recep_IV
Pkinase
Furin-like
TM_ErbB1
ABC1
Stevor
Haspin_kinase
Tcell_CD4_C
DUF4381
APH
Kinase-like
Motif
Other DBs
NCBI-GeneID:
100091139
NCBI-ProteinID:
XP_028931763
Ensembl:
ENSOANG00000002175
UniProt:
F7AL47
LinkDB
All DBs
Position
11:13230692..13258620
Genome browser
AA seq
1251 aa
AA seq
DB search
MDLPRGHCYFWGLLLALLTPAVGSTQVCTGTDMKLQPPASPETHVEMLRRLYQHCHVVQG
NLELTYLPAHTDLSFLQTIEEVHGYVLIAHSLVSFVPLQRLRVVRGTQLYEERYALAVLE
NGPRGLAGAPAHAGLRELQLRSLTEILKGGVLIQGNPQLCHQDTVLWEDVVYRHNEPAVF
NIDSNRSRICGPCSSSCKSQKCWGEGAQNCQSLTSTICTSGCARCKGPLPTDCCHEQCAA
GCTGPKHSDCLACLNFNHSGTCELHCPPLVIYNSDMFESIPNPGGRYTFGASCVTACPYN
YLATEVGSCTLVCPLDNHEVTTEDGTQRCEKCNKPCPKVCYGLGREDLRGVRAVTAKNIE
SFKGCRKLFGSLAFLPESFAGDPLTNTLPLKPDQLKVFENLEEITGYLFISAWPESLSDL
SVFQNLRLIRGRVLHNGAYSLTLQHLGIRWLGLRSLREVSSGLALIHHNARLCFIDTVPW
DHLFRNPHQALLSSANRPTNECVSEGQSCNQLCAQGKCWGPGPSQCVSCSQFLRGQECVE
ECRVHHGSPREYVRERRCLPCHQECQPQNGTETCFGSEADECVACAHYKDPPFCVETCPS
GLKHDLSLVPIWKFPDEDGICQICPTNCTHSCAVLDAHGCPAEQKPSPVPSIIAGAVGVL
LAVVLILATGIWIKRRRQQERKHTMRRLLQETELVEPLTPSGALPNQAQMRILKETELKK
VKVLGSGAFGTVYKGIWIPDGENVKIPVAIKVLRENTSPKANKEILDEAYVMAGVGSPYV
SRLLGICLTSTVQLVTQLMPYGCLLDYVRENKERLASQDLLNWCVQIAKGMSYLEEVRLV
HRDLAARNVLVKSPNHVKITDFGLARLLDIDETEYHADGGKVPIKWMALESILRRRFTHQ
SDVWSYGVTVWELMTFGAKPYDGIPAREIPDLLEKGERLPQPPICTIDVYMIMVKCWMID
SECRPRFRELVAEFSRMARDPQRFVVIQNEELSGPASPMDSTFYGSLLDEDEMQDLVDAE
EYLVPHQGFFSPGPAAPTAGRRHPSSIGSGGELAVEAEGPEEPPRSPSDLSQGAGSDVFD
GETGTGVAKGQQGPPARENSLLQRYSEDPTSLPAPEADGYVVPHAGDPPPEYVNQLEPRP
PPPSPLECPLASGPLRPATSTLERPKGPAPGRNGLVKDAFGGGPFAGAVENPEYLAPRPA
PLRAFDNLYYWDQGPPEPGAPPNGFAATPTAENPEYLGLAESVSHPKDLAV
NT seq
3756 nt
NT seq
+upstream
nt +downstream
nt
atggatctgccccgcggccactgctacttttggggtctcctcctggccctgctgaccccg
gccgtgggcagcacgcaagtatgcacgggcacggacatgaagctgcagccgccggccagc
ccggagactcacgtggagatgctgcggcgactgtaccagcactgccatgtggtgcagggg
aacctggagctcacctacctccctgcccacactgatctctccttccttcagaccatcgag
gaggtgcatggctacgtgctgatcgcccacagcctggtgagcttcgtgccgctgcagcgg
ctgcgggtggtgcggggcacgcagctgtacgaggaacgctacgctctggccgtgctggag
aacggcccccgcggccttgccggggcccccgctcacgccggcctccgcgaactgcagctc
cgcagcctcacggagatcctgaaaggaggggtcctgatccaggggaacccccagctgtgc
caccaggacacggtgctgtgggaagacgtcgtctaccgacacaacgagccagccgtcttc
aacatcgatagtaaccgcagccgcatctgcggcccctgctcctcatcctgtaagtcccag
aaatgctggggagaaggtgcccagaattgccagagcctgaccagtaccatctgcaccagc
ggctgtgcccgctgtaagggacccctgcctaccgactgctgtcatgagcagtgtgcggca
ggctgcaccggtcccaagcactccgactgcctggcttgcctcaacttcaaccacagcggc
acctgtgagctgcattgcccacctctggtcatctacaactcggacatgtttgagtcgatc
cccaatcccggcggtcgctacacctttggggccagctgtgtcaccgcgtgcccctacaac
tacctggctacggaagtgggctcctgcaccctagtgtgtcccctggacaaccacgaagtc
accaccgaggatgggacccagcggtgtgaaaaatgcaacaagccatgtcccaaagtgtgc
tacgggctgggcagagaagacctgcgaggagtccgagccgtcaccgccaaaaacatcgag
agcttcaaggggtgcaggaagctctttgggagcttggccttcctgcctgagagcttcgct
ggggaccccctgaccaacaccctcccgctgaagcccgaccagctcaaggtcttcgagaac
ctggaggagatcacaggttacctgttcatctcggcctggccggaaagcctgtcagacctc
agcgtcttccagaacctgcggctcatccgggggagagtgctgcataatggggcctactcc
ctgaccctgcagcacctgggcatcagatggctggggctgcgctcgctacgtgaggtgagc
agcgggctggcgctgatccatcacaacgcccgcctctgcttcatcgacaccgtgccctgg
gaccatctcttccgcaacccccaccaggccctgctctccagtgccaatcggcccacgaat
gagtgtgtgagcgaagggcagtcttgcaaccagctgtgtgcccagggcaagtgctggggc
cctggcccttcccagtgtgtcagctgcagccaattcctgaggggtcaggagtgtgtggag
gaatgccgtgtccaccatggctcccctcgagagtacgtgagggagaggcgctgcctgccg
tgccaccaagagtgccagccgcagaacggcacagagacctgcttcggatcggaagcggac
gagtgcgtggcttgtgcccactataaggatccgcctttctgcgtggagacctgccccagc
ggcctcaaacacgacctctccttggtgcccatctggaagttcccggatgaggacggcatc
tgccagatctgccccaccaactgcacccactcctgcgctgtgctggatgcccacggatgc
ccggcggagcagaagcccagcccagtgccgtccatcatcgcgggggcggtgggcgtgctg
ctcgcggtggtcctcattctggccaccggcatttggatcaagcgaaggaggcagcaggag
cggaaacacaccatgcggcggctgctgcaggagaccgagctggtggagccgctgacgccc
agcggggcgctgcccaaccaggcccagatgcgcattctgaaagagacggagctcaagaaa
gtgaaggtcctgggctcgggtgcctttgggacggtctacaagggcatctggatcccagac
ggggagaacgtgaagatcccggtggctattaaggtgttacgggaaaacacatctcccaag
gccaacaaggagatcctggacgaagcgtacgtgatggccggggtgggcagcccctatgtc
tcccgtctcctgggcatctgcctgacgtccacggtgcagctggtgacccagctcatgccc
tacggctgcctcctggactacgtgagagagaacaaggaacgcctggcttcccaggacctg
ctcaactggtgtgtgcagatcgccaaggggatgagctacctggaggaggtgcggctggtg
caccgggatctggccgcccgcaacgtgctggtcaagagccccaaccacgtcaagatcact
gacttcggcctggcccggttgttggacatcgatgagacggagtaccacgcggatggaggc
aaggttcccatcaagtggatggccctggagtcgattctccgccggcgcttcacccatcag
agtgacgtctggagctacggcgtgacggtgtgggagctgatgacgtttggggcgaagccg
tacgacgggatcccggcccgagagatccccgacctgctggagaagggggagcgcctgccc
cagccccccatctgcaccatcgacgtctacatgatcatggtcaagtgctggatgatcgac
tcggagtgccgcccacgtttccgggaactggtagccgagttctcccgcatggctcgggac
ccccagcgtttcgtcgtcatccagaacgaggagctgtcgggccccgccagccccatggac
agcaccttctacggctcgttgctggacgaagatgagatgcaggacctggtggacgcggag
gagtacctggtcccccaccagggcttcttcagccccgggcccgcggcccccaccgccggc
cgccgccacccctcctccattgggagtggtggagagctggcggtggaggcggaggggccc
gaggagcccccgcggtccccgtcggacctgtcgcagggcgccggctcggacgtgttcgac
ggggagaccgggacgggggtggccaaggggcagcagggtccccccgcccgggaaaacagc
ctcctgcagcgctacagcgaggaccccaccagcctccctgcccccgaggccgacggctac
gtcgtcccccacgccggggaccccccgccagagtacgtgaaccaactggaaccccggccc
ccacccccctcgcccctggaatgccccctggcatccggcccgctgaggccggcgacctcc
accctggagcgccccaagggcccggcccccgggaggaacgggctggtcaaggacgcgttc
ggcggaggccccttcgcgggggccgtggagaaccccgagtacctggccccccggcccgcc
cccctccgggccttcgacaacctctactactgggaccagggcccccccgagcccggggcg
ccccccaatggctttgcggccacgcccacggccgagaaccccgagtacctaggcctggct
gagtccgtgagccaccccaaggacctggcagtatga
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integrated database retrieval system
