Ornithorhynchus anatinus (platypus): 100092266
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Entry
100092266 CDS
T01045
Symbol
NPC1
Name
(RefSeq) NPC intracellular cholesterol transporter 1 isoform X1
KO
K12385
Niemann-Pick C1 protein
Organism
oaa
Ornithorhynchus anatinus (platypus)
Pathway
oaa03265
Virion - Ebolavirus, Lyssavirus and Morbillivirus
oaa04142
Lysosome
oaa04979
Cholesterol metabolism
Brite
KEGG Orthology (KO) [BR:
oaa00001
]
09120 Genetic Information Processing
09125 Information processing in viruses
03265 Virion - Ebolavirus, Lyssavirus and Morbillivirus
100092266 (NPC1)
09140 Cellular Processes
09141 Transport and catabolism
04142 Lysosome
100092266 (NPC1)
09150 Organismal Systems
09154 Digestive system
04979 Cholesterol metabolism
100092266 (NPC1)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
02000 Transporters [BR:
oaa02000
]
100092266 (NPC1)
Transporters [BR:
oaa02000
]
Solute carrier family (SLC)
SLC65: NPC-type cholesterol transporter
100092266 (NPC1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
NPC1_MLD
NPC1_N
Sterol-sensing
Patched
MMPL
Folate_rec
Motif
Other DBs
NCBI-GeneID:
100092266
NCBI-ProteinID:
XP_028924174
Ensembl:
ENSOANG00000012193
LinkDB
All DBs
Position
7:20862789..20915449
Genome browser
AA seq
1282 aa
AA seq
DB search
MRGPAGLRLLGLWAGLLALGPKPVFSQSCIWYGECGIASGDKRYNCEYSGPPIPLPEDGY
DLIQELCPGLFFGNVSLCCDVQQLHTLKDKLQLPLQFLSRCPSCFYNLMNLFCELTCSPY
QGQFLNVTTTGDFVDPVSNITKKNVETLEYYIGKSFADAMYGACRDVEAPSSNDKALGLL
CGRDAKDCNATNWIEYMFNKDNGQAPFTITPIFSDVSIRGMIPMSNATRGCNESVDETTG
PCSCQDCSIVCGPKPQPLPPPVPWRIFGLDAMYVIMWLSYMGFLFVFFGAFFGVWCYRKR
YFVSEYAPIDSNIAFSVNANSDKGEASRCERLGEMFESGLRWAFSRWGSLCVRHPLPVVV
ASLAFIAACCSGLASVRITTNPVDLWSASGSQARREKEYFDTRFGPFYRTEQLIIRAPNT
SRHTFSPYPSGTDVPFGPPLDKTILHKVLDLQTAIENITASYGNETVRLRDICLAPLAPY
NDNCTIMSLLNFFQNSHSVLDHERGDGFFVYADYHTHFLYCVRAPTSLNDTSLLHDPCLG
TFGGPVFPWLVLGGYDDQNYNNATALVITFPVNNYHNDTEKLRRAEAWEKEFIRFVRDYK
DPNLTISFSAERSIEDELNRESNSDIFTVVISYAVMFLYISLALGHIKSFSRLLVDSKIS
LGIAGILIVLSSVACSLGIFSYAGIPLTLIVIEVIPFLVLAVGVDNIFILVQTFQRDQRL
QGETLDAQMGRILGEVAPSMFLSSFSETVAFFLGGLSTMPAVHTFSLFAGMAVFIDFLLQ
ITFFVSLLGLDVKRQERNRLDILCCVRGGDEAAGGQPSQGYLFQFFKNVYSPLLLKDWMR
PLIISVFVGILSFSIAVLNKVEIGLDQSLSMPDDSYVMDYFKALGQYLHAGPPVYFVLEE
GHDYTTLEGQNMVCGGMGCNNNSLVQQIFNAAELDNYTRIGFAPSSWIDDYFDWVKPQSS
CCRVYNGTDLFCNASVVDPSCVRCRPLTPEGKQRPQGSDFLHFLPMFLSDNPNPKCGKGG
HAAYSSAVNLANGSTSIGATYFMTFHTVLKTSSDFIDAMQKARTVAQNITESVGLPEGGY
RVFPYSVFYVFYEQYLTIVGDTIFNLGVSLGAIFLVTAVLLGCEVWAAVVLCLTIAMILV
NMFGVLWLWGISLNAVSLVNLVMSCGISVEFCSHITRAFTLSTRGSRVERAEEALANMGS
SVFSGITLTKFGGIVVLAFSKSQIFQIFYFRMYLAMVLLGATHGLIFLPVLLSYIGPPVN
RAKCRAAQERSKGTERERLLYF
NT seq
3849 nt
NT seq
+upstream
nt +downstream
nt
atgcggggtccggcggggttgcggctgttggggctgtgggccgggctgctggcgctgggc
cccaagccggtattttcccaatcgtgcatttggtatggggagtgtgggatagcctctgga
gacaagaggtataactgtgaatattccggtccaccgataccattgccagaagatggatac
gacttaatccaggaactctgtccaggtcttttcttcggtaacgttagcctttgttgcgat
gtgcagcagcttcacaccctgaaagacaagctgcagctgccgctacagttcctgtccagg
tgtccgtcctgcttctacaacctgatgaacctattctgcgagctgacgtgcagcccctac
cagggccagttcctgaacgtcaccacgacgggagacttcgtggaccccgtcagcaatata
accaaaaagaacgtcgaaaccctggagtactacatcgggaagagctttgccgacgccatg
tacggtgcctgtcgcgacgtggaggctccgtccagcaacgacaaggccctggggctgctg
tgcgggagagacgccaaggactgcaacgccaccaactggatcgaatacatgttcaacaag
gacaacgggcaggcgcctttcaccatcacgcccatcttctccgacgtttccatccgaggg
atgatccccatgagcaacgcaaccagaggctgcaacgaatccgtggacgagaccaccgga
ccgtgtagctgccaggattgttccatcgtgtgcggtcccaagccccagcccctgccccct
cctgtcccatggaggatctttggtttggatgccatgtatgtcatcatgtggctttcttac
atgggctttctgtttgtgttcttcggagcgttttttggagtctggtgctacaggaaacgg
tatttcgtctccgagtacgcacccattgacagcaatatagctttttcggtcaacgctaac
agtgacaaaggtgaggcctcccgctgtgagcgtctgggggagatgttcgagagcggcttg
aggtgggcattttcccggtgggggtctctctgcgtccgccacccgttgcccgtcgtggtg
gcatccctggcgttcatcgcggcctgctgctcgggcctggcgtccgtccggatcaccacg
aatcccgtggacctgtggtcggcctccggcagccaagcccgccgggagaaggaatacttc
gacacgcgcttcggccccttttaccggacggagcagctgatcatccgggcccccaatacg
tcccggcacaccttctccccgtacccctctggtaccgacgtgcccttcgggccgccgctc
gacaaaaccatactgcacaaggtgctcgacttgcagacggccatcgagaacatcacggct
tcctacggcaacgagaccgtccgtctccgagacatctgcctggctcccctggccccctac
aatgacaactgcaccattatgagcctgctgaacttcttccagaacagtcactccgtcctc
gaccatgagagaggggatggtttctttgtctacgcagattaccacacccactttctgtac
tgcgtccgggcccccacgtccctgaacgacacgagtttgctccacgacccctgcctgggc
acgtttggagggccggtgtttccctggctggtgttggggggctatgatgaccaaaactac
aacaacgccacagccctggtcatcacctttcccgtcaacaactaccacaacgacacagag
aagctgcgcagagcggaggcgtgggaaaaagaattcatccgcttcgtccgagactacaag
gacccaaacctcaccatctccttctctgccgagcgcagcatcgaagacgagctgaaccga
gagagcaacagcgacatcttcacggtcgtcatcagctatgccgtcatgttcctctatatt
tccctagcgctggggcacatcaagagcttcagcaggcttctggtggattctaaaatctct
ctgggcatcgctggcatcctgatcgtgttgagctcggtggcctgttccctggggatcttc
agctacgcgggaatccccctcacgctcatcgtgatcgaagtcatcccgttcctcgtgctc
gccgtcggagtagataacatcttcatcctcgtccagacgtttcagcgagaccagcgcctt
caaggggagacgctcgatgcccagatgggccggatcctgggagaagtggctcccagcatg
ttcctgtcatcgttttcggagaccgtggccttcttcttagggggattgtcgaccatgcca
gcggtgcacaccttctccctctttgccggaatggccgtcttcatcgatttcctcctgcaa
atcaccttcttcgtgagcctcctgggactggacgtgaagcgtcaagagagaaaccgtctg
gacattctgtgctgcgtccgaggtggagacgaggcggcgggcggccagccttcccagggc
tacttgtttcagttcttcaaaaacgtctattctcccctcttgctgaaagactggatgcgg
cccctcataatatccgtattcgtgggcatcttgtcattcagcatagccgtgctcaacaag
gtggaaatcggcctggaccagtctctctcgatgccggacgactcgtacgtgatggattac
ttcaaggccctcggtcagtacctgcacgcgggccccccggtgtacttcgtgctggaagaa
ggccatgactacacgactctggaaggccagaacatggtgtgcggtggaatgggatgtaac
aacaactctcttgtgcagcagattttcaatgcagcagagctagacaattatacgaggatc
ggcttcgcgccctcttcctggatcgatgattattttgactgggtgaagccccagtcttcc
tgctgcagagtctataacggcacggatctgttctgcaatgcttcagtcgtcgacccctcc
tgcgtccgctgccgccccttgaccccggaaggcaagcagaggcctcaggggtccgacttc
ctgcacttcctgcccatgttcctctcggacaaccccaaccccaaatgcggtaaagggggc
cacgcagcctactcctccgcggtcaacctcgccaacggcagcacgagcatcggtgccacc
tacttcatgaccttccacaccgtgctcaagacctcctccgacttcatcgacgccatgcag
aaagcccggaccgtcgcccagaacatcaccgagtccgtgggcctcccggagggtggctat
cgggtcttcccttacagcgtgttctacgtcttctacgagcagtacctgaccatcgtgggg
gacacgatctttaacctgggcgtgtccctgggggccatcttcctggtgacggcggtgctc
ctgggctgcgaggtgtgggcggcggtggtgctctgcctcaccatcgccatgatcctcgtc
aacatgtttggggtcctgtggctctggggcatcagcctgaacgcagtgtcgctggtcaac
ctggtcatgagctgcgggatctcggtggagttctgcagccacatcaccagggcgttcacc
ctgagcacccggggcagccgcgtggagcgggcggaagaggcgctcgccaacatgggcagc
tcggtatttagtgggatcacactgaccaaatttggagggattgtggtgttggcgttttcc
aagtctcagattttccagatcttctacttccggatgtacttggccatggtcctgctgggg
gccacccacggcctcatcttcctcccggtcctactcagttacataggacctccagtaaac
agagcaaaatgccgcgccgcccaggagcgatctaaaggtactgagcgggagcggctcctc
tacttttag
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