KEGG   Ornithorhynchus anatinus (platypus): 100681261
Entry
100681261         CDS       T01045                                 
Symbol
CACNA1B
Name
(RefSeq) voltage-dependent N-type calcium channel subunit alpha-1B isoform X1
  KO
K04849  voltage-dependent calcium channel N type alpha-1B
Organism
oaa  Ornithorhynchus anatinus (platypus)
Pathway
oaa04010  MAPK signaling pathway
oaa04020  Calcium signaling pathway
oaa04721  Synaptic vesicle cycle
oaa04723  Retrograde endocannabinoid signaling
oaa04725  Cholinergic synapse
oaa04726  Serotonergic synapse
oaa04727  GABAergic synapse
oaa04728  Dopaminergic synapse
oaa04930  Type II diabetes mellitus
oaa05016  Huntington disease
oaa05020  Prion disease
oaa05022  Pathways of neurodegeneration - multiple diseases
oaa05032  Morphine addiction
oaa05033  Nicotine addiction
oaa05207  Chemical carcinogenesis - receptor activation
Brite
KEGG Orthology (KO) [BR:oaa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    100681261 (CACNA1B)
   04020 Calcium signaling pathway
    100681261 (CACNA1B)
 09150 Organismal Systems
  09156 Nervous system
   04727 GABAergic synapse
    100681261 (CACNA1B)
   04725 Cholinergic synapse
    100681261 (CACNA1B)
   04728 Dopaminergic synapse
    100681261 (CACNA1B)
   04726 Serotonergic synapse
    100681261 (CACNA1B)
   04723 Retrograde endocannabinoid signaling
    100681261 (CACNA1B)
   04721 Synaptic vesicle cycle
    100681261 (CACNA1B)
 09160 Human Diseases
  09161 Cancer: overview
   05207 Chemical carcinogenesis - receptor activation
    100681261 (CACNA1B)
  09164 Neurodegenerative disease
   05016 Huntington disease
    100681261 (CACNA1B)
   05020 Prion disease
    100681261 (CACNA1B)
   05022 Pathways of neurodegeneration - multiple diseases
    100681261 (CACNA1B)
  09165 Substance dependence
   05032 Morphine addiction
    100681261 (CACNA1B)
   05033 Nicotine addiction
    100681261 (CACNA1B)
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    100681261 (CACNA1B)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04040 Ion channels [BR:oaa04040]
    100681261 (CACNA1B)
Ion channels [BR:oaa04040]
 Voltage-gated cation channels
  Calcium channel, voltage-gated (Cav)
   100681261 (CACNA1B)
SSDB
Motif
Pfam: Ion_trans Ca_chan_IQ GPHH PKD_channel
Other DBs
NCBI-GeneID: 100681261
NCBI-ProteinID: XP_028910158
Ensembl: ENSOANG00000011856
LinkDB
Position
X4:3645082..3820338
AA seq 2395 aa
MVRFGDDPLGRYGGGGGGGPAGGVRPNSRPGPGGPGGGGGGVGGPGGPGGGGGLGGPGGV
QPAQRPPYKQSKAQRTRAMALYNPIPVKQNCFTVNRSLFVFSEDNIIRKYAKRITEWPPF
EYMILATIIANCIVLALEQHLPDGDKTPMSERLDDTEPYFIGIFCFEAGIKIIALGFVFH
KGSYLRNGWNVMDFVVVLTGILATAGTDFDLRTLRAVRVLRPLKLVSGIPSLQVVLKSIM
KAMVPLLQIGLLLFFAIVMFAIIGLEFYMGKFHKACFPNSTDPEPEPVGDFPCGLESPAR
VCEEGTTCRTYWPGPNFGITNFDNILFAILTVFQCITMEGWTDILYNTNDAAGNTWNWLY
FIPLIIIGSFFMLNLVLGVLSGEFAKERERVENRRAFLKLRRQQQIERELNGYLEWIFKA
EEVMLAEEDKNAEEKSPLDGRATSAGPADTGGGAGGGSCNMLKRATIKKSKNDLIHAEEG
EDHFTDICSVGSPFARASLKSGKNDSSSYFRRKEKMFRFFIRRMVKAQTFYWIVLCVVAL
NTLCVAMVHYNQPQRLTNALYFAEFVFLGLFLTEMSLKMYGLGPRNYFHSSFNCFDFGVI
VGSIFEVIWAVVKPGTSFGISVLRALRLLRIFKVTKYWNSLRNLVVSLLNSMKSIISLLF
LLFLFIVVFALLGMQLFGGQFNFQDETPTTNFDTFPAAILTVFQILTGEDWNAVMYHGIE
SQGGVSKGMFSCVYFIVLTLFGNYTLLNVFLAIAVDNLANAQELTKDEEEMEEATNQKLA
LQKAKEVAEVSPMSAANISIAAFVKQTRGTVSHSSSASSVNSPKQQNAAKAKSVWEQRTS
QIRLHNFRASCEALYSELDPEDRVRYATSLHIRPDMKTHLDRPLVVEPRTAGGPAGPGPA
GPEAGPEPGPGRDPRPAAAAADGPDPPRRHHRHRDRDRAWDQEKADGAKEEKGEAGARRE
ADGHRPHRSRSKEAAGHKDGPRRAHRRGSGDEGADREHRRHRAHRHPAEPQAKEGNGTAH
GAKAERRARHRGGSRAGTRDGESGAKGEPGDEAHRRHRPRHRGTAAHEAADKDDGEKDGE
PAEKDVRNHRPKENQCEIEVVVPTHTLPSTCLQKVPEHPEDVDNQKNVDRMTQPSPPDNT
TTVNIPVTVTAPPGDTTVIPMNSVEFDSKMEEKKDVDGDDLMRSGPRQILPYSSMFCLSP
TNLLRRFCHYIVNMRYFEMVILMVIALSSIALAAEDPVWADSPRNNALKYMDYIFTGVFT
FEMVIKMIDLGLLLHPGSYFRDLWNILDFIVVSGALVAFAFSGTKGKDINTIKSLRVLRV
LRPLKTIKRLPKLKAVFDCVVNSLKNVLNILIVYMLFMFIFAVIAVQLFKGKFFYCTDES
KELERDCRGQYLDYEKEEEVEAQPRQWKKYDFHYDNVLWALLTLFTVSTGEGWPTVLKHS
VDATYEEQGPSPGFRMELSIFYVVYFVVFPFFFVNIFVALIIITFQEQGDKVMSECSLEK
NERACIDFAISAKPLTRYMPQNKQSFQYKMWKFVVSPPFEYFIMAMIALNTVVLMMKFYD
APHGYEIMLKCLNVVFTSMFSMECVLKIIAFGVLNYFRDAWNVFDFVTVLGSITDILVTE
IADTNNFINLSFLRLFRAARLIKLLRQGYTIRILLWTFVQSFKALPYVCLLIAMLFFIYA
IIGMQVFGNIALDDETSINRHNNFRTFLQALMLLFRSATGEAWHEIMLSCLSNRECDPAS
HLKNECGSDFAYFYFVSFIFLCSFLMLNLFVAVIMDNFEYLTRDSSILGPHHLDEFIRVW
AEYDPAACGRISYNDMFEMLKHMSPPLGLGKKCPARVAYKRLVRMNMPISNEDMTVHFTS
TLMALIRTALEIKLAPAGMKQHQCDAELKKEITSVWANLPQKTLDLLVPPHKPDEMTVGK
VYAALMIFDFYKQNKNVREPGQQQAGVLLQMCSASQNHPLKVRVSRVLQKQKSLASLNNG
GALPSQAGGSLNVSVSCGAQPTQDECFKTRTALEHGHSEEISAKPPGKQAVELHEMGPSV
LDGGEPQPGLESQGRAASMPRLATETQPIADTSPMKRSISTLAPQRPSAMPGPEDPLERA
PPDPHSGGGHHHHHHRCHRRRDRKQKSMDKGPNQLTDGEAVPSNELSAGQPGETPGRPEA
RKQERGRSQERKLHSSSSSSEKQRFYSCDRFGSRDHPQPKSSDGSRPGSPTGGQGQGLHR
QGSGSVNGSPLLSTSGASTPGRGGRRQLPQTPLTPRPSITYKTANSSPVHFCGPQAGLPG
FSPGRLSRGLSEHDALLRGGPPGQPPAPVARIGSDPYLGHRGPPEDTLTFEEAVATNSGR
SSRTSYVSSLTSQPHHGLRVPNGYHCAPGLGPAPASGQGRARHGYHHQADGNDWC
NT seq 7188 nt   +upstreamnt  +downstreamnt
atggttcgcttcggagacgaccctctgggccgctatgggggcgggggcgggggcggcccg
gccggaggggtccggcccaacagccggccggggcccggaggccccgggggaggaggcggc
ggggtcggcgggcccggagggcccggaggaggaggaggcctgggggggccggggggcgtc
cagcccgcccagcggccgccctacaagcagtccaaggcgcagcgcacccgggccatggcg
ctgtacaaccccatccccgtcaagcagaactgcttcaccgtcaaccgctccctcttcgtc
ttcagcgaggacaacatcatccgcaagtacgccaagcgcatcaccgagtggcctccgttt
gaatatatgattctagcgacaatcatcgccaactgcatcgtcctggcactggagcagcac
ctgcctgacggagacaagacccccatgtccgagcgcctggacgacaccgaaccctacttt
attggaatattttgctttgaggccgggataaaaatcatcgccctgggatttgttttccat
aaaggctcctacctgcgcaacggctggaacgtgatggatttcgtggtcgtcctcacggga
attctagccaccgccggcaccgactttgacctccggaccctgagggccgtccgtgtcctc
cggccgctgaagctcgtgtcggggatcccaagcttgcaggtggtgctgaagtcgatcatg
aaagccatggtgcccctgctgcagatcggcctgctcctcttcttcgccatcgtaatgttc
gccatcatcggcctggagttctacatgggcaagttccacaaagcctgcttccccaactcc
acagatccggaacccgaaccggtgggagactttccctgcggattggaatccccggccagg
gtgtgcgaggaagggaccacctgccggacttactggccgggacccaacttcgggatcacc
aacttcgacaacatcctgttcgccatcctcaccgtcttccagtgcatcaccatggagggc
tggaccgacatcctgtacaacaccaacgacgcggctgggaacacctggaattggctctac
ttcatcccgctcatcatcatcgggtccttcttcatgctcaacctggtgctgggcgttctg
tccggggaattcgccaaagaacgcgagagggtggagaaccgccgggccttcctcaaactc
cgcaggcaacagcagatcgagcgagagctcaacggctacttggagtggatcttcaaagcg
gaggaagtcatgctggccgaggaggacaagaacgcggaggagaagtccccgttggacggg
agggccacgtctgcggggccggcggacacgggcggcggtgccggcggaggcagctgcaac
atgctgaaaagagccaccataaagaaaagtaaaaacgatctgatccacgcggaagaaggg
gaagaccatttcaccgatatctgctctgtgggttctccgttcgctcgggccagcctgaag
agcgggaagaacgacagctcctcctacttccggaggaaagagaagatgttccgcttcttc
atccgccgcatggtgaaagcccagaccttctactggatcgtgctgtgcgtcgtcgccttg
aacacgctgtgcgtggccatggtgcactacaatcagccgcagagactcaccaacgcctta
tattttgccgaatttgttttcctggggctcttcctcactgagatgtccctgaagatgtac
ggactggggcctagaaattacttccactcgtccttcaactgctttgatttcggggtcatc
gtcgggagcatctttgaggtcatctgggccgtggtgaagccgggaacgtccttcggcatc
agcgtgctaagagctctccgcctgctcaggatcttcaaagtcaccaagtactggaattcc
ctgaggaacttggtggtgtccctgctgaactccatgaagtccatcatcagcttgctgttc
ctgctcttcctcttcatcgtggtgttcgccctgctcgggatgcagctcttcggggggcag
tttaactttcaagacgaaaccccgaccaccaacttcgataccttccccgcggccatcctg
accgtctttcagatcctgacgggggaagattggaacgcggtgatgtatcacgggatcgaa
tcccaaggcggagtcagcaaaggcatgttctcctgcgtttacttcatcgtcctgacgctg
ttcggaaactacaccctcctgaacgtcttcttggccattgccgtggacaatctggccaac
gcccaggagctgaccaaggacgaagaggagatggaagaagccaccaaccagaaactcgcg
ttgcaaaaggccaaggaggtagccgaagttagtcccatgtctgcagctaacatttccatc
gcagcttttgtaaagcaaactcgaggcactgtatctcacagctcgtctgcctccagcgta
aattcacccaagcagcagaacgccgccaaggccaagtccgtgtgggagcagcgcaccagc
cagatccggctgcacaacttccgggccagctgcgaggcgctctacagcgagctggacccc
gaggaccgcgtgcgctacgccacctccctgcacatccggcccgacatgaagacccacctg
gaccgtcccctggtggtggagccccggaccgcggggggcccggccggccccgggcccgcc
ggccccgaggccgggccggagccgggcccgggccgggaccccaggccggccgccgccgcc
gccgacgggcccgacccgccccgccggcaccaccggcaccgggacagggaccgggcctgg
gaccaggagaaggccgacggggccaaggaggagaagggggaggccggggcccgcagggag
gcggacgggcaccggccccaccgcagccgcagcaaggaggccgccggccacaaggacggg
ccccgcagggcccaccgccgcggctcgggggacgagggcgccgacagggagcaccggcgc
caccgggcccaccgccatccggccgagccccaggccaaggagggcaacgggaccgcccac
ggggccaaggcggagcgccgggcccgccaccggggcggctcgcgggccggaacccgcgac
ggggagtccggggccaagggcgagcccggcgacgaggcccaccggcgccacaggcccagg
cacagggggacggccgcgcacgaggcggccgacaaggacgacggggagaaggacggggag
cccgccgagaaggacgtccgcaaccaccggcccaaggagaaccagtgtgagatcgaggtg
gtggtccccacccacacgctgcccagcacctgcctgcagaaggtccccgagcaccccgag
gacgtggacaaccagaagaatgtggaccggatgacccagccgtcgccgccggacaacacc
accacggtgaacatcccggtgaccgtgaccgctccccctggggacaccacggtcattccc
atgaacagcgtggaattcgacagtaagatggaagagaagaaagacgtggacggggatgac
ttgatgaggagcggacccaggcagatcctcccctacagctccatgttctgtttgagtcct
accaacctgctccgacgtttctgccactacatcgtcaacatgcgctactttgagatggtc
atcctcatggtcatcgcgctgagcagcatcgcgctggccgccgaagacccagtgtgggct
gattccccacgcaacaacgctctgaagtacatggattacatcttcacgggcgtctttacc
ttcgagatggtgatcaagatgattgacctgggcctgctgcttcaccctggctcctatttc
cgagatctgtggaacatcctggactttattgtggtcagtggagcgctggtggctttcgca
ttctcaggaaccaaaggcaaagacatcaacaccatcaagtcgctgcgggtcctccgagtc
ctgcggcccctgaagaccatcaagcgattgcccaaactgaaggccgtcttcgactgcgtg
gtgaactccctgaagaacgtgctcaacatcctgatcgtctacatgctgttcatgttcatc
ttcgccgtcatcgcggtgcagctcttcaagggcaagttcttctactgcaccgacgagtcc
aaagaactggagcgggattgcaggggccagtacctggactacgaaaaggaagaggaagtg
gaggctcagcctaggcagtggaagaaatatgacttccactacgacaacgtgctctgggcc
ctgctgacgctcttcaccgtgtccacgggcgaggggtggccgacggtcttgaaacactct
gtggacgccacctacgaggagcagggccccagccccggcttccggatggagctgtccatc
ttctacgtggtgtatttcgtcgtcttcccgttcttcttcgtcaacatcttcgtggctctg
atcatcatcaccttccaggagcagggggacaaagtgatgtcggagtgcagcttggagaag
aacgagagagcctgcatcgacttcgccatcagcgctaagcccctgacccgctacatgccc
cagaacaagcagtccttccagtacaagatgtggaagttcgtcgtgtctccgcccttcgaa
tatttcatcatggccatgatcgccctcaacaccgtggtcctgatgatgaagttctacgac
gccccccacgggtacgagatcatgctgaagtgtctgaatgtcgtgtttacatcaatgttc
tccatggagtgcgtcttgaaaatcatagcctttggggtgctgaactacttccgagatgcc
tggaacgtctttgatttcgtcacggttctgggcagtatcaccgatattttagtaacggag
attgcggacacgaacaacttcatcaacctcagcttcctgaggctcttccgggcagcccgg
ctcatcaaacttctgaggcaagggtacaccatccgcatcctgctctggaccttcgtccag
tccttcaaggctctgccctacgtctgcctgctgatcgccatgctgttcttcatctacgcc
atcatcggcatgcaggtgttcggcaacatcgccctggacgacgaaaccagcatcaatcgg
cacaacaacttccgcaccttcttacaagccctgatgctgctcttcaggagcgccacggga
gaagcctggcacgagatcatgctgtcgtgcctgagcaaccgcgagtgcgacccggcctcc
cacctgaagaacgaatgtgggagcgacttcgcttacttttacttcgtctccttcatcttc
ctctgttcctttctgatgctgaacctcttcgtggcggtgatcatggacaacttcgagtac
ctgacccgagactcgtccatcctgggcccccaccacctggacgagttcatccgcgtctgg
gccgagtacgacccggccgcctgcggacgaatcagttacaatgacatgtttgagatgctg
aagcacatgtcccctccgctaggtttggggaagaaatgcccagctcgtgttgcttataag
cgccttgtgaggatgaatatgcccatctctaacgaggacatgacggtccacttcacctcc
acgctcatggccctcatcaggacggctctggagatcaagttggctccagctgggatgaag
cagcatcagtgtgacgcagagctgaagaaggagattacgtccgtgtgggccaacctgccc
cagaagaccttggacttgctggtgccgccacacaagccggatgagatgacggtggggaag
gtgtatgcagccttgatgatatttgacttctacaagcagaacaagaacgtacgagagcca
ggccagcaacaagctggagtcctcttacagatgtgttccgcatcccagaatcaccccctg
aaggtccgagtgtcccgagtgctccagaagcagaagagcctggcctcgctcaacaacgga
ggggccctcccaagccaggcgggcggcagcctcaacgtttcggtgtcctgtggggctcag
cccacccaggacgagtgcttcaagaccaggacggcgctggagcacggccactctgaggag
atctcggccaagcctccgggcaaacaggcggtggagttgcacgagatgggccccagcgtc
ctcgacggcggcgagccccagccggggctggagagccagggacgggcggcctccatgccc
cgcctcgccacagagacccagcccatcgcagacacgagccccatgaagcgatccatctcc
acgctggcccctcagcgcccctccgcgatgcccggccccgaggaccccctggagcgggcc
cccccggacccccacagcggcggcggccaccatcaccaccaccaccgctgccatcgccgc
cgggacaggaagcagaaatccatggacaagggccccaaccagctgacggacggagaggcg
gtcccgagcaacgagctgtccgcgggccagccgggcgagacgcccggccggcccgaggcc
cggaagcaggagcggggtcgctcccaggagaggaagctgcactcctcctcctcctcgtcc
gagaagcaacgcttttactcgtgcgaccgcttcggcagccgggaccacccgcagcccaag
tcctcggacgggagccggccgggttcccccaccggagggcaggggcaggggctccacaga
cagggtagtggttcggttaacgggagccctctgctgtcgacgtctggtgctagtaccccg
ggccgtggggggcggaggcagctcccccagacccccctgaccccccgccccagcatcacg
tacaagacggccaactcctcgccggtccacttctgcggcccgcaggccggcctgcccggc
ttctcccccggccggctgagccgcggcctgtcggagcacgacgccctgctgcggggcggc
cccccgggccagcccccggcccccgtggcccggatcggctcggacccctacctgggccac
cggggcccgccggaggacacgctcaccttcgaggaagccgtcgccaccaactcgggccgc
tcctcccggacttcctacgtctcctcgctgacctcccagccgcaccacggcctccgggtc
cccaacggctaccactgcgccccggggctcgggccggccccggcgtccggccagggacgg
gcccggcacggctaccaccaccaggccgacgggaacgactggtgctag

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