Ornithorhynchus anatinus (platypus): 103169124
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Entry
103169124 CDS
T01045
Symbol
PAK4
Name
(RefSeq) serine/threonine-protein kinase PAK 4 isoform X1
KO
K05734
p21-activated kinase 4 [EC:
2.7.11.1
]
Organism
oaa
Ornithorhynchus anatinus (platypus)
Pathway
oaa04012
ErbB signaling pathway
oaa04014
Ras signaling pathway
oaa04360
Axon guidance
oaa04510
Focal adhesion
oaa04660
T cell receptor signaling pathway
oaa04810
Regulation of actin cytoskeleton
oaa05170
Human immunodeficiency virus 1 infection
oaa05206
MicroRNAs in cancer
oaa05211
Renal cell carcinoma
Brite
KEGG Orthology (KO) [BR:
oaa00001
]
09130 Environmental Information Processing
09132 Signal transduction
04012 ErbB signaling pathway
103169124 (PAK4)
04014 Ras signaling pathway
103169124 (PAK4)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
103169124 (PAK4)
09142 Cell motility
04810 Regulation of actin cytoskeleton
103169124 (PAK4)
09150 Organismal Systems
09151 Immune system
04660 T cell receptor signaling pathway
103169124 (PAK4)
09158 Development and regeneration
04360 Axon guidance
103169124 (PAK4)
09160 Human Diseases
09161 Cancer: overview
05206 MicroRNAs in cancer
103169124 (PAK4)
09162 Cancer: specific types
05211 Renal cell carcinoma
103169124 (PAK4)
09172 Infectious disease: viral
05170 Human immunodeficiency virus 1 infection
103169124 (PAK4)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
oaa01001
]
103169124 (PAK4)
Enzymes [BR:
oaa01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
103169124 (PAK4)
Protein kinases [BR:
oaa01001
]
Serine/threonine kinases: STE group
STE20 family
103169124 (PAK4)
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
PBD
Kinase-like
ABC1
Pkinase_fungal
hnRNP_Q_AcD
KIND
RIO1
Motif
Other DBs
NCBI-GeneID:
103169124
NCBI-ProteinID:
XP_028920623
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All DBs
Position
5:3142669..3162610
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AA seq
620 aa
AA seq
DB search
MFSKKKKRLEISAPSNFEHRVHTGYDQREQKFTGLPRQWQGIIEESAKRPKPLVDPVCIT
AIQRGNQKTIVRGNKAPKDGALTLLLEDFENMSVTRSNSLRRDSPPCPPRRDPPAQENGL
AGVRPPAPRASSQQPRGQEPAPPEHPKPPPEGRTGAPERGGRRDPPQGEGAGRPARREGP
EKRPKSSYAGGAGGPQPPRDKRPLSGPSLGTPHLPAADGAAETARQGGRPFNTYPRADTD
PGRGSAPQGESGPGRAHQTASNGPAGGPPSSRGPPRARQAAEPSGPGPAPHASDPQLARG
VPPGPQPPPPPAAGPQQPRSPQREPQRVSHEQFRAALQMVVDPGDPRSDLDNFIKIGEGS
TGVVCIATVRSSGELVAVKKMDLRKQQRRELLFNEVVIMRDYQHENVVELYNSYLVGDEL
WVVMEFLEGGALTDIVTHTRMNEEQIAAVCLAVLKALSVLHAQGVIHRDIKSDSILLTHD
GRVKLSDFGFCAQVNKEVPRRKSLVGTPYWMAPELISRLPYGPEVDIWSLGVMVIEMVDG
EPPYFNEPPLKAMKMIRDNLPPKLKNIHKVSPSMKGFLDRLLVRDPAQRATANELLKHPF
LGKAGPPASIVPLMRQNRMR
NT seq
1863 nt
NT seq
+upstream
nt +downstream
nt
atgttcagcaagaagaagaagcgcctggagatctcggccccgtccaactttgagcaccgg
gtccacacgggctacgaccagcgggagcagaagttcaccgggctgccgcgtcaatggcag
ggcatcatcgaggagtcggccaagcggcccaaacctctcgtcgaccccgtctgcatcacc
gccatccagcgcggcaaccaaaagaccatcgtgcgagggaacaaggcgccgaaggacggg
gccctgacgctgctgctggaggactttgagaacatgtcggtgacgcggtccaactccctg
cgccgggacagccccccctgcccccctcgccgggacccgccggcccaggagaacgggctg
gccggggtccggcccccggcgccccgggcctcctcccagcagccccggggccaggagccc
gcgccccccgaacaccccaagcccccgcccgagggcaggaccggagcccccgagcggggc
gggcggagggacccgccgcagggcgagggggccgggcggccggcacggcgggagggcccc
gagaagaggcccaagtcgtcgtacgccgggggggccggcggcccccagcccccccgggac
aagcggcccctgtcgggccccagcctcggcaccccccacctcccggccgccgacggcgcg
gctgagacggcccggcagggcggacggccctttaacacgtacccgcgtgccgacacggac
cccggccggggctcggccccccagggggagtccgggccgggccgggcccaccaaacagcc
tccaacggccccgccggcggcccgccctcctcccgggggccgccccgcgcccggcaggcc
gccgagccgtccggcccgggcccggccccgcacgcctcggacccccagctggcccgcggg
gtcccgccggggccccagcccccgccgcccccggccgccgggccgcagcagccgcgctcg
ccgcagcgggagccccagcgcgtgtcacacgagcagttccgcgcggcgctgcagatggtg
gtggaccccggcgacccccgctccgacctggacaacttcatcaagatcggcgagggctcc
accggcgtcgtctgcatcgccaccgtccggagcagcggcgagctcgtggccgtcaaaaag
atggacctgaggaagcagcagcgccgggagctgctcttcaatgaggtggtgatcatgcgg
gactatcagcacgagaacgtggtggagctgtacaacagctacctggtgggcgacgagctg
tgggtggtcatggagttcctggagggaggggccctcaccgacatcgtcactcacaccagg
atgaacgaggaacagatcgcggccgtgtgcctggcggtcctgaaggcgctctctgtcctc
cacgcccagggagtcatccaccgtgacatcaagagcgactccatcctgctgacccacgac
ggcagggtgaagctgtcggacttcggcttctgcgcgcaggtgaacaaggaggtgccgcgc
aggaagtcgctggtggggaccccatattggatggcccccgaactcatctcccgcttaccc
tacgggcccgaggtggacatctggtcgctgggggtgatggtgatcgagatggtggatggg
gagcccccctacttcaatgagccccccctgaaggcaatgaagatgatccgcgacaacctt
ccccccaagctgaaaaacatccacaaggtgtctccttccatgaagggcttcctggaccgg
ctgctggtgcgagacccggcccagagggccacggccaacgaactgctgaagcacccgttc
ctgggcaaggccgggcccccggccagcatcgtcccgctcatgcggcagaaccggatgaga
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