Ornithorhynchus anatinus (platypus): 114811053 Help Entry 114811053         CDS       T01045                                  Symbol TLR4 Name (RefSeq) toll-like receptor 4   KO K10160   toll-like receptor 4 Organism oaa  Ornithorhynchus anatinus (platypus) Pathway oaa04064   NF-kappa B signaling pathway oaa04066   HIF-1 signaling pathway oaa04145   Phagosome oaa04151   PI3K-Akt signaling pathway oaa04217   Necroptosis oaa04613   Neutrophil extracellular trap formation oaa04620   Toll-like receptor signaling pathway oaa04621   NOD-like receptor signaling pathway oaa04936   Alcoholic liver disease oaa05132   Salmonella infection oaa05133   Pertussis oaa05134   Legionellosis oaa05135   Yersinia infection oaa05140   Leishmaniasis oaa05142   Chagas disease oaa05144   Malaria oaa05145   Toxoplasmosis oaa05146   Amoebiasis oaa05152   Tuberculosis oaa05161   Hepatitis B oaa05162   Measles oaa05164   Influenza A oaa05170   Human immunodeficiency virus 1 infection oaa05171   Coronavirus disease - COVID-19 oaa05205   Proteoglycans in cancer oaa05235   PD-L1 expression and PD-1 checkpoint pathway in cancer oaa05321   Inflammatory bowel disease oaa05323   Rheumatoid arthritis oaa05417   Lipid and atherosclerosis Brite KEGG Orthology (KO) [BR:oaa00001]  09130 Environmental Information Processing   09132 Signal transduction    04064 NF-kappa B signaling pathway     114811053 (TLR4)    04066 HIF-1 signaling pathway     114811053 (TLR4)    04151 PI3K-Akt signaling pathway     114811053 (TLR4)  09140 Cellular Processes   09141 Transport and catabolism    04145 Phagosome     114811053 (TLR4)   09143 Cell growth and death    04217 Necroptosis     114811053 (TLR4)  09150 Organismal Systems   09151 Immune system    04613 Neutrophil extracellular trap formation     114811053 (TLR4)    04620 Toll-like receptor signaling pathway     114811053 (TLR4)    04621 NOD-like receptor signaling pathway     114811053 (TLR4)  09160 Human Diseases   09161 Cancer: overview    05205 Proteoglycans in cancer     114811053 (TLR4)    05235 PD-L1 expression and PD-1 checkpoint pathway in cancer     114811053 (TLR4)   09172 Infectious disease: viral    05170 Human immunodeficiency virus 1 infection     114811053 (TLR4)    05161 Hepatitis B     114811053 (TLR4)    05171 Coronavirus disease - COVID-19     114811053 (TLR4)    05164 Influenza A     114811053 (TLR4)    05162 Measles     114811053 (TLR4)   09171 Infectious disease: bacterial    05132 Salmonella infection     114811053 (TLR4)    05135 Yersinia infection     114811053 (TLR4)    05133 Pertussis     114811053 (TLR4)    05134 Legionellosis     114811053 (TLR4)    05152 Tuberculosis     114811053 (TLR4)   09174 Infectious disease: parasitic    05146 Amoebiasis     114811053 (TLR4)    05144 Malaria     114811053 (TLR4)    05145 Toxoplasmosis     114811053 (TLR4)    05140 Leishmaniasis     114811053 (TLR4)    05142 Chagas disease     114811053 (TLR4)   09163 Immune disease    05323 Rheumatoid arthritis     114811053 (TLR4)    05321 Inflammatory bowel disease     114811053 (TLR4)   09166 Cardiovascular disease    05417 Lipid and atherosclerosis     114811053 (TLR4)   09167 Endocrine and metabolic disease    04936 Alcoholic liver disease     114811053 (TLR4)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:oaa04131]     114811053 (TLR4)   09183 Protein families: signaling and cellular processes    04054 Pattern recognition receptors [BR:oaa04054]     114811053 (TLR4)    04090 CD molecules [BR:oaa04090]     114811053 (TLR4)    00536 Glycosaminoglycan binding proteins [BR:oaa00536]     114811053 (TLR4) Membrane trafficking [BR:oaa04131]  Endocytosis   Phagocytosis    Toll-like receptors     114811053 (TLR4) Pattern recognition receptors [BR:oaa04054]  Membrane-bound pattern recognition receptors   Toll-like receptors    114811053 (TLR4) CD molecules [BR:oaa04090]  Proteins   114811053 (TLR4) Glycosaminoglycan binding proteins [BR:oaa00536]  Hyaluronan   Cell surface receptors    114811053 (TLR4) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  LRR_8 LRR_4 TIR TIR_2 LRR_5 ThsB_TIR LRR_9 Blo-t-5 Motif Other DBs NCBI-GeneID:  114811053 NCBI-ProteinID:  XP_028917935 Ensembl:  ENSOANG00000013202 LinkDB All DBs Position 4:28778309..28790013 Genome browser AA seq 861 aa AA seqDB search MTQVSVLGSSCDFHAYTSPPLFTKDARMKTPSLPIFALISSVLFWTCWIADQRKLCLEVV ANITYQCMELDLSEVPAEIPSSAQNLDLSFNPLGTLVPKGFSMLPDLRMLDLTRCQIQVI EDDAFRGLCNLSTLILTGNPVQRLGASAFSGLKMLQKLVAVEMQVVSLEDLPLGHLTALR ELNLGHNFIRSSKLPSYFAHLVSLQYLNLYKNKISMILLEDLNVLKQRQQPLLTLVLSLN NILNIELGSFEGLHLQALEMRGCFNDVNVTKTCINALAGLQVHQLVLGDFRENHNDMPED FGVFDGLCKVDIEEFRIVYYKGLIYNTNIFSNCLLNVSVLRVVSTSLNEVANLPAATRWQ TLHFNRCGFSEVPAKSLRPLTQLKELQITENDELKEFEQDFCLPNLESLDLSRNRLNFKS CCSETLFGTPRLKHLNLSFNFHIDITVNFMGLVELQYLDLQHSKLNGPGHFSAFVLLTKL IYLDISYTNTHIDSAGTFYGLESLQVLKMAGNTFHNRFLKDNFRNVTRLLYLDISNCQLE QVSHQAFTSLHQLQELNISHNKLLTFPVACAPLQSLKVLDCSFNLIAAPEEEALRSLSQT LVRLDLSQNPLDCFCDHLGFLQWVKDHRKQLWKPERMTCARPSDLANTLVLDFKPSVCEV KRILMWVSVVGVLAIAFIVVLVYKFYFHLMLLSGCKRYGPGGNTYDAFVIYSSQDEEWVR NELVKNLEEGVPPFQLCLHYRDFMPGVAITSNIIQEGFHKSRKVIVVVSKHFMESRWCSF EFEIAQTWQFLESQAGIILIVLQKVDKSQLQRRMGLSRYLHRNTYLEWEDNKISRHIFWR RLRNALLDGSVPSGIREKVGT NT seq 2586 nt NT seq  +upstreamnt  +downstreamnt atgactcaggtctctgtcctgggcagcagctgtgattttcatgcatatacctcacctcca ctcttcaccaaagatgccaggatgaaaacaccatctttgcccatctttgctttgatttca tcagtgctattctggacctgttggattgctgaccaacggaagctctgcttggaggttgtt gctaacattacataccaatgcatggaactggatctctctgaagtccctgctgagatccca tcttcggctcagaacctcgacctgagcttcaacccactgggaacattggttccaaagggc ttctcaatgctccctgacctgaggatgctggacctaaccagatgtcaaattcaggtgatt gaagatgatgctttccgaggtctatgcaatctgtccaccttgattctgactggcaatcct gtgcaaagattaggagcaagcgccttctctgggctgaagatgttacagaagctggttgcg gtggagatgcaggtggtatctctggaggatctgcccctgggacatctgactgcccttcgg gagctgaatttgggccataatttcatcagatcttccaaactaccctcgtattttgctcac ctggtctccttgcagtatttgaacctgtacaaaaataagatctcaatgatattgttagaa gacctgaatgttttgaaacaaagacagcagcctcttctcaccttagttctgtccttgaat aatatcctgaatattgaactaggctcctttgaggggcttcatctccaagcactggagatg cgaggttgttttaatgatgtgaatgtcacaaagacttgtatcaatgcactggctggtttg caagtccatcaacttgtccttggagactttagagaaaatcataatgacatgcctgaggac tttggtgtctttgatgggttgtgcaaggtggacattgaggagtttaggattgtttactat aagggcttaatctataataccaacattttttccaactgcctgctgaatgtttctgttctt agggtggtgtccacatctttaaatgaggtagccaacctcccagcggctaccagatggcaa accctacatttcaataggtgtggattttcagaggtacccgctaagtcacttagacctctc acccagcttaaggagctccagatcactgagaatgatgaactcaaggaatttgagcaggat ttttgtctgcccaatcttgaatccctggatctcagtcgaaaccgtcttaatttcaagagc tgctgttctgaaacgctgtttggcactccaagattgaagcacttgaacctgagcttcaac tttcatatcgacataacggtaaactttatggggctggtggagttgcagtacctggatctg cagcattcaaagttgaatggccctggccatttttctgcctttgtcttgcttacaaaactc atctaccttgatatttcctacaccaatacgcacattgactctgcaggcaccttctatggc ttggaaagcctccaagtactcaaaatggcaggtaacaccttccataacaggttcctaaag gataacttcagaaatgtgactcgcctgctttatctggacatttccaattgccagttggaa caggtgtcccatcaggcttttacttctctccatcagctgcaagaattgaatattagtcac aacaagctcctcacatttccagtcgcctgtgccccactccagtccctcaaggtcctggat tgcagtttcaatctcatagcagcacctgaagaagaagccctgagaagtttatcacagact ctggttcgcttggatctttcccagaatcctttggactgcttttgtgaccatctggggttt ctgcagtgggtcaaagaccatagaaagcagttatggaagcctgagcgaatgacctgtgcc agaccatccgatctagcaaacaccttagtcctggattttaagccctctgtctgtgaagtc aaaaggatcctgatgtgggtctctgttgttggggtgttggctatagctttcattgtggtc ttggtttataaattctatttccatctcatgctcctttcaggttgcaaaagatatggccca ggagggaacacctacgatgcttttgtcatctactccagccaggatgaggagtgggtgagg aacgagctagtgaagaatcttgaagaaggggtgcctccattccagctgtgccttcattat agagactttatgccaggggtggcgatcacctccaacatcatccaggaagggtttcacaag agccggaaagtcatcgtggttgtctccaagcacttcatggagagccggtggtgcagcttt gagttcgagattgctcagacttggcagttcctcgagagtcaggctggcatcatccttatt gtcctgcagaaagtggacaagtctcagcttcagcggcggatggggctgtctcgttatctc cacaggaacacttacctggagtgggaggacaataagatcagtcgacacatcttctggagg cggctcagaaatgccctcctggacggcagtgtgcccagtggaatcagggaaaaagtaggg acctaa

DBGET integrated database retrieval system