Ovis aries (sheep): 100145857
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Entry
100145857 CDS
T03117
Symbol
BCKDHA
Name
(RefSeq) 2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial
KO
K00166
2-oxoisovalerate dehydrogenase E1 component subunit alpha [EC:
1.2.4.4
]
Organism
oas
Ovis aries (sheep)
Pathway
oas00280
Valine, leucine and isoleucine degradation
oas00640
Propanoate metabolism
oas00785
Lipoic acid metabolism
oas01100
Metabolic pathways
oas01210
2-Oxocarboxylic acid metabolism
Module
oas_M00036
Leucine degradation, leucine => acetoacetate + acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
oas00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00640 Propanoate metabolism
100145857 (BCKDHA)
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
100145857 (BCKDHA)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
100145857 (BCKDHA)
Enzymes [BR:
oas01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.4 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
100145857 (BCKDHA)
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Motif
Pfam:
E1_dh
TPP_enzyme_C
DXP_synthase_N
Motif
Other DBs
NCBI-GeneID:
100145857
NCBI-ProteinID:
NP_001119816
UniProt:
A0A6P9FQE0
B2LSM3
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All DBs
Position
14:50096244..50114859
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AA seq
447 aa
AA seq
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MAVAAAAARVWRPSRGLGRAGLPLLRLLGARGLARSHTHRWQQQRHFSSLDDKPQFPGAS
AEFIDKLEFIQPNVISGIPIYRVMDRQGQIINPSEDPHLPQEKVLKFYKSMTLLNTMDRI
LYESQRQGRISFYMTNYGEEGTHVGSAAALDDTDLVFGQYREAGVLMYRDYPLELFMAQC
YGNVSDLGKGRQMPVHYGCRERHFVTISSPLATQIPQAVGAAYAAKRANANRVVICYFGE
GAASEGDAHAGFNFAATLECPIIFFCRNNGYAISTPTSEQYRGDGIAARGPGYGILSIRV
DGNDVFAVYNATKEARRRAVAENQPFLIEAMTYRIGHHSTSDDSSAYRSVDEVNYWDKQD
HPISRLRHHLQSRGWWDDEQEKAWRKQSRKKVMEAFEQAERKLKPNPNLIFSDVYQEMPA
QLRKQQESLARHLQTYGEHYPLDHFEK
NT seq
1344 nt
NT seq
+upstream
nt +downstream
nt
atggcggtggcggctgcggcggcgagggtttggagaccaagtcgaggcttgggacgggcg
ggcctcccgctcctgcggctgcttggggctcgtgggctggctagatctcatacccacagg
tggcagcaacagcggcacttctcgtccctggatgacaagccgcagttcccaggggcctca
gcggagttcatagacaagctcgagttcattcagcccaatgtcatctctgggatccccatc
taccgggtcatggaccggcagggccagatcatcaaccccagcgaggatccccatctgccc
caggagaaggtgctcaaattctacaagagcatgaccttgctaaacaccatggaccgcatc
ctctatgagtcccagaggcagggccgcatatccttctacatgaccaactatggcgaagag
gggacgcacgtgggcagcgcggcagccctggacgacacagacctagtgtttggccagtac
cgggaggcaggtgtgctcatgtaccgggactaccccctggagctgttcatggcccagtgc
tacggcaacgtgagtgacctgggcaaggggcgccagatgcccgtccactacggctgcagg
gagcgccacttcgtcaccatctcctctccactggccacgcagatcccccaggcggtcggg
gcagcctacgcagccaagcgggccaacgccaacagggtggtcatctgttacttcggagag
ggggcagccagtgagggggacgcccacgccggcttcaacttcgccgccaccctcgagtgc
cccatcatcttcttctgtcggaacaacggctacgccatctccacgcccacctcagagcaa
taccgcggggacggcattgcggctcgaggccccgggtacggcatcctctccatccgcgtg
gatggcaatgatgtgtttgccgtgtacaacgccaccaaggaggcccggcggcgggccgtg
gcggagaaccagcccttcctcattgaggccatgacctacaggatcgggcaccacagcacc
agtgatgacagctcggcgtaccgctcagtggacgaggtcaactactgggacaagcaggac
caccccatctcccggctgcggcatcacctgcagagccgcggctggtgggatgacgagcag
gagaaggcctggaggaagcagtcccgcaagaaggtaatggaagcctttgagcaggctgag
cggaagctgaagcccaaccccaacttgatcttctcggacgtgtatcaggagatgcctgcc
cagctccgcaagcagcaggagtctctggcacgtcacctccagacctacggcgaacactac
ccactggaccacttcgagaagtga
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