KEGG   Ovis aries (sheep): 100194428
Entry
100194428         CDS       T03117                                 
Symbol
MAPK13
Name
(RefSeq) mitogen-activated protein kinase 13
  KO
K04441  p38 MAP kinase [EC:2.7.11.24]
Organism
oas  Ovis aries (sheep)
Pathway
oas01522  Endocrine resistance
oas04010  MAPK signaling pathway
oas04015  Rap1 signaling pathway
oas04068  FoxO signaling pathway
oas04071  Sphingolipid signaling pathway
oas04114  Oocyte meiosis
oas04148  Efferocytosis
oas04218  Cellular senescence
oas04261  Adrenergic signaling in cardiomyocytes
oas04370  VEGF signaling pathway
oas04380  Osteoclast differentiation
oas04550  Signaling pathways regulating pluripotency of stem cells
oas04611  Platelet activation
oas04613  Neutrophil extracellular trap formation
oas04620  Toll-like receptor signaling pathway
oas04621  NOD-like receptor signaling pathway
oas04622  RIG-I-like receptor signaling pathway
oas04625  C-type lectin receptor signaling pathway
oas04657  IL-17 signaling pathway
oas04658  Th1 and Th2 cell differentiation
oas04659  Th17 cell differentiation
oas04660  T cell receptor signaling pathway
oas04664  Fc epsilon RI signaling pathway
oas04668  TNF signaling pathway
oas04670  Leukocyte transendothelial migration
oas04714  Thermogenesis
oas04722  Neurotrophin signaling pathway
oas04723  Retrograde endocannabinoid signaling
oas04728  Dopaminergic synapse
oas04750  Inflammatory mediator regulation of TRP channels
oas04912  GnRH signaling pathway
oas04914  Progesterone-mediated oocyte maturation
oas04917  Prolactin signaling pathway
oas04926  Relaxin signaling pathway
oas04932  Non-alcoholic fatty liver disease
oas04933  AGE-RAGE signaling pathway in diabetic complications
oas04935  Growth hormone synthesis, secretion and action
oas04936  Alcoholic liver disease
oas05014  Amyotrophic lateral sclerosis
oas05020  Prion disease
oas05022  Pathways of neurodegeneration - multiple diseases
oas05132  Salmonella infection
oas05133  Pertussis
oas05135  Yersinia infection
oas05140  Leishmaniasis
oas05142  Chagas disease
oas05145  Toxoplasmosis
oas05152  Tuberculosis
oas05161  Hepatitis B
oas05163  Human cytomegalovirus infection
oas05167  Kaposi sarcoma-associated herpesvirus infection
oas05169  Epstein-Barr virus infection
oas05170  Human immunodeficiency virus 1 infection
oas05171  Coronavirus disease - COVID-19
oas05205  Proteoglycans in cancer
oas05208  Chemical carcinogenesis - reactive oxygen species
oas05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
oas05415  Diabetic cardiomyopathy
oas05417  Lipid and atherosclerosis
oas05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:oas00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    100194428 (MAPK13)
   04015 Rap1 signaling pathway
    100194428 (MAPK13)
   04370 VEGF signaling pathway
    100194428 (MAPK13)
   04668 TNF signaling pathway
    100194428 (MAPK13)
   04068 FoxO signaling pathway
    100194428 (MAPK13)
   04071 Sphingolipid signaling pathway
    100194428 (MAPK13)
 09140 Cellular Processes
  09141 Transport and catabolism
   04148 Efferocytosis
    100194428 (MAPK13)
  09143 Cell growth and death
   04114 Oocyte meiosis
    100194428 (MAPK13)
   04218 Cellular senescence
    100194428 (MAPK13)
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    100194428 (MAPK13)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    100194428 (MAPK13)
   04613 Neutrophil extracellular trap formation
    100194428 (MAPK13)
   04620 Toll-like receptor signaling pathway
    100194428 (MAPK13)
   04621 NOD-like receptor signaling pathway
    100194428 (MAPK13)
   04622 RIG-I-like receptor signaling pathway
    100194428 (MAPK13)
   04625 C-type lectin receptor signaling pathway
    100194428 (MAPK13)
   04660 T cell receptor signaling pathway
    100194428 (MAPK13)
   04658 Th1 and Th2 cell differentiation
    100194428 (MAPK13)
   04659 Th17 cell differentiation
    100194428 (MAPK13)
   04657 IL-17 signaling pathway
    100194428 (MAPK13)
   04664 Fc epsilon RI signaling pathway
    100194428 (MAPK13)
   04670 Leukocyte transendothelial migration
    100194428 (MAPK13)
  09152 Endocrine system
   04912 GnRH signaling pathway
    100194428 (MAPK13)
   04914 Progesterone-mediated oocyte maturation
    100194428 (MAPK13)
   04917 Prolactin signaling pathway
    100194428 (MAPK13)
   04926 Relaxin signaling pathway
    100194428 (MAPK13)
   04935 Growth hormone synthesis, secretion and action
    100194428 (MAPK13)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    100194428 (MAPK13)
  09156 Nervous system
   04728 Dopaminergic synapse
    100194428 (MAPK13)
   04723 Retrograde endocannabinoid signaling
    100194428 (MAPK13)
   04722 Neurotrophin signaling pathway
    100194428 (MAPK13)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    100194428 (MAPK13)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    100194428 (MAPK13)
  09159 Environmental adaptation
   04714 Thermogenesis
    100194428 (MAPK13)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    100194428 (MAPK13)
   05208 Chemical carcinogenesis - reactive oxygen species
    100194428 (MAPK13)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    100194428 (MAPK13)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    100194428 (MAPK13)
   05161 Hepatitis B
    100194428 (MAPK13)
   05171 Coronavirus disease - COVID-19
    100194428 (MAPK13)
   05163 Human cytomegalovirus infection
    100194428 (MAPK13)
   05167 Kaposi sarcoma-associated herpesvirus infection
    100194428 (MAPK13)
   05169 Epstein-Barr virus infection
    100194428 (MAPK13)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    100194428 (MAPK13)
   05135 Yersinia infection
    100194428 (MAPK13)
   05133 Pertussis
    100194428 (MAPK13)
   05152 Tuberculosis
    100194428 (MAPK13)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    100194428 (MAPK13)
   05140 Leishmaniasis
    100194428 (MAPK13)
   05142 Chagas disease
    100194428 (MAPK13)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    100194428 (MAPK13)
   05020 Prion disease
    100194428 (MAPK13)
   05022 Pathways of neurodegeneration - multiple diseases
    100194428 (MAPK13)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    100194428 (MAPK13)
   05418 Fluid shear stress and atherosclerosis
    100194428 (MAPK13)
   05415 Diabetic cardiomyopathy
    100194428 (MAPK13)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    100194428 (MAPK13)
   04932 Non-alcoholic fatty liver disease
    100194428 (MAPK13)
   04933 AGE-RAGE signaling pathway in diabetic complications
    100194428 (MAPK13)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    100194428 (MAPK13)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:oas01001]
    100194428 (MAPK13)
Enzymes [BR:oas01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.24  mitogen-activated protein kinase
     100194428 (MAPK13)
Protein kinases [BR:oas01001]
 Serine/threonine kinases: CMGC group
  MAPK family [OT]
   100194428 (MAPK13)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr ABC1 RIO1 APH Kinase-like Kdo
Other DBs
NCBI-GeneID: 100194428
NCBI-ProteinID: NP_001132927
UniProt: B6Z9S6
LinkDB
Position
20:10181535..10189897
AA seq 366 aa
MSFTRKKGFYKQDVNKTAWELPKTYVSLTHIGSGAYGSVCSAIDKRSGEKVAIKKLSRPF
QSEIFAKRAYRELLLLKHMQHENVIGLLDVFTPASSLRNFHDFYLVMPFMQTDLQKIMGM
EFSEDKIQYLVYQMLKGLKYIHSAGVVHRDLKPGNLAVNEDCELKILDFGLARHTDVEMT
GYVVTRWYRAPEVILSWMRYNQTVDIWSVGCIMAEMLTGKTLFKGKDYLDQLTQILKVTG
VPGAEFVQKLNDKAAKSYIQSLPQXPRKDFSQLFPRASPQATDLLEKMLELDVDKRLTAS
QALAHPFFEPFRDPEEETEAQQPLEDSLERERLTVDEWKQHIYKEIVNFSPIARKDSRRR
SGMKLQ
NT seq 1101 nt   +upstreamnt  +downstreamnt
atgagcttcacccggaaaaagggcttctacaagcaggacgtcaacaagaccgcctgggag
ctgcccaagacctacgtgtccctgacgcacataggcagcggggcctatggctccgtgtgc
tcagccatcgacaagcggtcaggggaaaaggtggccatcaagaagctgagccggcccttc
cagtccgagatctttgccaagcgggcttatcgggagctgctgctgctgaaacacatgcag
catgagaacgtcattgggctcctggatgtcttcaccccagcctcctccctgcgcaacttc
catgacttctacctggtgatgcccttcatgcagacggacctgcagaagatcatggggatg
gagttcagtgaggacaagatccagtacctggtgtaccagatgctcaagggtcttaagtac
atccactcagctggggtcgtccacagggacctgaagccgggcaacctcgctgtgaacgag
gactgcgagctgaagatcttggattttgggttggcacggcatacggatgtggagatgacg
ggttacgtggtgacccgctggtaccgggcccctgaggtgattctcagctggatgcgttac
aaccagaccgtggacatctggtctgtgggctgtatcatggcagagatgctgacagggaag
acgctgttcaaggggaaagactacctggaccagctgacccagatcctgaaagtgactggg
gtgccgggtgccgagtttgtgcagaagctgaatgacaaggcggccaaatcctacatccag
tccctgccacaaagncccagaaaggatttctctcagctcttcccacgtgccagcccccag
gccacagacctgctggagaagatgctggagctggacgtggacaagcgcctgactgcctcg
caggccctcgcccaccccttctttgagcccttccgggaccctgaggaggagacagaggcc
cagcagccgctcgaagattccttagaacgcgagagactcacagtggacgaatggaagcag
cacatctacaaggagattgtgaacttcagccccattgcccggaaggactctcggcgccgg
agtggcatgaagttgcagtga

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