KEGG   Ovis aries (sheep): 100216465
Entry
100216465         CDS       T03117                                 
Symbol
ATF4
Name
(RefSeq) cyclic AMP-dependent transcription factor ATF-4
  KO
K04374  cyclic AMP-dependent transcription factor ATF-4
Organism
oas  Ovis aries (sheep)
Pathway
oas04010  MAPK signaling pathway
oas04022  cGMP-PKG signaling pathway
oas04137  Mitophagy - animal
oas04141  Protein processing in endoplasmic reticulum
oas04151  PI3K-Akt signaling pathway
oas04210  Apoptosis
oas04211  Longevity regulating pathway
oas04261  Adrenergic signaling in cardiomyocytes
oas04668  TNF signaling pathway
oas04720  Long-term potentiation
oas04722  Neurotrophin signaling pathway
oas04725  Cholinergic synapse
oas04728  Dopaminergic synapse
oas04911  Insulin secretion
oas04912  GnRH signaling pathway
oas04915  Estrogen signaling pathway
oas04918  Thyroid hormone synthesis
oas04922  Glucagon signaling pathway
oas04925  Aldosterone synthesis and secretion
oas04926  Relaxin signaling pathway
oas04927  Cortisol synthesis and secretion
oas04928  Parathyroid hormone synthesis, secretion and action
oas04932  Non-alcoholic fatty liver disease
oas04934  Cushing syndrome
oas04935  Growth hormone synthesis, secretion and action
oas05010  Alzheimer disease
oas05012  Parkinson disease
oas05014  Amyotrophic lateral sclerosis
oas05020  Prion disease
oas05022  Pathways of neurodegeneration - multiple diseases
oas05030  Cocaine addiction
oas05031  Amphetamine addiction
oas05034  Alcoholism
oas05161  Hepatitis B
oas05163  Human cytomegalovirus infection
oas05166  Human T-cell leukemia virus 1 infection
oas05203  Viral carcinogenesis
oas05207  Chemical carcinogenesis - receptor activation
oas05215  Prostate cancer
oas05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:oas00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04141 Protein processing in endoplasmic reticulum
    100216465 (ATF4)
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    100216465 (ATF4)
   04668 TNF signaling pathway
    100216465 (ATF4)
   04022 cGMP-PKG signaling pathway
    100216465 (ATF4)
   04151 PI3K-Akt signaling pathway
    100216465 (ATF4)
 09140 Cellular Processes
  09141 Transport and catabolism
   04137 Mitophagy - animal
    100216465 (ATF4)
  09143 Cell growth and death
   04210 Apoptosis
    100216465 (ATF4)
 09150 Organismal Systems
  09152 Endocrine system
   04911 Insulin secretion
    100216465 (ATF4)
   04922 Glucagon signaling pathway
    100216465 (ATF4)
   04912 GnRH signaling pathway
    100216465 (ATF4)
   04915 Estrogen signaling pathway
    100216465 (ATF4)
   04926 Relaxin signaling pathway
    100216465 (ATF4)
   04935 Growth hormone synthesis, secretion and action
    100216465 (ATF4)
   04918 Thyroid hormone synthesis
    100216465 (ATF4)
   04928 Parathyroid hormone synthesis, secretion and action
    100216465 (ATF4)
   04925 Aldosterone synthesis and secretion
    100216465 (ATF4)
   04927 Cortisol synthesis and secretion
    100216465 (ATF4)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    100216465 (ATF4)
  09156 Nervous system
   04725 Cholinergic synapse
    100216465 (ATF4)
   04728 Dopaminergic synapse
    100216465 (ATF4)
   04720 Long-term potentiation
    100216465 (ATF4)
   04722 Neurotrophin signaling pathway
    100216465 (ATF4)
  09149 Aging
   04211 Longevity regulating pathway
    100216465 (ATF4)
 09160 Human Diseases
  09161 Cancer: overview
   05207 Chemical carcinogenesis - receptor activation
    100216465 (ATF4)
   05203 Viral carcinogenesis
    100216465 (ATF4)
  09162 Cancer: specific types
   05215 Prostate cancer
    100216465 (ATF4)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    100216465 (ATF4)
   05161 Hepatitis B
    100216465 (ATF4)
   05163 Human cytomegalovirus infection
    100216465 (ATF4)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    100216465 (ATF4)
   05012 Parkinson disease
    100216465 (ATF4)
   05014 Amyotrophic lateral sclerosis
    100216465 (ATF4)
   05020 Prion disease
    100216465 (ATF4)
   05022 Pathways of neurodegeneration - multiple diseases
    100216465 (ATF4)
  09165 Substance dependence
   05030 Cocaine addiction
    100216465 (ATF4)
   05031 Amphetamine addiction
    100216465 (ATF4)
   05034 Alcoholism
    100216465 (ATF4)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    100216465 (ATF4)
  09167 Endocrine and metabolic disease
   04932 Non-alcoholic fatty liver disease
    100216465 (ATF4)
   04934 Cushing syndrome
    100216465 (ATF4)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:oas03000]
    100216465 (ATF4)
Transcription factors [BR:oas03000]
 Eukaryotic type
  Basic leucine zipper (bZIP)
   AP-1(-like) components, CRE-BP/ATF
    100216465 (ATF4)
SSDB
Motif
Pfam: bZIP_1 bZIP_2 DUF4407 DUF3450 KIF21A Asd-4 AAA_13 Laminin_II Fez1 ZapB OVT1
Other DBs
NCBI-GeneID: 100216465
NCBI-ProteinID: NP_001135990
UniProt: B6Z9S5
LinkDB
Position
3:216751096..216770443
AA seq 353 aa
MAEMSFLSSEVFVGDFVSPFDQSGLGAEESLGLLDDYLEVAKHFKPHGFSCDKAKAGSSE
RLAVDGLVSFSDNSTEDAFSGTDWMVEKMDLKEFDISDTLLSIDDLETMPDELLATLDDT
CDLFDPLLQETNKEPPEIVNPIGHLPESLPTIDQGAPFTFLQPLPPSPGALSSTPDHSFS
LELCSEVVISEGDSKPDSTTSITVIPQCIKEEDAHSDNDSGICMSPDSSVGSPQHSPSTS
RGSPNKSLLSPGALSGSSRPKPYDPPGEKMVAAKVKGERLDKKLKKMEQNKTAATRYPQK
KRAEQEALTGECKELEKKNEALKEKADSLAKEIQYLKDLIEEVRKAREKKRVP
NT seq 1062 nt   +upstreamnt  +downstreamnt
atggccgagatgagcttcctgagcagcgaggtgtttgtgggggacttcgtgtcccccttc
gaccagtcgggtttgggggctgaagagagcctaggtctcctagatgactacctggaggtg
gccaagcacttcaaacctcatgggttctcctgcgacaaggctaaggcaggctcctccgaa
cggctggctgtggatggattggtcagtttctcagacaacagcacggaggatgctttctcc
gggacagattggatggtggagaaaatggatttgaaggagtttgatattagtgataccctg
ttgagtatagatgacctggaaaccatgccagatgagctcttggccacgttggatgacacg
tgtgatctctttgatcccctactccaggagactaacaaggagccccccgagatagtgaac
ccaattggccatcttccagaaagtttacccacaattgaccagggtgcccccttcactttc
ttgcaacctcttcccccttccccaggggccctgtcttccactccagatcattcctttagt
ttagagctatgcagtgaagtggttatctctgaaggagatagcaagccagactccaccact
tccattactgtgatccctcagtgcataaaagaggaggatgcccactcagataacgacagt
ggcatctgtatgagccctgactcctctgtgggctctccccagcatagcccctccacctcc
aggggctctccaaataagagcctgctatctccaggtgccctcagtggctcttcccgcccc
aaaccttacgaccctcctggagagaagatggtagcagcaaaagtaaagggtgagagactg
gataagaagctgaagaaaatggagcagaacaagacagcagctactaggtacccccagaag
aagagggcagaacaggaggccctcactggggaatgtaaagagctagaaaaaaagaatgag
gctctgaaagagaaggcagattccttggccaaggagatccagtatcttaaagatctgata
gaagaggttcgcaaagcaagggagaagaaaagggtcccttag

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