Ovis aries (sheep): 100216476
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Entry
100216476 CDS
T03117
Symbol
HTT
Name
(RefSeq) huntingtin
KO
K04533
huntingtin
Organism
oas
Ovis aries (sheep)
Pathway
oas05016
Huntington disease
oas05022
Pathways of neurodegeneration - multiple diseases
Brite
KEGG Orthology (KO) [BR:
oas00001
]
09160 Human Diseases
09164 Neurodegenerative disease
05016 Huntington disease
100216476 (HTT)
05022 Pathways of neurodegeneration - multiple diseases
100216476 (HTT)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03019 Messenger RNA biogenesis [BR:
oas03019
]
100216476 (HTT)
04131 Membrane trafficking [BR:
oas04131
]
100216476 (HTT)
03029 Mitochondrial biogenesis [BR:
oas03029
]
100216476 (HTT)
Messenger RNA biogenesis [BR:
oas03019
]
Eukaryotic type
mRNA surveillance and transport factors
mRNA cycle factors
Common to processing body (P body) and stress granule
100216476 (HTT)
Membrane trafficking [BR:
oas04131
]
Endocytosis
Rab GTPases and associated proteins
Rab associated proteins
100216476 (HTT)
Mitochondrial biogenesis [BR:
oas03029
]
Mitochondrial quality control factors
Regulator of mitochondrial biogenesis
Other regulator of mitochondrial biogenesis
100216476 (HTT)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Htt_C-HEAT
Htt_N-HEAT
Htt_bridge
Htt_N-HEAT_1
HEAT
HEAT_EF3_N
HEAT_EZ
Motif
Other DBs
NCBI-GeneID:
100216476
NCBI-ProteinID:
NP_001136110
UniProt:
B7U9A4
LinkDB
All DBs
Position
6:complement(116327379..116449465)
Genome browser
AA seq
3127 aa
AA seq
DB search
MATLEKLMKAFESLKSFQQQQQQQQQQPPPPPPQPPQPPPPPQAQPPPQPPPPPPPPPVG
PAAAEEPLHRPKKELSATKKDRVNHCLTICENIVAQSLRNSPEFQKLLGIAMELFLLCSD
DAESDVRMVADECLNKVIKALMDSNLPRLQLELYKEIKKNGAPRSLRAALWRFAELAHLV
RPQKCRPYLVNLLPCLTRTSKRPEESVQETLAAAIPKIMASFGNFANDNEIKVLLKAFIA
NLKSSSPTVRRTAAGSVVSICQHSRRTQYFYSWLLSVLLGLLVPVEEEHPTLLILGVLLA
LRSLVPLLQQQVKDTSLKGSFGVTRKETEVSPSTEQLVQVYELTLHYTQHQDHNVVTGAL
ELLQQLLRTPPPELLRALTTAGGVRQLAAAKDEPGGRSRSGSIVELIAGGGSSCSPVLSR
KQKGKVLFGEAAPLEDDSESRSEGSSPAFSASAKGEAGGELAASSGVSTPGSTSSAADSA
GHGIITEQPRSQHTRQTDSVDLAACDLTSAATDGDEEDILSRSSSQMSAVPSDPAMDLND
GTQASSPISDSSQTTTEGPDSAVTPSDSSEIVLDGPDSQYPGMPAGQMQDEDGDATAVLP
DDAEAFRNSSIALQQAHLLKSMGHSRQASDSSVDKFVSREEAAEPGDPESKPWRVKGDIG
QSTDEDSAPLVHCVRLLSASFLLTGEKNALVPDRDVRVSVKALALSCVGAAVALHPESFF
SKLYRAPLDTVEFPEEQYVSDVLNYIDHGDPQVRGATAILCGTLVCSVLGRCRFHVAGWM
GAVRARTGNTFSLADCIPLLQKTLKDESSVTCKLACAAVRLCVMSLCSSSYSAWGLQLIT
DLLALRSSSYWLVRTELLETVAEIDFRLVSFLEAKAESLHRGAHHYTGRLKLQERVLSNV
VIHLLGDEDPRVRHVAAASLMRLVPKLFYKCDRGQADPVVVVARDQSSVYLALLMHEPQP
PSHLSVSAATRIYRGYNLLPSITDVTLENNLSRVIAAVSHELIMSTTRALTFGCCEALCL
LSTAFPVCIWSLGWHCGVPPLSASDESRKSCTVGMVTMILTLLSSAWFPLDLSAHQDALI
LAGNLLAASAPRSPRSSWASEDEASTAASKQEEAWPALGDRTLVPMVEQLFSHLLKVINI
CAHVLDDVAPGPAVKAALPSLTNPPSLSPIRRKGKEKEPGEQASVPVSPKKGGESSPASR
PPETSGPVATNKSSSLGSFCHLPSYLKLHDVLKATHANYKVTLDLQSSSEKVGGFLRSAL
DVLSQILELATLQDIGKCVEEILGYLKSCFSREPMMATVCVQQLLKTLFGTNLASQLDGL
SSHASKSQGRAQRLGSSSARPGLYHYCFMAPYTLFTQALADASLRNAAQAEQDQDTAGWF
DVLQKVSTQLKTNLTSVSKNRADKNAIHNHIRLFEPLVIKALKQYTTTTSVRLQKQVLAL
LAQLVQLRVNYCLLDSDQVFIGFVLKQFEYIEVGQFRESEAIIPNIFFFLVLLSYERYHS
KQIIGIPKIIQLCDGIMASGRKAVTHAIPALQPIVHDLFVLRGTNKADAGRELETQKEVV
VSMLLRLIQYHQVLEMFTLVLRQCHKESEDRWKRLSRQVADVILPMLAKQQVHIDSHEAL
GVLNTLFEILAPSSLRPVDMLLRSMFVTPDTLAVVSTVQLWVSGILAILRVLISQSTEDI
VLSRIQELSFSPNLVSCSTISRLRDGDSASAPEELSEGRQTKNLPEETFARFLLQLVGIL
LEDIVTKQLRVEVSEQQHTFYCQELGTLLMCLIHIFKSGTFRRITAAASRLLRDGADGGF
YSLESLNARVRSVIPTHPALVLLWCQILLLVGHTDYRWWAEVQQTPKRRSLSSTKSLSPE
TSGEDEDPDVASKLGMCNREIVRRGALILFCDYVCQNLHDSEHLTWLIVNHIQDLISLSH
EPPVQDFISAVHRNSAASGLFIQAIQSRCENLSTPTMLKRTLQCLEGIHLSQSGAVLTLY
VDKLLCTPLRALARVVETLACRRVEMLLAANLQSSTAQLPAEELIRIQEHLQSSGLAQRH
QRLYSLLDRLRLATAPGSHGPTPPVTSHPLDGDGPLALEAVNPDKDWYVQLVQAQCWTRS
DSALLEGAELVSRIPAGDLGAFVMHSEFNLSLLAPCLGLGMREISGGQRSPLFEAARMAT
LDRVTVVVQQLPAVHQAFQPFLPPQPATYWSKLDDLFGDAALYRTLTTLARALAQYLLVF
SRLPSHLQLPPEKERDTVKFVVMTLEALSWHLTHARVPLSLDLQAGLDCCCLALQLPGLW
SLLAAPNMVTHACSLIHCVRFILEAIVVQPGDQLLSPESRTSAPRSAREDGVDSDTQTPQ
YIAAACGMVAEMVECLPSVLALGHKRNSHTPAFLTPVLRNIIISLARLPLVNSYTRVPPL
VWKLGWSPKPGGDFGTVFPEIPVEFLQEKEVFKEFIYRINTLGWTSRTQFEETWATLLGV
LVTQPLVMEQEESPQEEDVERTQIHVLAVQAITSLVLSAMTVPVAGNPAVSCLEQQPRNK
PLKALDTRFGRKLSVIRGIVEQEIQAMVSRRENAATHHLYQAWDPVPSLAPATTGALISH
DKLLLQLNPERELGDMSYKLGQVSIHSVWLGNSITPLREEEWDEEEEEAEAPAPSSPPTS
PLNSRKHRAGVDIHSCSQFLLELYSRWILPSSSARRTPVTLISEVVRSLLVVSDLFTERN
QFEMMYLTLTELRKAHPSEDEILLQYLVPATCKAAAVLGMDKAVAEPVSRLLESALRSSH
LPSTMGALHGVLYVLECDLLDDTAKQLIPVVSDYLLSSLQGRAHCVNVHSQQHVLVMCAT
AFYLIENYPLDVGPEFSASIIQMCGVMLSGSEEATPSVVYHCVLRGLERLLLSEQLSRLD
AESLVKLSVDRVNVHSPHRAMAALGLMLTCMYTGKEKVSPGRASEPSPAAPDSESVIVAM
ERVSVLFDRIRKGFPCEARVVARVLPQFLDDFFPPQDVMNKVIGEFLSSQQPYPQLMATV
VYQVFQALHSAGQSSTVRDWVMLSLSNFTQRSPVAMATWSLSCFFVSASTSPWVSAILPH
VVSRMGKLEQVDVNLFCLVAADFYRHQIEEELDRRAFQSVFEVVAVPGNPYHHLLACLRS
VHKAATC
NT seq
9384 nt
NT seq
+upstream
nt +downstream
nt
atggcgaccctggaaaagctgatgaaggccttcgagtccctcaaatccttccagcagcag
cagcagcagcagcagcagcagccgcctccgccgccgcctcagcctcctcagccgccgccg
ccgccgcaggcgcagccgccgcctcagccgcccccgccgccgccgccgccgccggttggc
cctgccgcggccgaggagccgctgcaccgaccaaagaaagagctctcagccaccaagaaa
gaccgcgtgaaccactgtctgacaatctgtgaaaacatcgtcgcgcagtctctcagaaat
tctccagaatttcagaaacttctgggcatcgctatggaactttttctgctgtgcagtgat
gacgcagagtcagatgtcaggatggtggctgacgaatgcctcaacaaagtcataaaagct
ttgatggactctaatcttccgaggttgcagctagaactctacaaggaaattaaaaagaac
ggcgccccgcggagcctgcgcgcggccctctggaggttcgccgagctggctcacctggtc
cggcctcagaagtgcaggccgtacctggtgaacctgttgccctgcctgacgcgcacaagc
aagagacccgaggagtccgtccaggagacgctggctgcagcgatccctaaaattatggct
tcttttggcaactttgcgaacgacaatgagattaaggttctgttgaaggctttcatcgcg
aacctgaagtccagttccccgactgtgcggcggaccgcggcgggctcagtggtcagcatc
tgccagcactccaggaggacgcagtacttttacagctggctgctcagcgtgctcctaggt
ttgctggtccccgtggaggaggagcaccccaccctgctgatcctcggcgtcctgctcgcg
ctgaggtccttggtgccgctgctgcagcagcaggtcaaggacacgagcctgaaaggcagc
ttcggggtgacgcggaaagagacggaggtctctccctcgacggagcagctcgtccaggtg
tacgagctgaccttgcactacacccaacaccaggaccacaacgtcgtgaccggggccctg
gagctgctgcagcagctcctccgaaccccgccgcccgagctcctgcgcgcgctgaccacg
gcgggcggcgtccggcagctcgcggccgccaaagacgagcccgggggccgcagtcggagc
gggagcatcgtcgagctgatagctggagggggttcttcatgcagccctgtcctttcaaga
aaacaaaaagggaaagtgctcttcggagaagcggcacccttggaagatgactcggagtcc
aggtcggagggcagcagccccgccttctcagcctcagccaagggtgaggccggaggtgag
ctggctgcctcttccggggtctccacccctggctccaccagctcggcggccgactctgcg
ggtcacggcatcatcaccgagcagccccggtcacagcacacgcgtcagacggactcggtg
gatctggccgcctgtgacctgacaagcgccgccaccgacggggacgaggaggacatcctg
agccgcagctccagccagatgagcgccgtcccttccgaccccgccatggacctgaacgac
gggacccaggcctcctcgcccatcagcgacagctcccagaccaccaccgaggggcccgat
tcagccgtgaccccttccgacagttctgaaattgtgttagatggccctgacagccagtat
ccggggatgccggcggggcagatgcaggacgaggacggggacgctaccgccgttcttcct
gacgacgcagaggctttcagaaactcttccatcgcccttcaacaagcacatttgttgaaa
agcatgggccacagcaggcaggcctccgacagcagtgtggataaatttgtctcaagagag
gaagctgccgaaccaggggatccagagagcaagccctggcgggtcaaaggcgacattggc
cagtccactgacgaggattccgcccctcttgtccattgcgtccgccttttgtccgcttcg
tttctgctcacaggggaaaagaatgccttggttccggacagggacgtgcgggtcagcgtg
aaggcgctggccctcagctgcgttggagccgccgtggcccttcatcctgagtctttcttc
agcaaactctacagagcgcctcttgacaccgtggaattccctgaggagcagtacgtgtca
gacgtcttgaactacatcgaccacggggacccgcaggtccggggagccacagccatcctg
tgcgggaccctcgtctgctccgtcctcggccggtgccgcttccatgtggcgggctggatg
ggcgccgtcagagcccggacaggaaatacattttctctggcggactgcattcccctgctg
cagaaaactttgaaggacgaatcctcggttacttgcaagttggcttgtgctgctgtgagg
ctctgtgtcatgagcctctgcagcagcagctacagtgcgtgggggctgcagctcatcacc
gacctgctggccctgcggagcagctcctactggctggtgcggacggagcttctggagacg
gtggcagagatcgacttcaggttggtgagctttctggaggccaaagcagaaagcctgcac
agaggggcccatcactatacagggcgtttaaagctgcaagagcgggtactcagtaatgtt
gtcatccatctgcttggagatgaagaccccagggtgcgacacgttgctgcagcttcgttg
atgaggctcgtcccaaagctgttttacaagtgcgaccgaggacaggcggacccggtggtg
gtcgtggcgcgagaccagagcagcgtgtacctggcgctcctcatgcacgagccgcagcct
ccgtcccacctctccgtcagcgccgcaaccagaatttatagaggctataacctgctacca
agcatcacagatgtcactctggaaaacaacctctcgagagtcatcgcagcggtttcgcat
gaactgatcatgtccaccacgagggcactcacatttggatgctgcgaagctctgtgtctg
ctgtcaactgccttcccagtttgcatctggagtttaggttggcactgtggagtgcccccg
ctgagcgcctccgatgagtccaggaagagctgcaccgtggggatggtcacgatgatcctg
acgctgctctcgtcagcctggttcccgctggatctctctgcccaccaggatgccctgatt
ttagcggggaacttgctggcagccagcgcccccaggtctccgcggagctcgtgggcctct
gaagacgaggccagcacggcagccagcaaacaggaggaggcgtggccggccctgggtgac
cggaccctggtgcccatggtggagcagctcttctcccacctgctgaaggtcatcaacatc
tgtgcgcacgtcctggacgacgtggctccgggacccgcagtgaaggcagccctgccttct
ctcacaaacccgccttctctgagcccaatccgaaggaaggggaaagagaaggagccggga
gagcaggcgtctgtgcccgtgagtcccaagaaaggcggcgagtccagtccagcctctcga
ccacctgaaacctcagggcctgttgccacaaacaagtcctcgtcactggggagcttctgt
cacctgccttcttacctcaaactgcacgacgtcctgaaagccactcacgccaactacaag
gtcaccttggatcttcagagcagcagcgagaaggttgggggtttcctgcgctctgccttg
gacgttttgtctcagattttggagctggcgacgctgcaggacattgggaagtgtgttgaa
gagatcctgggatacctgaagtcttgcttcagtcgagagccaatgatggcaaccgtgtgt
gttcagcagttgctgaagactctgttcgggacaaacctggcctcccagttggatggcctg
tcttcgcatgccagcaagtcgcagggccgtgcgcagcgcctcggctcctccagcgcacgg
cccggcttgtaccactactgcttcatggcgccgtacaccctcttcacccaggccttagcg
gacgccagcctgcggaacgcggcacaggcagagcaggaccaggacaccgcagggtggttt
gacgtcctccagaaagtgtcgacccagctgaagacaaacctcaccagtgtctcaaagaac
cgagcagacaagaatgctattcacaatcacattcgcttgttcgagcctctcgtcataaaa
gcactgaagcagtacacgaccacgacctccgtgcggctgcagaagcaggtgctggccttg
ctggcgcagctagtccagctgcgggtcaactactgcctgctggactcagaccaggtgttc
attggatttgtgctgaagcagtttgaatacattgaagtcggccagttcagggagtcagag
gcgattatcccaaacatctttttcttcctggtattactgtcttacgagcgttaccactca
aaacagatcatcgggatccccaaaatcatccagctctgtgacggcatcatggccagcggg
aggaaggcggtgacgcacgccatacctgccctgcagcccatagtccatgacctcttcgtt
ttaagaggaaccaataaggctgatgcaggaagagagcttgagacccagaaggaggtggtg
gtgtccatgctgctgagactcatccagtaccatcaggtgctggagatgttcacgctggtc
ctgcggcagtgccacaaggagagcgaggacaggtggaagcggctgtcccggcaggtggcc
gacgtcatcctcccgatgctggccaagcagcaggtgcacattgattctcacgaggccctg
ggagtgctgaacacgttgtttgagattttggccccctcctccctgcgccccgtggacatg
cttttacggagtatgttcgtcaccccagacaccctggcggtggtgagcacggtccagctg
tgggtatcaggcatcctggccatcctgcgggtgctgatttcccagtcgaccgaggacatc
gtcctgtcccgcatccaggagctctccttctctccgaacttggtctcctgttcgacaatc
agtaggttgagagatggggacagtgcttcagccccggaggagctcagcgaagggagacag
acgaagaatctgccagaagaaacgtttgccaggtttctgctccaactggttggcatcctt
ttagaggacatcgtcacaaagcagctgagggtggaggtgagcgagcagcagcacaccttc
tactgccaggagctgggcacgctgctcatgtgtctcatccacatcttcaagtcggggacg
ttccggaggatcactgccgctgcctcgaggctcctgagggacggtgcggacggcggcttc
tacagcctggagagcctgaacgcgcgggtgcgctccgtgatccccacgcacccggccctg
gtgctgctctggtgtcagatcctactgctcgtcggccacaccgactaccgctggtgggcg
gaggtgcagcagacgcccaaaagacgcagcctgtccagcacgaagtcgctgagtccggag
acgtctggagaggacgaggatcccgacgtggcttccaagctggggatgtgcaatagagag
atcgtgcggagaggcgccctcattctcttctgcgactacgtctgccagaacctgcatgat
tcggagcacctgacgtggctcatcgtgaaccacattcaagacctgatcagcctgtcccac
gagccccccgtgcaggacttcatcagcgccgtccatcggaactccgccgccagtggcctt
ttcatccaggcgattcagtctcgctgtgagaacctctccactcccaccatgctgaagaga
actctccagtgcctggaagggatccacctgagccagtcgggtgccgtcctgacgctgtac
gtggacaagcttttgtgcacgccgctccgtgcactggctcgtgtggtcgaaacccttgct
tgtcgccgggtggaaatgcttttggccgcaaatttacagagcagcacggcccagctgccg
gcggaggagctgatccggatccaggaacacctgcagagcagcgggttagcacagagacac
cagaggctctactccctgctggacaggcttcgtcttgccaccgcaccggggtcgcacggc
cccacgccccccgtcacgtcccaccccctggacggggatgggcccctggcactggaggca
gtgaatcctgacaaagactggtacgtgcagctggtgcaggcccagtgctggactcggtca
gactctgccctgctggaaggcgcagagctggtgagccggatccccgcgggcgacctgggc
gccttcgtgatgcactcggagttcaacctgagcctgttggcgccgtgcctgggcctgggc
atgcgtgagatctcagggggccagcggagccccctttttgaagcagctcgcatggcgact
ctggaccgcgtgaccgttgtggtccagcagcttcctgctgtccaccaagctttccagccg
ttcctgcccccacagcccgccacctactggagcaagctggatgacctctttggggatgct
gcgctgtatcggactctgaccaccctggcccgggccctggcccagtacctgctggtgttc
tccaggctgcccagccatttgcaacttcctcctgagaaggaaagggacaccgtgaagttt
gtggtcatgaccctcgaggcgctgtcgtggcatctgacccacgcacgggtcccgctgagc
ctagacctgcaggcgggcctggactgctgctgcctggccctgcagctgcccggcctctgg
agcctgctggccgcgcccaacatggtgacccacgcctgctccctcatccactgtgtgcgg
ttcatcctggaggccattgtggtgcagcccggggaccagcttcttagtccagaaagcagg
acgagcgcccccaggtctgccagagaggacggcgtggactcagacacacagacccctcag
tacatcgctgcagcctgtggcatggtggccgagatggtggagtgcctgccgtcggtgttg
gccttgggccacaagaggaacagccacacgcccgcgttcctcacaccggtgctcaggaac
atcatcataagcttggcccgcctgcccctcgtcaacagctacacgcgtgtcccgcccctg
gtatggaaactcggatggtcacccaaaccgggcggggatttcggcacagtgttccctgag
atccccgtggagttcctccaggagaaggaggtctttaaagagttcatctaccgcatcaac
acgctggggtggaccagccgcacccagtttgaggagacatgggccaccctcctcggcgtc
ctggtgactcagccactcgtgatggagcaggaggagagcccccaggaagaggatgtggag
aggacgcagatccacgtcctggccgtgcaggccatcacctccttggtgctgagcgcgatg
accgtgcccgtggccggcaacccggccgtgagctgcctggagcagcagccccggaacaag
cccctgaaggccctcgacaccaggtttggaaggaagctgagtgtcatcagagggattgtc
gagcaggagatccaggcaatggtttccaggagagaaaacgccgccactcaccacctgtac
caggcgtgggaccccgtcccgtctctagccccagccaccacaggtgctctcatcagccat
gacaagctgctgctgcagctcaaccctgagcgtgagctgggggacatgagctacaagctt
ggccaggtgtccatccactcggtgtggctggggaacagcatcacgcccttgcgagaggag
gagtgggacgaggaggaggaggaggccgaggccccagcaccgtcgtccccgcccacgtct
ccgctcaactccaggaaacaccgggctggagtcgatatccactcctgttcgcagtttttg
ctcgagttgtacagtcgctggatcctgccatcgagttccgccaggaggacccccgtcacc
ctgatcagcgaggtggtgcgctcgctcctcgtggtctcggacttgttcacggagcgcaac
cagtttgagatgatgtacctgacgctgacggagttgcggaaggcacacccctcggaagac
gagatcctcctccagtacctggtgcctgccacctgcaaggcggccgccgtcctcgggatg
gacaaggccgtggcggaaccagtcagccggctgctggagagcgcgctccggagcagccac
ctgcccagcacgatgggcgccctgcacggcgtcctgtatgtgctggagtgcgacctcctg
gatgacacggccaagcagctcatccccgtcgtcagcgactacctcctctccagcctccag
ggcagagcccactgcgtgaacgtgcatagccagcagcacgtgctggtgatgtgtgccacg
gccttctacctgatcgagaactacccgctggacgtggggccggagttctcggcctccatc
atacagatgtgtggggtgatgctgtctggaagcgaggaggccaccccgtccgtcgtctac
cactgtgtcctgcggggcttggagcgcctcctgctctccgagcagctctcccggctggac
gcagagtccctggtcaagctgagcgtggaccgggtgaacgtgcacagcccgcaccgcgct
atggcggccctgggcctcatgctcacctgcatgtacacaggaaaggagaaagtcagtcca
ggccgagcgtctgagcccagccctgctgcccctgacagcgagtccgtgatcgtggccatg
gaacgcgtgtccgtcctctttgacaggatccggaaggggttcccctgcgaagcccgcgtg
gtggcccgcgtcctccctcagttcctggacgacttcttcccgccccaggacgtcatgaac
aaggtcatcggcgagttcctgtccagccagcagccgtacccgcagctcatggccactgtc
gtgtaccaggtgttccaagcgctgcacagcgcggggcagtcgtccacggtgcgggactgg
gtcatgctgtcgctctccaacttcacgcagcggagcccggtcgctatggccacgtggagc
ctctcctgcttcttcgtcagcgcgtccaccagcccgtgggtctcggcgatcctcccacac
gtcgtgagcaggatgggcaagctggagcaggtggacgtgaacctcttctgcctggtggct
gcagacttctaccgacaccagatagaggaggagctcgaccgtagggccttccagtctgtg
ttcgaggtggtcgccgtgcccggaaacccataccaccacctgctggcttgtctgcggagc
gtccacaaggccgccacatgctga
DBGET
integrated database retrieval system
