KEGG   Ovis aries (sheep): 100294595
Entry
100294595         CDS       T03117                                 
Symbol
SOCS3
Name
(RefSeq) suppressor of cytokine signaling 3
  KO
K04696  suppressor of cytokine signaling 3
Organism
oas  Ovis aries (sheep)
Pathway
oas04120  Ubiquitin mediated proteolysis
oas04380  Osteoclast differentiation
oas04630  JAK-STAT signaling pathway
oas04668  TNF signaling pathway
oas04910  Insulin signaling pathway
oas04917  Prolactin signaling pathway
oas04920  Adipocytokine signaling pathway
oas04930  Type II diabetes mellitus
oas04931  Insulin resistance
oas04932  Non-alcoholic fatty liver disease
oas04935  Growth hormone synthesis, secretion and action
oas05160  Hepatitis C
oas05164  Influenza A
oas05168  Herpes simplex virus 1 infection
Brite
KEGG Orthology (KO) [BR:oas00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04120 Ubiquitin mediated proteolysis
    100294595 (SOCS3)
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    100294595 (SOCS3)
   04668 TNF signaling pathway
    100294595 (SOCS3)
 09150 Organismal Systems
  09152 Endocrine system
   04910 Insulin signaling pathway
    100294595 (SOCS3)
   04920 Adipocytokine signaling pathway
    100294595 (SOCS3)
   04917 Prolactin signaling pathway
    100294595 (SOCS3)
   04935 Growth hormone synthesis, secretion and action
    100294595 (SOCS3)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    100294595 (SOCS3)
 09160 Human Diseases
  09172 Infectious disease: viral
   05160 Hepatitis C
    100294595 (SOCS3)
   05164 Influenza A
    100294595 (SOCS3)
   05168 Herpes simplex virus 1 infection
    100294595 (SOCS3)
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    100294595 (SOCS3)
   04932 Non-alcoholic fatty liver disease
    100294595 (SOCS3)
   04931 Insulin resistance
    100294595 (SOCS3)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04121 Ubiquitin system [BR:oas04121]
    100294595 (SOCS3)
Ubiquitin system [BR:oas04121]
 Ubiquitin ligases (E3)
  Multi subunit type E3
   Cul5 complex
    Target recognizing subunit
     100294595 (SOCS3)
SSDB
Motif
Pfam: SH2 SOCS_box
Other DBs
NCBI-GeneID: 100294595
NCBI-ProteinID: XP_027830001
LinkDB
Position
11:53174343..53178040
AA seq 229 aa
MVTHSKFPAAGMSRPLDASLRLKTFSSKSEYQLVVNAVRKLQESGFYWSTVTGGEANLLL
SAEPAGTFLIRDSSDQRHFFTLSVKTQSGTKNLRIQCEGGSFSLQSDPRSTQPVPRFDCV
LKLVHHYMPAAGAPSFSPPPAEPSSSPSSEVPEQPPAQPLPGSPPRRAYYIYSGGEKIPL
VLSRPLSSNVATLQHLCRKTVNGHLDSYEKVTQLPGPIREFLDQYDAPL
NT seq 690 nt   +upstreamnt  +downstreamnt
atggtcacccacagcaagttccccgccgccgggatgagccgccccctggacgccagcctg
cgcctcaagaccttcagctccaagagcgagtaccagctggtggtgaacgcagtgcgcaag
ctgcaggagagcggcttttactggagcaccgtgacgggcggcgaagcgaacttgctgctg
agcgccgagcccgcggggaccttcctcatccgcgacagctcggaccagcgccacttcttc
accctcagcgtcaagacccagtcggggaccaagaacctgcgcatccagtgcgaggggggc
agcttctctctgcagagcgacccccggagcacgcagcccgtgccccgcttcgactgcgtg
ctcaagctggtgcatcactacatgcccgccgccggcgccccctcgttctccccgcccccc
gctgaaccctcctcctcgccctcctccgaggtgcccgagcagccaccggcccagccgctc
cccgggagcccccccaggagagcctattacatttactcggggggcgagaagatccctctg
gtgttgagccggcccctctcctccaacgtggccactctccaacatctctgtcggaagacc
gtcaacggccacctggactcctacgagaaagtcacgcagctgcctgggcccattcgggag
ttcctggaccagtacgatgccccgctttag

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