KEGG   Ovis aries (sheep): 100302078
Entry
100302078         CDS       T03117                                 
Symbol
RHOA
Name
(RefSeq) transforming protein RhoA
  KO
K04513  Ras homolog gene family, member A
Organism
oas  Ovis aries (sheep)
Pathway
oas04014  Ras signaling pathway
oas04015  Rap1 signaling pathway
oas04022  cGMP-PKG signaling pathway
oas04024  cAMP signaling pathway
oas04062  Chemokine signaling pathway
oas04071  Sphingolipid signaling pathway
oas04072  Phospholipase D signaling pathway
oas04081  Hormone signaling
oas04144  Endocytosis
oas04150  mTOR signaling pathway
oas04270  Vascular smooth muscle contraction
oas04310  Wnt signaling pathway
oas04350  TGF-beta signaling pathway
oas04360  Axon guidance
oas04510  Focal adhesion
oas04520  Adherens junction
oas04530  Tight junction
oas04611  Platelet activation
oas04621  NOD-like receptor signaling pathway
oas04625  C-type lectin receptor signaling pathway
oas04660  T cell receptor signaling pathway
oas04670  Leukocyte transendothelial migration
oas04722  Neurotrophin signaling pathway
oas04810  Regulation of actin cytoskeleton
oas04921  Oxytocin signaling pathway
oas04928  Parathyroid hormone synthesis, secretion and action
oas04972  Pancreatic secretion
oas05100  Bacterial invasion of epithelial cells
oas05132  Salmonella infection
oas05133  Pertussis
oas05135  Yersinia infection
oas05152  Tuberculosis
oas05163  Human cytomegalovirus infection
oas05200  Pathways in cancer
oas05203  Viral carcinogenesis
oas05205  Proteoglycans in cancer
oas05206  MicroRNAs in cancer
oas05210  Colorectal cancer
oas05417  Lipid and atherosclerosis
oas05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:oas00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04014 Ras signaling pathway
    100302078 (RHOA)
   04015 Rap1 signaling pathway
    100302078 (RHOA)
   04310 Wnt signaling pathway
    100302078 (RHOA)
   04350 TGF-beta signaling pathway
    100302078 (RHOA)
   04072 Phospholipase D signaling pathway
    100302078 (RHOA)
   04071 Sphingolipid signaling pathway
    100302078 (RHOA)
   04024 cAMP signaling pathway
    100302078 (RHOA)
   04022 cGMP-PKG signaling pathway
    100302078 (RHOA)
   04150 mTOR signaling pathway
    100302078 (RHOA)
  09133 Signaling molecules and interaction
   04081 Hormone signaling
    100302078 (RHOA)
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    100302078 (RHOA)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    100302078 (RHOA)
   04520 Adherens junction
    100302078 (RHOA)
   04530 Tight junction
    100302078 (RHOA)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    100302078 (RHOA)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    100302078 (RHOA)
   04621 NOD-like receptor signaling pathway
    100302078 (RHOA)
   04625 C-type lectin receptor signaling pathway
    100302078 (RHOA)
   04660 T cell receptor signaling pathway
    100302078 (RHOA)
   04670 Leukocyte transendothelial migration
    100302078 (RHOA)
   04062 Chemokine signaling pathway
    100302078 (RHOA)
  09152 Endocrine system
   04921 Oxytocin signaling pathway
    100302078 (RHOA)
   04928 Parathyroid hormone synthesis, secretion and action
    100302078 (RHOA)
  09153 Circulatory system
   04270 Vascular smooth muscle contraction
    100302078 (RHOA)
  09154 Digestive system
   04972 Pancreatic secretion
    100302078 (RHOA)
  09156 Nervous system
   04722 Neurotrophin signaling pathway
    100302078 (RHOA)
  09158 Development and regeneration
   04360 Axon guidance
    100302078 (RHOA)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100302078 (RHOA)
   05206 MicroRNAs in cancer
    100302078 (RHOA)
   05205 Proteoglycans in cancer
    100302078 (RHOA)
   05203 Viral carcinogenesis
    100302078 (RHOA)
  09162 Cancer: specific types
   05210 Colorectal cancer
    100302078 (RHOA)
  09172 Infectious disease: viral
   05163 Human cytomegalovirus infection
    100302078 (RHOA)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    100302078 (RHOA)
   05135 Yersinia infection
    100302078 (RHOA)
   05133 Pertussis
    100302078 (RHOA)
   05152 Tuberculosis
    100302078 (RHOA)
   05100 Bacterial invasion of epithelial cells
    100302078 (RHOA)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    100302078 (RHOA)
   05418 Fluid shear stress and atherosclerosis
    100302078 (RHOA)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:oas04131]
    100302078 (RHOA)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:oas04147]
    100302078 (RHOA)
   04031 GTP-binding proteins [BR:oas04031]
    100302078 (RHOA)
Membrane trafficking [BR:oas04131]
 Endocytosis
  Lipid raft mediated endocytosis
   RhoA-dependent endocytosis
    100302078 (RHOA)
Exosome [BR:oas04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   100302078 (RHOA)
  Exosomal proteins of other body fluids (saliva and urine)
   100302078 (RHOA)
  Exosomal proteins of colorectal cancer cells
   100302078 (RHOA)
  Exosomal proteins of bladder cancer cells
   100302078 (RHOA)
GTP-binding proteins [BR:oas04031]
 Small (monomeric) G-proteins
  Rho Family
   RhoA/B/C [OT]
    100302078 (RHOA)
SSDB
Motif
Pfam: Ras Roc Arf GTP_EFTU Gtr1_RagA SRPRB VASP_tetra
Other DBs
NCBI-GeneID: 100302078
NCBI-ProteinID: NP_001155347
UniProt: C5IJ99 A0A6P9FQL7
LinkDB
Position
19:50749367..50799711
AA seq 193 aa
MAAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDGKQVELALWDT
AGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKD
LRNDEHTRRELAKMKQEPVKPEEGRDMANRIGAFGYMECSAKTKDGVREVFEMATRAALQ
ARRGKKKSGCLVL
NT seq 582 nt   +upstreamnt  +downstreamnt
atggctgccatccggaagaaactggtgattgttggagatggagcctgtggcaagacttgc
ttgctcattgtctttagcaaggaccagttcccagaggtgtatgtccctacggtgtttgag
aactatgtggcagatattgaagtggatggaaagcaggtagagttggctttgtgggacaca
gctgggcaggaagattatgatcgcttgaggcctctctcctacccggataccgacgttata
ctgatgtgtttctccattgacagccctgatagtttagaaaacatcccagaaaaatggact
ccggaagtcaagcatttctgtcccaacgtgcccatcatcctggttgggaacaagaaggat
cttcgaaacgacgagcacacaaggcgggagctggccaagatgaagcaggagccagtaaaa
cccgaagaaggcagagatatggcaaacaggattggtgcttttgggtacatggagtgttca
gcaaagaccaaagatggagtgagggaggtttttgaaatggccacgagagctgctctgcaa
gccagacgtgggaagaaaaaatctgggtgccttgtcttgtga

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