Ovis aries (sheep): 100913161
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Entry
100913161 CDS
T03117
Symbol
HSD17B2
Name
(RefSeq) 17-beta-hydroxysteroid dehydrogenase type 2
KO
K13368
17beta-estradiol 17-dehydrogenase / 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+) [EC:
1.1.1.62
1.1.1.239
]
Organism
oas
Ovis aries (sheep)
Pathway
oas00140
Steroid hormone biosynthesis
oas01100
Metabolic pathways
oas04913
Ovarian steroidogenesis
Module
oas_M00976
C19-Steroid hormone biosynthesis, pregnenolone => testosterone => dihydrotestosterone
Brite
KEGG Orthology (KO) [BR:
oas00001
]
09100 Metabolism
09103 Lipid metabolism
00140 Steroid hormone biosynthesis
100913161 (HSD17B2)
09150 Organismal Systems
09152 Endocrine system
04913 Ovarian steroidogenesis
100913161 (HSD17B2)
Enzymes [BR:
oas01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.62 17beta-estradiol 17-dehydrogenase
100913161 (HSD17B2)
1.1.1.239 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+)
100913161 (HSD17B2)
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Motif
Pfam:
adh_short
adh_short_C2
KR
Motif
Other DBs
NCBI-GeneID:
100913161
NCBI-ProteinID:
NP_001254811
UniProt:
I1W6S6
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Position
14:8096021..8195156
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AA seq
388 aa
AA seq
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MGTFFSEPGWLCLTVTAVLGGTILCKLKTSPGQVGRKVVCLAGLWGGACLISLSLFWGLV
LFSLSYFIMYTYFSGQELLPVDQKAVLITGCDSGFGHGLAKYLDELGFTVFAGVLDEQGS
GAEELRRTCSKHLSVLQLNITNTQEIQEAYSKVKEKVQNKGLWAVINNAGVLGLPTDGEL
IPMTEYKRCMAVNFFGAVEVTKAFLPLLRKSKGRLVNISSMAGGVPMQKMAAYGSSKAAL
IMFSSILRQELSKWGVKVSVIQPGGFKTNISGTSQMWETLERTVLDNLSLEVQEDYGQDY
ILSERSLLRLMKTCTDPDISPVLLDVRHAISAQSPFAFYAPGKLSYPWLCFASFSPTGIF
DYLSRKIHSYDKKMPRVLSTSNWENEAM
NT seq
1167 nt
NT seq
+upstream
nt +downstream
nt
atgggcactttcttctctgagccagggtggctctgcctgactgtcaccgcagtgctggga
ggaacaattctttgcaaactcaagacgagcccagggcaggtggggagaaaggtggtctgc
ctggcgggcctctggggaggcgcttgcctgatcagcctgtccctcttctggggcttggtt
ctcttctccctgtcgtatttcatcatgtatacttacttttctggccaagagttgttacct
gtggatcaaaaggcggtgctgataacaggttgcgattctgggtttggccatggtttggcc
aagtatctggacgagctgggcttcactgtatttgccggagttctggatgaacaggggtcc
ggagcagaggaattacgaagaacctgctccaagcatctctctgtgctccagctgaacatc
accaacacgcaggagatacaagaggcctacagcaaagtgaaggagaaggtgcagaacaaa
ggactgtgggctgtgatcaacaacgctggagtccttggcttaccaaccgatggggaactc
attcccatgaccgaatacaaacgatgcatggccgtgaacttcttcggggccgtggaagtc
acgaaggcatttctgcctcttcttagaaaatccaaggggaggctggtgaacatcagcagc
atggcaggaggggttccaatgcagaagatggcagcttatggctcatccaaggcagctctg
atcatgttttcatcaatccttcgacaagagctgtccaaatggggagttaaagtctctgtc
atccagcccggaggcttcaaaacaaacatctcaggcacgagtcaaatgtgggagacgctg
gagagaactgtcctggacaacctttcccttgaagtgcaagaggactacggccaggactat
atccttagcgaacgtagtcttctcaggttaatgaaaacctgcactgatccggacatctcc
ccagtgctcctggacgttcggcatgccatctctgctcagagcccctttgcattttatgcg
ccggggaaattgtcttatccatggctctgttttgcttccttcagccctactggcatattt
gattatcttagcagaaaaatacatagctacgataagaagatgccaagagtattaagcaca
tctaactgggagaatgaggctatgtag
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