Ovis aries (sheep): 101102843
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Entry
101102843 CDS
T03117
Symbol
IDH2
Name
(RefSeq) isocitrate dehydrogenase [NADP], mitochondrial
KO
K00031
isocitrate dehydrogenase [EC:
1.1.1.42
]
Organism
oas
Ovis aries (sheep)
Pathway
oas00020
Citrate cycle (TCA cycle)
oas00480
Glutathione metabolism
oas01100
Metabolic pathways
oas01200
Carbon metabolism
oas01210
2-Oxocarboxylic acid metabolism
oas01230
Biosynthesis of amino acids
oas04146
Peroxisome
oas05230
Central carbon metabolism in cancer
Module
oas_M00009
Citrate cycle (TCA cycle, Krebs cycle)
oas_M00010
Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate
Brite
KEGG Orthology (KO) [BR:
oas00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
101102843 (IDH2)
09106 Metabolism of other amino acids
00480 Glutathione metabolism
101102843 (IDH2)
09140 Cellular Processes
09141 Transport and catabolism
04146 Peroxisome
101102843 (IDH2)
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
101102843 (IDH2)
Enzymes [BR:
oas01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.42 isocitrate dehydrogenase (NADP+)
101102843 (IDH2)
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GFIT
Motif
Pfam:
Iso_dh
Motif
Other DBs
NCBI-GeneID:
101102843
NCBI-ProteinID:
XP_004018103
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Position
18:complement(20799735..20816927)
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AA seq
452 aa
AA seq
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MAGYLRVVRSLCRASGSGSAWAPAALTAPNLQEQPRRHYADKRIKVAKPVVEMDGDEMTR
IIWQFIKEKLILPHVDVQLKYFDLGLPNRDQTNDQVTIDSALATQKYSVAVKCATITPDE
ARVEEFKLKKMWKSPNGTIRNILGGTVFREPIICKNIPRLVPGWTKPITIGRHAHGDQYK
ATDFVVDRAGTFKVVFTPKDGSGPKEWEVYNFPAGGVGMGMYNTDESISGFAHSCFQYAI
QKKWPLYMSTKNTILKAYDGRFKDIFQAIFEKHYKTEFDRHKIWYEHRLIDDMVAQVLKS
SGGFVWACKNYDGDVQSDILAQGFGSLGLMTSVLVCPDGKTIEAEAAHGTVTRHYREHQK
GRPTSTNPIASIFAWTRGLEHRGKLDGNQDLIRFAQTLEKVCVETVESGAMTKDLAGCIH
GLSNVKLNEHFLNTSDFLDTIKSNLDKALGQQ
NT seq
1359 nt
NT seq
+upstream
nt +downstream
nt
atggctggttacctgcgggtcgtacgctcgctctgcagagcctctggctccgggtcggcc
tgggcgccagcagccttgacagcccccaacttgcaagagcagccgcggcgccactatgcc
gacaaaaggatcaaggtggcgaagccagtggtggagatggacggcgatgagatgacccgt
attatctggcagttcatcaaggagaagctcatcctgccccacgtggacgtccagctcaag
tattttgacttggggctcccgaaccgtgaccagaccaatgatcaggtcaccatcgactct
gcgctggccacccagaagtacagcgtggctgtgaagtgtgccaccatcacccccgacgag
gcccgtgtggaagagttcaagctgaagaagatgtggaagagccccaatggaaccatccgg
aacatcctcgggggaactgtcttccgggagcccatcatctgtaagaacatcccgcgtctc
gtccctggctggaccaagcccatcaccattggcaggcatgcccacggcgaccagtacaag
gccacagactttgtggttgaccgggctggcacattcaaggtggtgttcaccccgaaggat
ggcagtggccctaaggaatgggaggtgtacaactttcctgctggtggcgtgggcatgggc
atgtacaacacggatgagtccatctcaggttttgcacacagctgcttccagtatgccatc
cagaagaagtggcctctctacatgagcaccaagaacaccatcctgaaagcctacgacggg
cgcttcaaggacatcttccaggccatctttgagaagcactacaagaccgagttcgacaga
cataagatctggtacgagcaccggctcattgatgacatggtggctcaggtcctcaagtct
tcgggcggctttgtgtgggcctgcaagaactatgacggagacgtgcagtcggacatcctg
gcccagggctttggctcccttggtctgatgacgtccgtgctggtctgcccggatgggaag
accattgaagctgaggctgctcatggcacagtcacccgccactatcgggagcaccagaag
ggccgaccgaccagcaccaaccccatcgccagcatctttgcctggacgcgtggcctagaa
caccggggcaagttggacgggaaccaggacctcatcaggttcgcccagaccctggagaag
gtgtgtgtcgagacagtggagagtggagctatgaccaaggacctggcgggctgcatccac
ggcctcagcaacgtgaagctgaacgaacacttcctgaacacctcggacttcctggacacc
atcaagagcaacctggacaaagctctgggccagcagtag
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