Ovis aries (sheep): 101104108
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Entry
101104108 CDS
T03117
Symbol
NDUFS2
Name
(RefSeq) NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial
KO
K03935
NADH dehydrogenase (ubiquinone) Fe-S protein 2 [EC:
7.1.1.2
]
Organism
oas
Ovis aries (sheep)
Pathway
oas00190
Oxidative phosphorylation
oas01100
Metabolic pathways
oas04714
Thermogenesis
oas04723
Retrograde endocannabinoid signaling
oas04932
Non-alcoholic fatty liver disease
oas05010
Alzheimer disease
oas05012
Parkinson disease
oas05014
Amyotrophic lateral sclerosis
oas05016
Huntington disease
oas05020
Prion disease
oas05022
Pathways of neurodegeneration - multiple diseases
oas05208
Chemical carcinogenesis - reactive oxygen species
oas05415
Diabetic cardiomyopathy
Module
oas_M00143
NADH dehydrogenase (ubiquinone) Fe-S protein/flavoprotein complex, mitochondria
Brite
KEGG Orthology (KO) [BR:
oas00001
]
09100 Metabolism
09102 Energy metabolism
00190 Oxidative phosphorylation
101104108 (NDUFS2)
09150 Organismal Systems
09156 Nervous system
04723 Retrograde endocannabinoid signaling
101104108 (NDUFS2)
09159 Environmental adaptation
04714 Thermogenesis
101104108 (NDUFS2)
09160 Human Diseases
09161 Cancer: overview
05208 Chemical carcinogenesis - reactive oxygen species
101104108 (NDUFS2)
09164 Neurodegenerative disease
05010 Alzheimer disease
101104108 (NDUFS2)
05012 Parkinson disease
101104108 (NDUFS2)
05014 Amyotrophic lateral sclerosis
101104108 (NDUFS2)
05016 Huntington disease
101104108 (NDUFS2)
05020 Prion disease
101104108 (NDUFS2)
05022 Pathways of neurodegeneration - multiple diseases
101104108 (NDUFS2)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
101104108 (NDUFS2)
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
101104108 (NDUFS2)
Enzymes [BR:
oas01000
]
7. Translocases
7.1 Catalysing the translocation of protons
7.1.1 Linked to oxidoreductase reactions
7.1.1.2 NADH:ubiquinone reductase (H+-translocating)
101104108 (NDUFS2)
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Paralog
Gene cluster
GFIT
Motif
Pfam:
Complex1_49kDa
NiFeSe_Hases
Motif
Other DBs
NCBI-GeneID:
101104108
NCBI-ProteinID:
XP_004002740
UniProt:
A0A6P3DZ89
Structure
PDB
PDBj
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All DBs
Position
1:112643586..112652541
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AA seq
463 aa
AA seq
DB search
MAALRALRRLRGAAAQVLRPGAGARLPIQPSRGARQWQPDVEWAEQYGGAVMYPTKETAH
WKPPPWNDVDPPKDTLVSNLTLNFGPQHPAAHGVLRLVMELSGEMVRKCDPHIGLLHRGT
EKLIEYKTYLQALPYFDRLDYVSMMCNEQAYSLAVEKLLNIQPPPRAQWIRVLFGEITRL
LNHIMAVTTHALDIGAMTPFFWMFEEREKMFEFYERVSGARMHAAYVRPGGVHQDLPLGL
MDDIYEFSKNFSLRIDELEEMLTNNRIWRNRTVDIGVVTAEDALNYGFSGVMLRGSGIQW
DLRKTQPYDVYDQVEFDVPIGSRGDCYDRYLCRVEEMRQSIRIISQCLNKMPPGEIKVDD
AKVSPPKRAEMKTSMESLIHHFKLYTEGYQVPPGATYTAIEAPKGEFGVYLVSDGSSRPY
RCKIKAPGFAHLAGLDKMSKGHMLADVVAIIGTQDIVFGEVDR
NT seq
1392 nt
NT seq
+upstream
nt +downstream
nt
atggcggcgctcagggctctgcgccgcctgcgaggcgccgcggcccaggtgctgcggccc
ggggctggggcccgactgccgattcagcccagcagaggtgctcggcagtggcagccagat
gtggaatgggcagagcagtatgggggtgctgtaatgtaccccaccaaggaaacagcccac
tggaaacctcccccttggaatgatgtggaccctccaaaggacacactggtgtcgaacctg
accctgaactttgggccccagcacccagcagcccatggagtcctgcggctagtgatggag
ttgagtggggagatggtgcggaagtgcgaccctcacattgggctgctgcaccgaggcact
gagaagctcattgaatacaagacctatctgcaggcccttccatactttgaccggctggac
tatgtatccatgatgtgtaatgaacaggcctattcactggccgtggagaagctgctcaac
atccagcctcctcctcgtgcacagtggatccgagtgctatttggagaaatcacgcgactt
ttgaaccacatcatggctgtgaccacacatgccctagacatcggggctatgacccctttc
ttctggatgtttgaagaaagggagaagatgttcgagttctacgagcgagtgtctggggct
cggatgcatgctgcttacgtccggccaggaggtgtgcaccaggacctaccccttgggctt
atggatgacatttacgagttttctaagaacttttctcttcggattgacgagctggaggag
atgctgaccaacaataggatctggcgaaatcggacagtcgacattggggttgtaacagca
gaagacgcacttaactatggttttagtggggtgatgctccggggctcaggcatccagtgg
gacctgcggaagacccagccctatgatgtctacgaccaggtggagtttgatgtgcctatt
ggctctcgaggggactgctatgatagatacctatgtcgggtggaggagatgcgccagtcc
attcgaatcatctcacagtgtctgaacaagatgcctcctggggagatcaaggtggatgat
gccaaagtgtctccaccaaaacgagcagaaatgaagacgtctatggagtcactgatccat
cactttaagctgtacaccgagggctaccaagttcccccaggagccacatacacggccatt
gaggcgcccaagggagagtttggcgtgtacctggtgtctgatggtagcagccgcccttat
cgatgcaagatcaaggctcctggttttgctcacctggctggtctggacaagatgtctaag
ggacacatgttggcggacgtcgttgccatcataggtacccaggatattgtgtttggagaa
gtagatcggtga
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