Ovis aries (sheep): 101106012
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Entry
101106012 CDS
T03117
Symbol
PDGFRA
Name
(RefSeq) platelet-derived growth factor receptor alpha
KO
K04363
platelet-derived growth factor receptor alpha [EC:
2.7.10.1
]
Organism
oas
Ovis aries (sheep)
Pathway
oas01521
EGFR tyrosine kinase inhibitor resistance
oas04010
MAPK signaling pathway
oas04014
Ras signaling pathway
oas04015
Rap1 signaling pathway
oas04020
Calcium signaling pathway
oas04072
Phospholipase D signaling pathway
oas04144
Endocytosis
oas04151
PI3K-Akt signaling pathway
oas04510
Focal adhesion
oas04540
Gap junction
oas04630
JAK-STAT signaling pathway
oas04810
Regulation of actin cytoskeleton
oas05163
Human cytomegalovirus infection
oas05200
Pathways in cancer
oas05206
MicroRNAs in cancer
oas05214
Glioma
oas05215
Prostate cancer
oas05218
Melanoma
oas05230
Central carbon metabolism in cancer
oas05231
Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
oas00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
101106012 (PDGFRA)
04014 Ras signaling pathway
101106012 (PDGFRA)
04015 Rap1 signaling pathway
101106012 (PDGFRA)
04630 JAK-STAT signaling pathway
101106012 (PDGFRA)
04020 Calcium signaling pathway
101106012 (PDGFRA)
04072 Phospholipase D signaling pathway
101106012 (PDGFRA)
04151 PI3K-Akt signaling pathway
101106012 (PDGFRA)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
101106012 (PDGFRA)
09144 Cellular community - eukaryotes
04510 Focal adhesion
101106012 (PDGFRA)
04540 Gap junction
101106012 (PDGFRA)
09142 Cell motility
04810 Regulation of actin cytoskeleton
101106012 (PDGFRA)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
101106012 (PDGFRA)
05206 MicroRNAs in cancer
101106012 (PDGFRA)
05230 Central carbon metabolism in cancer
101106012 (PDGFRA)
05231 Choline metabolism in cancer
101106012 (PDGFRA)
09162 Cancer: specific types
05214 Glioma
101106012 (PDGFRA)
05218 Melanoma
101106012 (PDGFRA)
05215 Prostate cancer
101106012 (PDGFRA)
09172 Infectious disease: viral
05163 Human cytomegalovirus infection
101106012 (PDGFRA)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
101106012 (PDGFRA)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
oas01001
]
101106012 (PDGFRA)
09183 Protein families: signaling and cellular processes
04090 CD molecules [BR:
oas04090
]
101106012 (PDGFRA)
Enzymes [BR:
oas01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
101106012 (PDGFRA)
Protein kinases [BR:
oas01001
]
Receptor tyrosine kinases (RTK)
PDGFR family [OT]
101106012 (PDGFRA)
CD molecules [BR:
oas04090
]
Proteins
101106012 (PDGFRA)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
Ig_3
I-set
ig
Ig_2
VEGFR-1-like_Ig-like
VEGFR1-3_N_Ig-like
V-set
Herpes_gE
Kinase-like
Motif
Other DBs
NCBI-GeneID:
101106012
NCBI-ProteinID:
XP_004009879
UniProt:
W5QCN4
LinkDB
All DBs
Position
6:70436112..70487328
Genome browser
AA seq
1089 aa
AA seq
DB search
MGTSHWALLVLGCLFTGPSLILCQLSLPSILPNENERVVQLNSSFSLRCFGESEVSWQYP
MSEEEYPDVEIRNEENNSGLFVTVLEVVSASAAHTGLYTCYYNHTQMDENEIEGRHIYIY
VPDPDVAFVPLGMTDSLVIVEDEDSVIIPCRTTDPETPVTLLSSEGVVHASYDSRQGFKG
TFSVGLYICEATVRGKKFQTIPFNVYAYTATSKLDLEMESPKTVYKAGESIVVTCTVFNN
EVVDFQWTYPGQMKGKGITRLEETKFPSIKLVYTLRVPEATVKDSGDYQCAAHQATKEVK
KMRNVTISVHEKGFIEIKPNFNLLEAVNLHEVKHFVVDVQAYPPPKITWLKDNLTLIENL
TEITTDIEKIQEISYRSKLKLIRAKEEDSGHYTVVVQNEDDVKSYTFELLTQVPSSILDL
VDDHHGSNGGQTVRCTAEGTPLPDIEWMVCKDIKKCNNETSWTVLANNVSNIITEVHPRD
RSTVEGQVTFAKVEETIAVRCLAKNLLGVESRELKLVAPTLRSELTVAAAVLVLLVIVII
SLIVLVVIWKQKPRYEIRWRVIESISPDGHEYIYVDPMQLPYDSRWEFPRDGLVLGRILG
SGAFGKVVEGTAYGLSRSQPVMKVAVKMLKPTARSSEKQALMSELKIMTHLGPHLNIVNL
LGACTKSGPIYIITEYCFYGDLVNYLHKNRDSFLSHHPEKPKKELDIFGLNPADESTRSY
VILSFENNGDYMDMKQADTTQYVPMLERKEVSKYSDIQRALYDRPASYKKKSMLDSEVKN
LLSDDNAEGLTLLDLLSFTYQVARGMEFLASKNCVHRDLAARNVLLAQGKIVKICDFGLA
RDIMHDSNYVSKGSTFLPVKWMAPESIFDNLYTTLSDVWSYGILLWEIFSLGGTPYPGMM
VDSTFYNKIKSGYRMAKPDHATSEVYEIMVKCWNSEPEKRPSFYHLSEIVENLLPGQYKK
SYEKIHLDFLKSDHPAVARMRVDSDNAYIGVTYKNEEDKLKDWEGGLDEQRLSADSGYII
PLPDIDPVPEEEDLGKRNRHSSQTSEESAIETGSSSSTFIKREDETIEDIDMMDDIGIDS
SDLVEDSFL
NT seq
3270 nt
NT seq
+upstream
nt +downstream
nt
atggggacttcccattgggcactcctggtcttaggctgtctcttcacagggccgagccta
atcctctgccagctttcattaccctccatcctgcccaatgaaaatgagagggttgtgcag
ctgaattcatccttttctctgagatgctttggggagagtgaagtgagctggcagtacccc
atgtctgaagaagagtaccccgacgtggaaatcagaaacgaggagaacaacagtggcctt
tttgtgacggtgctggaagtggtcagcgcctcggcagcccacactgggctgtacacttgc
tattacaaccacacgcagatggacgagaacgagatcgagggcagacatatttacatctat
gtgccagacccagatgtagccttcgtacctctaggaatgacagattccttggtcatcgtg
gaggacgaagattcagtcatcatcccatgccgcacaactgatcctgagactccggtgacc
ttactcagcagtgagggggtagtgcatgcctcctatgacagcagacaaggctttaaagga
accttcagtgtcgggctctatatctgtgaggccacagtcagagggaagaagttccagacc
attccattcaatgtttatgcttacacagcaacatcaaaacttgatctggaaatggaatct
cctaagactgtatataaggcaggcgaatcgattgtggtcacctgcaccgtctttaacaac
gaggtggttgactttcaatggacttaccctggacaaatgaaaggcaaaggcatcacgagg
ctggaggaaaccaagttcccgtccatcaagttggtgtacactctgagggttcccgaggcc
acagtgaaagacagtggagattaccaatgtgctgcccaccaggccaccaaggaggtcaaa
aagatgaggaacgtcaccatttctgttcacgagaaaggatttattgaaatcaaacccaac
tttaacctgttggaagctgtcaacctgcatgaagtcaagcattttgtggtggatgtgcag
gcctatccccctcccaagataacctggctaaaggacaacctgactctgattgagaatctc
acggagatcaccactgacatagagaagattcaggaaataagttatcgaagcaaattaaag
ctgatccgagcaaaggaagaagacagtggccattatactgttgtagttcaaaatgaagat
gatgtgaagagctatacttttgaactcttgactcaagttccgtcctccatactggacttg
gttgacgaccaccatggctctaatgggggccagactgtgagatgcacagccgaagggacc
cctcttcctgatatcgagtggatggtttgcaaggatattaagaaatgtaacaacgaaact
tcatggacggttttggccaacaacgtttcaaacatcatcacagaggtccacccccgagac
aggagcacagtggaaggccaggtgacatttgccaaagtggaggagaccattgcagtccgg
tgtctggccaagaacctcctcggggtggaaagccgagagctgaagctggtggctcccact
ctgcgctctgagctcactgtggcagctgcagtcctggtgttgttggtgattgtaatcatc
tcgctcattgtcctggtcgtcatttggaaacagaaaccaaggtatgaaatccgttggagg
gtcattgaatcaatcagccctgatggacatgaatacatttatgtggacccgatgcagctg
ccttatgactcgagatgggagtttccaagagatggactcgtgcttggtcggatcctgggg
tctggtgcttttgggaaagtggttgaaggaactgcctatggattaagtcggtctcaacct
gtcatgaaagtagcagtgaagatgctaaaacccacagccagatccagtgaaaaacaagct
ctcatgtctgagctgaagataatgacccacctggggccgcatttaaacatcgtgaacttg
ctgggtgcctgcaccaagtcaggccccatttacattatcactgagtactgcttctatggg
gatttggtcaactatttgcataagaatagagacagcttcctgagccaccatccagagaag
ccaaagaaagagctggacatttttggattgaacccggctgacgaaagcacaagaagttat
gttatcttatcttttgaaaacaatggtgactacatggacatgaagcaagctgacactaca
cagtatgtccccatgctggagagaaaagaggtttctaaatactcggacatccagagagcg
ctgtatgatcgcccagcctcgtataagaagaaatccatgttagactcagaagtcaaaaac
ctcctttcagatgataacgcagaaggcctgactttgttggatttgttgagctttacctat
caagttgcccgaggaatggagtttttggcttcaaaaaattgtgtccatcgggacctggcg
gctcgcaacgtcctcctggcgcaagggaaaattgtgaagatctgtgactttggcctggcc
agagacatcatgcatgactcgaactatgtgtccaaaggcagtacctttctccctgtgaag
tggatggctcctgagagcatctttgacaacctctacaccacgctgagtgacgtctggtcc
tatggcatcctgctctgggaaatcttttcccttggtggcacaccctaccctggcatgatg
gtggattctacattctacaataagatcaagagtggataccggatggccaagcctgaccat
gccaccagtgaagtctacgagatcatggtgaagtgctggaacagtgagccggagaagaga
ccctccttttaccacctgagtgagattgtggagaatctgctgcctggacaatataaaaag
agctatgaaaagatccacctggactttctgaagagtgaccaccccgctgtggcacgcatg
cgcgtggactccgacaacgcctacattggcgtcacctacaaaaatgaagaagacaagctg
aaggactgggagggtggcctcgacgagcagaggctgagtgcagatagcggctacatcatc
cctctgcccgacatcgaccctgttcctgaggaggaggacctgggcaagaggaacagacac
agctcacagacctctgaagagagtgccattgagacaggttccagcagttctaccttcatc
aagagagaggatgagaccatcgaggacatcgacatgatggacgacattggcatagactcc
tcggatctggtggaggacagcttcctgtaa
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