KEGG   Ovis aries (sheep): 101108785
Entry
101108785         CDS       T03117                                 
Symbol
PRKACB
Name
(RefSeq) cAMP-dependent protein kinase catalytic subunit beta isoform X1
  KO
K04345  protein kinase A [EC:2.7.11.11]
Organism
oas  Ovis aries (sheep)
Pathway
oas01522  Endocrine resistance
oas04010  MAPK signaling pathway
oas04014  Ras signaling pathway
oas04020  Calcium signaling pathway
oas04024  cAMP signaling pathway
oas04062  Chemokine signaling pathway
oas04081  Hormone signaling
oas04082  Neuroactive ligand signaling
oas04114  Oocyte meiosis
oas04140  Autophagy - animal
oas04211  Longevity regulating pathway
oas04213  Longevity regulating pathway - multiple species
oas04261  Adrenergic signaling in cardiomyocytes
oas04270  Vascular smooth muscle contraction
oas04310  Wnt signaling pathway
oas04340  Hedgehog signaling pathway
oas04371  Apelin signaling pathway
oas04530  Tight junction
oas04540  Gap junction
oas04611  Platelet activation
oas04713  Circadian entrainment
oas04714  Thermogenesis
oas04720  Long-term potentiation
oas04723  Retrograde endocannabinoid signaling
oas04724  Glutamatergic synapse
oas04725  Cholinergic synapse
oas04726  Serotonergic synapse
oas04727  GABAergic synapse
oas04728  Dopaminergic synapse
oas04740  Olfactory transduction
oas04742  Taste transduction
oas04750  Inflammatory mediator regulation of TRP channels
oas04910  Insulin signaling pathway
oas04911  Insulin secretion
oas04912  GnRH signaling pathway
oas04913  Ovarian steroidogenesis
oas04914  Progesterone-mediated oocyte maturation
oas04915  Estrogen signaling pathway
oas04916  Melanogenesis
oas04918  Thyroid hormone synthesis
oas04919  Thyroid hormone signaling pathway
oas04921  Oxytocin signaling pathway
oas04922  Glucagon signaling pathway
oas04923  Regulation of lipolysis in adipocytes
oas04924  Renin secretion
oas04925  Aldosterone synthesis and secretion
oas04926  Relaxin signaling pathway
oas04927  Cortisol synthesis and secretion
oas04928  Parathyroid hormone synthesis, secretion and action
oas04934  Cushing syndrome
oas04935  Growth hormone synthesis, secretion and action
oas04961  Endocrine and other factor-regulated calcium reabsorption
oas04962  Vasopressin-regulated water reabsorption
oas04970  Salivary secretion
oas04971  Gastric acid secretion
oas04976  Bile secretion
oas05012  Parkinson disease
oas05020  Prion disease
oas05030  Cocaine addiction
oas05031  Amphetamine addiction
oas05032  Morphine addiction
oas05034  Alcoholism
oas05146  Amoebiasis
oas05163  Human cytomegalovirus infection
oas05165  Human papillomavirus infection
oas05166  Human T-cell leukemia virus 1 infection
oas05200  Pathways in cancer
oas05203  Viral carcinogenesis
oas05205  Proteoglycans in cancer
oas05207  Chemical carcinogenesis - receptor activation
oas05414  Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:oas00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    101108785 (PRKACB)
   04014 Ras signaling pathway
    101108785 (PRKACB)
   04310 Wnt signaling pathway
    101108785 (PRKACB)
   04340 Hedgehog signaling pathway
    101108785 (PRKACB)
   04371 Apelin signaling pathway
    101108785 (PRKACB)
   04020 Calcium signaling pathway
    101108785 (PRKACB)
   04024 cAMP signaling pathway
    101108785 (PRKACB)
  09133 Signaling molecules and interaction
   04082 Neuroactive ligand signaling
    101108785 (PRKACB)
   04081 Hormone signaling
    101108785 (PRKACB)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    101108785 (PRKACB)
  09143 Cell growth and death
   04114 Oocyte meiosis
    101108785 (PRKACB)
  09144 Cellular community - eukaryotes
   04530 Tight junction
    101108785 (PRKACB)
   04540 Gap junction
    101108785 (PRKACB)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    101108785 (PRKACB)
   04062 Chemokine signaling pathway
    101108785 (PRKACB)
  09152 Endocrine system
   04911 Insulin secretion
    101108785 (PRKACB)
   04910 Insulin signaling pathway
    101108785 (PRKACB)
   04922 Glucagon signaling pathway
    101108785 (PRKACB)
   04923 Regulation of lipolysis in adipocytes
    101108785 (PRKACB)
   04912 GnRH signaling pathway
    101108785 (PRKACB)
   04913 Ovarian steroidogenesis
    101108785 (PRKACB)
   04915 Estrogen signaling pathway
    101108785 (PRKACB)
   04914 Progesterone-mediated oocyte maturation
    101108785 (PRKACB)
   04921 Oxytocin signaling pathway
    101108785 (PRKACB)
   04926 Relaxin signaling pathway
    101108785 (PRKACB)
   04935 Growth hormone synthesis, secretion and action
    101108785 (PRKACB)
   04918 Thyroid hormone synthesis
    101108785 (PRKACB)
   04919 Thyroid hormone signaling pathway
    101108785 (PRKACB)
   04928 Parathyroid hormone synthesis, secretion and action
    101108785 (PRKACB)
   04916 Melanogenesis
    101108785 (PRKACB)
   04924 Renin secretion
    101108785 (PRKACB)
   04925 Aldosterone synthesis and secretion
    101108785 (PRKACB)
   04927 Cortisol synthesis and secretion
    101108785 (PRKACB)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    101108785 (PRKACB)
   04270 Vascular smooth muscle contraction
    101108785 (PRKACB)
  09154 Digestive system
   04970 Salivary secretion
    101108785 (PRKACB)
   04971 Gastric acid secretion
    101108785 (PRKACB)
   04976 Bile secretion
    101108785 (PRKACB)
  09155 Excretory system
   04962 Vasopressin-regulated water reabsorption
    101108785 (PRKACB)
   04961 Endocrine and other factor-regulated calcium reabsorption
    101108785 (PRKACB)
  09156 Nervous system
   04724 Glutamatergic synapse
    101108785 (PRKACB)
   04727 GABAergic synapse
    101108785 (PRKACB)
   04725 Cholinergic synapse
    101108785 (PRKACB)
   04728 Dopaminergic synapse
    101108785 (PRKACB)
   04726 Serotonergic synapse
    101108785 (PRKACB)
   04720 Long-term potentiation
    101108785 (PRKACB)
   04723 Retrograde endocannabinoid signaling
    101108785 (PRKACB)
  09157 Sensory system
   04740 Olfactory transduction
    101108785 (PRKACB)
   04742 Taste transduction
    101108785 (PRKACB)
   04750 Inflammatory mediator regulation of TRP channels
    101108785 (PRKACB)
  09149 Aging
   04211 Longevity regulating pathway
    101108785 (PRKACB)
   04213 Longevity regulating pathway - multiple species
    101108785 (PRKACB)
  09159 Environmental adaptation
   04713 Circadian entrainment
    101108785 (PRKACB)
   04714 Thermogenesis
    101108785 (PRKACB)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    101108785 (PRKACB)
   05205 Proteoglycans in cancer
    101108785 (PRKACB)
   05207 Chemical carcinogenesis - receptor activation
    101108785 (PRKACB)
   05203 Viral carcinogenesis
    101108785 (PRKACB)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    101108785 (PRKACB)
   05163 Human cytomegalovirus infection
    101108785 (PRKACB)
   05165 Human papillomavirus infection
    101108785 (PRKACB)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    101108785 (PRKACB)
  09164 Neurodegenerative disease
   05012 Parkinson disease
    101108785 (PRKACB)
   05020 Prion disease
    101108785 (PRKACB)
  09165 Substance dependence
   05030 Cocaine addiction
    101108785 (PRKACB)
   05031 Amphetamine addiction
    101108785 (PRKACB)
   05032 Morphine addiction
    101108785 (PRKACB)
   05034 Alcoholism
    101108785 (PRKACB)
  09166 Cardiovascular disease
   05414 Dilated cardiomyopathy
    101108785 (PRKACB)
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    101108785 (PRKACB)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    101108785 (PRKACB)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:oas01001]
    101108785 (PRKACB)
  09182 Protein families: genetic information processing
   03019 Messenger RNA biogenesis [BR:oas03019]
    101108785 (PRKACB)
   03036 Chromosome and associated proteins [BR:oas03036]
    101108785 (PRKACB)
Enzymes [BR:oas01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.11  cAMP-dependent protein kinase
     101108785 (PRKACB)
Protein kinases [BR:oas01001]
 Serine/threonine kinases: AGC group
  PKA family
   101108785 (PRKACB)
Messenger RNA biogenesis [BR:oas03019]
 Eukaryotic type
  mRNA surveillance and transport factors
   mRNA cycle factors
    Common to processing body (P body) and stress granule
     101108785 (PRKACB)
Chromosome and associated proteins [BR:oas03036]
 Eukaryotic type
  Centrosome formation proteins
   Kinases and associated factors
    101108785 (PRKACB)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Kinase-like ABC1 Pkinase_C
Other DBs
NCBI-GeneID: 101108785
NCBI-ProteinID: XP_004002181
UniProt: W5PWH9
LinkDB
Position
1:61100541..61251125
AA seq 397 aa
MAAYREVPCNQYTGTTALQKLEGFASRLFHRHSKGTAHDQKTTLENDSLHFSEHTALWDK
SMKEFLAKAKEDFLKKWENPAPNNAGLEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKI
LDKQKVVKLKQIEHTLNEKRILQAVNFPFLVRLEYAFKDNSNLYMVMEYVPGGEMFSHLR
RIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDHQGYIQVTDFGFAKRVKG
RTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSG
KVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVSDIKTHKWFATTDWIAIYQRKVEAP
FIPKFRGSGDTSNFDDYEEEDIRVSITEKCGKEFCEF
NT seq 1194 nt   +upstreamnt  +downstreamnt
atggcagcttatagagaagtaccctgtaaccaatatacaggtactactgctcttcagaaa
ttggaaggttttgctagccgattatttcatagacactccaaaggtactgcacatgatcag
aaaacaactctggaaaatgacagccttcatttctctgaacatactgccttatgggacaaa
tcaatgaaagagtttctagccaaagccaaagaagactttttaaaaaaatgggaaaatcct
gctccgaataatgctgggctggaagattttgaaaggaaaaaaacccttggaacaggttca
tttggaagagtcatgttggtgaaacacaaagccactgaacagtattatgccatgaagatc
ttagataagcagaaggttgttaaactgaagcaaatagagcatactttgaatgagaaaaga
atattacaggcagtgaattttccttttcttgttcgactggaatatgcatttaaggataat
tctaatttatacatggttatggaatatgttcctggtggtgaaatgttttcacatctaaga
agaattggaaggttcagtgaaccccatgcacggttctatgcagctcagatagtgctaaca
ttcgagtacctccattcactagacctcatctacagagatctaaaacctgaaaatctctta
attgaccaccaaggttatatccaggtcacagactttgggtttgccaaaagagttaaaggc
agaacttggacattatgtggcactccagaatatttggctccagaaataattctcagcaag
ggctacaataaggcagtggattggtgggcattaggagtgttaatctatgaaatggcggct
ggctaccccccattctttgcagaccaaccaattcaaatttatgaaaaaattgtttctgga
aaggttcgattcccttctcacttcagttcagatctcaaggaccttctaaggaacctgctg
caggtagacttaacaaagcggtttggaaatctaaagaatggtgtgagtgatataaaaact
cacaagtggtttgctacaacagattggattgctatttaccagagaaaggttgaagctcca
ttcataccaaagttcagaggctctggagataccagcaactttgatgactatgaagaagaa
gatatccgtgtctctataacagaaaaatgtgggaaggaattttgtgaattttag

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