Ovis aries (sheep): 101109574
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Entry
101109574 CDS
T03117
Symbol
RPS6KB2
Name
(RefSeq) ribosomal protein S6 kinase beta-2
KO
K04688
ribosomal protein S6 kinase beta [EC:
2.7.11.1
]
Organism
oas
Ovis aries (sheep)
Pathway
oas01521
EGFR tyrosine kinase inhibitor resistance
oas01522
Endocrine resistance
oas04012
ErbB signaling pathway
oas04066
HIF-1 signaling pathway
oas04140
Autophagy - animal
oas04150
mTOR signaling pathway
oas04151
PI3K-Akt signaling pathway
oas04152
AMPK signaling pathway
oas04211
Longevity regulating pathway
oas04213
Longevity regulating pathway - multiple species
oas04350
TGF-beta signaling pathway
oas04371
Apelin signaling pathway
oas04666
Fc gamma R-mediated phagosome formation
oas04714
Thermogenesis
oas04910
Insulin signaling pathway
oas04931
Insulin resistance
oas05163
Human cytomegalovirus infection
oas05165
Human papillomavirus infection
oas05170
Human immunodeficiency virus 1 infection
oas05200
Pathways in cancer
oas05205
Proteoglycans in cancer
oas05207
Chemical carcinogenesis - receptor activation
oas05210
Colorectal cancer
oas05212
Pancreatic cancer
oas05221
Acute myeloid leukemia
oas05224
Breast cancer
oas05225
Hepatocellular carcinoma
oas05226
Gastric cancer
oas05231
Choline metabolism in cancer
oas05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:
oas00001
]
09130 Environmental Information Processing
09132 Signal transduction
04012 ErbB signaling pathway
101109574 (RPS6KB2)
04350 TGF-beta signaling pathway
101109574 (RPS6KB2)
04371 Apelin signaling pathway
101109574 (RPS6KB2)
04066 HIF-1 signaling pathway
101109574 (RPS6KB2)
04151 PI3K-Akt signaling pathway
101109574 (RPS6KB2)
04152 AMPK signaling pathway
101109574 (RPS6KB2)
04150 mTOR signaling pathway
101109574 (RPS6KB2)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
101109574 (RPS6KB2)
09150 Organismal Systems
09151 Immune system
04666 Fc gamma R-mediated phagosome formation
101109574 (RPS6KB2)
09152 Endocrine system
04910 Insulin signaling pathway
101109574 (RPS6KB2)
09149 Aging
04211 Longevity regulating pathway
101109574 (RPS6KB2)
04213 Longevity regulating pathway - multiple species
101109574 (RPS6KB2)
09159 Environmental adaptation
04714 Thermogenesis
101109574 (RPS6KB2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
101109574 (RPS6KB2)
05205 Proteoglycans in cancer
101109574 (RPS6KB2)
05207 Chemical carcinogenesis - receptor activation
101109574 (RPS6KB2)
05231 Choline metabolism in cancer
101109574 (RPS6KB2)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
101109574 (RPS6KB2)
09162 Cancer: specific types
05210 Colorectal cancer
101109574 (RPS6KB2)
05212 Pancreatic cancer
101109574 (RPS6KB2)
05225 Hepatocellular carcinoma
101109574 (RPS6KB2)
05226 Gastric cancer
101109574 (RPS6KB2)
05221 Acute myeloid leukemia
101109574 (RPS6KB2)
05224 Breast cancer
101109574 (RPS6KB2)
09172 Infectious disease: viral
05170 Human immunodeficiency virus 1 infection
101109574 (RPS6KB2)
05163 Human cytomegalovirus infection
101109574 (RPS6KB2)
05165 Human papillomavirus infection
101109574 (RPS6KB2)
09167 Endocrine and metabolic disease
04931 Insulin resistance
101109574 (RPS6KB2)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
101109574 (RPS6KB2)
01522 Endocrine resistance
101109574 (RPS6KB2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
oas01001
]
101109574 (RPS6KB2)
Enzymes [BR:
oas01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
101109574 (RPS6KB2)
Protein kinases [BR:
oas01001
]
Serine/threonine kinases: AGC group
RSK family [OT]
101109574 (RPS6KB2)
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
Pkinase_C
Kinase-like
Pkinase_fungal
ABC1
FeoB_C
Seadorna_VP7
Motif
Other DBs
NCBI-GeneID:
101109574
NCBI-ProteinID:
XP_027815894
UniProt:
A0ACI6PDJ2
LinkDB
All DBs
Position
21:41726284..41732478
Genome browser
AA seq
485 aa
AA seq
DB search
MAAVFDLDLETEEGSEGEGEPELSPADACPLAELRPAGLEPVGHYEEVELTESSVNPGPE
RIGPHCFELLRVLGKGNYGKVFQVRKVQGSNLGKIYAMKVLRKAKIVRNAKDTAHTRAER
NILESVKHPFIVELAYAFQTGGKLYLILECLSGGELFTHLEREGIFLEDTACFYLSEITL
ALGHLHSQGIIYRDLKPENIMLNSQGHIKLTDFGLCKESIHEGAVTHTFCGTIEYMAPEI
LVRSGHNRAVDWWSLGALMYDMLTGSPPFTAENRKKTMDKIIRGKLELPPYLTPDARDLV
KKFLKRNPNQRIGGGPGDAADVQRHPFFRHVNWDDLLARRVDPPFRPSLQSEEDVSQFDS
HFTRQTPVDSPDDTTLSESANQAFLGFTYVAPSVLDSIKEAFSFQPKLRSPRRLNSSPRT
PVSPLKFSPFEGFRPSPGPQELVEAPLPPLLPPPPPPPPSSTAPLPIRPPSGTKKSKRGR
GRPGR
NT seq
1458 nt
NT seq
+upstream
nt +downstream
nt
atggctgcggtgtttgacctggacctggagacagaggaaggcagcgaaggcgagggcgag
ccagagctcagccccgcggacgcgtgtcccctcgcggagttgaggccggctggcctggag
cctgtgggacactatgaggaggtggagctgactgagagcagtgtgaacccgggccccgag
cgcatcggtccccactgctttgagctgctgcgtgtgctgggcaaggggaactatggcaag
gtgttccaggtgcgaaaggtacagggcagcaatctgggcaaaatatatgccatgaaagtc
ctgaggaaggccaaaattgtgcgcaacgccaaggacacggcacacacgcgggctgagcgg
aacattctggagtcggtgaagcaccctttcattgtggaactggcctatgccttccagact
ggcggcaaactttacctcatcctcgagtgcctcagtggtggtgagcttttcacgcacctg
gagcgagaaggcatcttcctagaagacacggcctgtttctacctgtcagagatcacactg
gccctgggccatctccactcccaaggcatcatctaccgggacctcaaacctgaaaacatc
atgctcaacagccagggccacattaaactgacggactttggcctctgcaaggagtcgatc
cacgagggcgctgtgacccacaccttctgcggcaccatcgagtacatggcgcctgagatt
ctggtgcgcagtggccacaaccgggcggtggactggtggagcttgggggccctgatgtac
gacatgctcactggatcgccgcccttcactgcagagaaccggaagaaaaccatggacaag
atcatcagagggaagctggagctgcccccctacctcaccccggatgcccgggatctcgtc
aaaaagttcttgaagcggaatcctaaccagcggattggagggggccccggggatgctgct
gatgtgcagaggcaccccttcttccggcacgttaattgggatgacctcctggcccgccgt
gtggacccccctttccggccttccctgcaatcggaggaggacgtgagccagtttgactcc
cacttcacaaggcagacaccagtggacagtccagatgacacaacgctcagtgagagtgcc
aaccaggccttcctgggcttcacgtacgtggcaccctccgtcctagacagcatcaaggag
gccttctccttccagcccaagctgcgctcgcccaggcgcctcaacagcagcccccggacc
cctgtcagccccctgaagttctcgcccttcgaggggttccggcccagccccggcccacag
gagctcgtggaggccccgctacctcctctgctgccaccgccgccaccaccaccgccctcc
agcaccgcccccctccccatccgacccccctcagggaccaaaaagtccaagaggggccgt
gggcgccctgggcgctaa
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