| Entry |
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| Symbol |
ABCC1
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| Name |
(RefSeq) multidrug resistance-associated protein 1 isoform X2
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| KO |
| K05665 | ATP-binding cassette, subfamily C (CFTR/MRP), member 1 [EC:7.6.2.3] |
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| Organism |
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| Pathway |
| oas04977 | Vitamin digestion and absorption |
| oas04981 | Folate transport and metabolism |
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| Brite |
KEGG Orthology (KO) [BR:oas00001]
09130 Environmental Information Processing
09131 Membrane transport
02010 ABC transporters
101110991 (ABCC1)
09132 Signal transduction
04071 Sphingolipid signaling pathway
101110991 (ABCC1)
09150 Organismal Systems
09154 Digestive system
04977 Vitamin digestion and absorption
101110991 (ABCC1)
04981 Folate transport and metabolism
101110991 (ABCC1)
09160 Human Diseases
09161 Cancer: overview
05206 MicroRNAs in cancer
101110991 (ABCC1)
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
101110991 (ABCC1)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
02000 Transporters [BR:oas02000]
101110991 (ABCC1)
Enzymes [BR:oas01000]
7. Translocases
7.6 Catalysing the translocation of other compounds
7.6.2 Linked to the hydrolysis of a nucleoside triphosphate
7.6.2.3 ABC-type glutathione-S-conjugate transporter
101110991 (ABCC1)
Transporters [BR:oas02000]
ABC transporters, eukaryotic type
ABCC (CFTR/MRP) subfamily
ABCC1, 2, 3, 4, 5, 6, 10, 11, 12, 13 subgroups
101110991 (ABCC1)
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| SSDB |
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| Motif |
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| Other DBs |
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| LinkDB |
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| Position |
24:14820085..14975573
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| AA seq |
1530 aa
MALRDFCSVDGSDTFWEWNVTWNTSNPDFTKCFQNTVLVWVPCSYLWVCFPFYFLYLSHH
DRGYIQMTHLNKAKTALGFLLWIVCWADLFYSFWERSMGKLLAPVFLVSPTLLGITMLLA
TFLIQIERRRGVQSSGIMLTFWLIALLCALAILRSKIMTALKEDAQADVFRDATFYIYFG
LVLIQLVLSCFSDRSPLFSETINDPNPCPESSASFLSRITFWWITGMMVQGYRQPLESTD
LWSLNKEDTSEQVVPVLVKNWKKECAKSRKQPVKIVYSSKDPAKSKGSSKVDVNEEAEAL
IVKCPQKERDPSLFKVLYKTFGPYFLMSFLFKAVHDLMMFAGPEILKLLINFVNDKKAPE
WQGYFYTALLFISACLQTLVLHQYFHICFVSGMRIKTAVIGAVYRKALVITNAARKSSTV
GEIVNLMSVDAQRFMDLATYINMIWSAPLQVILALYLLWLNLGPSVLAGVAVMVLMVPLN
AVMAMKTKTYQVAHMKSKDNRIKLMNEILNGIKVLKLYAWELAFKDKVLAIRQEELKVLK
KSAYLAAVGTFTWVCTPFLVALSTFAVYVTVDENNILDAQKAFVSLALFNILRFPLNILP
MVISSIVQASVSLKRLRVFLSHEDLDPDSIQRRPIKDAGATNSITVKNATFTWARNDPPT
LHGITFSVPEGSLVAVVGQVGCGKSSLLSALLAEMDKVEGHVTVKGSVAYVPQQAWIQNI
SLRENILFGRQLQERYYKAVIEACALLPDLEILPSGDRTEIGEKGVNLSGGQKQRVSLAR
AVYCDSDVYLLDDPLSAVDAHVGKHIFENVVGPKGLLKNKTRLLVTHGISYLPQMDVIIV
MSGGKISEMGSYQELLARDGAFAEFLRTYASAEQEQGQPDDGLAGVGGPGKEVKQMENGM
LVTDTAGKQMQRQLSNSSSYSGDVSRHHTSTAELQKPGPTEETWKLVEADKAQTGQVKLS
VYWDYMKAIGLFISFLSIFLFLCNHVASLASNYWLSLWTDDPIINGTQEHTKVRLSVYGA
LGISQGITVFGYSMAVSIGGIFASRRLHLDLLHNVLRSPISFFERTPSGNLVNRFSKELD
TVDSMIPQVIKMFMGSLFNVIGACIIILLATPMAAVIIPPLGLIYFFVQRFYVASSRQLK
RLESVSRSPVYSHFNETLLGVSVIRAFEEQERFIRQSDLKVDENQKAYYPSIVANRWLAV
RLECVGNCIVLFASLFAVISRHSLSAGLVGLSVSYSLQVTAYLNWLVRMSSEMETNIVAV
ERLKEYSETEKEAPWQIQDMAPPSDWPQVGRVEFRDYGLRYREDLDLVLKNINVTIDGGE
KVGIVGRTGAGKSSLTLGLFRIKESAEGEIIIDDVNIAKIGLHDLRFKITIIPQDPVLFS
GSLRMNLDPFSQYSDEEVWTSLELAHLKGFVSALPDKLNHECAEGGENLSVGQRQLVCLA
RALLRKTKILVLDEATAAVDLETDDLIQSTIRTQFDDCTVLTIAHRLNTIMDYTRVIVLD
KGEIREWGSPSDLLQRRGLFYSMAKDAGLV |
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| NT seq |
4593 nt +upstreamnt +downstreamnt
atggcgctccgggacttctgcagcgtcgatggctccgacaccttctgggagtggaatgtc
acgtggaacaccagcaaccccgacttcaccaagtgctttcagaacaccgtcctcgtgtgg
gtgccttgctcttacctctgggtctgcttccccttctacttcctctatctctcccaccat
gaccggggctacattcagatgacgcatctcaacaaagccaagactgccttgggatttttg
ctatggatcgtctgctgggcagacctcttctactctttctgggaaagaagtatgggcaag
ctcctggccccagtgttcctggtcagcccaaccctcttgggcatcaccatgctgcttgct
acctttttaattcagatcgagagaaggaggggagtccagtcctcagggatcatgctcact
ttctggcttatagccctactgtgtgcccttgccatcctgagatccaaaatcatgactgcc
ttaaaagaggatgcccaagctgatgtctttcgcgacgccaccttctacatttactttggc
ctcgtgctgatccagctcgtgttgtcctgcttctccgaccgctcgcccctgttctccgaa
accatcaacgaccccaatccttgcccggaatccagtgcctccttcctttccaggatcacc
ttctggtggatcacagggatgatggttcagggctaccgccagcccctggagagcaccgac
ctctggtccctgaataaggaggacacgtcagaacaagtcgtgccggtcttggtaaagaac
tggaagaaggaatgtgccaagtccagaaagcagccggtgaagatcgtgtactcctccaag
gaccccgccaagtccaaagggagctccaaggtggatgtgaacgaggaggccgaggctctg
attgtcaagtgcccccagaaggagcgggacccgtccctgttcaaggtgttatacaagacc
tttgggccctacttcctcatgagcttcttgttcaaggctgtgcatgacctgatgatgttt
gctggcccggagatcttaaagttgctcatcaacttcgtgaacgacaagaaggccccggaa
tggcagggttacttctacacggcgctgctgttcatcagcgcctgcctgcagaccctggtg
ctgcaccagtacttccacatctgcttcgtcagcggcatgcgcatcaagacggccgtcatc
ggggccgtgtaccggaaggccctggtgatcaccaatgccgccagaaagtcctccacggtc
ggggagatcgtcaacctcatgtccgtggacgcccagaggttcatggacctggccacgtac
attaacatgatctggtcagcccctctgcaagtcatccttgccctctacctcctgtggctg
aacctgggcccctccgtcctggcaggggtggccgtgatggtcctcatggtccccctcaat
gctgtgatggccatgaagaccaagacctaccaggtggcccacatgaagagcaaggacaat
cggattaagctgatgaatgaaattctcaatgggatcaaagtgctgaagctttatgcctgg
gagctggcattcaaagacaaggtgctggccatccggcaggaagagctgaaggtgctgaag
aaatctgcctacctggccgccgtggggaccttcacctgggtctgcacccctttcctggtg
gccctgtctacatttgccgtctatgtgaccgtcgacgagaacaatatcctggatgcccag
aaggccttcgtgtccttggccttgttcaacatcctccgcttccccctgaatatcctcccc
atggtcatcagcagcattgtgcaggcgagcgtctccctgaagcgcctgagggtcttcctg
tcccatgaggacctggaccctgacagcatccagcgccggcccatcaaagacgctggagcc
acgaacagcatcactgtgaagaacgccacattcacgtgggccaggaatgacccccccacg
ctgcatggcatcacgttctctgttccggaaggttccctggtggccgtggtgggccaggtg
ggctgtgggaaatcatctctactctcagcgctcttggccgagatggacaaggtggaggga
cacgtgactgtcaagggctcagtggcctacgtcccacagcaggcctggattcagaacatt
tctctccgagaaaacatcctttttggacgccagctacaggaacggtattataaagctgtg
atagaagcctgtgccctcctcccagacctggaaatcctgcctagtggggaccggacagag
attggtgagaagggtgtgaacctgtctgggggccagaagcagcgtgtgagcctggcgcgg
gctgtgtactgcgactctgatgtctacctcctcgacgatcccctctcggctgtggacgcc
cacgtgggcaagcacatctttgaaaacgtggttggccccaaggggcttctgaagaacaag
acgcggctcctggtcacgcatggcatcagctacttgccccagatggatgttatcatagtc
atgagtggcggcaagatctccgagatgggctcctaccaggagctactggctcgggacggt
gccttcgccgagttcctgcgtacctacgccagcgccgagcaggagcaggggcagccggac
gacggcttggcaggcgtcggcggtccagggaaggaggtgaaacagatggagaacggcatg
ctggtgacggacactgcagggaagcaaatgcagaggcagctcagcaactcctcctcctac
agcggggatgtgagccggcatcacaccagcaccgccgagctgcagaagcccgggcccaca
gaggagacctggaagctcgtggaggcggacaaggctcagacggggcaggtcaagctctcc
gtatactgggactacatgaaggcgattggacttttcatctcctttctgagcatcttcctt
ttcctgtgtaaccacgtggcttccctggcctctaactattggctcagtctctggacggat
gaccccatcatcaacgggacccaggagcacacgaaagtccggctgagtgtctatggagcc
ctgggcatttcacaaggtatcacggtgttcggctactccatggcggtgtccatcgggggc
atcttcgcctcccgccgcctgcacctggacctactgcataacgtcctccggtcgcccata
agcttcttcgagcggacccccagcgggaacctggtgaaccgcttctccaaggagctggac
acggtggactcgatgatcccgcaggtcatcaagatgttcatgggctccctgttcaacgtc
atcggcgcctgcatcatcatcctgctggccacgcccatggctgccgtcatcatcccgccc
ctgggcctcatctacttctttgtgcagaggttctacgtggcctcctcccggcagctgaag
cgcctcgagtcggtcagccgctcgccggtttattcccacttcaacgagaccttgctgggc
gtcagcgtcatccgcgccttcgaggagcaggagcgcttcatccgccagagcgacctgaag
gtggacgagaaccagaaggcctactaccccagcatcgtggccaacaggtggctggccgtg
cggctggagtgtgtgggcaactgcatcgtcctgttcgcctccctgtttgccgtgatctcc
cggcacagcctcagtgcgggcttggtgggcctctcggtgtcttactccctgcaggtcacc
gcatacttgaactggctcgttcggatgtcgtccgagatggagaccaacattgtggccgtg
gagagactcaaggaatattcggaaactgagaaggaggctccctggcaaatccaggatatg
gcaccgcccagcgactggccccaggtgggccgagtggagttccgggattatggcctgcgg
taccgagaggacctggacttggttctgaagaacatcaacgtcaccatcgatggcggggag
aaggttggcatcgtggggcggacaggagccgggaagtcgtccctaaccctgggcttgttt
cggatcaaagagtcagccgagggagagataatcattgatgacgtcaacatcgccaagata
ggcctgcacgacctccgcttcaagatcaccatcatcccccaggaccctgttttgttttcg
ggttccctccgcatgaacctggacccattcagccagtactcggatgaagaggtctggacg
tccctggagcttgcccacctgaagggcttcgtgtcagctcttcctgacaaactgaaccac
gagtgcgcagaaggcggggagaacctcagcgttgggcagcgccagcttgtgtgcctggcc
cgggccctgctgaggaagacaaagatcctcgtgttggacgaggccacggcggccgtggac
ctggaaacggacgacctcattcagtccaccatccggacgcaatttgatgactgtaccgtc
ctcaccatcgctcaccggctcaacaccatcatggactacacgagggtgatcgtcctggac
aaaggagagatccgggaatggggctccccctccgacctcctgcagcggagaggtctcttt
tacagcatggccaaagatgctggcttggtgtga |
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