Ovis aries (sheep): 101113739
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Entry
101113739 CDS
T03117
Symbol
SETX
Name
(RefSeq) probable helicase senataxin isoform X1
KO
K10706
ATP-dependent RNA/DNA helicase, senataxin [EC:
5.6.2.5
5.6.2.3
]
Organism
oas
Ovis aries (sheep)
Pathway
oas05014
Amyotrophic lateral sclerosis
Brite
KEGG Orthology (KO) [BR:
oas00001
]
09160 Human Diseases
09164 Neurodegenerative disease
05014 Amyotrophic lateral sclerosis
101113739 (SETX)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03021 Transcription machinery [BR:
oas03021
]
101113739 (SETX)
Enzymes [BR:
oas01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.2 Enzymes altering nucleic acid conformation
5.6.2.3 DNA 5'-3' helicase
101113739 (SETX)
5.6.2.5 RNA 5'-3' helicase
101113739 (SETX)
Transcription machinery [BR:
oas03021
]
Eukaryotic type
RNA polymerase II system
Other transcription-related factors
Transcription termination factor
101113739 (SETX)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
AAA_11
AAA_12
AAA_19
UvrD-helicase
AAA_30
AAA_22
ResIII
nSTAND3
NAT10_TcmA_helicase
SLFN-g3_helicase
AAA_16
UvrD_C_2
Motif
Other DBs
NCBI-GeneID:
101113739
NCBI-ProteinID:
XP_042103958
LinkDB
All DBs
Position
3:4509466..4606648
Genome browser
AA seq
2683 aa
AA seq
DB search
MVPSSKNADEINKTAFQKKCRMSTCCWCTPGGTSTTDFLQRYASKTRSSEFQTADEDLCY
CLECVAEYHKARDELPFLHEVLWELETLRLINHFERSMKAEIGDDDELYIVDNNGEAQLF
DFTGQDFENKLRVPLLEILKYPYLLLHEHVNELCVEALCRMEQANCSFQVFDKHPGIYLF
LVHPNEMVRRWAILTARNLGKVDRDDYYDLQEVLTCLFKVIELGLLENPDIYTSSVLEKG
KLVLLPSHMYDTANYKNYWLGICMLLTILEEQAMDSLLLGSDKQNDFMQSILHTMERQSN
DDSVDPFWPALHCFMVILDRLGSKVWGQLIDPIEAFQTIINNVSYNREIQNIRNSSMRTK
LEPESYLDDMVTCSQIVYNYNPEKTKKDSGWRSAICPDYCPNMYEEMETLANVLQSDIGQ
DMRVHNSTFLWFIPFVQSLMDLKDLGVAYIVEVIHHLYSEVKDVLNQTDAVCDKVTEFFL
LILVSVIELHRNKKCLHLLWVSSQQWVEAVVKCAKLPTTAFARSSEKSSGNCSKGTAMIS
SLSLHSMPSNSVQLACVQLIRSLLKEGYQLGQQTLCKRFRDKLNLFLRGNLSLGWQLTSQ
ETHELQTCLKQIIRNIKFKVPQFSTSVDLNPACKTPPASFKEESEQIGKKSEKDVHCLEN
SSPTSSKEPMKADAYQVQESILSKANNAIEETKEPCYIKDLKLEGHLSAESCLKLRSKNL
ACERVQNQVKISTGKYKCVKENSSCTPQDGTLRNGPEKVFDRGIIISRRLLTVSSTDSME
KVSASNEDFSLKDDDLGKSSTAKSKTHKDGVCAKLSHVIKKQHRKSISLEENLTVSGIEG
FYSKKDIGGQKGGGNICTPSLVPNGILDDKNGEQKSQSCLLLRKKEVKKEKLDIFSTPEN
SCQIQECHVDTKDLVSLTEMTNTFMMKASPFKEPVTGHELRDRKISRSTDQFSSNLREQD
LSSSPQPDTLTDSQVDRDLHKLSLMAQASVTKFPSDSTQKSLSQIQRKVKDEKRCFTANQ
NIRETCRGQVIIISDSDEEEEEERILGLKKQMKEIKACIEKECPEQHTSIANTNVEQKVL
IKEENPVSLLQFEESDSQFFEFETPCEVFSVWHDQKPDKNSAQEEEKNPCSTPVGDTAND
LGYETDYVSEEVIKKVAENFEERTKPRSSTSVEEFCEIEVKKPKRRRYENPIAEDPLRPS
SSVKNEDQSGIFNKGNLSKNDFKGVDPRATVPSSSVQRNAAVSPKKSLPKPRTYSRPVRK
VPVVKASKKSPSDTKKGQSKSSHYISCRTTPAIVPPKKFRQCPEPTSTVEKLGLKKAPRR
AFELSQRSLECIDQLRDHGRSVGVVDTRKKTKLISPQTLSVRNNKKLLTSQDLQLHRQMR
SKSQRNRQGRFDYRSTDKTRAGPCAAQSSAVPESSKSDYSHHGGAEVTANNKGKQLLTCQ
SSETEPVKANQCNPVMVNGRTATTEAIVPTSEALLGRGDPTVHHLEVATLKEGEPEFSSD
IEEEDIFLTQRDPEDMDLCSQIEGEYDKLIEVIDGKDTVQGEEECVRQPQSESLSSTKCR
YKDCVETLKNPGEYCSKHSKTKATDEDTFRKPGLPLSASKRLRPSTTKVFSSSSTSRIAG
LSKSLESTASLPSCLKNKSSGAQSVLKGPQPPLLVSLKPVAEVKGLCSVFPAQTPNNSNR
QVLRVPFGESRSFLTSSPVNILTSSQSISDTFVKEVLKWRYEMFVNFDQCGPPSSLCQSI
ARRVPIRFQDCGDYFNVFFPLVVLNTFETVAQEWISSPNKEKFHQLHLRKFPGDYKKYWE
FVVYLEESELAKQLHPRENDLVFLVPERLNEEKKDLEWSHLEDACEYYCGYVHKFRRTSV
MHNGKSECSVSIQTQDNLPVNLNELVKCFVISSLVTTQRKLKAMSLLSGRNQLARAILNP
NPMDFCTKDLLTTTSERIVAYLKDFNEDQKKAIETAYAMVKHSPSVAKICLIHGPPGTGK
SKTIVGILYRLLTENQRRGHSDENSNAKIKQNRVLVCAPSNAAVDELMKKIILEFKEKCK
DKKNPMGNCGDINLVRLGPEKSINNEVLRFSLDSQVNHRMKKDLPSHVQEMHKRKEFLDR
QLDELSRQRALCRGGRESQRQELDGKIARVSKERQELASKIKEVQGRPQKTQSIIILESH
IICCTLSTSGGLLLEAAFRGQGGVPFSCVIVDEAGQSCEVETLTPLIHRCNKLVLVGDPK
QLPPTVISVKAQDYGYDQSMMARFHKLLEESVEHNMIGRLPVLQLTIQYRMHPDICLFPS
SYVYDGALKTNRGTETSRCSSDWPFQPYLVFDVGDGLERRDNDSYVNVQEIKLVMELIKL
IKDKRRDINFRNIGIITHYKAQKTMIQKDLDKEFDRKGAAEVDTVDAFQGRQKDCVIVTC
VRANATQGSIGFLASLQRLNVTITRAKYSLFILGHLRTLVENRHWYHLIQDAQKRGAIIK
TCDKNYRHDAMKILKLKPLLQRSLTHPPAVAPEASRPQGGLPSSKQDGELSKTSFASSLY
HSPSDSKEATVTEAAKDPERPPTQDRLRDPRLLRRMGLAFDAQGISLREPQPLSPQHSGA
APPSGAPGCPGSPQEPCTVRQQGVTLNSHMPHTQCDSPAAGADTSTSKKKCDQEEGVLGH
RRETRALSEGDQEWWASSHTKRNSDWDERGLEEDSHSKKRRVL
NT seq
8052 nt
NT seq
+upstream
nt +downstream
nt
atggttcccagcagtaaaaacgctgatgaaattaacaaaactgccttccagaagaagtgc
agaatgagtacatgttgttggtgtaccccagggggtacttccaccactgacttcctgcaa
cgctatgcatccaagacccgctccagtgaatttcagacagctgatgaagacctctgctac
tgcttggagtgtgtggctgagtaccacaaagcaagggacgaattgccattcttacatgag
gttttatgggaattagaaaccttacgtctcataaatcactttgaaagatccatgaaggca
gaaattggagatgatgatgagttatatatagtagacaacaacggagaggcacagctgttc
gacttcactggccaagactttgaaaataagcttcgagttcctcttcttgaaatactgaaa
tatccatatttgcttttacatgagcatgtcaatgaattatgtgttgaagcactttgccgg
atggaacaagctaattgctcctttcaagtttttgacaaacatccagggatctatttattt
ttggttcatcccaatgaaatggttcggcgttgggctatcctgactgcaagaaacttgggg
aaagtggatagagatgattactatgacttacaggaggttttgacttgcctttttaaagtt
attgagttgggacttttagaaaacccagacatttatacttcttctgtccttgagaagggt
aaactggttcttctgccttcacacatgtatgatactgccaactacaaaaactattggtta
ggtatttgcatgctgcttaccattcttgaggagcaagccatggattcactgttgttgggc
tcagataaacagaatgattttatgcagtcaatacttcataccatggagaggcaatcaaat
gatgatagtgtggatcctttctggccagcattacactgtttcatggtgattctggatcgc
cttggatctaaggtctggggtcaacttattgatcctattgaagcatttcaaaccattatt
aacaacgtgagctacaatagagagatccagaacatacggaacagctctatgaggaccaag
ttagaaccggagtcatatttggatgatatggtgacttgcagccagattgtatacaattat
aatcctgaaaagaccaaaaaggattcggggtggagatcagccatttgccccgattattgt
cctaacatgtatgaagaaatggaaacattagctaacgtgctccagtcagatattggtcag
gacatgcgtgttcataacagcacatttctgtggttcatccctttcgtgcaatccctcatg
gacctgaaggatctgggtgtggcttacatagtggaggttattcaccatctgtactctgaa
gtcaaagatgttctcaaccagacagacgctgtgtgtgacaaagtcactgagtttttcctt
ctgattttggtgtccgtgattgaactgcatagaaataaaaaatgtctacatttgctgtgg
gttagttcccagcagtgggtggaggctgtggtgaagtgtgccaagctaccgaccacagcg
tttgcacggagttccgagaagtcatctggaaactgttccaaaggcacagcaatgatatca
tccctgtcactgcattcaatgccctccaactctgtgcagctggcttgtgtgcagctgatt
agaagtctcctgaaagaaggctatcagcttgggcagcagactctctgtaaacggttccgg
gataaactcaacttattcctgcgagggaatttatctttaggttggcagttgactagtcag
gaaacccatgagctacaaacttgtttaaagcaaattattaggaacataaaattcaaagta
cctcagtttagcacttctgtcgatctgaatcctgcatgtaagacacctccagcatctttt
aaagaagaaagtgaacaaatagggaagaagtctgaaaaagatgtgcactgtctggaaaat
tccagcccaacatcttctaaagaaccaatgaaagctgatgcatatcaagtgcaagagagt
attttgagcaaagcaaataatgctatagaagagactaaagagccgtgttatataaaagat
ttgaaactagaaggccacctctcagctgagtcatgtttgaagctgaggagtaaaaacctt
gcctgtgaaagagttcaaaatcaagttaaaataagtacagggaaatataagtgtgtaaaa
gagaattcctcatgtaccccacaggatggtactttaagaaatggtccagaaaaagtattt
gacagaggaataataatatcaaggcgcttattgactgtttctagtacggattctatggaa
aaagtgtctgcctccaatgaggacttctctttaaaggatgatgatcttggcaaaagctca
acagcaaaatctaagacacataaagatggagtctgtgctaagttgtcacatgtaataaaa
aagcaacacaggaaaagtatcagtttagaggaaaacctgactgtatctggcattgagggt
ttctattcaaagaaagatataggaggtcagaaaggaggtggaaacatatgcactccttct
ttagtccctaatggtattctggatgataaaaatggagaacaaaaatctcaaagctgttta
ttgctgagaaagaaagaagtaaagaaagaaaagttagatattttttctacccctgaaaac
agttgtcaaatacaggaatgtcatgttgataccaaagatttggtctcactcacagaaatg
accaatactttcatgatgaaagcatctccctttaaagagcctgtgactggacatgaattg
agagataggaaaattagtaggagcactgatcaattttcttctaatttaagagaacaggac
cttagcagcagtccccagcctgacaccttaacagattctcaggtagatagagacctccac
aaattatctttaatggctcaagccagtgttactaagttcccatcagattcaactcaaaaa
agtttatcccaaatacaaagaaaagtaaaagatgagaaaagatgtttcacagcaaaccaa
aatatcagggaaacctgccgtggacaggttattattatttcagattccgatgaggaggag
gaggaggaaagaatcctgggtttgaagaaacaaatgaaagagatcaaagcatgcattgag
aaagaatgtccagagcaacatacttcaatagctaacacaaatgtggaacagaaggtatta
ataaaggaagaaaatccagtgtcccttttgcagtttgaggaatctgattctcagtttttt
gagtttgagactccatgtgaagtgttttcagtttggcatgatcagaaaccagacaagaat
tcagctcaagaggaggagaaaaatccatgctcgactcctgtgggtgatactgcaaatgat
ttgggttatgagacagattatgtatctgaagaggtcattaaaaaagtagcagagaacttt
gaagagcgcacaaaaccacgtagtagtacttctgttgaggaattttgtgaaattgaagta
aaaaaacccaagagaagacggtatgaaaaccctatagctgaagatcctctaaggccttca
tcttctgtcaaaaatgaggaccagtctggtatttttaacaaggggaatctgagtaaaaat
gattttaaaggtgtagacccaagagctacagttcccagttcaagtgttcagagaaatgct
gcggtttccccaaagaagtctcttccaaagcctcgcacgtattccagacctgtcaggaaa
gttccagtggttaaagcttctaagaaatccccttcagataccaagaaaggacagagtaaa
agttcccattacataagctgtagaacaactcctgctattgtgccgccaaagaaatttcgc
cagtgtcccgaaccaacttcaacggttgagaaacttggcctgaaaaaggctcctcgtagg
gcgtttgaattgtcccagcgatctttagagtgtatagatcagctacgtgaccatggcaga
tctgttggagtagtcgacacccggaaaaagacaaagttaatttctcctcagactctctct
gtcagaaataataagaaactgctgacgagtcaagaccttcagttgcataggcagatgaga
tccaaatcacaacgcaacagacaaggacgttttgattatcgaagtacagataagacccga
gcagggccatgtgctgcacagagctctgctgtgccggagtcaagtaagtcagattacagt
catcacggaggagccgaagtgactgctaacaataagggaaaacagttactaacatgtcag
tcttctgaaacagaacccgtgaaagcaaaccagtgtaatcctgtcatggtaaatggaaga
acagcaacgactgaagccattgttcctacctcagaggccctgttaggcagaggtgaccca
acagtccatcatttagaggtggcgactttgaaagagggagagcctgaattcagcagtgac
atagaggaggaggatatattcttaacacagcgtgaccctgaagacatggatttatgttca
caaattgagggagagtatgataaactcattgaagtcattgatggaaaagataccgtgcag
ggagaggaagagtgtgtgaggcagcctcagtcggaatctttgagtagcacaaaatgtagg
tacaaagattgtgttgaaactctgaaaaacccaggtgaatactgctctaaacactcaaaa
actaaagccacagatgaagatacatttcgtaaacctggcttgcctctgtctgcatcaaaa
cgtttgagaccttccacgaccaaggtttttagttcaagcagtacttcacggattgctggt
ctctccaagtctttggaaagtaccgcatccctcccatcatgtctgaaaaacaagtcaagt
ggggcacagtctgttctgaaaggaccacagccaccccttctggtgtctctgaagccagtg
gctgaagtgaaaggtctgtgcagtgttttccctgctcagactccaaataactccaacagg
caagttttgagagttccatttggggaaagcagatcttttttgacttcctctccagtaaac
attctcacatcgtcacagtccatctctgatacctttgtaaaagaggtcttgaaatggaga
tacgagatgtttgtgaactttgaccagtgtgggcccccgtcgagtctgtgtcagtccatc
gcaagacgggtgcctatcaggtttcaagactgtggagattatttcaatgtgtttttccct
ttggtggtactgaatactttcgaaacagtggcacaggaatggatcagctctccaaacaaa
gagaaattccatcagttgcatttacgaaaatttcctggtgattataaaaaatactgggag
tttgtggtttatcttgaggaaagtgaactagctaaacagcttcatccaagggaaaatgat
ttggtgtttttggttcctgaaagactcaatgaggagaagaaagatttagagtggagtcac
ctggaggatgcctgtgaatattactgtggctatgttcataaattccgccgtacttcagtc
atgcataatgggaaatctgagtgttcggtttccatccagactcaagataatttaccagtc
aatttaaatgaactcgtgaaatgctttgtaatcagctctctggtgactacacaaaggaag
ttgaaagccatgtctttgctgagtggtcggaaccaactggccagagccattctgaatcca
aaccccatggacttctgtacaaaagatttactaactacaacgtctgagagaattgttgcc
tacttaaaagatttcaatgaagaccagaagaaagcgatagaaactgcatatgccatggtg
aaacactccccatcagttgccaagatctgtctgattcatggaccacctggaacaggaaaa
tcaaaaaccattgttggcatcctgtaccgcctgctgaccgagaaccaaaggagggggcat
tcagatgaaaactccaatgccaaaatcaagcaaaaccgtgtcctcgtatgtgcaccttcc
aatgcagctgttgatgagcttatgaaaaaaattatccttgaattcaaagaaaagtgtaaa
gacaagaagaatcctatgggaaactgtggagatataaacttagtacgtctaggtccagaa
aagtctattaataatgaggtcctaagattcagtttggacagtcaagttaaccacagaatg
aaaaaagacttaccatctcatgttcaggagatgcacaaaagaaaggaatttctcgatcgt
caacttgatgaactttcccgccagcgtgctttatgccgaggtggaagggaatcgcagagg
caagaattagatggaaaaattgccagagtttcaaaagaaaggcaggagcttgcttctaaa
attaaagaggttcaaggacgcccacagaagacacagagcatcatcatcttagagtcgcac
atcatttgctgcacactgagcacgagtggtggcctgctgctcgaggctgctttccgtggg
cagggaggcgtccccttcagctgtgtcatcgttgatgaggctggacagtcctgtgaagtt
gaaactcttactccactcatccatcgttgcaacaagcttgtcctcgtaggagaccctaag
cagctccctcccacagtcatttccgtgaaggcacaggactatggctatgaccagtcaatg
atggcccgcttccacaagctcctggaggagagtgtggagcacaacatgattggcaggctg
cctgtcttacagctcaccatccagtacaggatgcacccggacatatgcctctttccttct
agttatgtttatgacggagccttgaaaacaaatagagggacagagaccagtcggtgctca
tctgactggccatttcaaccctacctcgtgtttgatgttggagatggcttagaaagacgg
gataatgactcatatgtaaatgttcaagagataaaactggtaatggaactaattaaactt
attaaagacaaaagaagggacattaatttccgaaacattggcataataacccattacaag
gctcagaagacgatgattcagaaggatttggacaaagagtttgatagaaaaggggcagca
gaagtagataccgtggatgccttccagggccgtcagaaagactgtgtcattgttacatgc
gtcagagcaaatgccacacagggctcaattggatttctggcaagtttgcagagattgaat
gtcaccatcacacgagccaagtacagcctctttatcctgggacacttgagaaccctagtg
gaaaataggcattggtatcacctgattcaagatgcacagaaacgtggcgccattattaag
acttgcgacaagaactacagacacgatgcaatgaagatcctgaagctcaaaccattgctt
cagaggagccttactcaccctcctgctgtcgctccagaggcatccagaccccagggtggc
ctacccagcagcaagcaagatggtgaactcagcaagacatcttttgcttcttccctgtac
cactcaccctctgattccaaagaagccacagtcactgaggctgcaaaggatcctgaaagg
ccacccactcaggaccggcttcgggacccaagactgctgcggaggatgggcttagccttt
gatgcccaaggaataagcctcagggagccgcagcccttgagcccccagcattctggagca
gcgcctccgtcaggcgcgccaggctgccctgggagtccccaggagccatgcaccgtcagg
cagcagggagtcaccctgaacagccacatgcctcacacgcagtgcgactctccagccgct
ggtgctgacacttccacaagcaaaaagaagtgtgaccaggaagagggggtgctcggccac
aggagagagaccagggccttgagtgaaggggatcaggagtggtgggcgagctcccacaca
aagaggaactcagactgggatgagaggggcctggaggaggacagccactcaaagaagaga
cgggttttatag
DBGET
integrated database retrieval system
