Ovis aries (sheep): 101115088 Help Entry 101115088         CDS       T03117                                  Symbol TSC2 Name (RefSeq) tuberin isoform X1   KO K07207   tuberous sclerosis 2 Organism oas  Ovis aries (sheep) Pathway oas04072   Phospholipase D signaling pathway oas04115   p53 signaling pathway oas04140   Autophagy - animal oas04150   mTOR signaling pathway oas04151   PI3K-Akt signaling pathway oas04152   AMPK signaling pathway oas04211   Longevity regulating pathway oas04218   Cellular senescence oas04714   Thermogenesis oas04910   Insulin signaling pathway oas04919   Thyroid hormone signaling pathway oas05163   Human cytomegalovirus infection oas05165   Human papillomavirus infection oas05168   Herpes simplex virus 1 infection oas05231   Choline metabolism in cancer Brite KEGG Orthology (KO) [BR:oas00001]  09130 Environmental Information Processing   09132 Signal transduction    04072 Phospholipase D signaling pathway     101115088 (TSC2)    04151 PI3K-Akt signaling pathway     101115088 (TSC2)    04152 AMPK signaling pathway     101115088 (TSC2)    04150 mTOR signaling pathway     101115088 (TSC2)  09140 Cellular Processes   09141 Transport and catabolism    04140 Autophagy - animal     101115088 (TSC2)   09143 Cell growth and death    04115 p53 signaling pathway     101115088 (TSC2)    04218 Cellular senescence     101115088 (TSC2)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     101115088 (TSC2)    04919 Thyroid hormone signaling pathway     101115088 (TSC2)   09149 Aging    04211 Longevity regulating pathway     101115088 (TSC2)   09159 Environmental adaptation    04714 Thermogenesis     101115088 (TSC2)  09160 Human Diseases   09161 Cancer: overview    05231 Choline metabolism in cancer     101115088 (TSC2)   09172 Infectious disease: viral    05168 Herpes simplex virus 1 infection     101115088 (TSC2)    05163 Human cytomegalovirus infection     101115088 (TSC2)    05165 Human papillomavirus infection     101115088 (TSC2)  09180 Brite Hierarchies   09181 Protein families: metabolism    01009 Protein phosphatases and associated proteins [BR:oas01009]     101115088 (TSC2) Protein phosphatases and associated proteins [BR:oas01009]  Protein serine/threonine phosphatases   Phosphoprotein phosphatases (PPPs)    Protein phosphatase-1     PP1-interacting proteins (PIPs)      101115088 (TSC2) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Tuberin DUF3384 Rap_GAP Cnd1 Motif Other DBs NCBI-GeneID:  101115088 NCBI-ProteinID:  XP_027817288 LinkDB All DBs Position 24:2116873..2147722 Genome browser AA seq 1815 aa AA seqDB search MAKPTSKDSGLKEKFKILLGLGTPRPNPRSAEGKQTEFIITAEILRELSVECGLNNRIRV IGQICEVARTKKFEEHAVEALWKAVSDLLQPERPPEARHAVLALLKAIVQGQGDRLGVLR ALFFKVIKDYPSNEDLHERLEVFKALTDNGRHITYLEEELADFVLQWMDVGLSSEFLLVL VNLVKFNSCYLDEYIASMVHMVCLLCVQTVSSVDIEVSLQVLDAVVCYNCLPAESLPLFI VTLCRTINVKELCEPCWKLMRNLLGTHLGHSAIHHMCRIMEDRAYMEDAQLLRGAVFFVG MALWGAHRLYSLKNSPTSVLPSFYEAMTCPNEVVSYEIVLSITRLIKKYRRDLQAVTWDI LLNIIERLLQQLQSLDSPELSAIVHDLLSTVEELCDQNEFHGSQERYFELVERCADQRPE SSVLNLITYRAQSIHPAKDGWIHNLQLLMERFFRSESRSAVRIKVLDVLSFVLLINRQFY EEELINSVVISQLSHIPEDRDHQVRKLATQLLVDLAEGCHTHHFNSLLDIIEKVIARSLS PPPELEERDVAAHSASLEDVKTAVLGLLVILQTKLYALPASHATRVYETLVSHIQLHYKH SYTLPIASSIRLQAFDFLLQLRADSLHRLGLPSKDGLVRFSPYCVCDYLETERSSEKKAG GPLSPPAGPPGPAPAGPAARLGSLPYSLLFRVLLQCLKQETDWKVLKLVLSKLPESLRYK VLIFTSPCSVDQLSAALCSMLSGPKTLERLRGTPEGFSRTDLHLAVVPVLTALISYHNYL DKTRQREMVYCLEQGLIYRCASQCVVALAVCSVEMPDVILKALPVLVVKLTHISATASMA IPLLEFLSTLARLPHLYRNFAAEQYASVFAISLPYTNPSKFNQYIVCLAHHVIAMWFIRC RLPFRKDFVPYITKGLRSNVLLSFDDTPEKDSFRARSTSLNERPKSLRIARPPKQGLNNS PPVKELKESSAADAFRCRSISVSEHVVRSRIQTSLTSASLGSADENSMAQADDNLKNLHL ELTETCLDMMARYVFSNFTAVPKRSPVGEFLLAGGRTKTWLVGNKLVTVTTSVGTGTRSL LGLDSGELQGGPELSSDPSVHVRQTKEAPAKLESQAGQQVYHGARDRVRSMSGGHGLRVG ALDAPACHFPGSPTSLGSQTAPAGQPEKASAGSPLPAQKEKTNLAAYVPLLTQGWAEILV RRPTGNTSWLMSLENPLSPFSSDINSMPLQELSNALMAAERFKERRDTALYKSLSVPAAG SAKPSPPPRSNTVASFSSLCQSRCQGKLHRSISWADSAVVLEEGGPGEASLSAEPPELED FEATLGSDGRCGRSDAFSRSSSTSSQEEKSFHAEELPPGGIPIERAVSSEGSRASVDLAF QPSQPLSKSSSSPELQTLQDILGDPGDKAEVGRLSPEAKARSQSGILDGEGAPWSAPGEE RRGRGPAQPEGPLPSSCPRSPSGLRPRGYTISDSAPSRRGKRVERDAFKSRAGTSNTEKV PGINPSFVFLQLYHSPFFGDESNKPILLPNESFERSVQLLDQIPSYDTHKIAVLYVGEGQ SNSELAILSNEHGSYRYTEFLTGLGKLIELKDCQPDKVYLGGLDVCGEDGQFTYCWHDDI MQAVFHIATLMPTKDVDKHRCDKKRHLGNDFVSIVYNDSGEDFKLGTIKGQFNFVHVIIT PLDYECNLVSLQCRKDMEGLVDTSMAKIVSDRNLPFVARQMALHANMASQVHHSRSNPTD IYPSKWIARLRHIKRLRQRIREEAHYSSASLPLMQTHPPGHAKAPAQAPAESTPAYETGQ RKRLVSSVDDFTEFV NT seq 5448 nt NT seq  +upstreamnt  +downstreamnt atggctaagccaacaagcaaagattcaggcttgaaggagaagttcaagattctgttggga ctggggactccacggccaaaccccaggtctgcagagggcaagcagactgagtttatcatc accgcggaaatcctgagagagttgagtgttgaatgtggcctaaataatcgcatccgggtg atagggcagatctgtgaggttgccagaacgaagaaattcgaagagcacgcggtggaagca ctctggaaggccgtctcggacctgctgcagccagagcggccacccgaggcccggcatgcg gtgctggctctgctgaaggccattgtgcagggacagggggaccgcctgggcgttctcagg gccctcttcttcaaggtcatcaaggattacccctctaatgaagacctccacgagagactg gaagttttcaaggccctcacagacaatgggagacacatcacctacttggaagaagagctg gcggactttgtcctgcagtggatggatgttggcctgtcctccgaattcctcctggtgctc gtgaacttagtcaaattcaacagctgttaccttgatgaatacatcgcctccatggtccac atggtctgcctgctctgtgtccagaccgtgtcctccgtggacatagaggtgtctctgcag gtgctggatgctgtggtttgctacaactgtctgccagccgagagcctccccctgttcatc gtcaccctctgccgcaccatcaacgtcaaggagctctgtgaaccttgctggaagctgatg cgcaacctcctgggcacccacctgggccacagcgccatccaccacatgtgccgtatcatg gaagacagagcctacatggaggacgcacagctgctgagaggagctgtgttctttgttggc atggctctctggggtgcccaccggctctattctctcaagaactccccaacatctgtgttg ccatcgttttatgaggccatgacctgtccgaatgaggtggtgtcctatgagattgtcctc tccataaccagacttatcaagaagtacaggagggatctccaggccgtgacctgggacatc ctgctgaacatcatcgagcgcctgctccagcagctccagagcctggacagtccagagctg agcgccatcgtgcacgacctgctgagcacagtggaggagctgtgcgaccagaacgagttt catggctcgcaggagagatactttgagctcgtggagaggtgtgcggaccagaggcctgag tcgtccgtcttaaacttaataacctacagggctcagtccatccatccagcgaaggacggc tggatccacaacctgcagctgctgatggagaggttcttcaggagcgagtcgcgtagcgct gtgcgcatcaaggtgctagacgtgctgtccttcgtgctgctcatcaacaggcagttctat gaggaagagcttatcaactcagtggtcatctcgcagctctcccacatccctgaggataga gaccaccaggtccggaagctggccactcagctgctggtagatctggctgaaggctgccac acccaccacttcaacagcctactggacatcattgagaaagtgatcgcccgctccctctct ccgccccctgagctggaggagagggatgtggccgcgcactcagcctccttggaggatgtg aagactgcagtcctggggctcctggtcatccttcagaccaagctgtatgccctgcccgcc agccatgccacacgtgtgtatgagacgctggtcagccacattcagctccactacaagcac agctacaccctgcccattgccagcagcatccgtctgcaggcctttgacttcctgctgcag ctgcgggccgactcactgcaccgcctgggcctgcccagcaaagacgggctcgtgaggttc agcccctactgcgtctgtgactacctggagacagagaggagctccgagaagaaggccggg gggccgctgtccccgcctgccgggccccctggccccgcacccgcgggccctgccgcgcgc ctcggctccctgccctactccctgctcttccgtgttctgctgcagtgtctgaagcaggag accgactggaaggtgctgaagctggtgctcagcaagctgcccgagtcgctgcgctataag gtcctcatcttcacctccccgtgcagcgtcgaccagctgtccgccgccctctgctccatg ctttcaggtcccaagaccctggagcggctccgaggcaccccagaaggcttctccagaacc gacctgcatcttgctgtggttcccgtgctgacagccctgatctcttatcataactacttg gacaaaactagacagcgggagatggtgtactgcctggagcaaggcctcatctaccgctgt gccagccagtgtgtggtggccctggccgtatgcagcgtggagatgcctgacgtcatcctc aaggcgctgcctgtcctggtcgtgaagctcacacacatctcggccacggccagcatggcc atcccgctcctcgagttcctgtccactctggccaggctgcctcacctctacaggaacttc gcagcagagcagtatgccagcgtgtttgccatctccctgccgtataccaacccctccaag ttcaatcagtatattgtgtgcctggcccatcacgtcatagccatgtggttcatcaggtgc cgcctgcccttccggaaggactttgttccttacatcaccaagggtctgcgctccaacgtc ctcctgtcttttgatgacactcccgagaaggacagcttcagagcgcggagcaccagtctc aacgagaggcccaagagtttgaggatagccagaccccccaaacaaggcttgaataactct ccacccgtgaaagaactcaaggagagctctgcagccgatgccttccggtgccgcagcatc agtgtgtctgaacatgtggtccgcagcaggatccagacctctctcacgagcgccagcttg gggtctgcagatgagaactcgatggcccaggccgacgacaacttgaaaaacctccacctg gagctcacagagacgtgtctggacatgatggccagatacgtgttctccaatttcacggca gtccccaagaggtcccctgtaggagagttcctcttggctggtggcaggaccaaaacctgg ctggttgggaacaagcttgtcaccgtgacgacgagcgtggggaccgggacccggtcactg ctaggcctggactcgggagagctccagggtggcccggagttgagctctgaccccagcgtg cacgtgagacagacaaaggaggcacccgccaagctggagtcccaagctgggcagcaggtg taccacggagcccgggaccgggtccgttccatgtccgggggccatggccttcgcgtgggt gccttggacgctccagcctgccacttccctggcagccccacatccctgggctcccagact gctccagctggccagcccgagaaggcctcagctggcagcccgctcccagcgcagaaggag aagacaaacctggccgcttacgtgcccctgctgacccagggctgggcggagatcctggtc cgcaggcccacagggaacaccagctggctgatgagcctggagaacccgctcagccccttc tcctcggacatcaacagcatgccgctgcaggagctgtccaatgccctcatggctgccgag cgcttcaaggaacgccgcgacacagccctgtacaagtcgctgtcagtgccggcggccggc tcggccaagccatccccgcccccacgctccaacacagtggcctctttctcctccctgtgc cagtccaggtgccaaggaaagctgcacaggagcatttcctgggcagattccgcggtagtc ctggaggagggaggtccaggcgaggccagtttgtctgcagagcctcccgagttggaagac ttcgaggcaacactgggctccgatgggcgctgtgggcgcagcgacgctttcagcaggtca tcttccacctccagccaggaggagaagtcattccacgccgaggagttgcctcctgggggc atccccatcgagcgggcggtctcctcggagggctcccgggcctccgtggacctcgccttc cagccttctcagcccctgagcaagtccagctcgtcgcctgaactgcagaccctgcaggac atcctgggggaccccggggacaaggctgaggttggccggctgagccctgaggccaaggct cggtcgcagtcagggatcctggacggggaaggtgctccctggtcagccccgggtgaggaa cgccggggccggggccccgcccagccagagggccccctgccttccagctgtccccgctcc cccagtgggctgcggccccgaggctacaccatctcggattcggccccgtcacgcaggggc aagagggtggagagggatgccttcaagagccgggcagggacctccaacaccgagaaggtg ccgggcatcaaccccagcttcgtgttcctgcagctctaccactcaccgttcttcggtgac gagtccaacaagccaatccttttgcctaatgagtctttcgaacggtcagtgcagctcctt gaccagatcccgtcatatgacacgcacaagattgcagtcctgtacgtgggagaaggccag agcaatagcgagctcgccatcctgtccaatgagcacggctcctacaggtacacagagttc ctcacagggctgggcaagctcatcgagctcaaggactgtcagccggacaaggtgtacctg ggcggcctggatgtgtgcggcgaggacggccagttcacctactgctggcatgacgacatc atgcaagcggtcttccacatcgccaccctgatgcccaccaaggacgtggacaagcaccgc tgtgacaagaagcgccacctgggcaacgacttcgtgtccatcgtctacaatgactctggc gaggatttcaagttgggcaccatcaagggccagttcaactttgtccacgtgattatcaca cccctggattacgagtgcaacctggtgtctctgcagtgcaggaaagacatggagggcctt gtggacaccagcatggccaagatcgtgtccgaccgaaacctgccctttgtggcccgccag atggccctgcacgcaaacatggcctcgcaggtgcaccatagccgctccaaccccaccgac atctacccctccaagtggattgccaggctccgccacatcaagcggctgcgccagcggatc cgtgaggaagcccactactcaagcgccagcctgcccttgatgcagacacaccctcctggt catgccaaggctccggcacaggccccagccgagtccacgcctgcctatgagacgggccag cggaagcgcctggtctcctctgtggacgatttcactgagttcgtgtga

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