Ovis aries (sheep): 101115152
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Entry
101115152 CDS
T03117
Symbol
PAK4
Name
(RefSeq) serine/threonine-protein kinase PAK 4 isoform X2
KO
K05734
p21-activated kinase 4 [EC:
2.7.11.1
]
Organism
oas
Ovis aries (sheep)
Pathway
oas04012
ErbB signaling pathway
oas04014
Ras signaling pathway
oas04360
Axon guidance
oas04510
Focal adhesion
oas04660
T cell receptor signaling pathway
oas04810
Regulation of actin cytoskeleton
oas05170
Human immunodeficiency virus 1 infection
oas05206
MicroRNAs in cancer
oas05211
Renal cell carcinoma
Brite
KEGG Orthology (KO) [BR:
oas00001
]
09130 Environmental Information Processing
09132 Signal transduction
04012 ErbB signaling pathway
101115152 (PAK4)
04014 Ras signaling pathway
101115152 (PAK4)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
101115152 (PAK4)
09142 Cell motility
04810 Regulation of actin cytoskeleton
101115152 (PAK4)
09150 Organismal Systems
09151 Immune system
04660 T cell receptor signaling pathway
101115152 (PAK4)
09158 Development and regeneration
04360 Axon guidance
101115152 (PAK4)
09160 Human Diseases
09161 Cancer: overview
05206 MicroRNAs in cancer
101115152 (PAK4)
09162 Cancer: specific types
05211 Renal cell carcinoma
101115152 (PAK4)
09172 Infectious disease: viral
05170 Human immunodeficiency virus 1 infection
101115152 (PAK4)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
oas01001
]
101115152 (PAK4)
Enzymes [BR:
oas01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
101115152 (PAK4)
Protein kinases [BR:
oas01001
]
Serine/threonine kinases: STE group
STE20 family
101115152 (PAK4)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
PBD
Kinase-like
ABC1
Pkinase_fungal
hnRNP_Q_AcD
RIO1
KIND
Motif
Other DBs
NCBI-GeneID:
101115152
NCBI-ProteinID:
XP_027834070
LinkDB
All DBs
Position
14:48216468..48264563
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AA seq
593 aa
AA seq
DB search
MFGKKKKRVEISAPSNFEHRVHTGFDQHEQRFTGLPRQWQSLIEESARRPKPLIDPACIT
SIQPGAPKTIVRGSKGAKDGALTLLLDEFENMSVTRSNSLRRDSPPPPARARQENGMPAE
QAATARGAPEKAGSQGRGAGHGEAGGSSGDRRRAGPDKRPKSSREGSGGPQESSRDKRPL
SGPDVGTPHQPASLASGAKVAAGRPFNTYPRADTDHPSRGTQAEPHNMAPNGPSVGGLAI
PQSSSSRPPARAHGAPSPGVLGPHASEPQLAPPARTLTAPAGPPAPGPPGPRSPQREPQR
VSHEQFRAALQLVVDPGDPRSYLDNFIKIGEGSTGIVCIATVRSSGRLVAVKKMDLRKQQ
RRELLFNEVVIMRDYQHENVVEMYNSYLVGDELWVVMEFLEGGALTDIVTHTRMNEEQIA
AVCLAVLQALSVLHAQGVIHRDIKSDSILLTHDGRVKLSDFGFCAQVSKEVPRRKSLVGT
PYWMAPELISRLPYGPEVDIWSLGVMVIEMVDGEPPYFNEPPLKAMKMIRDNLPPRLKNL
HKVSPSLKGFLDRLLVRDPAQRATAAELLKHPFLAKAGPPASIVPLMRQNRTR
NT seq
1782 nt
NT seq
+upstream
nt +downstream
nt
atgttcgggaagaagaagaagcgggtcgagatctctgcgccgtctaacttcgagcaccgc
gtgcacacgggcttcgaccagcatgagcagaggttcacggggctgccccgccaatggcag
agcctgatcgaggagtcggcccgccggcccaagcccctcatcgaccccgcctgcatcacc
tccatccagcctggggcccccaagaccatcgtgcggggcagcaaaggcgccaaggatggg
gccctcacgctgctgctcgacgagttcgagaacatgtcggtgacgcgctccaactccctg
cggagagacagcccgccgccacctgcccgtgcccgccaggaaaacgggatgcccgcggag
caggccgctacggccagaggggccccagagaaggcgggcagccaaggccggggagccggt
catggcgaggcgggtggcagcagtggagacaggcggcgggcggggccggacaagaggccc
aagtcttccagggagggctcgggaggtccccaggagtcctcccgggacaagcgtcccctc
tctgggcctgacgtcggcaccccccaccaacccgccagtctagccagcggggcgaaagtg
gcggctggccggccctttaacacgtacccgcgggccgacacggaccacccgtcccggggc
acccaggcggagcctcacaacatggcccccaacgggccatcggtggggggcctggccatc
ccccagtcctcctcctcccggccccctgcccgagcccatggcgcccccagccctggagtg
ctgggcccccacgcctctgagccccagctggcccccccagcccgcaccctcaccgccccc
gcagggccccctgcccccgggccccccggcccccgctcaccgcagcgggagccccagcga
gtgtcccacgagcagttccgggctgccctgcagctggtggtggaccccggcgacccccgc
tcctacctggacaacttcatcaagattggcgagggctccaccggcatcgtgtgcatcgcg
actgtgcgcagctctggcaggctggtggccgtcaagaagatggacctgcgcaagcagcag
cggcgggagctgctcttcaacgaggtggtgatcatgagggactaccagcatgagaacgtg
gtggagatgtacaacagctacctggtcggggacgagctctgggtggtgatggagttcctg
gagggaggtgccctcaccgacatcgtcacgcacaccaggatgaacgaggagcagatcgct
gctgtgtgcctggccgtgctgcaggccctgtccgtgctccacgcccagggagtcatccac
cgggacatcaagagtgactccatcctgctgacccacgacggcagggtgaagctgtcagac
ttcgggttctgcgcccaggtgagcaaggaggtgcctcggaggaagtccctagtcggcaca
ccctactggatggccccagagctcatctcccgcctgccctatgggccagaggtggacatc
tggtctctgggggtgatggtgatcgagatggtggacggggagcccccttacttcaatgag
ccacccctcaaagccatgaagatgatccgggacaacctgccaccccgactgaagaacctg
cacaaggtgtcaccgtccctgaagggcttcctggaccgcctgctggtgcgtgacccagcc
cagcgggccacagcggccgagctgctcaaacacccgttcctggccaaagcgggcccaccc
gccagcatcgtgcccctcatgcgtcagaaccgcacccgatga
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