Ovis aries (sheep): 101115372
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Entry
101115372 CDS
T03117
Symbol
PLA2G4B
Name
(RefSeq) cytosolic phospholipase A2 beta isoform X1
KO
K16342
cytosolic phospholipase A2 [EC:
3.1.1.4
]
Organism
oas
Ovis aries (sheep)
Pathway
oas00564
Glycerophospholipid metabolism
oas00565
Ether lipid metabolism
oas00590
Arachidonic acid metabolism
oas00591
Linoleic acid metabolism
oas00592
alpha-Linolenic acid metabolism
oas01100
Metabolic pathways
oas04010
MAPK signaling pathway
oas04014
Ras signaling pathway
oas04072
Phospholipase D signaling pathway
oas04217
Necroptosis
oas04270
Vascular smooth muscle contraction
oas04370
VEGF signaling pathway
oas04611
Platelet activation
oas04664
Fc epsilon RI signaling pathway
oas04666
Fc gamma R-mediated phagocytosis
oas04724
Glutamatergic synapse
oas04726
Serotonergic synapse
oas04730
Long-term depression
oas04750
Inflammatory mediator regulation of TRP channels
oas04912
GnRH signaling pathway
oas04913
Ovarian steroidogenesis
oas04921
Oxytocin signaling pathway
oas05231
Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
oas00001
]
09100 Metabolism
09103 Lipid metabolism
00564 Glycerophospholipid metabolism
101115372 (PLA2G4B)
00565 Ether lipid metabolism
101115372 (PLA2G4B)
00590 Arachidonic acid metabolism
101115372 (PLA2G4B)
00591 Linoleic acid metabolism
101115372 (PLA2G4B)
00592 alpha-Linolenic acid metabolism
101115372 (PLA2G4B)
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
101115372 (PLA2G4B)
04014 Ras signaling pathway
101115372 (PLA2G4B)
04370 VEGF signaling pathway
101115372 (PLA2G4B)
04072 Phospholipase D signaling pathway
101115372 (PLA2G4B)
09140 Cellular Processes
09143 Cell growth and death
04217 Necroptosis
101115372 (PLA2G4B)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
101115372 (PLA2G4B)
04664 Fc epsilon RI signaling pathway
101115372 (PLA2G4B)
04666 Fc gamma R-mediated phagocytosis
101115372 (PLA2G4B)
09152 Endocrine system
04912 GnRH signaling pathway
101115372 (PLA2G4B)
04913 Ovarian steroidogenesis
101115372 (PLA2G4B)
04921 Oxytocin signaling pathway
101115372 (PLA2G4B)
09153 Circulatory system
04270 Vascular smooth muscle contraction
101115372 (PLA2G4B)
09156 Nervous system
04724 Glutamatergic synapse
101115372 (PLA2G4B)
04726 Serotonergic synapse
101115372 (PLA2G4B)
04730 Long-term depression
101115372 (PLA2G4B)
09157 Sensory system
04750 Inflammatory mediator regulation of TRP channels
101115372 (PLA2G4B)
09160 Human Diseases
09161 Cancer: overview
05231 Choline metabolism in cancer
101115372 (PLA2G4B)
Enzymes [BR:
oas01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.1 Carboxylic-ester hydrolases
3.1.1.4 phospholipase A2
101115372 (PLA2G4B)
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Gene cluster
GFIT
Motif
Pfam:
PLA2_B
cPLA2_C2
C2
BMF
Motif
Other DBs
NCBI-GeneID:
101115372
NCBI-ProteinID:
XP_012036643
LinkDB
All DBs
Position
7:35444385..35455637
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AA seq
822 aa
AA seq
DB search
MALAKVPGTCLLTIRVLQAHGLPSKDLVTSSDCYVTLWLPTASSHQLQTRTVKNCRNPVW
NQSFHFRIHSQIKVDGRQPWPRSLSPTVASQPLVPCLTPSSCRPLTLFPFQNIVHLRVFD
QDLLTTDDPVLSVLFDVGTLRAGETRRKSFSLSPQGEERLEVEFRLQNLTDGAEYLFSNG
ILVARELSCLHVRLEKAGDFQESEGRVQLVVPGSCEGPQEAFVGAGSFRFHWPACWEQEL
SIHLQDAPQEQLKVPLRALPSGQVVRLVFPTSQEPLMKVELKNEEGSRELAVRLGCGPCA
EEQAFLSRRKQVVAKALQQALQLDGDLREEEIPVVAVMATGGGIRAMTSLYGQLAGLKAL
GLLDCVSYITGASGSTWALANLYEDPEWSQKDLAGPIESLKTQVTKSKLGVLAPRQLLRY
QQELAERARLGHPTCFTNLWALVNEALLHDEPHDYKLSDQREALSRGQNPLPIYCALNTK
EQNLTTFEFGEWCEFSPYEVGFPKYGAFIPPELFGSEFFMGRLTKQLPESRICFLEGIWS
NLYAANLQDSLYWSSEPSQFWDRWAQARASLDKEQVPLLKIEEPPTVAGSIAEVFTDLLT
RRPLAQATHNFLRGFSFHKDYFQHPHFSAWKATKLDGLPNELTPAEPYLCLLDVGYLVNT
SCPPLLPPTRDVDLILSLDYNLHGAFQQLQLLGRFCQEQGIPFPPISPSPEEQCQPQECH
LFSDPARPDIPAVLHFPLVNASFRDHSAPGVRRTAEEQAAGEVNLSESDSPYHYSKVTYS
LEDVDKLLRLTQYNICNNQERLLEALREAMQRRRQRTQRRPE
NT seq
2469 nt
NT seq
+upstream
nt +downstream
nt
atggctctggcaaaggtgcctgggacctgcttactcaccattcgtgtcctgcaggcccat
ggcctgccctccaaggaccttgtgacctcctctgactgctacgtgaccctgtggctgccc
acggcctccagccaccagctgcagacgcgcacagtcaagaactgcagaaaccctgtctgg
aatcagagctttcacttccgaatccatagccagatcaaggtggatgggcgtcagccctgg
ccccgctcactgtcccccactgttgcctcccagcctcttgttccctgcctcaccccctct
tcctgcaggcccctcactctatttccctttcagaacattgtgcatctcagagtctttgac
caagaccttctgaccacggatgaccctgtgttgtcagtgctgtttgacgtggggaccttg
cgggctggggagacccggcgcaagagcttctcgctgagccctcagggtgaggaacgcctg
gaagttgaatttcggctgcaaaatctgactgatggtgctgagtacctcttcagcaatggc
atcctagtggcccgggagctctcctgcttgcatgttcgactggagaaggcaggggacttt
caggagtcggagggcagagttcagcttgtggttcctgggtcctgtgagggtccacaggaa
gccttcgtgggtgccggctccttccgcttccattggccagcctgctgggagcaggagctg
agtattcacctgcaggatgccccccaagagcagctgaaggtgcccctgagggctctgccc
tctggccaagtggtgcgactcgtcttccctacgtcccaggagcccctgatgaaagtggag
ctgaaaaatgaagaaggatccagggaactggctgtgcggctgggctgcgggccctgtgct
gaggagcaggccttcctgagcaggaggaagcaggtggtagccaaggccctgcagcaggcc
ctgcagctggatggagacctgcgggaagaggagattccagtggttgctgttatggccact
ggtggtggtatccgggccatgacctcactgtatggacagctggctggcctaaaggcgctt
ggcctcttggattgtgtctcctacatcacaggggcctcgggctccacctgggctttggcc
aacctctacgaggatccagagtggtctcagaaggacctggcagggcccatcgagtcactg
aagacccaggtgaccaagagcaagctgggtgtgctagcccccaggcagctactgcggtac
cagcaggagctggctgagcgtgcccgcctgggccacccgacctgcttcaccaacctgtgg
gccctcgtcaacgaggcgctgctacatgacgagcctcatgactacaagctctcagaccag
cgggaggccctgagtcgaggccagaaccccctgcccatttactgtgctctcaacaccaag
gaacagaatctgaccacctttgaatttggggagtggtgtgagttctccccctacgaggtc
ggctttcccaagtatggcgccttcatcccccccgagctcttcggctctgagttcttcatg
gggcgcctgacaaaacagcttcctgagtcccgtatctgtttcctggaaggtatctggagc
aacctgtacgcagccaacctccaggacagcctgtactggtcatccgagcccagccagttc
tgggaccgctgggcacaagctcgagccagcctggacaaggagcaggtcccccttctgaag
atagaagagcctcccacggtggccggcagcatagcggaggttttcaccgaccttctgacg
cggcgtccacttgcccaggccacccacaacttcctacgtggcttctccttccacaaggac
tatttccagcaccctcacttttctgcctggaaagctaccaaactggacggccttcccaac
gagctgacacctgcagagccctacctttgcttgctggatgttgggtaccttgtcaatacc
agctgcccacccctcctgccgcccacacgggacgtggacctcatcctgtcgctagattac
aatctccatggagccttccagcagctgcagcttctgggtcggttctgccaagagcagggc
atcccgttcccgcccatctcgcccagccccgaggagcagtgccagccccaagagtgccac
cttttctcggaccccgcccgccctgacatccctgccgtgctgcacttccctctggtcaat
gcctccttcagggaccactctgcccccggggtccgacggacagccgaggagcaggcggct
ggggaagtgaacctatctgaatccgactccccctaccactactcgaaggtgacctacagc
ctggaggacgtggacaagctgctccgcctgacgcagtacaacatttgcaacaaccaggag
cggctgctggaggccctgcgtgaggccatgcagaggcggaggcagcgcacgcagcgccgg
cctgagtga
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