KEGG   Ovis aries (sheep): 101115640
Entry
101115640         CDS       T03117                                 
Symbol
GNAS
Name
(RefSeq) guanine nucleotide-binding protein G(s) subunit alpha isoforms short isoform X5
  KO
K04632  guanine nucleotide-binding protein G(s) subunit alpha
Organism
oas  Ovis aries (sheep)
Pathway
oas01522  Endocrine resistance
oas04015  Rap1 signaling pathway
oas04020  Calcium signaling pathway
oas04024  cAMP signaling pathway
oas04072  Phospholipase D signaling pathway
oas04081  Hormone signaling
oas04082  Neuroactive ligand signaling
oas04261  Adrenergic signaling in cardiomyocytes
oas04270  Vascular smooth muscle contraction
oas04540  Gap junction
oas04611  Platelet activation
oas04713  Circadian entrainment
oas04714  Thermogenesis
oas04724  Glutamatergic synapse
oas04726  Serotonergic synapse
oas04728  Dopaminergic synapse
oas04730  Long-term depression
oas04750  Inflammatory mediator regulation of TRP channels
oas04911  Insulin secretion
oas04912  GnRH signaling pathway
oas04913  Ovarian steroidogenesis
oas04915  Estrogen signaling pathway
oas04916  Melanogenesis
oas04918  Thyroid hormone synthesis
oas04921  Oxytocin signaling pathway
oas04922  Glucagon signaling pathway
oas04923  Regulation of lipolysis in adipocytes
oas04924  Renin secretion
oas04925  Aldosterone synthesis and secretion
oas04926  Relaxin signaling pathway
oas04927  Cortisol synthesis and secretion
oas04928  Parathyroid hormone synthesis, secretion and action
oas04934  Cushing syndrome
oas04935  Growth hormone synthesis, secretion and action
oas04961  Endocrine and other factor-regulated calcium reabsorption
oas04962  Vasopressin-regulated water reabsorption
oas04970  Salivary secretion
oas04971  Gastric acid secretion
oas04972  Pancreatic secretion
oas04976  Bile secretion
oas05012  Parkinson disease
oas05030  Cocaine addiction
oas05031  Amphetamine addiction
oas05032  Morphine addiction
oas05034  Alcoholism
oas05142  Chagas disease
oas05146  Amoebiasis
oas05163  Human cytomegalovirus infection
oas05165  Human papillomavirus infection
oas05200  Pathways in cancer
oas05207  Chemical carcinogenesis - receptor activation
oas05414  Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:oas00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    101115640 (GNAS)
   04020 Calcium signaling pathway
    101115640 (GNAS)
   04072 Phospholipase D signaling pathway
    101115640 (GNAS)
   04024 cAMP signaling pathway
    101115640 (GNAS)
  09133 Signaling molecules and interaction
   04082 Neuroactive ligand signaling
    101115640 (GNAS)
   04081 Hormone signaling
    101115640 (GNAS)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04540 Gap junction
    101115640 (GNAS)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    101115640 (GNAS)
  09152 Endocrine system
   04911 Insulin secretion
    101115640 (GNAS)
   04922 Glucagon signaling pathway
    101115640 (GNAS)
   04923 Regulation of lipolysis in adipocytes
    101115640 (GNAS)
   04912 GnRH signaling pathway
    101115640 (GNAS)
   04913 Ovarian steroidogenesis
    101115640 (GNAS)
   04915 Estrogen signaling pathway
    101115640 (GNAS)
   04921 Oxytocin signaling pathway
    101115640 (GNAS)
   04926 Relaxin signaling pathway
    101115640 (GNAS)
   04935 Growth hormone synthesis, secretion and action
    101115640 (GNAS)
   04918 Thyroid hormone synthesis
    101115640 (GNAS)
   04928 Parathyroid hormone synthesis, secretion and action
    101115640 (GNAS)
   04916 Melanogenesis
    101115640 (GNAS)
   04924 Renin secretion
    101115640 (GNAS)
   04925 Aldosterone synthesis and secretion
    101115640 (GNAS)
   04927 Cortisol synthesis and secretion
    101115640 (GNAS)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    101115640 (GNAS)
   04270 Vascular smooth muscle contraction
    101115640 (GNAS)
  09154 Digestive system
   04970 Salivary secretion
    101115640 (GNAS)
   04971 Gastric acid secretion
    101115640 (GNAS)
   04972 Pancreatic secretion
    101115640 (GNAS)
   04976 Bile secretion
    101115640 (GNAS)
  09155 Excretory system
   04962 Vasopressin-regulated water reabsorption
    101115640 (GNAS)
   04961 Endocrine and other factor-regulated calcium reabsorption
    101115640 (GNAS)
  09156 Nervous system
   04724 Glutamatergic synapse
    101115640 (GNAS)
   04728 Dopaminergic synapse
    101115640 (GNAS)
   04726 Serotonergic synapse
    101115640 (GNAS)
   04730 Long-term depression
    101115640 (GNAS)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    101115640 (GNAS)
  09159 Environmental adaptation
   04713 Circadian entrainment
    101115640 (GNAS)
   04714 Thermogenesis
    101115640 (GNAS)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    101115640 (GNAS)
   05207 Chemical carcinogenesis - receptor activation
    101115640 (GNAS)
  09172 Infectious disease: viral
   05163 Human cytomegalovirus infection
    101115640 (GNAS)
   05165 Human papillomavirus infection
    101115640 (GNAS)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    101115640 (GNAS)
   05142 Chagas disease
    101115640 (GNAS)
  09164 Neurodegenerative disease
   05012 Parkinson disease
    101115640 (GNAS)
  09165 Substance dependence
   05030 Cocaine addiction
    101115640 (GNAS)
   05031 Amphetamine addiction
    101115640 (GNAS)
   05032 Morphine addiction
    101115640 (GNAS)
   05034 Alcoholism
    101115640 (GNAS)
  09166 Cardiovascular disease
   05414 Dilated cardiomyopathy
    101115640 (GNAS)
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    101115640 (GNAS)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    101115640 (GNAS)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:oas04147]
    101115640 (GNAS)
   04031 GTP-binding proteins [BR:oas04031]
    101115640 (GNAS)
Exosome [BR:oas04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   101115640 (GNAS)
  Exosomal proteins of other body fluids (saliva and urine)
   101115640 (GNAS)
  Exosomal proteins of colorectal cancer cells
   101115640 (GNAS)
  Exosomal proteins of bladder cancer cells
   101115640 (GNAS)
GTP-binding proteins [BR:oas04031]
 Heterotrimeric G-proteins
  Alpha Subunits
   Alpha type 2 (Gs)
    101115640 (GNAS)
SSDB
Motif
Pfam: G-alpha Arf Gtr1_RagA Roc GTP_EFTU TniB AAA_29 nSTAND_NTPase5 FtsK_SpoIIIE
Other DBs
NCBI-GeneID: 101115640
NCBI-ProteinID: XP_027832797
LinkDB
Position
13:complement(57152612..57219531)
AA seq 395 aa
MGCLGNSKTEDQRNEEKAQREANKKIEKQLQKDKQVYRATHRLLLLGAGESGKSTIVKQM
RILHVNGFNGEGGEEDPQAARSNSDGSEKATKVQDIKNNLKEAIETIVAAMSNLVPPVEL
ANPENQFRVDYILSVMNVPDFDFPPEFYEHAKALWEDEGVRACYERSNEYQLIDCAQYFL
DKIDVIKQDDYVPSDQDLLRCRVLTSGIFETKFQVDKVNFHMFDVGGQRDERRKWIQCFN
DVTAIIFVVASSSYNMVIREDNQTNRLQEALNLFKSIWNNRWLRTISVILFLNKQDLLAE
KVLAGKSKIEDYFPEFARYTTPEDATPEPGEDPRVTRAKYFIRDEFLRISTASGDGRHYC
YPHFTCAVDTENIRRVFNDCRDIIQRMHLRQYELL
NT seq 1188 nt   +upstreamnt  +downstreamnt
atgggctgtctcggaaacagcaagaccgaggaccagcgcaacgaggagaaggcgcagcgc
gaggccaacaagaagatcgagaagcagctgcagaaggacaagcaggtctaccgggccacg
caccgtctgctgctgctgggtgctggagaatctggtaaaagcaccattgtgaagcaaatg
aggatcctgcatgttaatgggtttaatggagagggcggcgaagaggacccgcaggctgca
aggagcaacagcgatggtagtgagaaggccaccaaagtgcaggacatcaaaaacaacctg
aaagaggccattgaaaccatcgtggccgccatgagcaacctggtgccccctgtggagctg
gccaacccagagaaccagttcagagtggattacattctgagcgtgatgaacgtgccggat
tttgatttccctcccgaattctatgagcatgccaaggctctctgggaggatgaaggggtg
cgtgcctgctatgagcgctccaatgagtaccagctgattgactgcgcccagtacttcctg
gacaagattgacgtcatcaagcaggatgactatgtgcccagcgaccaggatctgctccgc
tgccgtgtcctgacttctggaatctttgagaccaagttccaggtggacaaagtcaacttc
cacatgtttgacgtgggcggccagcgcgatgaacgccgcaaatggatccaatgcttcaat
gatgtgactgccatcatcttcgtggttgccagcagcagctacaacatggtcattcgggag
gacaaccagaccaaccgcctgcaggaggctctgaacctcttcaagagcatctggaacaac
agatggctgcgcaccatctctgtgattctgttcctcaacaagcaagatctgctggctgag
aaagtccttgctggaaaatcgaagattgaggactactttccagaatttgctcgctacact
actcctgaggatgcgactcccgagcctggagaggacccacgcgtgacccgggccaagtac
ttcattcgagatgaatttctgagaatcagcactgctagtggagatgggcgccactactgc
taccctcacttcacctgcgctgtggacaccgagaacatccgccgtgtgttcaacgactgc
cgtgacatcatccagcgcatgcacctccgtcagtatgagctgctctaa

DBGET integrated database retrieval system