Ovis aries (sheep): 101117248
Help
Entry
101117248 CDS
T03117
Symbol
TYK2
Name
(RefSeq) non-receptor tyrosine-protein kinase TYK2
KO
K11219
non-receptor tyrosine-protein kinase TYK2 [EC:
2.7.10.2
]
Organism
oas
Ovis aries (sheep)
Pathway
oas04217
Necroptosis
oas04380
Osteoclast differentiation
oas04620
Toll-like receptor signaling pathway
oas04621
NOD-like receptor signaling pathway
oas04630
JAK-STAT signaling pathway
oas04658
Th1 and Th2 cell differentiation
oas04659
Th17 cell differentiation
oas05145
Toxoplasmosis
oas05160
Hepatitis C
oas05161
Hepatitis B
oas05162
Measles
oas05164
Influenza A
oas05165
Human papillomavirus infection
oas05167
Kaposi sarcoma-associated herpesvirus infection
oas05168
Herpes simplex virus 1 infection
oas05169
Epstein-Barr virus infection
oas05171
Coronavirus disease - COVID-19
Brite
KEGG Orthology (KO) [BR:
oas00001
]
09130 Environmental Information Processing
09132 Signal transduction
04630 JAK-STAT signaling pathway
101117248 (TYK2)
09140 Cellular Processes
09143 Cell growth and death
04217 Necroptosis
101117248 (TYK2)
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
101117248 (TYK2)
04621 NOD-like receptor signaling pathway
101117248 (TYK2)
04658 Th1 and Th2 cell differentiation
101117248 (TYK2)
04659 Th17 cell differentiation
101117248 (TYK2)
09158 Development and regeneration
04380 Osteoclast differentiation
101117248 (TYK2)
09160 Human Diseases
09172 Infectious disease: viral
05161 Hepatitis B
101117248 (TYK2)
05160 Hepatitis C
101117248 (TYK2)
05171 Coronavirus disease - COVID-19
101117248 (TYK2)
05164 Influenza A
101117248 (TYK2)
05162 Measles
101117248 (TYK2)
05168 Herpes simplex virus 1 infection
101117248 (TYK2)
05167 Kaposi sarcoma-associated herpesvirus infection
101117248 (TYK2)
05169 Epstein-Barr virus infection
101117248 (TYK2)
05165 Human papillomavirus infection
101117248 (TYK2)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
101117248 (TYK2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
oas01001
]
101117248 (TYK2)
Enzymes [BR:
oas01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
101117248 (TYK2)
Protein kinases [BR:
oas01001
]
Non-receptor tyrosine kinases
JAK family [OT]
101117248 (TYK2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
Jak1_Phl
FERM_F2
FERM_F1
SH2_1
Kinase-like
Kdo
FERM_C_FAK1
ABC1
Motif
Other DBs
NCBI-GeneID:
101117248
NCBI-ProteinID:
XP_027825425
LinkDB
All DBs
Position
5:complement(12731954..12761361)
Genome browser
AA seq
1187 aa
AA seq
DB search
MPLCQWRTTTRGRKPNGDGAQPMATREGLKVLLHWAGPSGGEPWVTFTEPTLTAEDVCIR
IAHKVGITPPCFNLFALFDAQAQVWLPPNHILDTSRDSSLTLYFRMRFYFRNWHGTNPQE
PAVYRCGPPGPETSSEQAEQGVQLLDPASFEYLFEQGKHEFVNDVASLCELSSEEEIHHF
QNESLGMALLHLCHLALRSGVPLEKVAKKTSFKDCIPRSFRRQIRQHNVLTRVRQRSIFR
KFLQAFQPGCLSQQVIMVKYLATLERLAPRFGTERVPVCHLELLSQAEGEPCYLRDGGQA
PADPGSESAAGPPTHEVLVSGTKGIRWRLVTAEGPADGGGGGGSTMPDADPSGKRMKAKE
AGGEPVDRPRETPWSYFCDFQDITHMVLKECHVSIHCQDNKCLELTLPSRAAALSLVSLV
DGYFRLTADSNHYLCHEVAPPRLVMSIQDGIHGPLLDPFVLAKLKPEAGLYLIQWSTSHL
HRLILTVAQRDQLQAPGTKGLRLRKFPIELRAGTVMLEGWGRSFPSVRDLRAALQDCSLR
AGDDCFPLRRCCLPRPGEISNLIVTRGPQASTRQLNLSHLSFYRVRQEDITQLSHLGQGT
RTNVYEGLLRVGGGGPEEDKANGEEPPTPAGDCGQELRVVLKILDPSHHDIALAFYETAS
LMSQVSHVHLAFVHGVFVHGSENIMVTEYVEHGPLDVWLRRERGRVPLAWKLAVAQQLAS
ALSYLEDKSLVHGNVCGRNVLLARLGLAEGTSPFIKLSDPGVGLSALSREERVERIPWTA
PECLSGGANSLSTAADKWGFGATLLEICFDGEAPLQGRSPSEKERFYQKQHKLPEPSCPE
LATLTSQCLTYEPAQRPSFRTILRDFTQLQPQNLADVLSVSPDSLASDPTVFHKRYLKKI
RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKAGCGPQLRTGWRREIDILRALYHKHIV
KYKGCCEDQGEKSVQLVMEYMPLGSLRDYLPRHNVGLVQLLLFSLQICEGMAYLHTQHYV
HRDLAARNVLLDNNRLVKIGDFGLTKAVPEGHEYYCVREDGDSPVFWYAPECLKDCKFYY
ASDVWSFGVLMYELLTYCDSSQSPPSKFIELMGLTQGQMTVLRLMELLERGERLPQPERC
PSEIYCLMKDCWKAEASLRPTFQNLVPVLRSYHEKYQGLAPSVFSVC
NT seq
3564 nt
NT seq
+upstream
nt +downstream
nt
atgcctctgtgccaatggaggaccaccaccaggggcaggaagcccaatggggacggagct
cagcccatggccaccagagaaggcctgaaagtacttctgcactgggctggccccagtggt
ggggaaccctgggtcaccttcactgagcccacactgaccgcggaggatgtctgcatccgc
atcgcacacaaagtcggcatcactccaccctgcttcaatctttttgccctcttcgatgcc
caggcccaggtctggctgcctccaaatcacatcctggatacctccagggactccagcctg
acgctgtacttccgcatgaggttttatttccgaaactggcatggcacaaatcctcaggag
ccggctgtgtaccgctgcgggcccccagggcccgagacttcctcagaacaggcagagcag
ggggtgcaactcctggaccctgcctcctttgagtacctctttgagcagggcaagcatgag
tttgtaaatgacgtggcatcactatgtgagctatccagcgaggaggagatccaccacttt
cagaatgagagcctgggcatggcccttttgcacctctgccaccttgctctccgcagtggt
gtcccccttgaaaaggtggccaagaagaccagcttcaaggattgcatcccacgctccttc
cggcggcagatccggcagcacaacgttctgacacgggtgcgccaacggagcatcttccgc
aagttcctgcaggccttccagcccggctgcctctcccagcaggtcatcatggtgaagtac
ctggccacgctcgagcgactggcaccccgctttggcacagagcgtgtgcccgtgtgccac
ctggagttgctgtcccaggctgagggggagccctgctacctccgggacggtgggcaggcc
cctgccgatcccgggtctgagtctgctgccggaccccccacccacgaggtgctggtgtca
ggcacgaaaggcatccgatggcggctggtaacggcagaggggcctgctgatggtggtggt
ggtggcggcagtacgatgcctgatgctgacccatctgggaagagaatgaaggccaaggag
gcgggcggcgagccagtggacaggcctcgggagaccccctggtcctacttttgtgacttc
caggacatcacccacatggtgctgaaggaatgccacgtcagcatccactgtcaggacaac
aagtgcctggagctgaccctgccttcccgggctgcggccctgtccttggtgtcgctggtg
gatggctactttcgcctgaccgccgactcaaaccactacctgtgccacgaggtggctcct
ccacggctggtgatgagtatccaggatggtatccacggccccctgctggatccattcgtg
ctggccaagctgaagcctgaggctggcctctaccttatccagtggagcaccagccacctc
caccgcctcatcctcacagtggcccagcgcgaccagctgcaggctcccggcaccaagggc
ttgcgcctgcggaagttccccatcgagctccgggccgggacagtcatgctggagggctgg
ggccggtctttccccagcgtgcgggacctgcgggccgccctacaggactgctcgctgcgg
gccggcgacgactgctttcccctgcgtcgctgctgcctgccccggccgggagagatctcc
aacctcattgtcacacgggggcctcaggccagcaccagacagctcaacctcagtcatctc
agcttctaccgagtccgccaggaagacatcacccagctgtcccacttgggccagggcaca
aggaccaacgtgtatgagggcctcttgcgagtagggggcggaggccccgaggaggacaag
gcaaatggcgaggaaccccccacgcccgctggggactgtgggcaagagctgcgtgtggtg
ctcaagatcctagaccccagtcaccacgacatcgccctggccttctacgagacagccagc
ctcatgagccaggtctcccacgtgcacctggccttcgtgcacggcgtcttcgtgcacggc
tccgagaacatcatggtgaccgagtatgtggagcacgggcccctggacgtatggctgcgg
cgggagaggggccgcgtgcccctggcctggaagttggcagtggcccagcagctggccagc
gccctcagctacctggaagacaaaagcctggttcatggcaacgtgtgtggccggaacgtc
ctgctggcacggctggggctggcggagggcaccagccccttcatcaagctgagcgacccc
ggcgtgggcctgagtgccctctccagggaggagcgggtggagcggatcccctggacagcc
cccgagtgcctatctggtggagccaacagcctgagcaccgcagccgacaagtggggcttt
ggtgccaccctcctggagatctgctttgacggcgaggcccccctgcagggccgcagtccc
tctgagaaagagcgcttctaccagaagcagcacaaactgcccgagccctcgtgcccagag
ctggccacactcaccagccagtgcttgacctatgagccagcccagcggccatccttccgc
accatcctgcgtgacttcactcagctacagccccagaatctcgctgatgtcttgtctgtg
agcccggattcactggcttcagatcccacggttttccacaagcgatacttgaaaaagatc
cgggatctgggcgagggtcacttcggaaaggtcagcctgtattgctacgaccccaccaac
gacggcactggtgagatggtagccgtgaaggctctcaaggcaggctgcggtccccagctc
cggacgggctggaggcgagaaatcgacatcctacgcgcgctctaccacaagcacatcgtc
aagtacaagggctgctgcgaggaccaaggcgagaagtcggtacagctggtcatggaatac
atgcccctgggcagcctccgagactacttgccccggcacaatgtcgggctggtccagctg
ctgctcttctccctgcagatctgcgagggtatggcctacctgcatacacagcactacgtg
catcgagacctggccgcgcgcaacgtgctgctggacaacaacaggctggtcaagatcggg
gacttcggcctcaccaaggccgtgcccgaaggccacgagtattactgcgtgcgtgaggat
ggggacagtcctgtgttctggtatgccccggagtgcctgaaggattgtaagttctactat
gcatcagacgtctggtcctttggggtcctcatgtatgagctgctgacctactgtgactcc
agccagagccctccctcgaaattcatcgagctcatgggcctcacccaagggcagatgact
gtgctgaggctcatggagctgctggaacgaggggagaggctgccacaaccagagagatgc
ccctctgagatctattgcctcatgaaggactgctggaaggcagaggcctcactccgcccg
accttccagaacctcgtacccgtcctcagatcataccacgagaaataccaaggcctggcc
ccctcggtgttcagtgtctgctga
DBGET
integrated database retrieval system
