Ovis aries (sheep): 101117348
Help
Entry
101117348 CDS
T03117
Symbol
PIK3CD
Name
(RefSeq) phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform isoform X3
KO
K00922
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:
2.7.1.153
]
Organism
oas
Ovis aries (sheep)
Pathway
oas00562
Inositol phosphate metabolism
oas01100
Metabolic pathways
oas01521
EGFR tyrosine kinase inhibitor resistance
oas01522
Endocrine resistance
oas01524
Platinum drug resistance
oas04012
ErbB signaling pathway
oas04014
Ras signaling pathway
oas04015
Rap1 signaling pathway
oas04024
cAMP signaling pathway
oas04062
Chemokine signaling pathway
oas04066
HIF-1 signaling pathway
oas04068
FoxO signaling pathway
oas04070
Phosphatidylinositol signaling system
oas04071
Sphingolipid signaling pathway
oas04072
Phospholipase D signaling pathway
oas04081
Hormone signaling
oas04140
Autophagy - animal
oas04145
Phagocytosis
oas04150
mTOR signaling pathway
oas04151
PI3K-Akt signaling pathway
oas04152
AMPK signaling pathway
oas04210
Apoptosis
oas04211
Longevity regulating pathway
oas04213
Longevity regulating pathway - multiple species
oas04218
Cellular senescence
oas04360
Axon guidance
oas04370
VEGF signaling pathway
oas04380
Osteoclast differentiation
oas04510
Focal adhesion
oas04517
IgSF CAM signaling
oas04518
Integrin signaling
oas04550
Signaling pathways regulating pluripotency of stem cells
oas04611
Platelet activation
oas04613
Neutrophil extracellular trap formation
oas04620
Toll-like receptor signaling pathway
oas04625
C-type lectin receptor signaling pathway
oas04630
JAK-STAT signaling pathway
oas04650
Natural killer cell mediated cytotoxicity
oas04660
T cell receptor signaling pathway
oas04662
B cell receptor signaling pathway
oas04664
Fc epsilon RI signaling pathway
oas04666
Fc gamma R-mediated phagosome formation
oas04668
TNF signaling pathway
oas04670
Leukocyte transendothelial migration
oas04722
Neurotrophin signaling pathway
oas04725
Cholinergic synapse
oas04750
Inflammatory mediator regulation of TRP channels
oas04810
Regulation of actin cytoskeleton
oas04910
Insulin signaling pathway
oas04914
Progesterone-mediated oocyte maturation
oas04915
Estrogen signaling pathway
oas04917
Prolactin signaling pathway
oas04919
Thyroid hormone signaling pathway
oas04923
Regulation of lipolysis in adipocytes
oas04926
Relaxin signaling pathway
oas04929
GnRH secretion
oas04930
Type II diabetes mellitus
oas04931
Insulin resistance
oas04932
Non-alcoholic fatty liver disease
oas04933
AGE-RAGE signaling pathway in diabetic complications
oas04935
Growth hormone synthesis, secretion and action
oas04960
Aldosterone-regulated sodium reabsorption
oas04973
Carbohydrate digestion and absorption
oas05010
Alzheimer disease
oas05017
Spinocerebellar ataxia
oas05020
Prion disease
oas05100
Bacterial invasion of epithelial cells
oas05132
Salmonella infection
oas05135
Yersinia infection
oas05142
Chagas disease
oas05146
Amoebiasis
oas05160
Hepatitis C
oas05161
Hepatitis B
oas05162
Measles
oas05163
Human cytomegalovirus infection
oas05164
Influenza A
oas05165
Human papillomavirus infection
oas05166
Human T-cell leukemia virus 1 infection
oas05167
Kaposi sarcoma-associated herpesvirus infection
oas05168
Herpes simplex virus 1 infection
oas05169
Epstein-Barr virus infection
oas05170
Human immunodeficiency virus 1 infection
oas05171
Coronavirus disease
oas05200
Pathways in cancer
oas05203
Viral carcinogenesis
oas05205
Proteoglycans in cancer
oas05206
MicroRNAs in cancer
oas05207
Chemical carcinogenesis - receptor activation
oas05208
Chemical carcinogenesis - reactive oxygen species
oas05210
Colorectal cancer
oas05211
Renal cell carcinoma
oas05212
Pancreatic cancer
oas05213
Endometrial cancer
oas05214
Glioma
oas05215
Prostate cancer
oas05218
Melanoma
oas05220
Chronic myeloid leukemia
oas05221
Acute myeloid leukemia
oas05222
Small cell lung cancer
oas05223
Non-small cell lung cancer
oas05224
Breast cancer
oas05225
Hepatocellular carcinoma
oas05226
Gastric cancer
oas05230
Central carbon metabolism in cancer
oas05231
Choline metabolism in cancer
oas05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
oas05415
Diabetic cardiomyopathy
oas05417
Lipid and atherosclerosis
oas05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
oas00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00562 Inositol phosphate metabolism
101117348 (PIK3CD)
09130 Environmental Information Processing
09132 Signal transduction
04012 ErbB signaling pathway
101117348 (PIK3CD)
04014 Ras signaling pathway
101117348 (PIK3CD)
04015 Rap1 signaling pathway
101117348 (PIK3CD)
04370 VEGF signaling pathway
101117348 (PIK3CD)
04630 JAK-STAT signaling pathway
101117348 (PIK3CD)
04668 TNF signaling pathway
101117348 (PIK3CD)
04066 HIF-1 signaling pathway
101117348 (PIK3CD)
04068 FoxO signaling pathway
101117348 (PIK3CD)
04070 Phosphatidylinositol signaling system
101117348 (PIK3CD)
04072 Phospholipase D signaling pathway
101117348 (PIK3CD)
04071 Sphingolipid signaling pathway
101117348 (PIK3CD)
04024 cAMP signaling pathway
101117348 (PIK3CD)
04151 PI3K-Akt signaling pathway
101117348 (PIK3CD)
04152 AMPK signaling pathway
101117348 (PIK3CD)
04150 mTOR signaling pathway
101117348 (PIK3CD)
09133 Signaling molecules and interaction
04081 Hormone signaling
101117348 (PIK3CD)
04517 IgSF CAM signaling
101117348 (PIK3CD)
04518 Integrin signaling
101117348 (PIK3CD)
09140 Cellular Processes
09141 Transport and catabolism
04145 Phagocytosis
101117348 (PIK3CD)
04140 Autophagy - animal
101117348 (PIK3CD)
09143 Cell growth and death
04210 Apoptosis
101117348 (PIK3CD)
04218 Cellular senescence
101117348 (PIK3CD)
09144 Cellular community - eukaryotes
04510 Focal adhesion
101117348 (PIK3CD)
04550 Signaling pathways regulating pluripotency of stem cells
101117348 (PIK3CD)
09142 Cell motility
04810 Regulation of actin cytoskeleton
101117348 (PIK3CD)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
101117348 (PIK3CD)
04613 Neutrophil extracellular trap formation
101117348 (PIK3CD)
04620 Toll-like receptor signaling pathway
101117348 (PIK3CD)
04625 C-type lectin receptor signaling pathway
101117348 (PIK3CD)
04650 Natural killer cell mediated cytotoxicity
101117348 (PIK3CD)
04660 T cell receptor signaling pathway
101117348 (PIK3CD)
04662 B cell receptor signaling pathway
101117348 (PIK3CD)
04664 Fc epsilon RI signaling pathway
101117348 (PIK3CD)
04666 Fc gamma R-mediated phagosome formation
101117348 (PIK3CD)
04670 Leukocyte transendothelial migration
101117348 (PIK3CD)
04062 Chemokine signaling pathway
101117348 (PIK3CD)
09152 Endocrine system
04910 Insulin signaling pathway
101117348 (PIK3CD)
04923 Regulation of lipolysis in adipocytes
101117348 (PIK3CD)
04929 GnRH secretion
101117348 (PIK3CD)
04915 Estrogen signaling pathway
101117348 (PIK3CD)
04914 Progesterone-mediated oocyte maturation
101117348 (PIK3CD)
04917 Prolactin signaling pathway
101117348 (PIK3CD)
04926 Relaxin signaling pathway
101117348 (PIK3CD)
04935 Growth hormone synthesis, secretion and action
101117348 (PIK3CD)
04919 Thyroid hormone signaling pathway
101117348 (PIK3CD)
09154 Digestive system
04973 Carbohydrate digestion and absorption
101117348 (PIK3CD)
09155 Excretory system
04960 Aldosterone-regulated sodium reabsorption
101117348 (PIK3CD)
09156 Nervous system
04725 Cholinergic synapse
101117348 (PIK3CD)
04722 Neurotrophin signaling pathway
101117348 (PIK3CD)
09157 Sensory system
04750 Inflammatory mediator regulation of TRP channels
101117348 (PIK3CD)
09158 Development and regeneration
04360 Axon guidance
101117348 (PIK3CD)
04380 Osteoclast differentiation
101117348 (PIK3CD)
09149 Aging
04211 Longevity regulating pathway
101117348 (PIK3CD)
04213 Longevity regulating pathway - multiple species
101117348 (PIK3CD)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
101117348 (PIK3CD)
05206 MicroRNAs in cancer
101117348 (PIK3CD)
05205 Proteoglycans in cancer
101117348 (PIK3CD)
05207 Chemical carcinogenesis - receptor activation
101117348 (PIK3CD)
05208 Chemical carcinogenesis - reactive oxygen species
101117348 (PIK3CD)
05203 Viral carcinogenesis
101117348 (PIK3CD)
05230 Central carbon metabolism in cancer
101117348 (PIK3CD)
05231 Choline metabolism in cancer
101117348 (PIK3CD)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
101117348 (PIK3CD)
09162 Cancer: specific types
05210 Colorectal cancer
101117348 (PIK3CD)
05212 Pancreatic cancer
101117348 (PIK3CD)
05225 Hepatocellular carcinoma
101117348 (PIK3CD)
05226 Gastric cancer
101117348 (PIK3CD)
05214 Glioma
101117348 (PIK3CD)
05221 Acute myeloid leukemia
101117348 (PIK3CD)
05220 Chronic myeloid leukemia
101117348 (PIK3CD)
05218 Melanoma
101117348 (PIK3CD)
05211 Renal cell carcinoma
101117348 (PIK3CD)
05215 Prostate cancer
101117348 (PIK3CD)
05213 Endometrial cancer
101117348 (PIK3CD)
05224 Breast cancer
101117348 (PIK3CD)
05222 Small cell lung cancer
101117348 (PIK3CD)
05223 Non-small cell lung cancer
101117348 (PIK3CD)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
101117348 (PIK3CD)
05170 Human immunodeficiency virus 1 infection
101117348 (PIK3CD)
05161 Hepatitis B
101117348 (PIK3CD)
05160 Hepatitis C
101117348 (PIK3CD)
05171 Coronavirus disease
101117348 (PIK3CD)
05164 Influenza A
101117348 (PIK3CD)
05162 Measles
101117348 (PIK3CD)
05168 Herpes simplex virus 1 infection
101117348 (PIK3CD)
05163 Human cytomegalovirus infection
101117348 (PIK3CD)
05167 Kaposi sarcoma-associated herpesvirus infection
101117348 (PIK3CD)
05169 Epstein-Barr virus infection
101117348 (PIK3CD)
05165 Human papillomavirus infection
101117348 (PIK3CD)
09171 Infectious disease: bacterial
05132 Salmonella infection
101117348 (PIK3CD)
05135 Yersinia infection
101117348 (PIK3CD)
05100 Bacterial invasion of epithelial cells
101117348 (PIK3CD)
09174 Infectious disease: parasitic
05146 Amoebiasis
101117348 (PIK3CD)
05142 Chagas disease
101117348 (PIK3CD)
09164 Neurodegenerative disease
05010 Alzheimer disease
101117348 (PIK3CD)
05017 Spinocerebellar ataxia
101117348 (PIK3CD)
05020 Prion disease
101117348 (PIK3CD)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
101117348 (PIK3CD)
05418 Fluid shear stress and atherosclerosis
101117348 (PIK3CD)
05415 Diabetic cardiomyopathy
101117348 (PIK3CD)
09167 Endocrine and metabolic disease
04930 Type II diabetes mellitus
101117348 (PIK3CD)
04932 Non-alcoholic fatty liver disease
101117348 (PIK3CD)
04931 Insulin resistance
101117348 (PIK3CD)
04933 AGE-RAGE signaling pathway in diabetic complications
101117348 (PIK3CD)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
101117348 (PIK3CD)
01524 Platinum drug resistance
101117348 (PIK3CD)
01522 Endocrine resistance
101117348 (PIK3CD)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
oas04131
]
101117348 (PIK3CD)
Enzymes [BR:
oas01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.1 Phosphotransferases with an alcohol group as acceptor
2.7.1.153 phosphatidylinositol-4,5-bisphosphate 3-kinase
101117348 (PIK3CD)
Membrane trafficking [BR:
oas04131
]
Endocytosis
Rab GTPases and associated proteins
Rab associated proteins
101117348 (PIK3CD)
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PI3_PI4_kinase
PI3K_p85B
PI3K_rbd
PI3K_C2
PI3Ka
Motif
Other DBs
NCBI-GeneID:
101117348
NCBI-ProteinID:
XP_027831459
LinkDB
All DBs
Position
12:complement(43042392..43103621)
Genome browser
AA seq
996 aa
AA seq
DB search
MPPGVDCPMEFWTKEENQNVAVDFLLPTGVYLNFPVSRNANLSTIKKVLWHRAQYEPLFH
MLSDPEAYVFTCVNQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLQDPEVNDFRGKMRQFCEEAAARRQQLGWEAWLQYSFPLQLEPSARSWGP
GTLRIPNRALLVNVKFEGSEESFTFQVSTKDVPLALMACALRKKATVFRQPLVEQPEDYT
LQVNGKHEYLYGSYPLCQFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSNPAPQVQKPR
TKPPPIPMKKPSSVSLWSLEQPFYIELIQGSKVNADERMKLVVQAGLFHGNETLCKTVSS
SEVSVCSEPVWKQRLEFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
ANLMLFDYKDQLKTGERCLYMWPSVPDEKGELLNPCGTVRSNPNTESAAALVIFLPEVAP
HPVYYPSLDKILELGRLGEHGRFTEEEQLQLREILERRGSGELYEHEKDLVWKMRHEIQE
HFPEALARLLLVTKWNKHEDVAQMLYLLCSWPELPVLSALELLDFSFPDRHVGSFAIKSL
RKLTSEMHVPSVALRFGLIMEAYCRGSTHHMKVLMKQGEALSKLKALNDFVKVCSQKTPK
PQAKELMHLCMRQETYLEALSHLQSPLDPSTLLAEVCVEQCTFMDSKMKPLWVMYSNEEA
GSDGTVGIIFKNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDRTGLIEVV
LHSDTIANIQLNKSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYV
LGIGDRHSDNIMIRENGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTN
NSEKFERFRGYCETAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTE
EEALKHFRVKFNEALRESWKTKVNWLAHNVSKDNRQ
NT seq
2991 nt
NT seq
+upstream
nt +downstream
nt
atgccccccggggttgactgccccatggaattctggaccaaggaggagaatcagaatgtg
gcagttgatttcttgctgcccacgggggtctatctgaacttccctgtgtcccgaaatgcc
aacctcagcactatcaagaaggtgttatggcaccgcgcccagtatgagccgctcttccac
atgctcagtgaccctgaggcctacgtgttcacctgcgtcaaccagacggcggagcagcag
gagctggaggacgagcagcggcggctctgcgacatccagcccttcctgcctgtcctgcgg
ctggtggcccgcgaaggtgaccgcgtgaagaagctcatcaactcgcagatcagcctgctc
atcggcaaaggcctccacgagtttgactccttgcaagacccggaggtgaatgacttccga
ggcaagatgcgccagttctgcgaggaggcggctgcccgcaggcagcagctgggctgggag
gcctggctgcagtacagcttccctctgcagttggagccctcagcgcggagctgggggccg
ggcaccctgcgcatccccaatcgggccctcctggtcaatgtcaagtttgagggcagcgag
gagagcttcaccttccaggtatccaccaaggatgtgcccctggcactgatggcctgcgcc
ctccgaaagaaggccacggtgttccggcagccgctggtggagcagcctgaggactacaca
ctgcaggtgaacggcaagcatgagtacctgtacggcagctaccccctctgccagttccag
tacatctgcagctgcctgcacagtgggctgaccccccacctgaccatggtgcactcctcc
tccatcctcgccatgcgggacgagcagagcaaccctgccccccaagtccagaagccacgc
accaaaccgccccccatccccatgaagaagccctcctccgtgtccctctggtccctggag
cagcctttctacatcgagctgatccagggcagcaaagtgaatgccgacgagcggatgaag
ctggtggtgcaggccgggctcttccatggcaatgagacactatgcaagacagtgtccagc
tcagaggtgagcgtatgttcggagcccgtgtggaagcagcggctggagtttgacatcaac
atctgtgacctgccccgcatggcccggctctgcttcgcgctttacgccgtgatcgagaag
gccaagaaggcccgctccaccaagaagaagtccaagaaggcggactgccccattgcctgg
gccaacctcatgctgtttgactacaaggaccagctcaagacaggcgagcgctgtctctac
atgtggccctctgtcccagacgagaaaggggagctactgaacccctgtgggaccgtgagg
agtaaccccaacactgagagtgcagccgccctggtcatctttctccccgaggtggcccct
caccctgtatactacccttccctggacaagatcctggagctggggcggcttggagagcac
ggacgcttcacggaggaggagcagctgcagctgcgggagatcctggagcggcggggttcc
ggggaactgtacgagcacgagaaggacctggtgtggaagatgcggcacgagatccaggag
cactttcccgaggctctagcccggctgctgctggtcactaagtggaacaaacacgaggac
gtggcccagatgctctacctgctctgctcctggcctgaactgccggttctgagcgccctg
gagttgctagacttcagcttccccgaccgccacgtgggctccttcgccatcaagtccctg
cggaaactaacctccgagatgcacgtgccgtcggtggctctgcgattcggcctcatcatg
gaagcctattgccggggcagcacccaccacatgaaggtgctgatgaagcagggggaagca
ctgagcaaactgaaggccctcaatgacttcgtcaaagtgtgctcccagaagacccccaaa
ccccaggccaaggagctgatgcacctgtgcatgcgccaggagacctacctggaggccctc
tcccacttgcagtccccactcgaccccagcaccctgctggctgaagtctgcgtggagcag
tgcaccttcatggactccaagatgaaacccctgtgggtcatgtacagcaacgaggaggca
ggcagcgatggcaccgtgggcatcatctttaagaatggggacgacctccgccaggacatg
ctgaccctgcagatgatccagctcatggacattctgtggaagcaggagggcttggacctg
aggatgaccccctacggctgcctctccactggggaccgcacaggccttattgaggtggtg
cttcactcggacaccattgccaacatccagctgaacaagagcaacatggcggccacggcc
gccttcaataaggatgctctgctcaactggctcaagtccaagaacccgggggaggccctg
gatcgagccattgaggagttcaccctctcctgtgctggctactgtgtggccacctatgtg
ctgggcatcggcgatcgccacagcgacaacatcatgatccgagagaacgggcagctgttc
cacattgatttcggccactttctggggaatttcaagaccaagtttggaatcaaccgtgag
cgggtcccgttcatcctcacctatgactttgtccacgtgatccagcaggggaagacgaat
aatagtgagaagtttgaaaggttccggggctattgtgagacggcctacaccatcctgcgg
cgccatgggctccttttcctccacctctttgccctgatgcgggcggcaggcctgcctgag
ctcagctgctccaaagacatccagtatctcaaggattctctggcattggggaaaacggag
gaggaggctctgaagcacttccgagtgaagtttaatgaagccctccgggaaagctggaaa
accaaagtgaactggctggcccacaacgtgtccaaagataacaggcaataa
DBGET
integrated database retrieval system