Ovis aries (sheep): 101121975
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Entry
101121975 CDS
T03117
Symbol
PDHB
Name
(RefSeq) pyruvate dehydrogenase E1 component subunit beta, mitochondrial
KO
K00162
pyruvate dehydrogenase E1 component subunit beta [EC:
1.2.4.1
]
Organism
oas
Ovis aries (sheep)
Pathway
oas00010
Glycolysis / Gluconeogenesis
oas00020
Citrate cycle (TCA cycle)
oas00620
Pyruvate metabolism
oas00785
Lipoic acid metabolism
oas01100
Metabolic pathways
oas01200
Carbon metabolism
oas01210
2-Oxocarboxylic acid metabolism
oas04066
HIF-1 signaling pathway
oas04922
Glucagon signaling pathway
oas05230
Central carbon metabolism in cancer
oas05415
Diabetic cardiomyopathy
Module
oas_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
oas00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
101121975 (PDHB)
00020 Citrate cycle (TCA cycle)
101121975 (PDHB)
00620 Pyruvate metabolism
101121975 (PDHB)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
101121975 (PDHB)
09130 Environmental Information Processing
09132 Signal transduction
04066 HIF-1 signaling pathway
101121975 (PDHB)
09150 Organismal Systems
09152 Endocrine system
04922 Glucagon signaling pathway
101121975 (PDHB)
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
101121975 (PDHB)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
101121975 (PDHB)
Enzymes [BR:
oas01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
101121975 (PDHB)
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GFIT
Motif
Pfam:
Transket_pyr
Transketolase_C
Motif
Other DBs
NCBI-GeneID:
101121975
NCBI-ProteinID:
XP_027814043
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Position
19:43025835..43031423
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AA seq
359 aa
AA seq
DB search
MAVVAVLVRRPLEQVSGLLRRQFHRTAPAALQVTVREAINQGMDEELERDEKVFLLGEEV
AQYDGAYKVSRGLWKKYGDKRIIDTPISEMGFAGIAVGAAMAGLRPICEFMTFNFSMQAI
DQVINSAAKTYYMSGGLQSVPIVFRGPNGASAGVAAQHSQCFAAWYGHCPGLKVVSPWSS
EDAKGLIKSAIRDNNPVVMLENELMYGVPFELPSEAQSKDFLIPIGKAKIERQGTHVTIV
AHSRPVGHCLEAATVLSKEGIECEVINLRTIRPMDIETIEASVMKTNHLVTVEGGWPQFG
VGAEICARIMEGPAFNFLDAPAVRVTGADVPMPYAKILEDNSVPQVKDIIFAIKKTLNI
NT seq
1080 nt
NT seq
+upstream
nt +downstream
nt
atggcggtggttgctgtgttggtgcggagaccccttgagcaggtctccgggctgctgagg
aggcagttccaccggaccgcgccggctgcactgcaggtgacagttcgtgaggctataaat
caaggcatggatgaggagctggaaagagatgagaaggtatttctccttggggaagaagtt
gcccagtacgatggggcatataaggttagtcgaggcctgtggaagaaatacggagataag
aggatcatagatactcccatatctgagatgggttttgctggaattgctgtaggtgcagct
atggctgggttacggcccatttgtgaattcatgaccttcaatttctctatgcaagccatc
gaccaggtcataaactcagctgccaagacgtactacatgtcagggggccttcagtctgtg
cccatagtcttcagggggcccaatggcgcctcagcaggtgtagctgcccagcactcacag
tgttttgctgcctggtatgggcattgcccaggcttaaaggtggtcagcccctggagttca
gaggatgcaaaagggcttattaaatcagccattcgggataacaacccagtggtgatgttg
gagaatgaattgatgtacggagtaccttttgaacttccttcagaagctcagtcaaaagat
tttctgatccctattggaaaagccaaaatagaaaggcaaggaacacacgtaactatagtt
gctcattcaagacctgtgggccactgcttagaagctgcaacagtgctgtctaaagaggga
attgaatgtgaggtgataaatttgcgaaccatcaggccaatggacattgagacaatagaa
gccagtgtcatgaagaccaatcaccttgtaaccgtggaaggaggctggccacagttcgga
gtaggagctgaaatctgtgccaggatcatggaaggccctgcgttcaatttcctggatgct
cctgcagttcgtgtcactggtgccgatgtgcctatgccttatgcaaagattctagaagac
aactctgtacctcaggttaaagacatcatatttgcaataaagaaaacactaaatatctag
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