KEGG   Ovis aries (sheep): 101122959
Entry
101122959         CDS       T03117                                 
Symbol
MAP2K3
Name
(RefSeq) dual specificity mitogen-activated protein kinase kinase 3
  KO
K04432  mitogen-activated protein kinase kinase 3 [EC:2.7.12.2]
Organism
oas  Ovis aries (sheep)
Pathway
oas04010  MAPK signaling pathway
oas04015  Rap1 signaling pathway
oas04218  Cellular senescence
oas04519  Cadherin signaling
oas04620  Toll-like receptor signaling pathway
oas04664  Fc epsilon RI signaling pathway
oas04668  TNF signaling pathway
oas04714  Thermogenesis
oas04750  Inflammatory mediator regulation of TRP channels
oas04912  GnRH signaling pathway
oas04935  Growth hormone synthesis, secretion and action
oas04936  Alcoholic liver disease
oas05014  Amyotrophic lateral sclerosis
oas05022  Pathways of neurodegeneration - multiple diseases
oas05132  Salmonella infection
oas05135  Yersinia infection
oas05145  Toxoplasmosis
oas05161  Hepatitis B
oas05169  Epstein-Barr virus infection
oas05170  Human immunodeficiency virus 1 infection
oas05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
oas05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:oas00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    101122959 (MAP2K3)
   04015 Rap1 signaling pathway
    101122959 (MAP2K3)
   04668 TNF signaling pathway
    101122959 (MAP2K3)
  09133 Signaling molecules and interaction
   04519 Cadherin signaling
    101122959 (MAP2K3)
 09140 Cellular Processes
  09143 Cell growth and death
   04218 Cellular senescence
    101122959 (MAP2K3)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    101122959 (MAP2K3)
   04664 Fc epsilon RI signaling pathway
    101122959 (MAP2K3)
  09152 Endocrine system
   04912 GnRH signaling pathway
    101122959 (MAP2K3)
   04935 Growth hormone synthesis, secretion and action
    101122959 (MAP2K3)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    101122959 (MAP2K3)
  09159 Environmental adaptation
   04714 Thermogenesis
    101122959 (MAP2K3)
 09160 Human Diseases
  09161 Cancer: overview
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    101122959 (MAP2K3)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    101122959 (MAP2K3)
   05161 Hepatitis B
    101122959 (MAP2K3)
   05169 Epstein-Barr virus infection
    101122959 (MAP2K3)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    101122959 (MAP2K3)
   05135 Yersinia infection
    101122959 (MAP2K3)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    101122959 (MAP2K3)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    101122959 (MAP2K3)
   05022 Pathways of neurodegeneration - multiple diseases
    101122959 (MAP2K3)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    101122959 (MAP2K3)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    101122959 (MAP2K3)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:oas01001]
    101122959 (MAP2K3)
Enzymes [BR:oas01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.12  Dual-specificity kinases (those acting on Ser/Thr and Tyr residues)
    2.7.12.2  mitogen-activated protein kinase kinase
     101122959 (MAP2K3)
Protein kinases [BR:oas01001]
 Serine/threonine kinases: STE group
  STE7 family
   101122959 (MAP2K3)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Kinase-like ABC1 Haspin_kinase Pkinase_fungal Seadorna_VP7 Choline_kinase APH RIO1
Other DBs
NCBI-GeneID: 101122959
NCBI-ProteinID: XP_027830548
LinkDB
Position
11:34997097..35015580
AA seq 347 aa
MESTAPSPPAGVPTSKGKSRRKKDLRISCMSKPPAPSPTLPRNLDSRAFITIGDRNFEVE
ADDLVTISELGRGAYGVVEKVRHAQSGTIMAVKRIRATVNSQEQKRLLMDLDVNMRTVDC
FYTVTFYGALFREGDVWICMELMDTSLDKFYRKVLDKGMTIPEDILGEIAVSIVRALEHL
HSKLSVIHRDVKPSNVLINKEGHVKMCDFGISGYLVDSVAKTMDAGCKPYMAPERINPEL
NQKGYNVKSDVWSLGITMIEMAILRFPYESWGTPFQQLKQVVEEPSPQLPADRFSPDFVD
FTAQCLRKNPAERMSYLELMEHPFFTSHKTKKTDIAAFVKEILGEDS
NT seq 1044 nt   +upstreamnt  +downstreamnt
atggagtctactgccccgagcccgcccgccggcgtgcccacgtccaaaggaaagtccagg
aggaaaaaggatttacgaatctcctgcatgtccaagccgccggcgcccagccccacgctc
ccccggaacctggactcccgggctttcatcaccattggagacaggaactttgaggtggag
gcggatgacctggtgaccatttcagagctgggccgaggtgcctatggggtggtggagaag
gtgcggcatgcccagagtggcaccatcatggccgtgaagcgcatccgagccaccgtgaac
tctcaggagcagaagcgcctgctcatggacctggatgtcaacatgcgcacagtggactgt
ttctataccgtcaccttctacggggccctctttagagagggagatgtgtggatctgcatg
gagctcatggacacgtccctggacaagttctatcggaaggtgctagacaagggcatgacg
attccagaagacattcttggggagatcgctgtgtctatcgtgagggccctggaacatctg
cacagcaagctgtccgtgatccatagagatgtgaagccatccaatgtccttatcaacaag
gagggccacgtgaagatgtgtgactttgggatcagtggttacttggtggattctgtggct
aagacaatggatgctggctgcaaaccctacatggcccccgagagaatcaacccagagctg
aaccagaaaggctacaatgtcaagtctgatgtctggagcctcggcatcaccatgatcgag
atggccattctgcgatttccttacgagtcctgggggacccccttccagcagctgaagcag
gtggtagaagagccgtccccccagctcccagctgaccgtttctcccctgactttgtggac
ttcactgcgcagtgcctgagaaagaaccccgcggaacgcatgagctacctggagctgatg
gagcaccctttcttcacctcgcacaaaaccaagaagactgacatcgctgccttcgtgaag
gagatcctgggagaggactcgtag

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