KEGG   Ovis aries (sheep): 443075
Entry
443075            CDS       T03117                                 
Symbol
HGF
Name
(RefSeq) hepatocyte growth factor isoform X1
  KO
K05460  hepatocyte growth factor
Organism
oas  Ovis aries (sheep)
Pathway
oas01521  EGFR tyrosine kinase inhibitor resistance
oas04010  MAPK signaling pathway
oas04014  Ras signaling pathway
oas04015  Rap1 signaling pathway
oas04020  Calcium signaling pathway
oas04151  PI3K-Akt signaling pathway
oas04510  Focal adhesion
oas05144  Malaria
oas05200  Pathways in cancer
oas05205  Proteoglycans in cancer
oas05208  Chemical carcinogenesis - reactive oxygen species
oas05211  Renal cell carcinoma
oas05218  Melanoma
oas05223  Non-small cell lung cancer
oas05225  Hepatocellular carcinoma
oas05226  Gastric cancer
Brite
KEGG Orthology (KO) [BR:oas00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    443075 (HGF)
   04014 Ras signaling pathway
    443075 (HGF)
   04015 Rap1 signaling pathway
    443075 (HGF)
   04020 Calcium signaling pathway
    443075 (HGF)
   04151 PI3K-Akt signaling pathway
    443075 (HGF)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    443075 (HGF)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    443075 (HGF)
   05205 Proteoglycans in cancer
    443075 (HGF)
   05208 Chemical carcinogenesis - reactive oxygen species
    443075 (HGF)
  09162 Cancer: specific types
   05225 Hepatocellular carcinoma
    443075 (HGF)
   05226 Gastric cancer
    443075 (HGF)
   05218 Melanoma
    443075 (HGF)
   05211 Renal cell carcinoma
    443075 (HGF)
   05223 Non-small cell lung cancer
    443075 (HGF)
  09174 Infectious disease: parasitic
   05144 Malaria
    443075 (HGF)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    443075 (HGF)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and neuropeptides [BR:oas04052]
    443075 (HGF)
   00536 Glycosaminoglycan binding proteins [BR:oas00536]
    443075 (HGF)
Cytokines and neuropeptides [BR:oas04052]
 Cytokines
  Growth factors (RTK binding)
   443075 (HGF)
Glycosaminoglycan binding proteins [BR:oas00536]
 Heparan sulfate / Heparin
  Growth factors/receptors
   443075 (HGF)
SSDB
Motif
Pfam: Kringle Trypsin PAN_1 DUF1986 DUF316 CWC25
Other DBs
NCBI-GeneID: 443075
NCBI-ProteinID: XP_004007855
LinkDB
Position
4:40378050..40465631
AA seq 729 aa
MWVIRLLPVLLLQHVLLHLLLPIAIPYAEGQKKRRNTLHEFKKSAKTTLIKEDPLLKIKT
KKMNTADQCANRCIRNKGLPFTCKAFVFDKARKRCLWFPFNSMSSGVKKEFGHEFDLYEN
KDYIRNCIIGKGGSYKGTVSITKSGIKCQPWNSMIPHEHSFLPSSYRGKDLQENYCRNPR
GEEGGPWCFTSNPEVRYEVCDIPQCSEVECMTCNGESYRGPMDHTETGKICQRWDHQTPH
RHKFLPERYPDKGFDDNYCRNPDGKPRPWCYTLDPDTPWEYCAIKMCAHSTMNDTDVPMQ
TTECIQGQGEGYRGTINTIWNGIPCQRWDSQYPHQHDITPDNFKCKDLRENYCRNPDGAE
SPWCFTTDPNIRVGYCSQIPKCDVSSGQDCYRGNGKNYMGSLSKTRSGLTCSMWDKNMED
LHRHIFWEPDATKLNKNYCRNPDDDAHGPWCYTGNPLIPWDYCPISRCEGDTTPTIVNLD
HPVISCAKTKQLRVVNGIPTRTNVGWMVSLKYRNKHICGGSLIKESWILTARQCFPSRNK
DLKDYEAWLGIHDVHGRGDEKRKQVLNVTQLVYGPEGSDLVLLKLARPAILDDFVSTIDL
PNYGCTIPEKTTCSVYGWGYTGLINSDGLLRVAHLYIMGNEKCSQYHQGKVTLNESEICA
GAENIVSGPCEGDYGGPLVCEQHKMRMVLGVIVPGRGCAIPNRPGIFVRVAYYAKWIHKI
ILTYKAPQS
NT seq 2190 nt   +upstreamnt  +downstreamnt
atgtgggtgatcagacttctgccagtgctgctgctgcagcacgtcctcctccacctcttg
cttcccatcgccatcccctatgcagaaggacagaagaaaagaagaaacacacttcatgaa
ttcaaaaagtcagcaaagactactctaattaaagaggacccattactgaagataaaaaca
aaaaaaatgaacactgcagaccaatgtgccaatagatgtattaggaataaaggacttcca
ttcacttgcaaggcctttgtttttgataaagcaagaaaacgatgcctctggttccctttc
aatagcatgtcaagtggagtaaaaaaagagtttggccatgaatttgacctctatgaaaac
aaagactacattagaaactgtatcattggtaaaggtggtagctacaagggaacggtatct
atcactaaaagtggcatcaaatgccagccctggaattccatgataccacacgaacacagc
tttttgccttcgagctatcggggtaaagacctacaggaaaactactgtcgaaatcctcga
ggggaagaagggggaccttggtgtttcacaagcaatccagaggtacgctacgaagtctgt
gacattcctcagtgttcagaagttgaatgcatgacctgcaatggggaaagttaccgaggt
cccatggatcacacagaaacaggcaagatttgtcagcgctgggatcatcagacaccacac
cggcacaaattcttgccagaaagatatcccgacaagggctttgatgataattattgccgc
aatcctgatggcaagccgaggccatggtgctatactcttgaccctgacaccccctgggag
tactgtgcaattaaaatgtgcgcccacagtactatgaatgacacagatgtccctatgcaa
acaactgaatgcattcaaggtcaaggagaaggttaccggggcaccatcaataccatttgg
aatggaattccctgtcagcgttgggattcccagtatcctcaccagcatgacattactcct
gacaatttcaagtgcaaggacctaagagaaaattattgccgaaatccagatggggctgag
tcaccgtggtgttttaccactgatccaaacatccgagttggctactgctcccaaattcca
aaatgtgacgtgtcaagtggacaagattgttatcgtgggaatggcaaaaattatatgggc
agtttatccaaaacacgatctggactaacatgttcgatgtgggataagaacatggaagac
ttacaccggcatatcttctgggaaccagatgctactaagctgaataagaattactgtcgg
aatcctgatgacgatgcccatggtccctggtgttacacagggaatcctctcattccttgg
gattattgccctatttctcgttgtgagggggataccacacctacaatagtcaatttagac
catcctgtaatatcttgcgccaaaacaaaacaattgcgagttgtaaatggaattccaaca
cgaacaaatgtaggatggatggttagtttgaaatacagaaataaacatatctgcggagga
tcattgataaaggaaagttggattcttactgcaagacagtgtttcccttctcgaaacaaa
gacttgaaagattatgaagcttggcttggaattcatgatgtccatgggagaggagacgag
aaacgcaaacaggttctaaatgttacccaactggtatatgggcctgaaggatcagatctg
gtattactgaagcttgctaggcctgctattttggatgattttgttagtacaattgattta
cctaattatgggtgcacaattcctgaaaaaaccacttgcagtgtttatggctggggctac
actggattgatcaactccgatggcctactacgagtagcacatctctatataatggggaat
gagaaatgcagccaatatcatcaagggaaggtgactctgaatgagtctgaaatatgtgct
ggagctgaaaatattgtatcaggaccatgtgagggagattatggtggcccacttgtttgt
gaacaacataaaatgagaatggttcttggtgtcattgttcctggtcgtggctgtgccatt
ccaaatcgtcctggtatttttgtccgagtggcatattatgcaaaatggatacacaaaatt
atattaacgtataaggcaccacaatcgtag

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