Ovis aries (sheep): 443076
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Entry
443076 CDS
T03117
Symbol
MET
Name
(RefSeq) hepatocyte growth factor receptor precursor
KO
K05099
proto-oncogene tyrosine-protein kinase Met [EC:
2.7.10.1
]
Organism
oas
Ovis aries (sheep)
Pathway
oas01521
EGFR tyrosine kinase inhibitor resistance
oas04010
MAPK signaling pathway
oas04014
Ras signaling pathway
oas04015
Rap1 signaling pathway
oas04020
Calcium signaling pathway
oas04151
PI3K-Akt signaling pathway
oas04360
Axon guidance
oas04510
Focal adhesion
oas04520
Adherens junction
oas05100
Bacterial invasion of epithelial cells
oas05144
Malaria
oas05200
Pathways in cancer
oas05202
Transcriptional misregulation in cancer
oas05205
Proteoglycans in cancer
oas05206
MicroRNAs in cancer
oas05208
Chemical carcinogenesis - reactive oxygen species
oas05211
Renal cell carcinoma
oas05218
Melanoma
oas05223
Non-small cell lung cancer
oas05225
Hepatocellular carcinoma
oas05226
Gastric cancer
oas05230
Central carbon metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
oas00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
443076 (MET)
04014 Ras signaling pathway
443076 (MET)
04015 Rap1 signaling pathway
443076 (MET)
04020 Calcium signaling pathway
443076 (MET)
04151 PI3K-Akt signaling pathway
443076 (MET)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
443076 (MET)
04520 Adherens junction
443076 (MET)
09150 Organismal Systems
09158 Development and regeneration
04360 Axon guidance
443076 (MET)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
443076 (MET)
05202 Transcriptional misregulation in cancer
443076 (MET)
05206 MicroRNAs in cancer
443076 (MET)
05205 Proteoglycans in cancer
443076 (MET)
05208 Chemical carcinogenesis - reactive oxygen species
443076 (MET)
05230 Central carbon metabolism in cancer
443076 (MET)
09162 Cancer: specific types
05225 Hepatocellular carcinoma
443076 (MET)
05226 Gastric cancer
443076 (MET)
05218 Melanoma
443076 (MET)
05211 Renal cell carcinoma
443076 (MET)
05223 Non-small cell lung cancer
443076 (MET)
09171 Infectious disease: bacterial
05100 Bacterial invasion of epithelial cells
443076 (MET)
09174 Infectious disease: parasitic
05144 Malaria
443076 (MET)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
443076 (MET)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
oas01001
]
443076 (MET)
Enzymes [BR:
oas01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
443076 (MET)
Protein kinases [BR:
oas01001
]
Receptor tyrosine kinases (RTK)
MET family
443076 (MET)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
TIG
Pkinase
Sema
PSI
Kinase-like
Pkinase_fungal
Linker_histone
Motif
Other DBs
NCBI-GeneID:
443076
NCBI-ProteinID:
NP_001104541
UniProt:
Q09YI9
LinkDB
All DBs
Position
4:complement(53094867..53211758)
Genome browser
AA seq
1384 aa
AA seq
DB search
MKAPAVLAPGILVLLFTFVQKSNGECKEALVKSRMNVNMQYQLPNFTAETSIRNVVLHKH
HIYLGAINYIYVLNDKDLQKVAEYKTGPVLEHPDCFPCQDCSHKANLSGGVWKDNINMAL
LVDTYYDDQLISCGSVHRGTCQRHVLPPNNTADIESEVHCMYSPQEDEETNQCPDCVVSA
LGTKVLLSEKERFINFFVGNTINSSYFPDHSLHSISVRRLKETQDGFKFLTDQSYIDVLP
ELQDSYPIKYVHAFESNHFIYFLTVQRETLDAQTFHTRIIRFCSADSGLHSYMEMPLECI
LTEKRRKRSTKQEVFNILQAAYVSKPGAQLARQIGANLNDDILYGVFAQSKPDSSEPMNR
SAVCAFPVKYVNEFFNKIVNKNNVRCLQHFYGPNHEHCFNRTLLRNSSGCEVRNDEYRTE
FTTALPRIDLFMGQFNQVLLTSISTFIKGDLTIANLGTSEGRFMQVVVSRSGSLTPHVNF
PLDSHPVSPEVVVEHPLNQNGYTLVVTGKKITKIPLNGLGCEHFQSCSQCLSAPSFVQCG
WCHDKCVRLEECPSGRWTQETCLPTIYKVFPTSAPLEGGTTLTVCGWDFGFKRNNKFDLK
KTRVLLGNESCTLTLSESTTNMLKCTVGPATNEHFNMSIVISNSRGSVQYSMFSYVDPII
TSISPNYGPKTGGTLLTLTGKHLNSGNSRHISIGGKTCTLKSVSYSILECYTPAQSAPTE
FSVKLKIDLANREVNSFIYREDPIVYEIHPTKSFISGGSTITGVGKNLNSVSIIRMVINV
HEAGKNFTVACQHRSNSEIICCTTPSLQQLNLQLPLKTKAFFMLDGIHSKYFDLIYVHNP
VFKPFEKPVMISIGNENVLEIKGNDIDPEAVKGEVLKVGNKSCENIQSHSEAVLCTVPND
LLKLNSELNIEWKQAISSTVLGKVIVQPDQNFTGLIVGVVSVSIILLLLLGLFLWLKKRK
QIKDLGSELVRYDARVHTPHLDRLVSARSVSPTTEMVSNESVDYRATFPEDQFPNSSQNG
SCRQVQYPLTDLSPILTSGDSDISSPLLQNTVHIDLSALNPELVQAVQHVVIGPSSLIVH
FNEVIGRGHFGCVYHGTLLDNDDKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNV
LSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMEYLASKK
FVHRDLAARNCMLDEKFTVKVADFGLARDVYDKEYYSVHNKTGAKLPVKWMALESLQTQK
FTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDITVYLLQGRRLLQPEYCPDPLYEVMLKC
WHPKAELRPSFSELVSRIAAIFSAFIGEHYVHVNATYVNVRCVAPYPSLLSSQENVSGED
DDDT
NT seq
4155 nt
NT seq
+upstream
nt +downstream
nt
atgaaggcccctgctgtgctcgcacctggcattcttgtgcttctgtttaccttcgtgcag
aagagcaatggggagtgtaaagaggcactagtaaagtccaggatgaatgtgaacatgcaa
tatcagcttcctaacttcactgcagaaacatccatccggaatgttgttttgcacaaacat
cacatttacctcggtgccattaactacatttacgttttaaatgacaaagaccttcagaag
gttgctgagtacaagactgggcctgtgctggaacacccagattgtttcccatgtcaggac
tgcagccacaaagccaatttatcaggtggtgtttggaaagataacatcaacatggctctg
cttgttgacacgtactatgatgatcaactcattagctgtggcagtgtccacagagggacc
tgccagcggcacgtcctgccacccaacaatactgcagacatagagtcggaagtccactgc
atgtattctcctcaggaagacgaagagaccaaccagtgtcctgactgtgtggtgagtgcc
ctgggaaccaaagtcctactgtctgagaaggagcgattcatcaacttcttcgtgggcaat
accataaattcttcttactttccagatcattcattgcactcgatatcggtgagaaggcta
aaggaaacgcaagatggttttaagtttttgacagaccaatcctatattgatgttctacct
gagcttcaagattcctaccccattaagtatgtccacgcctttgaaagcaaccattttatt
tactttttgacagtccaacgggaaactctagatgctcagacttttcacacaaggataatc
aggttttgttccgcagactctggattgcattcatacatggaaatgcctctggagtgtatt
ctgacagaaaagagaagaaagagatccacaaagcaggaagtgtttaatattctccaagct
gcatatgtcagtaagcctggggctcagcttgctaggcaaataggtgccaacctgaatgat
gacattttgtacggggtgtttgcacaaagcaagccagattcctcagaaccaatgaatcgc
tctgctgtctgtgcattccctgtcaaatatgtcaatgagttcttcaacaagatcgtcaac
aaaaacaatgtgagatgtctccagcacttttatggccccaaccatgaacactgcttcaat
aggacacttttgagaaattcatcaggatgtgaagtgcgcaatgatgaatatcgaacagag
tttaccacagctttgccgcgcattgacttattcatgggccagttcaaccaagtcctctta
acatctatatccacctttatcaaaggagatctcaccatcgctaatctcgggacgtcagaa
ggtcgattcatgcaggttgtggtttctcgatcaggatcattaactcctcacgtgaatttt
ccgctggattcccaccctgtgtctccagaagtggttgtggagcacccgctaaaccagaat
ggctatacactggttgtcactgggaagaagatcaccaagatcccgctgaatggcctgggc
tgtgaacatttccagtcctgcagtcagtgcctctccgccccttcctttgtgcagtgtggc
tggtgccatgataaatgtgtgcgattggaggaatgccccagtggaaggtggactcaagag
acctgtctgccaacaatctacaaggtttttccaactagtgccccccttgaaggagggaca
acactgactgtttgtggctgggactttggattcaagaggaataataaatttgacttgaag
aaaaccagagttctccttggaaatgagagctgcaccttaaccttaagtgagagcacaaca
aacatgttgaaatgcacagttggtcctgcaacgaatgaacatttcaatatgtccatagtt
atttcaaacagtcgtgggtcagtacagtatagtatgttttcctatgtggatcctataata
acaagtatttctccaaattatggtccaaaaactggtggcactttacttacattaactgga
aagcacctaaacagtggaaattcaagacacatttcaattggtggaaaaacatgtacttta
aaaagtgtttcatatagtattctcgaatgttataccccagcccaaagtgctccaactgag
ttttctgttaaattgaaaattgacttagccaaccgagaggtgaacagcttcatttaccgg
gaagaccccattgtctatgaaatacatcccaccaaatcttttattagtggtgggagtaca
ataacaggtgttggaaaaaacctgaattcagttagtatcataaggatggtaataaatgtg
catgaagccggaaagaactttacagtggcatgtcaacatcgctctaattcagagataatc
tgctgtacaactccttcactacaacagctgaacctacaactccccctgaaaaccaaagcc
tttttcatgttagatgggatccattccaaatactttgatctcatttatgtacataatcct
gtgtttaagccttttgaaaagccagtgatgatctcaataggcaatgaaaatgtactggaa
attaagggaaatgatattgaccctgaagcagttaaaggggaggtgttaaaagttggaaat
aagagctgtgaaaatatacagtcacattctgaagctgtattatgtacggtccccaatgac
ctgctgaaattgaacagcgaactaaatatagagtggaagcaagcaatttcttcaactgtt
cttggaaaagtgatagttcaaccagatcagaatttcacaggattgattgttggtgttgtc
tcagtatcaataatactcttactgttactcgggcttttcctgtggctgaaaaaaaggaag
caaattaaagatctgggcagtgaattagttcgctatgatgcaagagtacacactccacat
ttggataggcttgtcagtgcccgaagtgtaagcccaactacagaaatggtttccaatgaa
tctgtagactaccgagctacttttccagaagaccagtttcctaattcatctcagaatggg
tcatgcagacaagtgcagtatcctctgacagatctatcccccatcttaactagtggggac
tctgatatatccagtccattactgcaaaataccgtccacatcgacctcagtgctctaaat
ccagagctggtccaggcagttcagcacgtagtaattgggccgagcagtctgattgtacat
ttcaatgaagtcataggaagaggacattttggttgtgtatatcatggaactttgttggac
aacgatgataagaaaattcactgtgctgtgaaatccttgaatagaatcactgacatagga
gaagtttcccaatttctgactgagggaatcatcatgaaagattttagtcatcccaatgtt
ctctcgcttttgggaatctgccttcgaagtgaggggtctccactggtggtcctaccatac
atgaaacacggggatcttcgaaatttcattagaaatgagactcataacccaactgtaaaa
gatcttattggctttggtcttcaagtagccaaaggcatggaatatcttgcaagcaaaaag
tttgtccacagagacttggctgcaagaaactgtatgctggatgaaaaattcaccgtcaag
gttgctgattttggtcttgccagagacgtgtatgataaggaatactatagcgtacacaac
aaaacaggtgcaaaactgccagtgaaatggatggctttagaaagcctgcagactcagaaa
tttaccaccaagtcagatgtgtggtcctttggcgtgctcctctgggaactgatgacaaga
ggagcaccaccttatcctgacgtcaacacctttgacataacagtttacttgttgcaagga
agaaggctcctacaacctgaatactgcccagatcccttgtatgaagtgatgctgaaatgc
tggcaccctaaagctgaattgcgcccatccttttctgaactggtctccaggatagccgcg
atattctccgctttcattggggagcactatgtccatgtgaatgctacttacgtgaacgtc
agatgtgttgccccatatccttctctgttgtcatcacaagagaatgtcagtggcgaggat
gatgatgacacatga
DBGET
integrated database retrieval system