Ovis aries (sheep): 443087
Help
Entry
443087 CDS
T03117
Symbol
KDR
Name
(RefSeq) vascular endothelial growth factor receptor 2 precursor
KO
K05098
kinase insert domain protein receptor [EC:
2.7.10.1
]
Organism
oas
Ovis aries (sheep)
Pathway
oas01521
EGFR tyrosine kinase inhibitor resistance
oas04010
MAPK signaling pathway
oas04014
Ras signaling pathway
oas04015
Rap1 signaling pathway
oas04020
Calcium signaling pathway
oas04151
PI3K-Akt signaling pathway
oas04370
VEGF signaling pathway
oas04510
Focal adhesion
oas05205
Proteoglycans in cancer
oas05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
oas00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
443087 (KDR)
04014 Ras signaling pathway
443087 (KDR)
04015 Rap1 signaling pathway
443087 (KDR)
04370 VEGF signaling pathway
443087 (KDR)
04020 Calcium signaling pathway
443087 (KDR)
04151 PI3K-Akt signaling pathway
443087 (KDR)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
443087 (KDR)
09160 Human Diseases
09161 Cancer: overview
05205 Proteoglycans in cancer
443087 (KDR)
09166 Cardiovascular disease
05418 Fluid shear stress and atherosclerosis
443087 (KDR)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
443087 (KDR)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
oas01001
]
443087 (KDR)
09183 Protein families: signaling and cellular processes
04090 CD molecules [BR:
oas04090
]
443087 (KDR)
Enzymes [BR:
oas01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
443087 (KDR)
Protein kinases [BR:
oas01001
]
Receptor tyrosine kinases (RTK)
VEGFR family [OT]
443087 (KDR)
CD molecules [BR:
oas04090
]
Proteins
443087 (KDR)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Ig_3
VEGFR1-3_N_Ig-like
I-set
Pkinase
Ig_2
VEGFR-1-like_Ig-like
ig
Ig_VEGFR-1-like_5th
VEGFR-2_TMD
V-set
C2-set_2
Ig_4
Haspin_kinase
BppU_N
Motif
Other DBs
NCBI-GeneID:
443087
NCBI-ProteinID:
NP_001265494
UniProt:
W5NSG6
LinkDB
All DBs
Position
6:complement(71265734..71315329)
Genome browser
AA seq
1356 aa
AA seq
DB search
MESKALLALALWLCVETRAASVGFSSVSLDPPRLSIQKDIVTIMANTTLQITCRGQRDLR
WLWPNNQSSSEKRVEVTDCSDGFFCKMLTISEVIGNDTGAYKCFYQDIDMASTVYVYVQD
YRSPFIASVSDQHEVVYITENKNKTVVIPCLGTVSDLNVSLCARYPEKRFVPDGNRISWD
SKKGFSIPSYMISYAGVVFCEAKINDESYQSIMYIIVVIGYKIYDVVLSPSHGVELSVGE
RLILNCTARTELNVGIDFHWEYPSLKHQHKKLINRDLKTQSGTEMKKFLSTLTIDGVTRS
DQGWYICAASSGLMTKKNSTFVRVHEKPFVAFSSGMESLVEATVGERVRVPVKYLGYPPP
EIKWYKNGKPIESNHTVKVGHVLTIMEVSEKDTGNYTVILTNPISKEKQSHMVSLVVNVP
PQIGEKSLLSPVDSYQYGTSQTLTCTVYAVPPPSHIRWYWQLETECTYQPTLTALTTNPY
TCKEWRNVEDFQGGNKIEVNKNQIALIEGRNKTVSTLVIQAANVSALYKCEAVNKAGRGE
RVISFHVTRGPEITLQPGTQPTEQESVSLWCSADRTMFENLTWYKLGPQVLPIHMGDLPT
PVCKNLDALWKMNATMISNSTNDILIMELQNASLQDQGDYVCFAQDRKTKKRHCVARQLT
VLERMAPMITGNLENQTTSIGETIEVSCTASGNPSPQITWFKDNETLVEDSGIVLKDGNR
NLTIRRVRKEDEGLYTCQACSVLGCAKVEAFFIVEGAQEKTNLEVIILVGTAVIAMFFWL
LLVIVLRTVKRANGGELKTGYLSIVMDPDELPLDEHCERLPYDASKWEFPRDRLKLGKPL
GRGAFGQVIEADAFGIDKTATCKTVAVKMLKEGATHSEHRALMSELKILIHIGHHLNVVN
LLGACTKPGGPLMVIVEFCKFGNLSTYLRSKRNEFVPYKTKGAQFRQGKEYVGEITMDPK
RRLDSITSSQSSASSGFVEEKSLSDVEEEEVSEDLYKNFLTLEHLICYSFQVAKGMEFLA
SRKCIHRDLAARNILLSEKNVVKICDFGLARDIYKDPDYVRKGDARLPLKWMAPETIFDR
VYTIQSDVWSFGVLLWEIFSLGASPYPGVKIDEEFCRRLKEGTRMRAPDYTTPEMYQTML
DCWHGDPNQRPTFSELVEHLGNLLQANAQQDGKDYIVLPISETLSMEEDSGLSLPTSPVS
CMEEEEVCDPKFHYDNTAGISQYLQNSKRKSRPVSVKTFEDIPLEEPEVKVIPDDSQTDS
GMVLASEELKTLEDRTKLAPSFSGLMPSKSKESVASEGSNQTSGYQSGYHSDDTDTTVYS
SEEAELLKLMEIGPQVGSAAPILQPDSGTTLSSPPV
NT seq
4071 nt
NT seq
+upstream
nt +downstream
nt
atggagagcaaggcgctgctggctcttgctctgtggctctgcgtggagacccgggctgcc
tctgtgggtttttctagtgtttcccttgatccacccaggctcagcatccaaaaagacata
gttacaattatggctaacacaacgcttcagattacttgcaggggtcagagggacttgcgc
tggctctggcccaacaatcagagcagctctgagaaaagagtggaggtcacagattgcagt
gatggcttcttctgtaagatgctcacaatttcagaagtgattggaaatgatactggagcc
tacaagtgcttctaccaggacattgacatggcctccactgtttatgtgtatgttcaagat
tacaggtctccatttattgcttctgttagcgaccagcatgaagttgtgtacatcactgag
aacaaaaacaaaactgtggtgattccatgtttggggactgtttcagacctcaatgtgtca
ctttgtgcaaggtatcccgaaaaaagatttgttcctgatggtaacagaatttcctgggac
agcaagaaaggcttcagtattcccagctatatgatcagttatgctggcgtggtcttctgt
gaagcaaaaatcaatgatgaaagttaccagtctattatgtacataattgtggttataggg
tacaagatttatgatgtggttctgagcccctctcatggagtcgagctgtctgttggagag
aggctcatcttaaactgtacggcaagaactgagctaaatgtggggattgacttccactgg
gaatacccttctttgaagcatcagcataaaaaacttataaaccgggacctaaaaacccag
tctgggactgaaatgaagaagtttttgagcaccttgactatagatggtgtaacccggagt
gaccaggggtggtatatctgtgcagcttccagtgggctgatgaccaagaagaacagcacg
ttcgtccgggtacatgaaaagccgtttgttgctttcagtagtggcatggaatccttggtg
gaagctaccgtgggggaacgtgtcagagtccctgtcaagtaccttggttaccctcctcca
gaaataaaatggtataaaaatggaaaacccattgagtccaatcacacagttaaagtgggg
catgtgctgactattatggaagtgagtgaaaaagatacaggaaattacactgtcattctt
accaatcccatttcaaaggagaaacagagccacatggtatctctggtggtgaatgtccca
cctcagattggtgagaaatctctgctgtctcccgtggactcttaccagtacggcacttcc
cagacactgacgtgcacggtctacgccgttcctcccccaagtcacattcgctggtactgg
cagctggagacagagtgcacctaccagcccaccctcactgccttaacgacaaacccgtac
acttgtaaggaatggagaaacgtggaggacttccaggggggaaacaaaatcgaagtcaat
aaaaatcagattgccctaattgaaggaagaaacaaaactgtaagtactcttgttatccaa
gcggccaatgtgtccgctttgtataaatgtgaagcagtgaacaaagctggaagaggagag
agggttatctccttccacgtgaccaggggtcctgaaatcacgttgcaacccggcacccag
cccaccgagcaggagagtgtgtctctgtggtgctccgcggacagaactatgtttgagaac
ctcacgtggtacaaactcggcccacaggtcctgcccatccacatgggcgatttacccaca
cctgtctgcaagaacttggatgctctttggaaaatgaatgccaccatgatctctaacagc
acaaatgacatcttgatcatggagctgcagaatgcatccttgcaggaccaaggagactat
gtctgctttgctcaggacaggaagactaagaaaagacattgtgtggccaggcagctcaca
gtcctagagcgcatggcacccatgatcacaggaaacctggagaatcagacgacaagtatt
ggtgaaaccatcgaagtttcctgcacagcatctgggaatccctctccacagattacatgg
tttaaagataatgaaacgcttgtggaggactcaggcattgtgctaaaagatgggaaccga
aacctaactatccgcagagtgaggaaggaggatgaaggcttgtacacctgccaggcgtgc
agtgttctggggtgtgcaaaagtggaggcatttttcatagtagaaggtgcccaggaaaag
acaaacttggaagtcattattctagtaggcactgcagtgattgccatgttcttctggcta
cttcttgtcatcgttctacggaccgttaagcgggccaatggaggggaactgaagacgggc
tacttatccatcgtcatggatccagacgaactccccttggatgagcactgtgaacgcctg
ccttatgatgccagcaaatgggaattccccagagaccggctgaaactaggtaagcctctt
ggtcgtggtgcctttggacaagtgattgaagcagatgcctttggaattgacaagacagca
acctgcaagacagtggctgtcaaaatgttgaaagaaggagcaacacacagtgaacaccga
gccctcatgtctgaactcaagatccttattcatattggccaccatctcaacgtggtcaat
cttcttggtgcctgtaccaagccaggggggccactcatggtcattgtggaattctgcaag
tttggaaacctgtcaacttacttaagaagcaagagaaatgaatttgtcccctacaagacc
aaaggggcacagttccggcaagggaaagaatacgttggggagatcaccatggatcctaaa
cgccgcttggacagcatcaccagcagccagagctcagccagctctgggtttgttgaggag
aagtccctcagtgatgtggaggaggaggaagtttctgaagatctgtacaagaacttcctg
accttggagcatctcatctgttacagcttccaagtggctaagggcatggagtttttggca
tcacggaagtgtatccacagggacctggcagcgcgaaacatcctcttgtcggaaaagaac
gtggttaaaatctgtgactttggcttggcccgggatatttataaagacccagattatgtc
agaaaaggagatgctcgcctccctttgaagtggatggccccagaaacgatttttgaccga
gtgtacacaattcagagtgacgtgtggtcttttggtgtcctgctctgggaaatattttcc
ttaggtgcttctccgtatcctggagtcaagattgatgaggaattttgtaggcgactgaaa
gaaggaactagaatgagagcccctgattacaccacaccagaaatgtaccagaccatgctt
gattgctggcatggggatcccaatcagagacccacattttcagagctggtggagcatctg
ggaaatctgttacaagctaatgctcaacaggatggcaaagactacattgttcttcccata
tcagagactttgagcatggaagaggattcgggactctctctgcctacctcacctgtttcc
tgtatggaggaagaggaagtatgtgaccccaaattccattatgacaacacagcaggaatc
agtcagtatctgcagaacagtaagcgaaagagccggcccgtcagtgtaaaaacatttgaa
gatatcccgttggaagaaccagaagtaaaagtcatcccagatgacagccagacggacagt
ggtatggttcttgcatctgaagagctgaaaaccctggaagacagaaccaagttagcccca
tcttttagtggactgatgcccagcaaaagcaaggagtctgtggcatccgaaggctcaaac
cagacaagcggctaccagtcgggataccattctgatgacacggacaccactgtgtactcc
agcgaggaggctgaacttttaaagctgatggagattggaccgcaggttggcagtgcagct
ccgattctccagcctgactctgggaccacactgagctctcctccagtttaa
DBGET
integrated database retrieval system
