Ovis aries (sheep): 443334
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Entry
443334 CDS
T03117
Symbol
MYLK
Name
(RefSeq) myosin light chain kinase, smooth muscle isoform X2
KO
K00907
myosin-light-chain kinase [EC:
2.7.11.18
]
Organism
oas
Ovis aries (sheep)
Pathway
oas04020
Calcium signaling pathway
oas04022
cGMP-PKG signaling pathway
oas04270
Vascular smooth muscle contraction
oas04371
Apelin signaling pathway
oas04510
Focal adhesion
oas04517
IgSF CAM signaling
oas04611
Platelet activation
oas04810
Regulation of actin cytoskeleton
oas04921
Oxytocin signaling pathway
oas04971
Gastric acid secretion
Brite
KEGG Orthology (KO) [BR:
oas00001
]
09130 Environmental Information Processing
09132 Signal transduction
04371 Apelin signaling pathway
443334 (MYLK)
04020 Calcium signaling pathway
443334 (MYLK)
04022 cGMP-PKG signaling pathway
443334 (MYLK)
09133 Signaling molecules and interaction
04517 IgSF CAM signaling
443334 (MYLK)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
443334 (MYLK)
09142 Cell motility
04810 Regulation of actin cytoskeleton
443334 (MYLK)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
443334 (MYLK)
09152 Endocrine system
04921 Oxytocin signaling pathway
443334 (MYLK)
09153 Circulatory system
04270 Vascular smooth muscle contraction
443334 (MYLK)
09154 Digestive system
04971 Gastric acid secretion
443334 (MYLK)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
oas01001
]
443334 (MYLK)
Enzymes [BR:
oas01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.18 myosin-light-chain kinase
443334 (MYLK)
Protein kinases [BR:
oas01001
]
Serine/threonine kinases: CAMK group
MLCK family
443334 (MYLK)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
I-set
Ig_3
ig
Ig_2
Pkinase
23ISL
V-set
PK_Tyr_Ser-Thr
C2-set_2
fn3
BiPBP_C
Ig_4
Ig_DSCAM-DSCAML_C
Ig_ADGRF3
Invasin_D3
Kinase-like
RIO1
DUF5898
Kdo
AvrM_N
Pur_ac_phosph_N
Motif
Other DBs
NCBI-GeneID:
443334
NCBI-ProteinID:
XP_011951262
LinkDB
All DBs
Position
1:complement(188839645..189119722)
Genome browser
AA seq
2131 aa
AA seq
DB search
MRGTMCLPGQPGGTTAPKTMGDVKLAAQTHVSKTSLTVDHSRVSSMPLTEAPAFTLPPRN
LCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITGGGRFLLDCGTRGTFSLLIHAVREEDK
GRYTCEATNGSGARQVTVELTVEGSFVKKPGQPVVSKALGDRLAAPAMETRPSIWGECPP
KFATKLGRAVVREGQMGRFSCKITGRPQPQVTWLKGDVPLQPSARVSMSEKNGMQVLEIH
DVTRDDVGVYTCMVVNGSGKASMSAELSIQGLDNSDRSLVRGTKVAGTDIRKEVTQGSKP
DGLAAAAEDKNRPSTQQGGSLTWATGSQPQPPRESDLEPLGDSPRKGQRTPVLQKTSSTI
TLQAAKVQLEPRAPVPGTPCPSREEREEPAVAAPDALPTRRSGLGSQDTMGKVATRKVPM
ESQRDTTFPKFENKPQSQEVSEDQPVEFRCEVSGIPKPEVTWFLDGVPVRSREGSIEVYE
AGGKHYLCLWRARAQDSGSYSCTAANVRGQASCHWSLLVKKPAVVEVAPSFSSALKDCTV
VEGQDFVLQCSVKGTPLPRITWLLNGQPIQYARSTCEAGVAELHIQDTLPEDDGTYTCLA
ENTAGQVSCSARVTVQEKKSEEKSERLLPAAPSKPAAPLFLQGLSDLHVMDGSQVTMTVR
VSGNPPPEVIWLHDGTEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVR
TQAVLTVQEPQDGTQPWFISKPRSVTACLGQSVLISCAIAGDPFPTVHWLRDGKALSRDT
GHFEVLQNEDVFTLVLKNVQPWHAGQYEILLKNRVGQCSCQVSLMLQSSPARVVLRGREP
ASCEGLCGRGAGADGGGGGDGYGSLRPGWPVARGQGAPAEDDGEDVRGVLKRRVETRQHT
EEAVRQQEVEQLDFRDLLGKKVSTKTLSEEDLKEIPAEQLDFRDLLGKKVSTKTLSEEDL
KEIPAEQMDFRANLQRQVKPKTLSEEERKVHGPQQVDFRSVLAKKGTPKTPVPEKVPPPK
PATPDFRSVLGSKKKLPTENGSNNTEALNAKAAEGPKPVGNAQPSGFLKPVGNAKLADTP
KPLSSTKPAEIPKPLGNVKPAETPKPLGNVKPSETPKPLGNVKPAETPKPLGNVKPAETP
KPLGNVKPSETPKPLGNVKPAETPKPLGNVKPAETPKPLGNVKPAETPKPLGNVKPAETP
KPLGNIKPAETPKPLGNAKPAETPKPLSNVKPAETPKSVGNTKPAETSKPLDNTKPAEAP
KPLGNAKPAEIPKPTGKEELKKEVKNDVNCKKGHAGATDSEKRPESRGTAPTFEEKLQDL
HVAEGQKLLLQCRVSSDPPATVTWTLNGKTLKTTKFIVLSQEGSLCSVSIEKALPEDRGL
YKCVAKNSAGQAESSCQVTVDVPDAPASENAKAPEMKARRPKSSLPPVLGTESDATVKKK
PAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVAGTQPITCTWMKFRKQIQDSEHIK
VENSEQGSKLTIRAACQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRS
SSLTLSWYGSSYDGGSAVQSYSVEIWDSVDKTWKELATCRSTSFNVQDLLPDREYKFRVR
AINVYGTSEPSQESELTALGEKPEEEPKDEVEVSDDDEKEPEVDYRTVTVNTEQKVSDFY
DIEERLGSGKFGQVFRLVEKKTGKIWAGKFFKAYSAKEKENIRQEISIMNCLHHPKLVQC
VDAFEEKANIVMVLEIVSGGELFERIIDEDFELTERECIKYMKQISEGVEYIHKQGIVHL
DLKPENIMCVNKTGTRIKLIDFGLARRLENAGSLKVLFGTPEFVAPEVINYEPIGYATDM
WSIGVICYILVSGLSPFMGDNDNETLANVTSATWDFDDEAFDEISDDAKDFISNLLKKDM
KNRLNCTQCLQHPWLMKDTKNMEAKKLSKDRMKKYMARRKWQKTGNAVRAIGRLSSMAMI
SGLSGRKSSTGSPTSPLNAEKLESEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSA
ARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAV
NSLGEATCTAELIVETMEEGEGEGGEEEEEE
NT seq
6396 nt
NT seq
+upstream
nt +downstream
nt
atgaggggaactatgtgccttcctgggcagccaggagggaccactgcccccaagaccatg
ggggatgtgaagctggccgcccagacacacgtttccaaaacctccctcactgtggatcac
tcaagagtcagctccatgcccctgactgaggcccctgctttcactttgccccctcggaac
ctctgcatcaaggaaggagccactgccaagtttgaagggagggttcggggctacccagag
ccccaagtgacatggcacagaaacggacaacccatcaccggtgggggccgcttcctgctg
gactgtggtacccgggggactttcagccttttgattcatgctgtgcgtgaagaggacaag
ggaaggtatacctgtgaagccactaacggtagtggtgcccgccaggtgacagtggagttg
acagtagaagggagctttgtgaagaagcctggccagcctgttgtttccaaagccttgggg
gacagacttgcagcccctgccatggagacccgtcctagcatctggggagaatgtccacca
aaatttgctaccaagctgggccgagcggtggtcagagaaggacagatggggcggttctcc
tgcaagatcactggccggccccagccacaggtcacgtggctcaagggagatgttcccctg
cagcccagtgctcgtgtgtctatgtccgagaagaacgggatgcaagtcctagaaatccac
gacgtcacccgagatgacgtgggagtatacacgtgcatggtggtgaacgggtcagggaag
gcctccatgtctgctgagctctccatccaaggtttggacaattccgataggtcacttgtg
agaggaacaaaggtggccggtacagacatcaggaaggaagtcactcaggggtccaaaccg
gatggcctggcggctgctgccgaagataaaaaccgtcccagcacccagcaaggaggctcc
ctgacctgggccacagggagccagcctcaacctcccagggaatctgacctggagccgctg
ggggactcccccagaaagggccagaggacccccgtcctgcagaagacctccagcaccatc
accctgcaggcggcaaaagtccagctggagcccagagctccagtcccaggcaccccctgt
ccctccagagaagagagggaggagccagctgtggccgctccagacgccctccccaccagg
cggtcaggcctgggaagccaggacaccatgggcaaggttgctaccaggaaggtccccatg
gagagccagagggacaccacgtttcccaaatttgagaacaagccccagagccaggaggtc
agtgaagatcagccagtcgagtttagatgcgaggtttcagggatcccaaaacctgaagtg
acctggttcctggacggtgtccccgtgaggagtcgagagggcagcatcgaggtttatgaa
gctggggggaagcattacctctgcctgtggagagcccgggcccaggacagcgggagctac
agctgcacagccgccaatgtccgaggccaggcgtcctgtcactggagcctcctggtgaaa
aagccagccgtggtggaggtggccccatcattctccagtgccctgaaggactgcactgtc
gttgagggtcaggactttgtgctgcaatgctcagtgaaggggaccccattgcctcgaatc
acttggctgctcaatggacagcccatccagtatgcccgctccacctgcgaggctggcgtg
gccgagctccacatccaggacaccctcccagaggacgatggcacctacacctgtctggcc
gagaacaccgcggggcaggtgtcctgcagcgcccgcgtcactgtccaggagaagaagagt
gaggagaagagtgagcgcctcctgcccgcggcccccagcaagcccgccgcgcccctcttc
ctgcagggcctctctgacctccacgtcatggacgggagccaggtcaccatgacagtccgg
gtgtcagggaacccgcccccggaggtcatctggcttcacgacgggactgagatccaggag
tccgaggacttccactttgaacagagaggcactcagcacagcctgtgtatccaggaagtg
ttcccggaggacacgggcacttacacctgtgaggcctggaacagcgcaggagaggtccgc
acacaggccgtgctcaccgtgcaagagccgcaggatggcacccagccctggttcatcagc
aagccccgctcggtgactgcctgcctgggccagagtgtccttatctcctgtgccatagcc
ggcgaccccttccccactgtgcactggctccgagatggcaaagccctctccagagacact
ggccacttcgaggtgctacagaatgaggatgtgttcaccctggttctgaaaaacgtgcag
ccctggcatgccggccagtatgagatcctgctcaagaaccgtgttggtcagtgcagttgc
caggtgtccctgatgctacagagcagcccggccagagtggtcctgcgggggagggagcct
gccagctgcgagggcctctgtggccgaggagctggtgctgatggtggtggtggtggtgac
ggctacgggagcctgaggcctggctggccggtggcgagagggcagggtgcccccgcggaa
gacgacggcgaggacgtgcgtggggtgctcaagaggcgcgtggagacacggcagcacacg
gaggaggccgttcgccagcaggaggtggagcagctggacttccgtgacctcctgggcaag
aaggtgagcaccaagaccttgtctgaagaggacctgaaggagatcccggctgagcagctg
gacttccgcgacctcctgggcaagaaggtgagtacaaagaccttgtctgaagaggacctg
aaggagatcccggctgagcagatggatttccgcgccaacctgcagcggcaggtgaagccg
aagaccctgtcggaggaggagaggaaagtgcatggcccccagcaggtggacttccgctct
gtcttggccaagaaggggactcccaagacccctgtgcctgagaaggtaccccctccaaaa
cctgccaccccagattttcgctcagtgttgggcagtaagaaaaaattaccaacagagaat
ggtagcaataacactgaggccttgaatgccaaggcagcagaaggtcccaagcctgtgggc
aatgcccagccttcagggttcctgaaacccgtgggcaacgccaagctggctgatacccca
aaacccttgagcagcaccaagccagcagagatccccaaacccttgggtaatgtcaagcca
gccgagacccccaaacccttaggtaacgtcaagccatcagagacccccaaacccttgggt
aacgtcaagccagccgagacccccaaacccttgggtaacgtcaagccagccgagaccccc
aaacccttaggtaacgtcaagccatcagagacccccaaacccttgggtaatgtcaagcca
gccgagacccccaaacccttgggtaacgtcaagccagccgagacccccaaacccttgggt
aacgtcaagccagccgagacccccaaacccttgggtaacgtcaagccagccgagaccccc
aaacccttgggtaacatcaagccagccgagacccccaaacccttaggcaacgccaagcca
gccgagacccccaaacccttgagtaatgtcaagccagccgagacccccaaatctgtgggc
aacaccaagccagctgagacctctaaacccttggataacaccaagccagctgaggcccct
aaacccttgggcaatgccaagccagctgaaatccccaaacccactgggaaagaagaactt
aagaaggaggttaagaatgatgtgaactgcaagaagggccatgcaggggccacagacagt
gaaaagagaccagagagccgagggacagccccgacctttgaggagaaactacaagatctc
catgtggcagagggtcagaagctgctgctccagtgcagggtgtcctctgaccccccggcc
accgtcacttggacactgaatggaaagacgctcaagaccaccaagttcatcgtcctctcc
caagaaggctccttgtgctccgtctccatcgagaaggcactgcccgaggacagaggcttg
tacaagtgtgtagccaagaacagtgccggccaggctgagtcctcctgccaagtcaccgtg
gacgttccagatgcccccgccagcgaaaatgccaaggccccggagatgaaagcccggagg
ccgaagagctctcttcctccagtgctaggaacagagagtgatgcaactgtgaaaaagaaa
cctgcccccaagacacctccgaaggcagccatgccgcctcagatcatccagtttcctgag
gaccagaaggtgcgggcaggagagtctgtggagctctttggtaaggtggccggcacccag
cccatcacctgcacctggatgaagttccgaaagcagatccaggacagcgagcacatcaag
gtggagaacagtgagcagggcagcaagctcaccatccgggcggcgtgccaggagcactgc
ggctgctacaccctgctggtggagaacaaactgggcagcaggcaggcccaggtcaacctc
accgtggtggataagccagaccccccagctggcacgccttgtgcctctgacatccgaagc
tcctcgctgaccttgtcctggtacggttcctcgtatgatgggggcagcgctgtacagtca
tacagtgtcgagatctgggactcagtggacaagacgtggaaggaactagccacgtgccgc
agcacttctttcaacgtccaggacctgctgcctgaccgagaatataagttccgtgtgcgt
gcaatcaatgtctatggaactagtgagccaagccaggagtctgaactcacagccttggga
gagaaacctgaagaagagccgaaggacgaagtggaggtgtcagatgatgatgagaaggaa
cctgaggtcgactaccggaccgtcacggtcaataccgagcagaaagtgtccgacttctat
gacatcgaagagagactaggatctgggaaatttggacaggtctttcgacttgtagaaaag
aaaactggaaaaatctgggcagggaaattcttcaaggcttattcggccaaggagaaagag
aacatccgtcaggagatcagcatcatgaactgcctgcaccaccccaagctggtccagtgt
gtggacgccttcgaagagaaggccaacatcgtcatggtcctggagattgtgtctgggggc
gagttgttcgagcgcatcattgatgaggacttcgagctgacggagcgggagtgcatcaag
tacatgaagcagatctcggagggggtggagtacatccacaagcagggcatcgtccacctg
gacctcaagcccgagaacatcatgtgtgtcaacaagacaggcaccaggatcaagctcatc
gacttcggtctggccaggaggttggagaatgcagggtctctgaaggtcctctttggcacc
ccggagttcgtcgcacccgaagtgatcaactacgagcccattggctatgccacggacatg
tggagcatcggggtcatctgctatatcctggtcagtggactgtcccccttcatgggtgac
aatgacaacgaaaccttagccaacgttacctcagccacctgggacttcgacgacgaggcc
tttgatgagatctctgatgacgccaaggattttatcagcaacttgctgaagaaggatatg
aaaaaccgcttgaactgcacccagtgccttcagcatccatggctaatgaaagacaccaag
aacatggaggccaagaaactctccaaggaccggatgaagaagtacatggcaagaaggaaa
tggcagaaaacgggcaatgctgtgagagccatcggaagactgtcctctatggcaatgatc
tcagggctcagtggcaggaaatcctcaacagggtcaccaaccagcccgctcaatgcagaa
aaactagaatctgaagatgtctcccaagctttcctggaggctgttgctgaggagaagccc
catgtaaaaccctacttttccaagaccattcgtgatttagaagttgtggagggaagtgct
gcaagatttgactgcaagattgaaggatacccagaccctgaagtcgtctggttcaaagat
gaccaatcaatccgggagtcccgccacttccagatagactacgacgaggatggaaactgc
tctttaatcattagtgatgtttgcggggatgatgatgccaagtacacctgcaaggctgtc
aacagtctcggagaagccacctgcacagcagagctcatcgtggaaaccatggaggaagga
gaaggggaagggggagaggaggaggaggaagagtga
DBGET
integrated database retrieval system
