KEGG   Ovis aries (sheep): 443381
Entry
443381            CDS       T03117                                 
Symbol
ATP1A1
Name
(RefSeq) sodium/potassium-transporting ATPase subunit alpha-1
  KO
K01539  sodium/potassium-transporting ATPase subunit alpha [EC:7.2.2.13]
Organism
oas  Ovis aries (sheep)
Pathway
oas04022  cGMP-PKG signaling pathway
oas04024  cAMP signaling pathway
oas04260  Cardiac muscle contraction
oas04261  Adrenergic signaling in cardiomyocytes
oas04820  Cytoskeleton in muscle cells
oas04911  Insulin secretion
oas04918  Thyroid hormone synthesis
oas04919  Thyroid hormone signaling pathway
oas04925  Aldosterone synthesis and secretion
oas04960  Aldosterone-regulated sodium reabsorption
oas04961  Endocrine and other factor-regulated calcium reabsorption
oas04964  Proximal tubule bicarbonate reclamation
oas04970  Salivary secretion
oas04971  Gastric acid secretion
oas04972  Pancreatic secretion
oas04973  Carbohydrate digestion and absorption
oas04974  Protein digestion and absorption
oas04976  Bile secretion
oas04978  Mineral absorption
Brite
KEGG Orthology (KO) [BR:oas00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04024 cAMP signaling pathway
    443381 (ATP1A1)
   04022 cGMP-PKG signaling pathway
    443381 (ATP1A1)
 09140 Cellular Processes
  09142 Cell motility
   04820 Cytoskeleton in muscle cells
    443381 (ATP1A1)
 09150 Organismal Systems
  09152 Endocrine system
   04911 Insulin secretion
    443381 (ATP1A1)
   04918 Thyroid hormone synthesis
    443381 (ATP1A1)
   04919 Thyroid hormone signaling pathway
    443381 (ATP1A1)
   04925 Aldosterone synthesis and secretion
    443381 (ATP1A1)
  09153 Circulatory system
   04260 Cardiac muscle contraction
    443381 (ATP1A1)
   04261 Adrenergic signaling in cardiomyocytes
    443381 (ATP1A1)
  09154 Digestive system
   04970 Salivary secretion
    443381 (ATP1A1)
   04971 Gastric acid secretion
    443381 (ATP1A1)
   04972 Pancreatic secretion
    443381 (ATP1A1)
   04976 Bile secretion
    443381 (ATP1A1)
   04973 Carbohydrate digestion and absorption
    443381 (ATP1A1)
   04974 Protein digestion and absorption
    443381 (ATP1A1)
   04978 Mineral absorption
    443381 (ATP1A1)
  09155 Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    443381 (ATP1A1)
   04961 Endocrine and other factor-regulated calcium reabsorption
    443381 (ATP1A1)
   04964 Proximal tubule bicarbonate reclamation
    443381 (ATP1A1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:oas04147]
    443381 (ATP1A1)
Enzymes [BR:oas01000]
 7. Translocases
  7.2  Catalysing the translocation of inorganic cations
   7.2.2  Linked to the hydrolysis of a nucleoside triphosphate
    7.2.2.13  Na+/K+-exchanging ATPase
     443381 (ATP1A1)
Exosome [BR:oas04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   443381 (ATP1A1)
  Exosomal proteins of other body fluids (saliva and urine)
   443381 (ATP1A1)
  Exosomal proteins of colorectal cancer cells
   443381 (ATP1A1)
  Exosomal proteins of bladder cancer cells
   443381 (ATP1A1)
SSDB
Motif
Pfam: E1-E2_ATPase Cation_ATPase_C Cation_ATPase Cation_ATPase_N Hydrolase Hydrolase_3 HAD DUF1290
Other DBs
NCBI-GeneID: 443381
NCBI-ProteinID: NP_001009360
UniProt: P04074 A0A836D9U0
LinkDB
Position
1:93717246..93750077
AA seq 1021 aa
MGKGVGRDKYEPAAVSEHGDKKKAKKERDMDELKKEVSMDDHKLSLDELHRKYGTDLNRG
LTTARAAEILARDGPNALTPPPTTPEWVKFCRQLFGGFSMLLWIGAVLCFLAYGIQAATE
EEPQNDNLYLGVVLSAVVIITGCFSYYQEAKSSKIMESFKNMVPQQALVIRNGEKMSINA
EEVVVGDLVEVKGGDRIPADLRIISANGCKVDNSSLTGESEPQTRSPDFTNENPLETRNI
AFFSTNCVEGTARGIVVYTGDRTVMGRIATLASGLEGGQTPIAAEIEHFIHIITGVAVFL
GVSFFILSLILEYTWLEAVIFLIGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLE
AVETLGSTSTICSDKTGTLTQNRMTVAHMWFDNQIHEADTTENQSGVSFDKTSATWLALS
RIAGLCNRAVFQANQDNLPILKRAVAGDASESALLKCIEVCCGSVKEMRERYAKIVEIPF
NSTNKYQLSIHKNANAGEPRHLLVMKGAPERILDRCSSILIHGKEQPLDEELKDAFQNAY
LELGGLGERVLGFCHLMLPDEQFPEGFQFDTDDVNFPVDNLCFVGLISMIDPPRAAVPDA
VGKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGNETVEDIAARLNIPVSQVNPRDARA
CVVHGSDLKDMTPEQLDDILKYHTEIVFARTSPQQKLIIVEGCQRQGAIVAVTGDGVNDS
PALKKADIGVAMGIAGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTS
NIPEITPFLIFIIANIPLPLGTVTILCIDLGTDMVPAISLAYEQAESDIMKRQPRNPQTD
KLVNERLISMAYGQIGMIQALGGFFTYFVIMAENGFLPNHLLGIRVTWDDRWINDVEDSY
GQQWTYEQRKIVEFTCHTAFFVSIVVVQWADLVICKTRRNSVFQQGMKNKILIFGLFEET
ALAAFLSYCPGMGVALRMYPLKPTWWFCAFPYSLLIFVYDEVRKLIIRRRPGGWVEKETY
Y
NT seq 3066 nt   +upstreamnt  +downstreamnt
atggggaagggggttggacgtgataaatatgaaccggctgctgtttcagagcatggcgac
aaaaaaaaggccaagaaagagagggatatggacgagctgaagaaagaagtttctatggat
gatcataaacttagccttgatgaacttcatcgcaaatatggaacagacttgaaccgaggc
ttaacaactgctcgagctgctgagatcctagccagagatggacccaatgccctcacaccc
cctcccacaacccctgaatgggtcaagttctgtcgacagctgtttggggggttctcaatg
ttactgtggattggagcagttctttgcttcctggcctatggcatccaagctgctacagaa
gaggaacctcaaaatgataatctgtaccttggtgtggtgctgtctgccgtcgtcatcata
accgggtgtttctcctactatcaagaagctaaaagctccaagatcatggagtccttcaaa
aacatggttcctcagcaagctctcgtgattcgaaatggtgaaaaaatgagcataaatgcg
gaagaagttgtcgtcggagacctggtggaagtgaaaggaggggatcgaattcctgctgat
ctcaggatcatttccgcgaatggctgcaaggtggataactcctcactcacgggagaatca
gagccacagaccaggtctccggatttcaccaatgaaaatcctctagagacacggaacatt
gcctttttttcaaccaactgtgttgaaggcactgcacgtggcattgttgtgtacaccggg
gatcgaaccgtgatgggcagaattgccaccctggcttctgggctggaagggggccagact
cccatcgctgcggaaattgaacattttatccacatcatcacgggtgtggctgtgttcctg
ggcgtgtctttcttcatcctttctctgatccttgagtacacctggttggaggctgtcatc
ttcctcatcggcatcattgtagccaatgtgccagagggtttgctggccaccgtcacggtg
tgcctgaccctgactgccaagcgcatggccaggaagaactgcttagtgaagaacctggag
gctgtggagaccttgggatccacgtccaccatctgctcagacaaaactggaactctgacc
cagaaccgaatgacagtggcccacatgtggttcgacaaccaaatccatgaggcggacacg
acagagaatcagagcggtgtttcatttgacaagacttcggccacctggctcgctctgtcc
agaattgcaggtctttgtaacagggccgtgtttcaggctaaccaggataacctgcctatc
ctgaagcgggctgtagcaggtgatgcatcagagtctgcgcttctgaagtgcattgaggtg
tgctgcggttctgtgaaggagatgagagagagatatgccaagatcgtcgagatcccgttc
aactccaccaacaagtaccagttatccatccacaagaatgccaatgcaggtgagccccgg
cacctactggtgatgaaaggtgctccggagaggatcctggatcgctgcagctccatcctc
atccatggcaaggagcagcccctggacgaggagctgaaggacgcctttcagaacgcctac
ctggagctgggtggcctgggagaacgtgtgctgggtttctgccacttgatgctgccagat
gagcagtttcctgaaggcttccagtttgacaccgacgatgtgaacttccctgttgataat
ctctgcttcgtggggctcatctccatgattgacccaccacgggctgctgtcccagatgct
gtgggcaaatgccgaagtgctggaatcaaggtcatcatggtcaccggagaccatcccatc
actgccaaagccattgccaaaggcgtgggcatcatctcagaagggaatgagactgtagaa
gacattgctgcccgcctcaacatcccagtgagccaggtgaatcccagggatgccagggcc
tgcgtggtgcatggaagtgatctgaaggacatgactcccgagcaactggatgacattttg
aagtaccacacggagattgtgttcgccaggacctctccgcagcagaagctcatcattgtg
gaaggctgccagagacagggtgccattgtggctgtaactggagacggtgtcaatgactcc
ccggctttgaagaaggcagacattggggttgccatggggattgcaggctcagacgtgtct
aagcaagctgctgacatgatcctcctagatgacaactttgcttcaattgtgactggagta
gaggaaggtcgtctgatctttgataacttgaagaaatccattgcttataccctcaccagt
aacattcctgagattacccccttcctgatatttattattgcaaacattccactccccctg
gggaccgtcaccatcctctgcatagacttgggaacagacatggtccctgctatctccctg
gcttatgagcaagctgagagcgacatcatgaagagacagcccagaaacccccagacagac
aaactcgtgaacgagcggctgatcagcatggcctacggacagattggtatgatccaggcc
ctggggggcttcttcacttactttgtgatcatggctgagaacggcttcctccctaatcac
ctgctgggcatccgagtgacctgggatgaccgttggatcaacgacgtggaggacagctat
gggcagcagtggacctatgaacagaggaagatcgtggaattcacctgccacacggccttc
tttgtcagcatcgtggtggtgcagtgggctgacttggtcatctgcaagaccaggaggaat
tccgtcttccagcaggggatgaagaacaagatcttaatatttggcctcttcgaagagaca
gcccttgctgctttcctttcctactgccctggaatgggtgttgccctgaggatgtatccc
ctcaaacctacctggtggttctgtgccttcccctactcgcttctcatcttcgtgtatgac
gaagtccggaagctcatcatcaggcgacgccctggcggctgggtggagaaggagacctac
tactag

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