Ovis aries (sheep): 443499 Help Entry 443499            CDS       T03117                                  Symbol ITGA4 Name (RefSeq) integrin alpha-4 isoform X1   KO K06483   integrin alpha 4 Organism oas  Ovis aries (sheep) Pathway oas04151   PI3K-Akt signaling pathway oas04510   Focal adhesion oas04512   ECM-receptor interaction oas04514   Cell adhesion molecules oas04640   Hematopoietic cell lineage oas04670   Leukocyte transendothelial migration oas04672   Intestinal immune network for IgA production oas04810   Regulation of actin cytoskeleton oas04820   Cytoskeleton in muscle cells oas05135   Yersinia infection oas05140   Leishmaniasis oas05165   Human papillomavirus infection oas05410   Hypertrophic cardiomyopathy oas05412   Arrhythmogenic right ventricular cardiomyopathy oas05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:oas00001]  09130 Environmental Information Processing   09132 Signal transduction    04151 PI3K-Akt signaling pathway     443499 (ITGA4)   09133 Signaling molecules and interaction    04512 ECM-receptor interaction     443499 (ITGA4)    04514 Cell adhesion molecules     443499 (ITGA4)  09140 Cellular Processes   09144 Cellular community - eukaryotes    04510 Focal adhesion     443499 (ITGA4)   09142 Cell motility    04820 Cytoskeleton in muscle cells     443499 (ITGA4)    04810 Regulation of actin cytoskeleton     443499 (ITGA4)  09150 Organismal Systems   09151 Immune system    04640 Hematopoietic cell lineage     443499 (ITGA4)    04670 Leukocyte transendothelial migration     443499 (ITGA4)    04672 Intestinal immune network for IgA production     443499 (ITGA4)  09160 Human Diseases   09172 Infectious disease: viral    05165 Human papillomavirus infection     443499 (ITGA4)   09171 Infectious disease: bacterial    05135 Yersinia infection     443499 (ITGA4)   09174 Infectious disease: parasitic    05140 Leishmaniasis     443499 (ITGA4)   09166 Cardiovascular disease    05410 Hypertrophic cardiomyopathy     443499 (ITGA4)    05412 Arrhythmogenic right ventricular cardiomyopathy     443499 (ITGA4)    05414 Dilated cardiomyopathy     443499 (ITGA4)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04147 Exosome [BR:oas04147]     443499 (ITGA4)    04515 Cell adhesion molecules [BR:oas04515]     443499 (ITGA4)    04090 CD molecules [BR:oas04090]     443499 (ITGA4) Exosome [BR:oas04147]  Exosomal proteins   Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)    443499 (ITGA4)   Exosomal proteins of other cancer cells    443499 (ITGA4) Cell adhesion molecules [BR:oas04515]  Integrins   Integrin alpha subunits    443499 (ITGA4) CD molecules [BR:oas04090]  Proteins   443499 (ITGA4) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Integrin_A_Ig_1 Integrin_A_Ig_3 Integrin_A_Ig_2 FG-GAP FG-GAP_3 Integrin_alpha DUF11 CATSPERG_C Motif Other DBs NCBI-GeneID:  443499 NCBI-ProteinID:  XP_004004586 UniProt:  W5Q5Y1 LinkDB All DBs Position 2:complement(128281242..128376483) Genome browser AA seq 1034 aa AA seqDB search MAVEARRRPGPRGAAVWEAVMFLLCSGVPTGRPYNVDTESALLYKGPPNTLFGYSVVLHS HGENRWLVVGAPTANWLSNTSVVKPGAIYRCKIGKNPARTCEQLQLGSPFGDPCGKTCLE ERDNQWLGVTLSRQPGENGSIVTCGHRWKNIFYIRTESKLPTGVCYGMPSDLRTELSKRI APCYQDFVKQFGETFASCQAGISSFYTEDLIVMGAPGSFYWTGSLFVYNMTTNKYKAFLD RHNQVKFGSYLGYSVGAGHFRSQHSTEVVGGAPQHEQIGKAYIFSIDAKELNILHEMKGK KLGSYFGASICAVDLNADGFSDLLVGAPMQSTIREEGRVFVYINSGSGAVMNEMETELIG SDKYAARFGESIVSLGDIDNDGFEDVAIGAPQEDDLQGAIYIYNGRVDGISTTFSQRIEG RQISKSLSMFGQSISGQIDADNNGYLDVAVGAFRSDSAVLLRTRPVVIVEASLNHPESVN RTNFDCIENGLPSVCMDLTLCFSYKGKEVPGYIVLLYNISLDVNRKAESPSRFYFSSNGT YDVITRSMQVQSKATSCKTHRAFMRKDVRDILTPIQIEATYHLGHHVVSKRSIEEFPPLQ PILQQKKEKDIIEKTINFARFCAHENCTADLQVSAKIGFLKPHENKTYLAVGSMKTLMLN VSLFNAGDDAYETTLHIKLPTGLYFIKILDLEEKQINCEVTDGSGVVRLDCRVGYIYVDH LSKTDVSFLLDASSLSRAEEDLSITVHAACENEGETGDVTHNEVTVTIPLKYEVMLTVHG FVSPASFMYGPKEEDDEFEMCVTEKMNFTFHVINTGQSMAPNISVEIMIPNSFSPRTDKL FNVLDVQTTAGECHFKNYQRKCTLDQQKGTMETLKDTFRFLSKTDKRLLYCMKADPYCLD ISCHFGKMDSGKEASVHIQLEGRPSILEMDETRALKFEIRATAFPEPNPKVIELKKDENV AHVLLEGLHHQRPRRHFTIMIISSSLLLGLILLFLISYVMWKAGFFKRQYKSILQEENRR DSWSYINSKSDKDE NT seq 3105 nt NT seq  +upstreamnt  +downstreamnt atggctgtggaagcgaggcgaaggccgggcccccgaggggccgccgtctgggaggcggtg atgtttctgttgtgctcgggggtcccgaccgggcgcccctacaacgtggacacggagagt gcgctgctctacaagggaccccccaacaccctgtttggctactcggtggtgctgcacagc cacggggagaaccgatggctcgtagtcggggcgcccactgccaactggctctccaacacg tcagtggtcaaacctggggctatttacagatgcaagattgggaagaatccagccaggacc tgtgaacagctccagctaggtagcccttttggagatccttgtggaaagacttgcttggaa gaaagagataatcaatggctgggggtcacgctttccagacagcctggagaaaacggctcc attgtgacttgtgggcatagatggaaaaatatattttacataaggactgagtctaagctc cccacgggtgtttgctatggaatgccttctgatttacgaacagaactgagtaagagaata gctccatgctatcaagattttgtgaaacagtttggagagacttttgcatcatgtcaagct ggaatatctagtttttacacagaggatttaattgtgatgggagctccaggatcattctat tggactggctctctttttgtgtacaatatgactacaaataaatacaaggctttcttagac agacacaaccaagtaaaatttggaagttatttaggctattcagtcggagctggtcatttt cgcagtcagcacagtactgaggtagttggaggagcccctcaacatgaacagattggtaaa gcttacatattcagcattgatgcaaaagaactaaatatcttacatgaaatgaaaggtaaa aagcttgggtcttattttggagcatctatctgtgccgtggacctcaacgcagatggcttc tcagacctactcgtgggagctcccatgcagagcaccatcagggaagaaggaagagtgttt gtgtacatcaactctggttctggagcagtaatgaacgaaatggagacagagctcattgga agtgacaaatacgctgcacggttcggggaatctatagtcagtcttggcgacattgataat gatggctttgaagatgttgctattggagccccgcaggaagatgacttgcaaggtgcgatt tatatttacaatggccgagtagatgggatctcaacaaccttctcacagagaattgaagga cgtcaaatcagtaaatcattaagtatgtttggacagtctatatctggacaaattgatgca gataacaatggatatctagatgtagcagttggtgcttttcggtctgattctgctgtgttg ctaaggacaagacctgtagtgattgtagaagcttctttgaaccatcctgagtcagtaaat agaacaaattttgactgtattgaaaatggattgccctctgtgtgcatggatctgacactc tgtttctcatataagggcaaagaggttccgggttatattgttttgctttataacataagc ctggatgtgaaccgaaaggcagagtctccatcgagattttacttttcttccaatggaact tatgatgtgattacaagaagcatgcaagtacagagcaaagcaactagctgcaaaacacat cgagcatttatgcggaaagatgtacgggacatcctcaccccaattcagattgaagccact taccacctgggacatcatgtcgtcagtaaacgaagtatagaggaattccctccacttcag ccaattcttcagcagaagaaagaaaaagacatcattgagaaaacaataaactttgccaga ttttgtgcccatgaaaactgtactgctgatttacaggtttctgcaaaaattggatttttg aaaccacatgaaaataaaacctatcttgctgttggaagtatgaagacattgatgttgaac gtgtctttatttaatgctggagatgatgcgtatgagacaactctgcatatcaagctcccc accggtctttacttcattaagattttagatctggaagagaaacaaataaactgtgaagtg acagacggctctggtgtagtgagacttgactgcagggttggttacatatatgtagatcat ctatcaaagacagatgtaagttttcttctggatgccagctcactcagcagagcagaagag gatctcagcatcacagtacatgccgcctgtgaaaatgaaggggaaacaggcgatgtgacg cataatgaggtgactgtgacaatacctcttaagtatgaagtcatgctaacagttcacggg tttgtaagtccagcttcatttatgtatggaccaaaggaggaagatgatgagtttgaaatg tgcgtgacagagaaaatgaacttcactttccacgtcatcaacaccggccaaagcatggct ccaaatattagtgtggaaataatgataccaaattcttttagtccccgaaccgacaagctg ttcaacgttttggatgtccagactactgctggagaatgccattttaagaattatcaaaga aagtgtacattagaccagcaaaaaggcacaatggagacccttaaagatacattcagattt ctgtcaaagactgataagaggctcctgtactgcatgaaagctgatccatattgcttagat atctcatgccattttgggaaaatggacagtggaaaagaagccagtgttcacattcagttg gaaggtcgcccatccattttagaaatggatgagactagagcactgaagtttgaaataaga gcaacagcttttccagagccaaatcccaaagttattgaattaaagaaggatgagaatgtt gcccatgttctcctcgaaggactacatcatcaaagacccagacgccatttcactataatg attatttcaagtagcttgctcctcggacttattttacttttcctcatttcttatgttatg tggaaggctggcttcttcaaaagacagtacaaatctatcctacaagaagaaaatagaaga gacagttggagttacattaacagtaaaagtgataaagatgagtga

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