Ovis aries (sheep): 443544
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Entry
443544 CDS
T03117
Symbol
SHMT1
Name
(RefSeq) serine hydroxymethyltransferase, cytosolic
KO
K00600
glycine hydroxymethyltransferase [EC:
2.1.2.1
]
Organism
oas
Ovis aries (sheep)
Pathway
oas00260
Glycine, serine and threonine metabolism
oas00630
Glyoxylate and dicarboxylate metabolism
oas00670
One carbon pool by folate
oas01100
Metabolic pathways
oas01200
Carbon metabolism
oas01230
Biosynthesis of amino acids
oas01240
Biosynthesis of cofactors
oas01523
Antifolate resistance
oas04981
Folate transport and metabolism
Module
oas_M00141
C1-unit interconversion, eukaryotes
Brite
KEGG Orthology (KO) [BR:
oas00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00630 Glyoxylate and dicarboxylate metabolism
443544 (SHMT1)
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
443544 (SHMT1)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
443544 (SHMT1)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
443544 (SHMT1)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
443544 (SHMT1)
Enzymes [BR:
oas01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.1 glycine hydroxymethyltransferase
443544 (SHMT1)
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Gene cluster
GFIT
Motif
Pfam:
SHMT
DegT_DnrJ_EryC1
Motif
Other DBs
NCBI-GeneID:
443544
NCBI-ProteinID:
NP_001009469
UniProt:
P35623
A0A6P7EF41
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All DBs
Position
11:34072580..34099277
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AA seq
484 aa
AA seq
DB search
MAAPVNKAPRDADLWSLHEKMLAQPLKDNDVEVYNIIKKESNRQRVGLELIASENFASRA
VLEALGSCLNNKYSEGYPGQRYYGGTEFIDELEVLCQKRALQVYGLDPECWGVNVQPYSG
SPANFAVYTALVEPHGRIMGLDLPDGGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGY
INYDQLEENARLFHPRLIIAGTSCYSRNLDYARLRKIADDNGAYLMADMAHISGLVAAGV
VPSPFEHCHVVSTTTHKTLRGCRAGMIFYRKGVRSVDPKTGKETRYNLESLINSAVFPGL
QGGPHNHAIAGVAVALKQAMTPEFRAYQRQVVANCRALAEALMGLGYRVVTGGSDNHLIL
VDLRSKGTDGGRAEKVLEACSIACNKNTCPGDKSALRPSGLRLGTPALTSRGLLEEDFRK
VAHFIHRGIELTLQIQDAVGVKATLKEFMEKLAGAEEHQRAVTALRAEVESFATLFPLPG
LPGF
NT seq
1455 nt
NT seq
+upstream
nt +downstream
nt
atggcagctccagtcaacaaggcacccagagatgccgatttgtggtccttgcatgagaag
atgctggcacagcccctgaaggacaacgatgtcgaggtttacaacatcattaagaaggag
agtaaccggcagagggttggactggagctgatcgcctccgagaactttgccagccgggct
gttctggaggccctaggctcttgcctgaacaacaagtactctgaggggtacccaggccag
aggtactatggtgggacggaattcatcgatgagctagaggtcctctgtcagaagcgagcg
ctgcaggtctatggcctggaccccgagtgctggggggttaacgtccagccttactcaggc
tccccagcaaatttcgcagtgtacacggccctggtggagccccatggccgcatcatgggc
ctggacctgccggatgggggccacctgacccatgggttcatgactgataagaagaagatt
tctgccacgtccatcttttttgaatctatgccttacaaggtgaatcccgataccggctac
atcaactacgaccagctggaggagaacgcccgcctcttccacccgaggctgatcattgca
gggactagctgctactcccggaacctggactacgctcggctgcgcaagatcgctgacgac
aatggggcgtacctcatggctgacatggcacatatcagcgggctggtggcggccggcgtg
gtgccttcccccttcgagcactgccacgtggtgtccaccaccacccacaagaccctgcgg
ggctgccgcgccggcatgatcttctacaggaagggagtgcgcagtgtggaccccaagaca
ggcaaagagactcgctacaacctggagtcgctcatcaactctgctgtgttcccaggcctg
caagggggacctcacaaccacgccattgctggggtcgcggttgctctgaagcaggccatg
actccggagttcagagcctaccagcgccaggttgtggccaactgcagggctctggctgag
gccttgatgggactgggctacagagtggtcacagggggttctgacaaccacttgatcctc
gtggacctccgctccaaaggcacagatggcggcagggcagagaaggtgctggaagcctgc
tccatcgcctgcaacaagaatacctgcccaggtgacaaaagcgcactacggcccagtggg
ctgcgcctggggaccccagcactgacctcccgaggactcttggaagaagatttccgaaag
gttgcccatttcattcacagaggcatagagctgaccctgcagatccaggatgctgtagga
gtgaaggccaccctgaaggagttcatggagaagctggcaggggccgaggagcaccagcgg
gctgtgacagccctcagagcagaggtggagagcttcgccaccctattcccgctgcctggc
ctgcctggcttctag
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