Ovis aries (sheep): 554263 Help Entry 554263            CDS       T03117                                  Symbol TLR4 Name (RefSeq) toll-like receptor 4 precursor   KO K10160   toll-like receptor 4 Organism oas  Ovis aries (sheep) Pathway oas04064   NF-kappa B signaling pathway oas04066   HIF-1 signaling pathway oas04145   Phagosome oas04151   PI3K-Akt signaling pathway oas04217   Necroptosis oas04613   Neutrophil extracellular trap formation oas04620   Toll-like receptor signaling pathway oas04621   NOD-like receptor signaling pathway oas04936   Alcoholic liver disease oas05132   Salmonella infection oas05133   Pertussis oas05134   Legionellosis oas05135   Yersinia infection oas05140   Leishmaniasis oas05142   Chagas disease oas05144   Malaria oas05145   Toxoplasmosis oas05146   Amoebiasis oas05152   Tuberculosis oas05161   Hepatitis B oas05162   Measles oas05164   Influenza A oas05170   Human immunodeficiency virus 1 infection oas05171   Coronavirus disease - COVID-19 oas05205   Proteoglycans in cancer oas05235   PD-L1 expression and PD-1 checkpoint pathway in cancer oas05321   Inflammatory bowel disease oas05323   Rheumatoid arthritis oas05417   Lipid and atherosclerosis Brite KEGG Orthology (KO) [BR:oas00001]  09130 Environmental Information Processing   09132 Signal transduction    04064 NF-kappa B signaling pathway     554263 (TLR4)    04066 HIF-1 signaling pathway     554263 (TLR4)    04151 PI3K-Akt signaling pathway     554263 (TLR4)  09140 Cellular Processes   09141 Transport and catabolism    04145 Phagosome     554263 (TLR4)   09143 Cell growth and death    04217 Necroptosis     554263 (TLR4)  09150 Organismal Systems   09151 Immune system    04613 Neutrophil extracellular trap formation     554263 (TLR4)    04620 Toll-like receptor signaling pathway     554263 (TLR4)    04621 NOD-like receptor signaling pathway     554263 (TLR4)  09160 Human Diseases   09161 Cancer: overview    05205 Proteoglycans in cancer     554263 (TLR4)    05235 PD-L1 expression and PD-1 checkpoint pathway in cancer     554263 (TLR4)   09172 Infectious disease: viral    05170 Human immunodeficiency virus 1 infection     554263 (TLR4)    05161 Hepatitis B     554263 (TLR4)    05171 Coronavirus disease - COVID-19     554263 (TLR4)    05164 Influenza A     554263 (TLR4)    05162 Measles     554263 (TLR4)   09171 Infectious disease: bacterial    05132 Salmonella infection     554263 (TLR4)    05135 Yersinia infection     554263 (TLR4)    05133 Pertussis     554263 (TLR4)    05134 Legionellosis     554263 (TLR4)    05152 Tuberculosis     554263 (TLR4)   09174 Infectious disease: parasitic    05146 Amoebiasis     554263 (TLR4)    05144 Malaria     554263 (TLR4)    05145 Toxoplasmosis     554263 (TLR4)    05140 Leishmaniasis     554263 (TLR4)    05142 Chagas disease     554263 (TLR4)   09163 Immune disease    05323 Rheumatoid arthritis     554263 (TLR4)    05321 Inflammatory bowel disease     554263 (TLR4)   09166 Cardiovascular disease    05417 Lipid and atherosclerosis     554263 (TLR4)   09167 Endocrine and metabolic disease    04936 Alcoholic liver disease     554263 (TLR4)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:oas04131]     554263 (TLR4)   09183 Protein families: signaling and cellular processes    04054 Pattern recognition receptors [BR:oas04054]     554263 (TLR4)    04090 CD molecules [BR:oas04090]     554263 (TLR4)    00536 Glycosaminoglycan binding proteins [BR:oas00536]     554263 (TLR4) Membrane trafficking [BR:oas04131]  Endocytosis   Phagocytosis    Toll-like receptors     554263 (TLR4) Pattern recognition receptors [BR:oas04054]  Membrane-bound pattern recognition receptors   Toll-like receptors    554263 (TLR4) CD molecules [BR:oas04090]  Proteins   554263 (TLR4) Glycosaminoglycan binding proteins [BR:oas00536]  Hyaluronan   Cell surface receptors    554263 (TLR4) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  LRR_8 LRR_4 TIR LRR_1 LRR_14 TIR_2 LRR_5 LRR_9 LRR_Zer-1 LRR_6 LRR_NXF1-5 LRR_EndoS ThsB_TIR LRR_R13L1-DRL21 Motif Other DBs NCBI-GeneID:  554263 NCBI-ProteinID:  NP_001129402 UniProt:  B5DC89 LinkDB All DBs Position 2:complement(5924822..5934668) Genome browser AA seq 840 aa AA seqDB search MARARRAAALIPAMAILSCLRTESWDPCVQVVPNISYQCMELNLYKIPDNIPMSTEMLDL SFNYLRHLGSHNFSRFPELQVLDLSRCEIKIIEDNTFQGLNHLSTLILTGNPIQSLAWGA FSGLSSLQKLVAVETNLVSLDDFPIGHLKTLKELNVAHNFIHSFKLPEYFSNLPNLEHLD LSNNKIQNIYYEDVKVLHQMPLLNLSLDLSLNPLEFIEPGTFKEIKLNGLTLRSNFNSSD VMKTCIQGLAGLKINRLVLGEFKNERKLQKFDRSCLEGLCNLTIEQFRIAYLSKFSWNDT DLFNCLANVSVISLLSISLGSLQALLKDFRWQHLEMINCDFDKFPALKLRSLKKFVFTDN KDVSTFTKTELPSLQYLDLKRNHLSFKSCCSHTDFGTTNLKHLDLSFNDVITLGSNFMGL EQLEHLDFQHSTLKQINAFSTFLSLRNLRYLDISYTNIRIVFHGIFTGLVSLQTLKMAGN SFQNNLLPDIFTELTNLTILDLSKCQLEQVSWAAFHSLPSLQVLNMSHNKLLSLDTFLYE PLHSLRILDCSFNRITASKEQELRNLPRNLTWLNLTQNEFACVCEHQSFLQWVKDQRQLL VGAEQMMCAEPLDVKDMPVLGFRNATCQMSKTIISVSVVTVLLVSVVGVLVYKFYFHLML LAGCKKYGRGESTYDAFVIYSSQDEAWVRNELVKNLEEGVPPFQLCLHYRDFIPGVAIAA NIIQEGFHKSRKVIVVVSQHFIQSRWCIFEYEIAQTWQFLSSRAGIIFIVLQKLEKSLLR QQVELYRLLNRNTYLEWEDSVLGRHVFWRRLRKALLAGKPRSPEGTADAETNPQEATTST NT seq 2523 nt NT seq  +upstreamnt  +downstreamnt atggcgcgtgcccgccgggctgcggctctgatcccggccatggccatcctctcctgcctg agaaccgagagctgggacccttgcgtacaggttgttcctaacatcagttaccaatgcatg gagctgaatctctacaaaatccccgacaacatccccatgtcaaccgagatgctggacctg agctttaactacctgagacatttaggcagccataacttctccaggttcccagaactgcaa gtgctggatttatccagatgcgaaattaagattattgaagacaacacatttcagggtcta aaccacctctccaccttgatactgacgggaaaccctatccagagtttagcctggggagcc ttttctgggctatcaagtttacagaagctggtggccgtggagacaaacctagtatctcta gatgacttccccattggacatctcaaaaccttgaaagagcttaatgtggctcacaatttt atccattccttcaagttacctgaatatttttctaaccttcccaacctggagcacttggat ctttctaacaacaaaatacaaaatatttattatgaagatgtgaaagttctacatcaaatg cccctactcaacctctctttagatttgtccctgaaccctttagaatttattgaaccaggt acctttaaagaaattaagctcaatggattgactctgcgaagtaattttaacagttcagat gtcatgaaaacttgtattcaaggtctggctggtttaaaaatcaaccggctggttttggga gaatttaaaaatgaaaggaagttgcaaaaatttgacagatcttgcctggagggactgtgc aacctgaccattgagcaattccggatagcgtacttgagcaaattctcatggaacgataca gacttatttaattgtttggcaaatgtttctgtgatttctctgttgagtatatctttagga agtctacaagcccttcttaaagattttagatggcaacacttagaaatgattaactgtgac tttgataagtttcctgcactgaagctccgttctctcaaaaagtttgttttcacagacaac aaagatgtaagcacttttactaagactgagctaccaagccttcagtatctagatctcaaa agaaatcacttgagtttcaagagctgctgttctcacactgattttgggacaaccaacctg aagcatttagatctgagcttcaatgacgtcattaccttaggttcaaacttcatgggctta gagcagctagaacacctggattttcagcattccactctgaaacagatcaatgctttttca acgttcctatcactcagaaacctccgctaccttgacatctcttacaccaacatccggatt gtcttccacggcatctttactggcttagtcagtctgcagaccttgaaaatggcaggcaac tcttttcagaacaacttgctccctgacatcttcacagagctgactaacttaaccatcttg gacctctctaagtgtcaactggaacaggtgtcctgggcggcatttcactccctccctagc cttcaggtgctgaatatgagtcacaacaaactcttgtcattggatacatttctttatgaa ccactccactcgctccggatcctagactgcagtttcaaccgtatcacggcctctaaggag caagaactacggaatttgccaaggaacctcacttggctaaatcttactcagaatgaattt gcttgtgtttgtgaacatcagagtttcctgcagtgggtcaaggaccagaggcagctcttg gtgggagctgagcaaatgatgtgtgcagagcctttagatgtgaaggacatgccagtgctt ggtttcaggaatgccacttgtcagatgagcaagacgatcatcagcgtgtcggttgtcact gtactcctggtatctgtggtaggagtcctagtctataagttctatttccacctgatgctt cttgctggctgcaaaaagtatggcagaggtgaaagcacctatgatgcctttgtgatctac tcgagccaggatgaagcctgggtgcggaatgaactggtaaagaacttggaggagggcgtg cccccctttcagctctgccttcactacagggactttattcctggggtggccatcgccgcc aatatcatccaggaaggtttccacaagagccgtaaggtgattgtcgtggtgtcccagcac ttcatccagagccgatggtgtatcttcgagtatgagattgcccagacctggcagtttctg agcagccgtgctggcatcatcttcatcgtcctgcagaagctggagaagtctctcctgcgg cagcaggtggagctctatcgccttctgaacaggaacacctacctggagtgggaggacagt gtcctggggcggcatgtcttctggagaagactcagaaaagccttgctggctggtaagccc cggagtccagaaggaacagcagatgcagagaccaacccgcaagaagcgaccacctccacc tga

DBGET integrated database retrieval system