Ovis aries (sheep): 780447
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Entry
780447 CDS
T03117
Symbol
HSPA5
Name
(RefSeq) endoplasmic reticulum chaperone BiP
KO
K09490
endoplasmic reticulum chaperone BiP [EC:
3.6.4.10
]
Organism
oas
Ovis aries (sheep)
Pathway
oas03060
Protein export
oas04141
Protein processing in endoplasmic reticulum
oas04612
Antigen processing and presentation
oas04918
Thyroid hormone synthesis
oas05012
Parkinson disease
oas05014
Amyotrophic lateral sclerosis
oas05020
Prion disease
oas05022
Pathways of neurodegeneration - multiple diseases
oas05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
oas00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
03060 Protein export
780447 (HSPA5)
04141 Protein processing in endoplasmic reticulum
780447 (HSPA5)
09150 Organismal Systems
09151 Immune system
04612 Antigen processing and presentation
780447 (HSPA5)
09152 Endocrine system
04918 Thyroid hormone synthesis
780447 (HSPA5)
09160 Human Diseases
09164 Neurodegenerative disease
05012 Parkinson disease
780447 (HSPA5)
05014 Amyotrophic lateral sclerosis
780447 (HSPA5)
05020 Prion disease
780447 (HSPA5)
05022 Pathways of neurodegeneration - multiple diseases
780447 (HSPA5)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
780447 (HSPA5)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03110 Chaperones and folding catalysts [BR:
oas03110
]
780447 (HSPA5)
04131 Membrane trafficking [BR:
oas04131
]
780447 (HSPA5)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
oas04147
]
780447 (HSPA5)
Enzymes [BR:
oas01000
]
3. Hydrolases
3.6 Acting on acid anhydrides
3.6.4 Acting on acid anhydrides to facilitate cellular and subcellular movement
3.6.4.10 non-chaperonin molecular chaperone ATPase
780447 (HSPA5)
Chaperones and folding catalysts [BR:
oas03110
]
Heat shock proteins
HSP70 / DNAK
780447 (HSPA5)
Membrane trafficking [BR:
oas04131
]
Endoplasmic reticulum (ER) - Golgi transport
Forward pathways
ER-Golgi intermediate compartment (ERGIC) proteins
780447 (HSPA5)
Autophagy
ER-phagy
ER stress-related proteins
780447 (HSPA5)
Exosome [BR:
oas04147
]
Exosomal proteins
Exosomal proteins of haemopoietic cells (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
780447 (HSPA5)
Exosomal proteins of other body fluids (saliva and urine)
780447 (HSPA5)
Exosomal proteins of colorectal cancer cells
780447 (HSPA5)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
HSP70
MreB_Mbl
Hydantoinase_A
FtsA
DDR
FGGY_C
ParM_N
Motif
Other DBs
NCBI-GeneID:
780447
NCBI-ProteinID:
XP_004005686
UniProt:
A0A6P3EAN0
LinkDB
All DBs
Position
3:10783159..10787445
Genome browser
AA seq
655 aa
AA seq
DB search
MKLSLVAAVLLLLLGTARAEEEDKKEDVGTVVGIDLGTTYSCVGVFKNGRVEIIANDQGN
RITPSYVAFTPEGERLIGDAAKNQLTSNPENTVFDAKRLIGRTWNDPSVQQDIKFLPFKV
VEKKTKPYIQVDVGGGQTKTFAPEEISAMVLTKMKETAEAYLGKKVTHAVVTVPAYFNDA
QRQATKDAGTIAGLNVMRIINEPTAAAIAYGLDKREGEKNILVFDLGGGTFDVSLLTIDN
GVFEVVATNGDTHLGGEDFDQRVMEHFIKLYKKKTGKDVRKDNRAVQKLRREVEKAKRAL
SSQHQARIEIESFYEGEDFSETLTRAKFEELNMDLFRSTMKPVQKVLEDSDLKKSDIDEI
VLVGGSTRIPKIQQLVKEFFNGKEPSRGINPDEAVAYGAAVQAGVLSGDQDTGDLVLLDV
CPLTLGIETVGGVMTKLIPRNTVVPTKKSQIFSTASDNQPTVTIKVYEGERPLTKDNHLL
GTFDLTGIPPAPRGVPQIEVTFEIDVNGILRVTAEDKGTGNKNKITITNDQNRLTPEEIE
RMVNDAEKFAEEDKKLKERIDTRNELESYAYSLKNQIGDKEKLGGKLSSEDKETMEKAVE
EKIEWLESHQDADIEDFKAKKKELEEIVQPIISKLYGSAGPPPTNEEEAADKDEL
NT seq
1968 nt
NT seq
+upstream
nt +downstream
nt
atgaagctgtccctggtggccgcggtgctgctgctgctgctcggcacggcacgggcggag
gaggaggacaagaaggaggacgtgggcacggtggtcggcatcgacctgggtaccacctac
tcctgcgtcggggtgttcaagaacggccgcgtggagatcatcgccaacgatcagggcaac
cgcatcacgccgtcttatgtggctttcactcctgaaggggagcgtctgatcggcgatgca
gccaagaaccagctcacctccaatcctgagaacacagtcttcgacgccaagcgactcatc
ggccggacttggaacgacccgtccgtgcagcaggacatcaagttcttgcctttcaaggtg
gttgaaaagaaaactaaaccatacattcaagttgatgttggaggtgggcaaacaaagaca
tttgctcctgaagaaatttctgccatggttctcactaaaatgaaggaaactgctgaggct
tatttgggaaagaaggttactcatgcagttgttactgtaccagcatatttcaatgatgcc
caacgccaggcaaccaaagatgctggaactattgctggattgaatgtcatgaggatcatc
aatgagccgacagcagctgctatcgcttatggcctggataagagggaaggggagaagaac
atcctggtgttcgacctgggtggtggaacctttgatgtgtctcttctcaccattgataat
ggtgtctttgaagtcgtggccactaacggagacactcatctgggtggagaagactttgac
cagcgtgtcatggaacacttcatcaagctctacaaaaagaagactggcaaagatgttcgg
aaggacaacagagctgtgcagaaactccggcgtgaggtagaaaaggccaaacgggccctg
tcttcccaacatcaagcaagaattgaaattgagtccttctatgaaggagaagacttctcg
gagaccctgactcgggccaaatttgaagagctaaacatggacctgttccgttcaaccatg
aagcctgtccagaaagtgttagaagattctgatttaaagaagtctgatattgatgaaatt
gttcttgttggtggctctactcgaatcccaaagattcaacagctggttaaagagtttttc
aatggcaaggagccatcccgtggcataaacccagatgaggctgtggcatatggtgctgct
gttcaggctggtgtgctctctggtgatcaagatacaggtgacctggtactgcttgatgta
tgtcccctgacacttggtattgaaactgtgggaggtgtcatgaccaaactgattccaagg
aacactgtggtgcccaccaagaagtctcagatcttttctacagcctctgataatcaacca
actgttaccatcaaggtctatgaaggtgaacgacctctgacgaaagacaatcaccttctg
ggaactttcgatctgactggaattcctcctgcaccccgtggggtcccacagattgaagtc
acctttgagatagatgtgaatggcattcttcgagtgacagctgaagacaaaggtacaggc
aacaaaaataagatcacaattaccaatgaccaaaatcgcctgacacctgaagaaattgaa
agaatggtcaatgatgctgagaagtttgctgaagaagacaaaaagctcaaggagcgcatt
gacacaagaaatgaattggaaagctatgcctactctcttaagaatcagattggagataaa
gaaaaactgggaggtaaactttcctcagaagataaggagaccatggaaaaagctgtagaa
gaaaagattgagtggctggaaagtcaccaagatgctgacattgaagatttcaaagctaaa
aagaaggagctagaagaaattgttcagccaattatcagcaaactctatggaagtgcaggc
cctcccccaaccaatgaggaggaagcagcagacaaagatgagttgtag
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