Oreochromis aureus (blue tilapia): 116313987
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Entry
116313987 CDS
T07295
Symbol
lrrk2
Name
(RefSeq) leucine-rich repeat serine/threonine-protein kinase 2
KO
K08844
leucine-rich repeat kinase 2 [EC:
2.7.11.1
]
Organism
oau
Oreochromis aureus (blue tilapia)
Brite
KEGG Orthology (KO) [BR:
oau00001
]
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
oau01001
]
116313987 (lrrk2)
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
oau04131
]
116313987 (lrrk2)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
oau04147
]
116313987 (lrrk2)
Enzymes [BR:
oau01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
116313987 (lrrk2)
Protein kinases [BR:
oau01001
]
Serine/threonine kinases: TKL group
LRRK family
116313987 (lrrk2)
Membrane trafficking [BR:
oau04131
]
Exocytosis
Calcium ion-dependent exocytosis
Kinases and associated proteins
116313987 (lrrk2)
Exosome [BR:
oau04147
]
Exosomal proteins
Exosomal proteins of other body fluids (saliva and urine)
116313987 (lrrk2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
ARM_LRRK2
Beta-prop_LRRK2
ANK_LRRK2
Pkinase
PK_Tyr_Ser-Thr
LRR_4
LRR_8
Roc
COR
Ras
LRR_14
WD40_2
Ank_3
TFCD_C
Beta-prop_EML_2
Ank_2
LRR_13
NACHT
LRR_9
AAA_16
Kdo
AAA_22
Gtr1_RagA
Ank_4
Arf
Viral_helicase1
nSTAND3
SRPRB
AAA_7
DUF7079
Beta-prop_BBS7
PduV-EutP
UNC45-central
Spt5_N
Septin
WD40_Prp19
Motif
Other DBs
NCBI-GeneID:
116313987
NCBI-ProteinID:
XP_031587723
Ensembl:
ENSOABG00000015184
LinkDB
All DBs
Position
LG7:23459105..23489808
Genome browser
AA seq
2533 aa
AA seq
DB search
MVNKEELEERLKKLLVRLKTPQEDRQLCTLIQIIQDLLFLAHTDYAAELFEDKDVHVPLV
LVLSTHISSRGVQQVGWSLLCQLIEICPTTLDQLTRPLDEAQEWEVEGVHQQILKVLSQY
SADCRVTMVALRALALLLRSAKIPLLVLLEEEEDVFGLVVYAMKAFPTSEEVQLQGCTAL
QLLLEEVSDDHLVEFVENQDHAVVLAALKRFPDNSEMQLQALKALLPLAHPGSNVEVLMS
GGTRCYSTIIAAMDAFPEVEELQEKACSLFKRFTSESYNDILVRNGVHRVAVRACQTFPN
NAKLQAAALSCLANLTATIVQNKAVAEQGLEEGEEEENRGNGQVEDMELSWMKECFTALE
LHADEPGVQEAACWAIHSLLLHGAALNHLEEEQDERTPVYRQLMAAMLLHFASPNVFNAA
TSAIATLITNNSKMRSLLLSSGLHVNLVEMMKRHSDSAEVSISACKLLNLLFQGRTASLD
ELTMAMNQILSTMKFHNFNLEVQLEALQASLVFLCPDRSLREHGNSVADPDMADVSLKVL
KNQCVVEGAHILYLEALNRFISSSSIQTCGLKVLSALADCSGAVDLLCQQGAIDTVLHTL
QMFPQEREIHYWGLTLLTYVVSKKKLSRMIVPVLASVVVTALIQYREDSEMLLKCLQVAL
RMLDACSGAAAELQKEDFDRHIFQCLREETDQSISPLRKSVCLALSKMWCDSELHYSMLE
KACIDGDTTMAECLIELGADINKKTKNESLIYQVCERGGPLELVELLLSRGCHEQHLRRA
LAVSVKRGDGPTVIQLLGRLGLDLNNNALCLGGFRLGHLDAAWLSPLLGERSRTYSLRYN
NTKGASLAKYIQFLQRAKSVNCPPRSVTDPCLTSGYISDESDDSSFSFTSLEDGLFFNDD
MESDGSDSLSGALSPKSYNNSSEELRGESLRRKQGRRRHASAESGQTESEHTEPLHRRYG
RNSSSQKVLGSAENSAALPKEKERIHLLDLSGNELNSLSCLNDGFVQQQLWHIHRLDLSY
NCLLEFPSELCLNLKNLTRLDLQGNQLQSLPQELLSLPSLSMLNASRNCVGPQLTFDPDV
TCPTLKQLNLSFNKITTFPFELGHTMHTLEELYMEGNCITELCTPLCLPEIKLLDVSKNG
VENISADFLRSCPKLETLNVSMNKLCSLSRLPSKIMTLKLANNSFASIPEAVLELPVLRS
VDMRTNSIVVLPGPASWVSSIIRELMFSQNCIQTLDLSGPIHKWTRLEKLHLSANRLTEI
PPQIGLLEGLTSLDVSHNTNLRSFPDEMGKLSRLWDLPLDGLQLQLDLKLTGSKTKDIVR
FLQQRLKKAVPYYRMKLIVVGNAGSGKTSLIQQLMKLKRSQLNSKQTSFGIDVRDWTVRE
RDKKKMVLNVWDFSGGEEFSGSHPHFLTSRALYLVVYNISKGTSQVDALKPWLFNIKAVA
PLSPVILVGTHTDVSEDSQLQNCLSKIRQEILIHQGFPVIRDYYMVSVCEDSDAIARLRK
AIVREVTSFKIQDQPVMGQLVPDSYVELERRILQERARVPPEFPVLRHHELLQLIQESQL
QLEEAELPHAIHFLSEVGVLLHFDDPALELQELYFIDPQWLCSVISQKLTLKSCGYWEHP
KGVVQRSVVEKFLSETKCFPKSHLTQFLKLLEKFQIALPFGEDQLLVPSSLSKHRPVIEL
PHCENSEVIVRLYEMPYFPMDYWSRQISRLLEASSYLLCGREKMVRPNRIYWRRGIYLNW
SQEAYCLVEENPSSCVRITVPASCKGRLLLGQVVDHIDSLLEEWFPGLLNTDMHGSGEAL
LKKWALYSPEDGQEWRKIPLEDIFTDFLGASAENRPCTLPVFQTAPDLLLSDQPAGTTLD
SEELDIDLSLENRLGDGGFGTVYRGVYKNEDVAVKIFNKHASELYIYRLLRQELVVLGRL
RHPSLVSLLAAGSTPQVLVMELALRGSLDSLFQKKNVSFNQKLQHRIALQVADGLRYLHS
AMIIYRDLKPHNILLFNLKTDSDIIAKITDYGIAQYCCSMGVRSSEGTAGFRAPEVARGN
VIYNQQADVFSFGLLLYDLMTRGERISDGMKFPSEFDEIAVQGKLPDPVKHYGCSPWPSF
QVLIKECLQESPQDRPTSAQVFDRLNSGEMLCLMRELVVPGVLSAECFILSSGADSNSSS
RRVWLGGGSRTQKKGSITAVDLITNTVATQAGSFEVDTSPVLCLVTVQIPNEDSDWLVAG
TQSGSLVVINSQDTSTWHHLQRVTDAVTSLYFHVHPRRTQRKNYLLVGTADGILSIYEDS
VLKQENGQPVKTLSVGNVNTPVMCLGQSVHSLDSRSVWAGCGPKILSFTADYDVCKSIDT
RPNLFSHQQRSLGSEACVYRMVVDKYVYLSKARTTTVEVWDKRSERMVDCIDCAQIIRRD
RGGDGREAELPSEASPSWATVKALLLPNAAMLWIGTRRGHLLLLELPKHQILQVMEPHCD
SLRCMASALIQTLNRENVVLVLGRRQTQHKNPNDEESVLTVWNSMLPVEVKDLKKHCEKR
EQIAAKMREQLHQ
NT seq
7602 nt
NT seq
+upstream
nt +downstream
nt
atggttaacaaagaggagctggaagaaaggctgaaaaaacttttggtgaggctgaaaact
ccccaggaagacaggcaactgtgcacgctgattcaaatcatccaggatctgcttttcctg
gcgcacaccgactatgcagctgaactgtttgaagacaaagatgtccacgtgcccctcgtg
ctggttctgtctacccacatcagcagcagaggagtccagcaggttggctggtcattgctg
tgtcagctgattgaaatatgccccactacactggaccagttaaccagacctttggatgaa
gcccaagagtgggaggtagagggagtgcaccagcagatcctcaaggtgttatctcagtac
agcgcagattgtcgagtgaccatggttgcactcagagccttggcactgctgctcagatca
gccaagattcctctgctggtgctgctggaggaggaggaggacgtgtttggccttgtggtg
tacgccatgaaggcgtttcctacaagtgaagaagtgcaactccaaggctgcacagctctg
cagctgcttctggaggaagtcagtgatgaccaccttgtggagtttgtggagaaccaggat
cacgctgtggttctggcagcactcaagaggtttccggacaactcagagatgcagctgcag
gctttaaaagcgctgcttcctctggctcaccctggcagtaatgtggaggtgttgatgtca
gggggcactcggtgctacagcaccatcatcgctgccatggatgctttccctgaggtggag
gagctgcaggagaaagcctgctccctgttcaaaaggtttacttcagagagttacaacgac
atcctggtgaggaatggtgtccacagagtcgcagtcagagcctgccagactttccctaac
aacgccaagctgcaagccgctgctctgtcctgcctggctaacctcactgcaaccattgtg
cagaacaaagcggtggccgagcagggtctggaggaaggagaggaggaggagaacaggggt
aacgggcaggtggaggacatggagctgagctggatgaaggaatgctttactgcactggag
ctccacgcagatgagccaggtgttcaggaagctgcgtgctgggccattcacagtctgtta
ctgcacggagctgcactgaaccatctagaagaagagcaggatgaaaggactcctgtttat
agacagctgatggcggccatgctgctccacttcgcctctcctaatgtgtttaatgctgct
accagcgccatcgccacactcatcacaaacaacagtaaaatgcgttctttgctgctgtca
agtggccttcatgtgaatttggtggagatgatgaagagacattcagactcagccgaggtt
tccatcagtgcctgcaaactgttaaacctgctcttccagggaaggacagccagtctggat
gagttgaccatggccatgaaccagatcctcagcaccatgaagtttcataactttaatctt
gaggttcagctggaggctctgcaagccagcttggtcttcctttgcccggacaggagttta
agggagcacggcaactcggtcgcagatcccgacatggccgacgtgtctctgaaggtcctg
aaaaaccagtgtgtggtggaaggagctcacatcctctacctggaggctctcaacaggttc
atcagcagctcatccattcaaacgtgtggtttgaaggtgctgtctgctctggctgactgt
tctggtgcggtggatcttctgtgccagcagggggcgatagacacagtgctgcatacacta
caaatgttcccacaggaacgagagatacactactgggggctgaccctactcacctacgtt
gtgtccaagaagaagctctcgaggatgatcgtacctgtactggcctccgttgtggttacc
gctctcattcagtacagagaagactctgagatgctgctaaagtgtttacaggtggcattg
aggatgctagacgcctgttcaggagcagctgctgaactgcagaaagaagactttgacagg
catatcttccagtgccttagagaagagactgaccagagcatcagtccactgcggaagtca
gtgtgcctggctctgtctaaaatgtggtgcgactcagagctgcactacagcatgctggaa
aaggcctgcatagatggagatacgacaatggccgagtgtctgatcgagctgggagctgac
atcaacaagaagaccaaaaatgagtctctcatttaccaggtctgtgagagaggtggacct
ctggaactggtggaactcttgttaagccgaggctgccacgagcagcacctccgcagggct
ctggccgtgagcgtgaagaggggtgacgggcccacagtcatccagttacttggccgtctg
ggtctggacctcaacaacaatgccctgtgcctgggcggcttcaggctaggccatctggat
gctgcctggctgagccccctgctgggtgaaagaagcagaacttacagtctacgctacaac
aacactaagggcgcgagtctggcaaagtacatccagtttctccagagggccaaaagtgtg
aactgtccccctcggtcagtgactgacccatgtttgacctctggctacatttctgatgag
agcgacgactccagcttcagctttacctctttggaagacggcctgtttttcaacgatgac
atggagagtgatggaagtgattcgctgtctggcgctctttctccaaagtcgtacaacaat
tcatcagaggagctgaggggggaatccttaaggaggaagcagggccgtcgcagacatgcc
agcgcagagagtggtcagactgagagcgagcacacggagcctcttcacagaagatacgga
cggaatagctcgagtcaaaaagtgctggggtctgccgagaactctgctgctctgcccaaa
gagaaagagaggatccacctgctggacctatctgggaatgagctgaactccctgtcctgt
ctcaacgatggctttgtccagcagcagctgtggcatatccaccgtctggacctgagctat
aattgtctgctcgagtttccctctgagctctgcctgaatttgaagaatttgactcgacta
gacctgcaggggaatcagctccagtcgctgccacaggagctgctgtctctgccctcgctg
agcatgctgaacgcctctcgtaactgcgttggcccgcagctgacctttgaccctgatgtt
acctgtccaacactgaagcagctcaacctttcgttcaacaaaatcaccacattccctttc
gagctgggccacaccatgcatacgctggaggagctttatatggaaggaaactgtatcact
gagctgtgcacacctctttgtctgcctgagattaagttgcttgatgtgagcaagaacggt
gtggagaatatttctgcagatttcctgagaagctgccccaaactggaaactttgaatgtc
tctatgaacaaactctgttccctgtcccggctgccatctaagattatgacactaaaactt
gcaaacaatagctttgcatcaattcccgaggctgtacttgaacttccagtgttacggtca
gtagatatgagaaccaacagcatcgttgttctgcctggcccggcgtcctgggtgtccagc
atcatcagagagctgatgttcagtcagaactgcatacagactctggatctgagtggacct
atccacaaatggaccagactggagaaactccaccttagtgccaataggctcactgagatc
cctccccagattggcttgttggaaggcctgacttccctggatgtgagtcataacactaac
ctgcgctcattcccagatgaaatgggaaaactgagcagactgtgggacctgccactagat
ggccttcagctgcagctggacctcaaactcactggcagcaagacaaaagacatagtcagg
ttccttcagcagcggctgaagaaggcagtgccatactatcggatgaagctcatcgtggtg
gggaacgcaggcagtggaaagaccagcctgatccagcagctgatgaagctaaaacgctcg
cagctgaactcaaaacagacgtcttttggcattgacgtccgcgactggaccgtcagggaa
cgagacaagaagaaaatggtgctgaatgtctgggacttttcaggaggagaggagttcagt
ggttctcaccctcacttcctgacgtccagagctctctacctggtagtttacaacatcagc
aagggaactagtcaagtggacgctctcaaaccttggctcttcaacatcaaagcagtagca
ccgctgtctccagtcattctggtgggcacccacacagatgtgagtgaggactcacagctg
cagaactgcctgagcaaaatcagacaggagatcctgatccaccaaggcttccctgttatc
agggattattacatggtctcagtctgtgaggactcggatgccatcgccagactccgtaag
gccattgtccgggaggtcaccagcttcaagatacaagaccagcccgtgatgggtcagctg
gtgccagacagctacgtggagctggagcgccggattcttcaggaaagagccagggttcct
ccagagttccctgtcctcaggcaccatgagctcctgcagctcatccaagagagtcagctg
cagctggaggaagctgagctccctcatgccatccacttcctcagcgaagtcggggttcta
ttgcacttcgatgatcctgcacttgagcttcaggagctttactttattgacccacagtgg
ctatgcagtgtcatctcacagaaactgaccttaaagagctgtggctactgggagcatcct
aaaggagtggtccagcgctctgtcgtggaaaagtttctgtctgagacgaagtgtttccca
aagagtcacctgacacagttcttgaagctgctggagaagtttcagattgctcttccgttt
ggcgaggaccagctgctggtacccagcagtttgtccaaacacagacccgtaatagaactg
cctcactgtgagaactctgaggtgatcgtccgactgtatgagatgccgtacttccccatg
gattactggtctcggcagatcagccgcctgctagaggcatcctcctacttgctttgtgga
agggaaaaaatggtccgacccaaccggatctactggaggagaggaatttacctaaactgg
tcccaggaggcgtactgtctggtggaggaaaacccctccagctgtgtcagaataaccgtg
cctgcatcatgcaaaggccggctgctgctgggtcaggtggtggatcacattgactccctg
ctggaggaatggtttcccggcctgctaaacaccgacatgcacggcagtggagaagctctg
ctgaagaagtgggctctgtacagcccagaggatgggcaggagtggaggaagattcccctg
gaagacatttttacagattttttgggagcgagtgcagaaaatcggccctgcactcttccc
gtctttcaaacagcccctgatctgttattgagtgaccagcctgcaggaacaacactggac
agtgaagaactggatatagatctgtctttagagaaccgactgggggacggtggctttgga
actgtctatcgaggcgtctataagaacgaagatgtagctgtgaagatattcaacaagcat
gcttctgagctttacatctacagactcctcagacaggaattagtcgttttgggtcgcctc
cgtcaccccagcctggtgagcctgctggcagccggctcgactcctcaggtcctggtgatg
gagctggctctgcgcggctctctggattcccttttccaaaagaagaatgttagcttcaac
caaaagctccagcacaggattgccctgcaggtggcagatgggctcaggtaccttcactca
gccatgatcatctatcgggatctgaagcctcacaacatcctcctgttcaacctgaagacc
gactctgacatcatcgccaagatcacagactacggcatcgctcagtactgctgcagcatg
ggagtaagaagctccgaggggacagcaggtttccgagctccagaggttgcccgaggtaat
gtgatttataatcagcaggctgatgtgttctcgttcggcctgctgctctacgacctgatg
acgcgtggcgagcgcatttcagacggcatgaagtttcccagcgagtttgatgaaattgca
gttcagggaaagctgccagatccagttaaacactatggttgctccccttggcccagcttt
caggttctaataaaggagtgtctgcaggagagcccacaggatcgacccacttctgctcag
gtgtttgacaggttgaattcaggtgaaatgctgtgtcttatgagggagcttgtggttccc
ggggttttgagcgccgagtgcttcattctgagctctggcgccgacagcaattcttccagc
cgccgggtctggcttggtggaggcagcaggacccagaagaagggatccatcacagctgtg
gacctgatcaccaacacggtcgctacacaggctggttctttcgaggtcgacaccagtccc
gtcctgtgcctcgtgactgtccaaatcccaaacgaggacagcgattggctggtggcaggc
acccagtctggctctttagtggtcatcaacagtcaggacacgtcgacttggcaccacctg
cagagggtcaccgacgccgtcacatcactgtacttccatgtacaccctcgacgcactcaa
agaaagaattatttgctggttgggacagcagatggaattcttagcatttatgaggactcc
gtgctcaagcaggagaatggccaaccggttaaaacgctcagtgtgggcaacgtcaacact
ccggtcatgtgtttgggccagtcggtgcattcactggacagcaggtctgtgtgggccggc
tgcggacccaagatcctttccttcactgctgactatgatgtctgcaagtccatcgacaca
agaccgaacctcttttcccaccagcagcggtcactggggagcgaggcgtgtgtgtatcgt
atggttgtggataaatacgtgtacctcagcaaagccaggacaacaactgttgaggtttgg
gacaagaggagcgagaggatggtggactgtattgactgtgctcagattattagacgtgac
agaggcggggacggcagagaagctgagctgccctctgaggcgtcgccctcctgggccaca
gtgaaggccctgctcttgccaaacgccgccatgctctggatcggcactagaaggggccac
ctgctgctactggagctccccaaacaccaaattctgcaggtcatggagccccactgtgat
tctctccgctgcatggcatctgcactcatacaaacacttaacagggagaatgtggtgctg
gttttgggccgaagacaaactcagcacaagaatccaaatgatgaggagtctgtgcttacg
gtgtggaacagcatgctcccggtggaggtcaaagacctgaaaaagcactgcgagaagaga
gagcagatcgcagccaaaatgagagagcagctccaccagtga
DBGET
integrated database retrieval system
