Oreochromis aureus (blue tilapia): 116335057 Help Entry 116335057         CDS       T07295                                  Symbol hmcn1 Name (RefSeq) hemicentin-1 isoform X1   KO K17341   hemicentin Organism oau  Oreochromis aureus (blue tilapia) Brite KEGG Orthology (KO) [BR:oau00001]  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04990 Domain-containing proteins not elsewhere classified [BR:oau04990]     116335057 (hmcn1) Domain-containing proteins not elsewhere classified [BR:oau04990]  EGF-like domain-containing proteins   hEGF / cEGF domain-containing proteins    116335057 (hmcn1) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  I-set Ig_3 Ig_2 ig V-set C2-set_2 TSP_1 EGF_CA VWA_4 G2F C2-set_3 cEGF V-set_CD47 TSP1_spondin Ig_6 Receptor_2B4 GBD_Hemicentin FXa_inhibition TSP1_CFP_C EGF_3 EGF TSP1_ADAMTS TSP1_CCN VWA7_4 Fibulin_C hEGF Motif Other DBs NCBI-GeneID:  116335057 NCBI-ProteinID:  XP_031614518 LinkDB All DBs Position LG17:complement(2482047..2570105) Genome browser AA seq 5637 aa AA seqDB search MAKTKYRETMTEKTPGSLMWLPLVLSVVLAAGQDANTGATKEDIPEGASTLAFVFDVTGS MYDDLVQVIEGASKILETSLSRPKRPLYNFALVPFHDPEIGPVTITTDPKKFQYELRELY VQGGGDCPEMSIGAIKIALEISLPGSYIYVFTDARSKDYKLTHEVLQLIQQKQSQVVFVL TGDCDDRTHIGYKVYEEIASTSSGQVFHLDKRQVNEVLKWVEEAVQSSKVHLLSTDHFTG ISNTWQMPFDPSLKEVTVALSGPAPDIEIKNPQGKLVGKSDGLTELLHIPNSAKVVNIKD PQPGMWSIKTASEGRHSVRISGLSTIDFRAGFSRKATMDFKKTSSRPVQGIPTHILLNTT GLSPPARPDRLELLSISGTVIKTLPIRYYPDRQPYNLWNITEFIPPNEAFFLRVTGYDRD GFLFQRVSSVSFSNIVPDAPKVLMPAKTHGYYLQRGTIKCQVESFIPFTLRFSRDGGRLG VDQLFSESDSASWEIAEVTLKDEGYFECIAISSAGTGRALTFLDVSEPPPAVTVQGNVTA SPGSRAVLTCHAVSTVSFNLTWLRGGQDARLDPRVNILANLSLQVSAVTPDHSGWYECHA VNEGGVTAERIYLTVQEVPSVSVEPHNQTYMAGNDVQISCSASGYPPPRLVWTHNGMFIT ASSRHRMTPGGSLVIKNTEKKDGGAYGCLASNQAGTDSVTSILTYIESPVVSVAFSEILI GVGEATVMACSASGIPQPEIWWYKGHAKLRPSSLLEVDTSGGTLTIKKTQNADAGDYTCL AVNAAGTASGRISLSVGAAPKFTVEPSDVAVDIGFNVTLRCYVQGYPKPEIAWRREDGSP LFNRPRTHGTISQSKGHLQITNLWVGDEGVYICEAQNQFGKIQTQASIAVTGLVSPVIAM SPAVLSVIEDQPMTLPCVLLAGNPLPERQWLHNYGLVTSDQYVSVRRDGSLHIERVRLDD AGDYTCLAENAVGAANHTTAVNVYVIPTIQHGPQVFSTIEGTPISLPCRAAGVPAPDITW TKGGELVNLGGSAFSLNPDGSLLITSPSGNETGEFICTAANAAGHASRKVQLTVYVRPRS KVGDDGHSAGPTKMSVIEGEDAVLPCDVHSVPPPIISWAKERQLISPHSPRHAKLPSGSM KILETRLSDSGLYVCVASNIAGNLTQSIELSILVPPSIHAGPRVMKVQVGHPVELPCVVK GFPKPVLIWTKDGKRYPVSPDGSLALTNVGLDDEGTYTCTATNTAGRDEARVQLVVQVPP VVEVLEPPFNSPLQERVANQRIAFPCPAKGLPKPVIRWLRNGQELTGNEPGVSILEDGTL LILASVSPLDNGEYVCTAANDAGSTERKYQLKVNVPPDFRDRETSGNLSVVLSQPTSLVC DVTGTPTPVITWYKDGAPVVASSNVQIVDMGKTLRLLEAETADAGSYSCKAINVAGNTEK SFFLDVLVPPTIIGSGSPQDVSAIIRQAVSLECKVQGIPFPAIQWYKDRKPVFLGDPNLE VTNRGQVLRIKSARLGDQARYQCSATNTAGKQSKDFNLSVYVPPSIKGGNVSTEVTALLD TAVTLECEARGVPLPSITWHRKGQIILSSRQAQYAERGRYLKILRAQASDAGQYTCKVTS VAGSAEKSYMLDVYLPPTVTGGDKGPIKRKVVLSKSLILECEAGGHPPPSLTWLKDGVPV RDGASVRVLEQGKKLEIPSAAVSDSGHYICVATSIAGEKEVKYDVRVLVPPFIDGADNVT VTTVILNTPLELECHTAGTPAPVITWHKDGKLLRQGEGLWIAAGGRRLVISRAQVSDTAL FQCVATSEAGNHNKDFSVIVQVPPSIRTNGPTERSVILHKPMSLDCISSGIPPPTITWLK NGRPVDATSEHLQLESAGRTLKITEARLEDSGKFTCLATNAAGEAQQHIRLSVHEPPSIP SSGETINQTILSGFSTELECKAAGSPLPAITWYKDGRPLTSAAGVTLRKRGQMLEIERAQ LSDAGIYRCVAVNLAGAAEISHRLQVLVPPVISSRGGTVTVVVNEAVRLECEATGVPAPS ITWLKDGSPVASLSHGIQVFAGGRVLSLDSAQVSDTGRYTCVAVNAGGEQHRDYDLKVYV PPNIQGEEVNATVMLGQPVELHCQSDAVPPPTLSWLKDGRPLFRKPGLTVSADVSLLKIS RVHVQDSGRYTCEATNVAGKTEKNYNLNVWVSPSIRGSEEVSPLTVVEGSLITLVCESSG IPPPSLTWTKDGSEVKSDQRVRILSGGRQLQISSAEKTDAASYTCTASSAAGTISKEYSL QVYVRPSIRRTEGDADEVIVIKGGDVTLQCDAEGVPRPAVTWLKDGRPITGHHGAKVLNE GRLLQIKDAKVSDTGRYTCIAVNVAGQADSKHDISVHVPPSITGQVQFPENVSVVMRNPV GLICEASGIPLPTISWLKDGQPIKTTSSARILSGGRSLRLMHAAAADAGRYTCIVSNSAG EERKTFDLDILVPPSIVEEGTVVDTKVKEKHNITLTCEASGNPVPEIKWLKDGQLLVPDG HYQVLSHGRFLQISGAQVADTGRYSCLASNSAGDRSRHYNLNVLVSPTIAGSGPDISAEE VTVTLSSPTSLVCEVQSYPPALIMWLKDGTPFESSRNVRVLPGGQTLQILNAKQEDAGRY TCVATNEAGETLKHYEVKVYVPPQINKNDIPGEGLAPKEVKIKVNSSLTLECVAQAFPTP ALQWYKDGQILQSDDHVSITANGRIVQIKHAQVSDTGRYTCVATNIAGEDEKDFDVNIQV PPNFNRPGADGDTTSSSGFGVDARDVILNNPISLYCETNAVPPPTLTWYKDGHLLTSNDK VLILPGGRVLQIPRAQIEDSGRYTCVAVNEAGEDSIQYDVRVLLPPTIRGTDSDLPDEVT VLVNKTAQLECHVDGNPAPKISWFKDNQPITSNSLHRILSNGRALQILTAQVSDTGRYVC AAENVAGSAEKIFNLNVHVPPTIIGLSSENVTVVANNFVALSCEATGFPPPTLGWLNDRG PIQANTNALIMPGGRTLQILKAKVSDGGKYSCVALNAAGEAHKHIYLTVFVPPSIRDNSG DSPVVVNVLVGKSVTLECESNAVPPPVITWYKNGRVVTESANLRVLAEGQILQIEGSEVS DTGQYVCMATNVAGQVDKHFHLNIYVPPSIDGPAEETVVETISNPVIFNCDASGIPPPTL TWLKNGRTIENSESLEMHIFSGGSKLQIARSQLADSGTYTCVASNVEGKAYKRYRLTIQV PPSISGSELPSEMGVLLNQTIQLVCQAQGAPTPTIQWLKDGEAINSTGSKALRISGNGSK LTVLRAQTADSGKYTCVATNAAGEEDRIFNLNVYVPPVIVGNSGAVEELAAVLDSSVSIE CVATGSPLPQLNWLRNGLPLPVSSHIRLLSAGQVLRMARIQVSDGGRYTCVASNRAGVDN KHYNLQVHVPPGLDGAGSTEDVTVVGGNLASLLCIADGTPTPTVSWLKDGATLVPDRHVV LLNSNTNLRIRQAQVGDTGRYTCVANNTAGEARRHFNLKVMDPPRIEGSGVPAEVSVVVN NVLELHCEAAGIPTPSLTWLKDGRPLPQTDSLRLLQGGKVLHVASAQLEDTGRYTCLANN PAGDDDKDFLVRVHVPPNIVGDSTPRDMSVLQNRQVTLECKSDAVPPPTLTWLKDGQPLQ ASARVRVLSGGRYLQINMAELSDRAQYTCVASNIAGQTTRKFNLTVNVAPAIKDGPQSVT VHVNKPAMLECVVSGVPPPQVTWRKHGAILAGNNPRYTFAEDGSLRINSAQVTDTGRYLC MATNQAGTQRKRVDLQVYVPPSIADGRTNVTVIVNVQTTLSCEATGIPKPTASWRKNGRL INTDQNQNIYRLLSSGSLVVIAPTVEDTAVYQCVASNEAGEDTRSINLTVNVPPSIADEL TELVVTRLSPVVIPCTASGIPEPTIHWSKDGMKLPEEGLGYSILATGPIEITSAELTHAG RYSCTAQNAAGSTHRHVQLTVQELPVIQSHPSALDVILNNPVSLPCRATGSPSPTITWQK EGINVPSTGGRSTILPNGSLQISKATLSDSGMYICVAQNPAGTALGKTRLRVQVPPVISS DTREYLAPVDSSVMLQCQADGSPPPSVTWHKDGRVLSETVRLRVLSSGSLQIAFIQPSDA GRYTCTAANAAGTVSLEMSLTVQIPPLIRGGEQEVVVVENSQVQLVCLAEGVPQPKLSWE KEGSPVSESVGEYTILPSGELVIDSAQPEDAGSYTCVATNSVGQDSWTVTLLVHTHPIFT ELLGDVALNKGERLMLFCGVSGIPLPSITWAFNNNIIPVHYDQTNGHSELVIERVSKDDA GTYTCVAENDVGTIKSLAFVYVKEPPVIDGDLHSNRIEPLGGNAILNCEVRGDPLPTIQW SKNGINIQISNRIRQLDNGSLAIYGTVSEDAGNYMCVATNDAGVVERSVTLTLHSAPAII VEPVETVVDAGTTAVLNCQAEGEPTPMIEWSRQGRPLLGNNRFSALSNGSLRIISAQKED TAEYECVARNLLGSVLVKVTLTVRVHGGFSEWAEWGPCTVSCGVGNQKRLRQCNKPLPAN GGRHCAGSDTETRSCQGKPCPVDGNWSEWSLWEECSRSCGEGNRTRVRTCSSPPPQHGGR PCEGKAVDVVMCRVRPCPVGGNWGSWLPWSPCSETCGRGVQSRIRLCNNPPPAFDGSQCV GTDTQTQMCKEKPCPVDGKWSSWVSWGACSISCGGGTRQRTRLCASPAPQHGGRQCEGND VQIDFCNSDPCPISGNWGPWSSWGSCSKTCNGGQMRRYRTCDNPRPAYGGRACAGADTQI QRCSTVKCPVDGTWGSWQPWEECSASCGGGQRTRVRLCDSPSPSDGGRPCPGDSTQLSRC NTQACPGGPLKARGSIIGNINDIEFGVSILNASITNSEYGSRIIKATISNVPRTLGPAMR KLISILNPVYWTTAHEVGEAVNGYTLTGGIFRRETQVEFATGEILRMTHIVRGLDSDGAL LLDIVVNGHILQLPSHALISIKDYTEDYIQTGPGQLYALSTRMFSIDKESVPYTWNHTVS YDPSKGKMPYLVETLRAAAISAHYHPLEEVLEYSIQASISKGDRSNQCPRGFTLVAAGPY CADENECEVGNPCSHACHNTMGTYYCSCPRGLTISADGRTCQDIDECSLGDNVCHDAEDC ENTIGSYRCVMRCGRGFRRTADGYSCTDVNECQESNPCNQRCLNTIGSYRCACEPGFLLR SRRCIDINECRQRVCRSDQQCKNTRGGYICIDLCPSGMTKGGNGTCVDVDECSDGTHQCR YNQICENTRGSYHCTCPRGYRSQGVGRPCVDVNECERRPQPCAHQCINTPGSFKCACPPG RHLLGDGKSCAGLERLPSYESYSYSFRTSQSAPGGGSSQMLYHNLASQSYHSYAAPVRGR YRSRSRREMRVHSSHQGVLACQQGFEPRGHRCLDINECEVRDTCQHECTNTPGSYRCLCP AGYRLMTNGKTCQDTDECLEQNIQCGVNRMCFNMRGSYQCIDTPCPPNYQRDPVTGFCLR NCQPNDLECALSPYALEYKLLSLPFGIAANQDLIRLVAYTQDGVMHPRTSFLVVDEDFAL PFALRDENLKGVLFTTRPLREPRTYRMKVRALSYSEDGGIEYQTTFIVYIAVSAYPY NT seq 16914 nt NT seq  +upstreamnt  +downstreamnt atggcgaaaacaaaatatcgtgaaacaatgacagaaaagactcctggatcactgatgtgg cttccgctcgtcctctcagtggtgctggccgcagggcaagacgcaaacacgggggccaca aaggaggacatcccggagggcgcatccaccctggcgttcgtctttgatgtgaccggctcc atgtacgacgacttggtccaagtgatagagggcgcatccaagattttggagacatccctg agcagaccgaagagacctttgtataactttgccctggtgccctttcacgacccagagatt ggacccgttacaatcacaacagacccaaagaagttccagtatgagctgagagagctgtac gttcagggaggaggagactgtccggagatgagcattggtgccattaagattgccttggag atctccttgcccggatcgtatatctatgtcttcactgacgcgcgctctaaagattataag ctcacccatgaggtcctgcagctcattcagcagaaacagtcacaggtggtgtttgtgctg accggagactgtgacgacaggactcacattggttacaaggtatacgaggagattgcctct acaagctctgggcaggtcttccatctagataagagacaggtcaatgaggttcttaaatgg gtggaggaggcagtgcagtcctcaaaggtccacctgttgtccactgatcatttcactgga atcagcaacacgtggcagatgccctttgaccccagtctcaaggaagtcactgtggcactc agtggcccggcacctgacattgagatcaagaacccccaggggaagcttgtggggaagagt gatggcctcactgagcttttgcacattcccaactctgccaaagttgtcaacatcaaggat ccacagcctgggatgtggtctatcaagaccgcaagtgaaggaaggcactcagtccgtatc tcaggtctcagtaccattgacttccgagctgggttttccaggaaagccaccatggacttt aaaaagacgtccagtaggccggttcaaggtattcccacccatatccttctgaacaccact ggactctctcctcctgctcgacctgacaggctggagctcctgtctatctctggcacagtg atcaaaactttgccaatccggtactacccggaccgccaaccatacaacctctggaacatc acagagttcataccacccaacgaggccttcttcctgcgagtgacaggatatgaccgcgac ggtttcctgttccagagagtctcgagtgtttccttctccaatattgtacctgatgctcct aaggtcctgatgccagccaaaactcatggttactacctccagagagggacaatcaaatgc caggtagagagtttcatccctttcacactgcgcttcagcagggatggaggacgacttggg gtagaccaacttttcagtgagtctgacagtgcatcatgggaaatagccgaggtaactcta aaggacgagggttacttcgagtgcattgccatcagcagtgctggaacaggacgagctctg acctttctggatgtatcagagccccctccagccgtcacagtccagggtaacgtaactgcc tccccgggctcccgggctgtcctcacttgccacgccgttagcaccgtcagcttcaacctc acctggctgagaggaggccaagatgcccgtctggacccacgcgtgaacatcctcgccaac ctttcactgcaggtgtccgccgtaaccccagatcattctggctggtacgaatgtcacgct gtaaatgagggaggggtgactgcagagcggatctacctcactgtacaagaggtgcccagc gtgtcagtagagccgcacaatcagacctatatggcaggaaacgatgtgcagatcagctgc tcggctagcggctatcctccacctcgcctggtgtggacccacaacggcatgttcattacg gcgtccagcagacacaggatgactcccggtggctctctggttataaaaaatacagagaaa aaggatggaggagcgtatggctgcctggccagcaaccaggctgggaccgactcagtgacc tccatcctcacttacattgagtctcctgttgtgtctgtggcattcagcgagattcttatt ggtgttggagaagccactgtgatggcctgttcagcatctggaatcccccagcctgagatc tggtggtacaaaggccacgcaaagctccgcccatcgtccctcttggaggtggacacatcg ggggggacgctgaccatcaagaagacccagaatgccgatgctggagattacacctgcttg gctgtcaacgctgctggcacggcatcaggacggatctctctgagcgttggagctgcacct aagttcactgtagagccgtcggatgtggctgtggacatcggcttcaacgtgaccctgcgc tgctatgtccaaggttaccctaaaccagagatcgcctggcggagagaggacggctcgcca cttttcaacaggcctcgcacacatggcacgatctcacagagcaaagggcatctacagatc accaacctatgggtgggggatgagggggtttatatttgtgaggcccagaatcagtttggc aagatccaaacccaggccagcatcgctgtgactggattagtttcacccgtcatcgcgatg agtccggctgtgctgagcgtgatcgaggaccagccgatgactcttccttgcgtgctgctt gctgggaatccgctgcccgagaggcagtggctgcacaactacggcctggtgacctcagac cagtatgtgtcagtgaggagggatggcagtctgcatattgagagagttcggctggatgat gcgggtgactacacctgcctggctgagaacgctgttggggccgccaaccacacaaccgct gtcaacgtttacgtgattcccaccattcagcatggccctcaggtattcagcacaatcgaa ggaacgcccatctctctgccctgccgcgccgctggagtaccagctcctgatatcacctgg acaaagggtggggagctagtgaacttgggtggttcggccttctcgttgaatcccgacggc agcctccttattacttccccttctggaaatgagactggagagttcatctgtactgctgct aatgctgctggccatgcttccaggaaggtccagctcacggtctatgtccgaccgaggtcc aaagttggcgatgacggacactcagcaggtccgacgaagatgtcggtgatcgagggtgag gatgccgttttgccatgcgacgtccacagtgtcccgcctcccatcatcagttgggccaaa gagaggcaactaatctctccgcactctcccagacatgcaaagcttccctctggatctatg aagatcttagagaccaggctgtcagacagtggactttatgtgtgtgttgcttccaatatt gctggaaacttaacgcaatccattgagctgagcattttggtgcccccgagtattcatgct ggccccagggtaatgaaggtgcaggtgggtcaccctgtggagctgccatgtgtggtgaag ggattcccaaagcccgtgctaatctggaccaaggatggtaaaagatacccggtgtcacct gatggcagtctggccttgaccaatgtgggactggatgatgaaggaacctacacttgcaca gcgaccaacactgcaggcagagatgaggctcgagttcagcttgtagttcaagtgcccccc gttgttgaagtactggagccccccttcaacagtcctctgcaggagagggttgccaatcag cgtatcgccttcccctgccctgccaaaggtcttcccaagccagtgattcgctggttgcgt aatggccaggagctgacaggtaatgagcctggcgtgtccatcctagaggatggtacactg ctgattctggcctctgtttcaccgctggataatggagagtacgtctgtaccgctgccaac gacgctggatccactgagaggaagtaccagctcaaagtcaacgtacccccagatttccgt gacagagaaacatccggcaacctgtcagtggtcctgagccagcccaccagcttggtgtgt gacgtcacaggaactccaacacctgtcatcacctggtacaaggatggagcccctgtagtt gcaagtagcaacgtccagattgttgatatgggaaaaactctgagactgctggaggcagaa acggcagatgcaggcagctacagctgtaaagccatcaacgtcgcaggaaacactgaaaaa agctttttcttggatgtgcttgtcccaccaacaattataggttcgggctctcctcaagat gtttcagcaattatcagacaagctgtctctcttgagtgtaaggtgcagggaatccccttt cctgcaatccagtggtacaaggacaggaagccggtgtttcttggcgatcccaatctggag gtcacaaacaggggtcaggttctgagaataaaaagtgcccgtcttggagaccaggcccgc taccagtgtagtgccacgaatacagctgggaaacagtccaaggactttaaccttagtgtc tatgtgcccccctccatcaaaggaggtaacgtcagcacagaggtgacagcactgctggat actgcggtaactctggagtgtgaggcacgtggggtgccgcttccttccataacctggcac cgaaaaggacaaatcatcctgtccagccgtcaggctcaatatgcagagcgaggccgctac ttgaagatccttcgtgcacaggcctctgatgctggacagtacacgtgtaaggtgaccagc gtggctgggagcgctgagaaaagctacatgctggacgtctacttgcctcccacagtcaca ggcggggataaagggcccatcaaaaggaaggtggttctcagtaaatctctgatcctggag tgtgaggctggaggacaccctccaccctctcttacatggctgaaggatggagtccctgtg cgcgatggggcaagtgtccgtgtgctcgagcagggaaagaaactagaaatcccctcggcc gccgtctcagactcgggacactacatctgcgtggctacgagcatcgccggggagaaagag gtcaaatatgacgtcagagttttagttcctcctttcatcgatggagctgataatgtgacg gtcaccacagttatacttaacacccctttggagctcgagtgtcacaccgcgggaacacct gcacctgtaataacatggcataaggatggaaaactattgcgacaaggtgaaggattgtgg attgcagccggtgggcgacgcctagtcatttctcgcgctcaggtctctgacacagctctc tttcagtgtgtggccaccagtgaggcaggaaaccataataaggacttcagtgtgattgtc caagttcctccatccatccgtaccaatggacctactgaacgttcagtgattctccacaag cccatgagtctagactgtatctccagtggaattcctcctcccaccattacctggcttaaa aatggacgaccagtcgacgcaactagtgagcacctgcagctggagtcagcaggcaggaca ctaaagattacagaggcaagactggaggattctgggaaattcacttgcctggccactaac gcagctggggaagctcagcagcacataagactcagcgtccacgagcctcccagtatcccg tcctctggagagaccattaaccagaccattctgtcaggcttttccactgagctcgagtgc aaggccgcgggcagcccattacctgctatcacttggtacaaagatggccgacctctgacc agtgcagctggtgtgacgttacggaagcgtggccaaatgctggagattgaacgagcacag ctgtctgatgctggcatatacagatgtgtcgctgtaaacctggctggagctgctgagata tcgcacagacttcaggtccttgtgcctccggtcatctccagccgaggcggtacggtaact gttgtcgtgaatgaagccgtcaggttggagtgtgaggctacaggggttcctgctcccagt atcacatggctcaaagacggcagccctgtggcaagtctttcacatggcatacaggtgttt gctggtggcagagtgctgtccctggatagcgcacaggttagcgacacaggcaggtacacc tgtgtggctgtcaacgctggaggagaacagcacagagactatgacctgaaggtttatgtg ccacctaacatccagggcgaggaggtgaatgctacagtgatgcttggtcagcccgtggag ctgcactgccagagcgatgcagtccctccacccaccctgtcctggctcaaagatggccgc ccactctttaggaagcctggtctgactgtgtcagcagatgtcagtctgcttaagatcagc agggtgcatgtgcaggattcaggcagatatacctgtgaagccacaaacgttgctggcaaa acagagaagaactataacctcaatgtgtgggtgtcccccagtatccgaggctctgaggag gtgtctcctctgacggtagttgaaggcagtctcatcactcttgtgtgtgagtccagtggc ataccgcctcccagtctcacatggacgaaggatggttctgaagtgaaatctgaccagcgg gtcaggattttgtcaggaggtcgtcagctgcagatctccagcgctgagaagacagatgct gcttcttacacctgcacagcctccagtgcagctggcaccatctccaaggagtacagcctg caggtttatgtccgtccttccatcagacgcaccgaaggcgacgctgatgaggtcattgtg ataaagggaggcgatgtgacgctgcaatgtgatgcagaaggtgtgccgcgacctgccgtc acgtggctgaaagacggacggccgatcacaggccaccatggtgcaaaggtcctgaatgag gggaggttactgcagattaaagatgccaaagtgtcagacacgggacgctacacgtgcatc gctgttaacgtggcaggacaggctgacagcaagcatgacatcagcgtgcacgtcccaccg agtataactgggcaggttcagtttccagaaaatgtgagtgttgtcatgaggaacccagtt ggtctgatctgtgaggcctctggcatccctcttcctaccatctcctggttgaaggacggt cagccaattaaaacgactagttcagcgcgcatcctttcaggtggccgcagcctgcgtctg atgcatgctgcagcagcggatgctgggagatacacttgcatcgtgtctaacagcgctggg gaggagaggaagacctttgaccttgacatccttgttcccccgagcattgtggaggaggga actgtggtggatactaaagtgaaggagaaacacaacatcactctcacttgtgaagcatca ggtaatcctgtacctgagattaaatggctgaaggatggacagctgctggtgcctgacggg cattaccaagttctgtctcatggccgtttcctccaaatctctggtgcccaagtcgcagac actggcaggtacagctgcctggcatctaacagtgcaggagaccgcagtcggcattacaat cttaatgtcctggtttctcccaccattgctgggtcaggccctgacatttctgcagaggag gttacagtaaccctgagcagccctacctcactggtgtgtgaagtccagtcttaccctcct gctctgatcatgtggctcaaagatggcactccatttgaatccagtcgcaacgtcagagtc cttccaggtgggcaaacgctgcagattctcaatgctaaacaagaggatgctgggaggtat acatgcgtggccactaatgaggctggagagacactgaagcactatgaggtcaaggtttat gttcctccacagattaataagaatgacattcccggggaaggactggcccctaaagaggtc aagatcaaggttaacagcagcctgactttggagtgtgtcgctcaggcctttcctaccccc gcactgcagtggtataaagatgggcagatcctgcagtcagatgaccacgtgtctattaca gccaacggtcggatcgttcagatcaaacatgctcaggtgtcagacactggccgctacacc tgtgtagccactaatatagctggagaggatgagaaggactttgatgtaaatatacaagtt ccacctaattttaacaggcctggtgcagatggtgataccacatcttcctcgggctttgga gttgatgcacgagacgtgatactcaacaatcccatctccctgtactgtgagaccaacgcc gtcccccctccgaccctcacttggtacaaagacggacatctgctgacatcgaatgacaaa gttctgatcctgccaggagggcgcgtgctacagattcccagggcccagattgaggactca ggcaggtacacatgtgtggctgtcaatgaagcaggcgaggactccatccagtatgatgtt agagtgctattgcctccaaccatacgtggaacagacagcgacttgcctgatgaagtcaca gtgctggtcaataaaactgcccaactggagtgtcatgtggatggaaacccggcccccaaa attagctggtttaaggacaaccagccaatcacctccaacagcttgcatagaattctgtcc aatgggcgagcacttcagatattgacggctcaggtatcggacacagggcgttatgtgtgt gcagctgaaaatgtggctggaagtgcagaaaaaatatttaatctcaatgttcatgtgcct cccaccattatcggcctgagttctgagaatgtgacagtggtcgcgaacaactttgtggct ctctcctgtgaagctactggcttccctcctccaacactgggctggctcaatgacaggggc ccaattcaagctaacaccaatgcactcatcatgccgggtggacgtactttacaaatcctg aaagcaaaagtgtccgacggaggaaagtacagctgtgtggccctgaacgcagcaggagag gctcacaaacacatctacctcactgttttcgttcctcccagcatccgagacaatagcggg gactctcctgtggtggtgaatgtgctcgttgggaaatctgtaactctggagtgtgaatcc aatgctgtccctcctcccgtcatcacttggtataagaacggcagagtggtgacagaatca gccaacctgcgcgttttggctgagggacagatcctccagatcgaaggttcagaggtgtct gatacaggacagtacgtttgcatggccaccaatgttgccgggcaagtggacaagcacttc cacttgaacatctatgtacctcccagtatcgatggcccagcagaggagacagttgtagaa accatcagtaatccggtcatctttaactgtgacgcgagtggaatccctccacccacgctc acttggctgaaaaacgggcgcaccatagagaactcagagtctttggagatgcacatcttc tcagggggcagcaaactgcagatcgcacggtcacagctcgctgacagcggcacttacaca tgtgtggcctccaacgtggagggcaaggcctacaagaggtaccgcctaaccatacaagtt cctcccagtatctctggatcagagctacccagtgaaatgggagtcctgctaaatcaaacc attcagttggtctgtcaagctcagggagccccaactccgaccatccagtggctgaaggac ggggaagccatcaacagtacgggaagcaaggcgctcaggatcagtggaaatggcagcaaa ctcactgtactacgagctcagactgctgacagcggcaagtacacctgtgtggccactaac gctgcaggagaagaggacaggatatttaatctgaacgtgtatgtgccgcctgtgatcgta ggcaacagtggggctgttgaggagctcgcagcagttctggacagttctgtgagcatcgag tgcgtcgcaacaggctcccccctgcctcagctaaactggctgaggaatggcctgcctctg ccagtctcctcacacatacgtctcctctctgctgggcaagtccttcggatggcacgcatc caggtgtctgatggtggacgatatacctgcgttgcatcaaacagggcaggagtggacaac aaacattataacctgcaggtgcacgtccctcccggtctggatggagcagggagcacagag gatgtgactgtggtcggaggaaacttggcttctctgctgtgtattgctgatgggacccca acgcccaccgtttcctggctcaaagatggagcaactctagtccccgaccgccacgtcgtt ctcctaaactcgaacaccaaccttcgtattagacaggctcaggttggcgacacgggacgc tacacctgcgtggctaacaacactgctggtgaagcgagacgtcacttcaaccttaaagtt atggatcctccgcgcatcgagggctctggtgtacctgcagaagtgtctgtggtggttaat aatgtcctggagctccactgtgaggccgcaggtatacctacaccctctctgacctggctc aaggatggacgcccgctcccacagacagacagcctgcgcctcctccagggaggaaaggtg ctccatgtggcctcagcacagctggaggacacaggcagatacacctgcttagcaaacaat ccagcgggagatgatgacaaggacttcctagttcgagtgcatgttcctcctaacattgtg ggagacagtacacctcgggatatgtcagtgctgcagaacagacaggtgactttagagtgc aagtctgatgctgttccacctccaacgctgacctggctcaaagatggccaaccactgcag gcctctgctcgtgtgcgtgttctgtctggtggccgctacttgcagatcaacatggcagag ctcagcgacagagctcagtacacctgcgtggctagtaacatcgctggccagaccacacgc aagtttaacctgactgtcaatgtggccccagctatcaaggacggaccccagtcagtgacg gtgcacgtcaacaagccagcaatgcttgaatgtgtagtgagtggagtcccaccacctcag gtcacctggaggaaacatggagcaatattggcaggaaacaatcccaggtacacgtttgca gaggatgggtctttgcgcatcaactccgctcaggtgaccgacaccggtcgctacctctgt atggcaaccaatcaggctggaactcaacgcaagagagtggatctgcaagtatatgtgcct ccttccatcgctgatggtcgcactaatgtcacagttatagtcaacgttcagaccactctg tcttgtgaggctacaggcatacctaaacccactgccagctggaggaaaaatggccgactt ataaacacagaccagaaccagaacatatacagattactgtcatcgggctcgctggtagtt atagcgcccacagtggaggacacggctgtgtaccagtgtgttgcctctaatgaggcaggt gaagacaccagatccatcaacctcactgtgaacgttcctccgtcaatagcagatgaactc acagagttagtcgtgaccaggctgtccccggtggtcattccatgcactgcgtctggcatc ccagagcccacaatccactggagcaaagatggcatgaagctgcccgaagagggtcttgga tatagcatcctggcaacaggcccgatagagatcacctcagccgagctaactcatgctgga cgctactcatgtacagctcagaacgctgcaggctccacccaccgccacgtgcagctcaca gtccaggagcttccagtaattcagtcccatccatcagcactggatgtgatcctgaataac cccgtaagtctgccctgcagggccacaggctcacccagccctaccattacctggcagaag gagggcatcaacgtacccagtacaggtggtaggtccaccatactccctaatggaagtctg cagatctccaaggcaacactgtcagactctggaatgtacatatgtgtggctcaaaaccct gctggcactgcgcttggcaagaccagactcagagtgcaagtccctccagtgatcagctca gacactcgggaatatttggcacctgtggactcctctgtgatgctgcagtgccaagctgac ggctcccctcccccctcggtcacgtggcacaaagacgggcgcgtgctgagtgaaactgta cgcctgagggtcctcagttcaggatctctgcagatcgccttcattcagccgagtgatgcc gggagatatacttgcactgctgccaatgcagcgggcactgtcagcttggaaatgagcctt actgtgcagattcctccattaattcgtggtggagagcaggaggtcgtggtggtggaaaac agtcaggtccagcttgtgtgtttggcagagggtgtccctcagccaaaactgtcctgggaa aaggaaggtagtcctgtcagtgaaagcgtgggggagtatacaatcctgccatctggtgag ctggttattgacagtgctcagcctgaagatgcaggaagttacacctgtgttgccactaat tcagtcggccaggacagttggaccgtcaccctgttggttcatacacatcccatcttcact gagcttcttggagacgtggccctgaacaaaggagagcgcctcatgctgttctgtggagtc agtggcatccccctacccagtatcacttgggcctttaataacaacatcatcccagttcac tacgatcaaacaaacggtcacagtgagctggtgatcgagagagtgagcaaagacgacgcc ggcacctacacctgtgtggcagaaaatgatgtgggaaccatcaagtcgctggcctttgtc tatgtcaaggagcctcctgtcattgatggggaccttcactccaaccgcattgaacccctg ggcggtaatgcaatcctgaactgtgaggttcgaggagaccccctgccaaccatccagtgg agcaaaaatggaataaacatccagatcagcaaccgaatccgtcaactggacaacggctcc ttggccatctatggcaccgtgagtgaagatgcgggaaactacatgtgtgtggcgacaaat gatgctggtgtggtggagagaagtgtcacacttaccttacacagtgcacccgcaatcatt gtagaacccgtggagaccgtagtggatgctggaaccacggctgtgctcaactgtcaggcg gagggtgagcctacgcccatgatagagtggtctcgtcaggggcgcccccttctgggcaac aaccgcttctctgccttatctaatggctccctcaggatcatcagtgcacaaaaggaggac acagctgagtatgaatgcgtagcaagaaacctgcttggatcagtgctggtcaaggtcact cttaccgtacgggtccatggcggcttctcggagtgggcagagtggggtccttgcactgtg tcatgtggtgttggcaaccagaagaggctcaggcagtgtaacaaacctttacctgcaaat ggaggccgccactgtgcaggatcagacacagagacacgcagctgtcaaggaaaaccctgc ccagtggatggcaactggtcagaatggtctctctgggaggagtgttcacgtagctgtggt gagggcaacagaaccagggtccggacctgcagcagtcctccgcctcagcatggaggcagg ccgtgtgaggggaaggcagtggacgtggtcatgtgcagggtcagaccatgtccagtggga ggtaactggggttcttggctaccgtggagcccatgcagcgagacctgcggtaggggcgtg cagtccaggatccgcctctgcaacaaccctcctccagcatttgatgggtcacagtgcgtg ggcacagacacccaaacacaaatgtgcaaggagaaaccttgtcccgtggatggaaagtgg tcgtcctgggtgagctggggagcctgcagtatttcctgtgggggtggtactagacagagg acacgcctctgtgccagccccgcccctcagcatggtggcagacagtgtgagggcaacgat gtgcaaatcgacttctgcaacagcgacccctgccccatcagtggtaactggggtccatgg agcagctggggcagctgcagcaagacatgtaacggaggtcagatgaggcgctacaggacc tgtgacaaccccagacccgcctacggtgggagagcttgtgcaggtgctgatacacagata cagagatgcagcaccgtcaagtgccccgttgatggtacctggggttcatggcagccatgg gaagaatgttctgcttcctgcggaggaggacagaggacacgtgttcggctctgtgacagt ccatctccaagcgacggtggccggccgtgtccaggagactctactcagctgtccaggtgc aatactcaggcctgcccaggtgggcccctgaaggcccgaggaagcattatagggaacatt aatgatatcgagtttggcgtctccatcctcaatgcctccatcaccaacagcgagtatggc agcagaatcatcaaagccacaatctctaatgtaccaaggacgttaggtcctgcgatgagg aagctcatctccatcctgaaccccgtctactggaccactgcgcatgaagtaggagaggcg gtcaatggctacacgctaacagggggtatcttcaggcgagagacacaggtggagtttgcc acaggcgagatcctgaggatgacccacattgtcaggggcctggactctgacggcgctttg cttttggacatcgttgtgaacggacacatcctacagctgccttcacatgctctcatcagc atcaaggactacacagaggactacatccagacgggaccaggtcagctctacgctctgtcc actcgcatgttcagcatcgacaaagaaagcgtgccctacacctggaaccacactgtctcc tatgatccgtccaaggggaagatgccttacctggtagagacgctgagggccgcagccatc agtgcacactaccacccactggaggaagtcttggagtatagcatacaagctagtatctcc aaaggtgatcgcagtaaccagtgtcctcgtggcttcactttggtggctgccgggccttac tgtgcagatgagaatgaatgtgaggttgggaacccgtgttcacatgcctgccacaacaca atgggcacctactactgctcctgtccccgaggcctcaccatctcagccgacgggaggacg tgtcaggacatcgacgagtgttcgctaggtgacaatgtgtgccacgacgcagaagactgc gagaataccattggctcttacagatgcgtcatgcgctgtgggcgtggcttcaggagaacc gctgacggctacagctgtacagatgtgaacgagtgccaggagtcaaatccctgtaatcag cgttgtttgaataccatcggtagttaccgctgtgcctgtgagccaggctttcttctcagg agcagacgctgcatagatataaacgagtgcaggcagagggtttgtcgctctgatcagcag tgtaaaaacacacgcggtggttacatctgtattgacctctgccccagtggtatgaccaag ggtggcaatggaacatgtgtggacgttgacgagtgcagcgacggcacccatcagtgcaga tacaaccagatctgcgagaacaccagaggcagctaccactgtacctgtccccgtggttac agatcccagggagtaggacggccctgcgtcgatgtaaatgaatgtgagcggcgtcctcag ccttgcgcccaccagtgcatcaacactcccggcagcttcaagtgcgcctgccctccgggg cgccacctgctgggggatggcaagtcctgcgctgggcttgagcggctgcccagctacgaa agttactcgtacagtttccgcacctctcagtccgctcccggcggcggctccagccagatg ctctaccacaacttggcctcccagagctaccactcctacgcagcccccgtgagggggcgc tacaggagtcggagccgcagggagatgcgtgtgcattcctcacatcagggcgtcctcgct tgtcagcaggggtttgagcccaggggtcaccgctgcttagacatcaatgagtgtgaagtg agggacacctgtcagcacgagtgcacgaacacaccaggaagctacaggtgtctctgtccc gctggttaccgcctcatgaccaacggcaagacttgtcaagacacagacgagtgcctggaa cagaacatccagtgtggagtgaatcgaatgtgcttcaacatgagaggaagttaccagtgt attgacactccctgtcccccaaactaccagagggacccagtcacagggttctgtctgaga aactgccagccaaatgacctggagtgcgcactgagcccgtacgccttggagtacaagctg ctgtcgcttccctttggcatcgcagccaaccaggacctcatcaggctggtggcctacaca caggatggagtgatgcaccccaggaccagtttcctggtggtggacgaggatttcgcgtta ccgtttgctctgcgagatgagaacctaaagggagtgctgttcaccacgcggccgctacga gagccccgcacgtaccgcatgaaggtccgagccctgtcctacagtgaagacggaggcatc gagtaccagacgaccttcatcgtctacatcgctgtctctgcctacccctactga

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