KEGG   Oreochromis aureus (blue tilapia): 116335111
Entry
116335111         CDS       T07295                                 
Symbol
erbb2
Name
(RefSeq) receptor tyrosine-protein kinase erbB-2 isoform X1
  KO
K05083  receptor tyrosine-protein kinase erbB-2 [EC:2.7.10.1]
Organism
oau  Oreochromis aureus (blue tilapia)
Pathway
oau04010  MAPK signaling pathway
oau04012  ErbB signaling pathway
oau04020  Calcium signaling pathway
oau04510  Focal adhesion
oau04520  Adherens junction
oau04530  Tight junction
Brite
KEGG Orthology (KO) [BR:oau00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    116335111 (erbb2)
   04012 ErbB signaling pathway
    116335111 (erbb2)
   04020 Calcium signaling pathway
    116335111 (erbb2)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    116335111 (erbb2)
   04520 Adherens junction
    116335111 (erbb2)
   04530 Tight junction
    116335111 (erbb2)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:oau01001]
    116335111 (erbb2)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:oau04147]
    116335111 (erbb2)
   04090 CD molecules [BR:oau04090]
    116335111 (erbb2)
Enzymes [BR:oau01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.1  receptor protein-tyrosine kinase
     116335111 (erbb2)
Protein kinases [BR:oau01001]
 Receptor tyrosine kinases (RTK)
  EGFR family [OT]
   116335111 (erbb2)
Exosome [BR:oau04147]
 Exosomal proteins
  Exosomal proteins of breast cancer cells
   116335111 (erbb2)
CD molecules [BR:oau04090]
 Proteins
  116335111 (erbb2)
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Recep_L_domain GF_recep_IV Pkinase Furin-like TM_ErbB1 ABC1 Haspin_kinase Tcell_CD4_C
Other DBs
NCBI-GeneID: 116335111
NCBI-ProteinID: XP_031614574
Ensembl: ENSOABG00000022580
LinkDB
Position
LG8:complement(16883993..16913666)
AA seq 1311 aa
MRCKNFISVPPRWTRSAGSAQMEAARSLLFVGAVLLGVTGASGREVCRGTDMKLALPSSL
ENHYETLRLLYTGCQVVHGNLEITHLHGNLDLSFLQGIVEVQGYVLVAHVSVSLLPLDSL
RIIRGSQLYNSSYALAVLDNTHAGQGLRTLRLRSLTEILLGAVYIWGNPQLCFPDPQNIN
LTDILDEQNGRAKEHQLQPRPPNCPSCSPACGKRCWGETPQDCQILTRAKCASGCQRCKG
PLPNDCCHLQCAAGCTGPKDSDCLACRHFNDSGVCKENCPLPTTYDPVTFQSLSNPHGKF
NFGATCVKTCPYNYLALEVACTLSCPPNNQEVVVTQPDGTETQKCDKCEGDCPKVCFGPS
TDNNGVTDSSSSSIAVVTPSNVEEFNKCTKIFGSLAFRSESFSWDPAKNTSGLTLEQLSA
FRTLEEITGYLYIDAWPEQWTNLSVFENLKVIRGTMLYKGVFSLAIQNLHIESLGLRSLR
SVSGGLVLIYNNTQLCYTNSVPWQNLLHPTQGPHRIVSHNQDPAVCEKERNVCHSLCKAG
CWGPGPSQCVSCQTFQRGTECVEQCDLYQGPVREYIDGSKCVACDPQCRPLNGSESCHGP
GAQHCTECRNFQDGENCVDRCPSGVKGDLHTVWKYSNATGHCLPCKTNCTPPCTVKDERG
CPIDTRTGPGTSIAAAVGGVVLFIILLALLVFYLRRQKKLKRKETMRRILQEHELVEPLT
PSGASPNQAQMRILKETELKKLRVLGSGAFGTVYKGIWAPDGENVKIPVAIKVLRENTSP
KANKEILDEAYVMAGVASPYVCRLLGICLTSTVQLVTQLMPYGCLLDYVRENKDRIGSQF
LLNWCVQIAKGMSYLEEVRLVHRDLAARNVLVKNPNHVKITDFGLARLLDIDETEYHADG
GKVPIKWMALESILHRRFTHQSDVWSYGVTVWELMTFGSKPYDTIPARDIPEVLEGGERL
PQPLICTIDVYMIMVKCWMIDPESRPRFKGLVNDFSAMARDPPRYVVIQNDEEMSKCSPV
DSEFYRMLLREDENIGEMMDPEEYLVPNIRKGDEPQANGLSRHQSYRQSRDHSLDMDPSN
TAGPRNLHSSLTGISHTQYPTSPMAASASNSVWPQYPMLARSTSAGGQSDSVFLDAPTDG
HSLAPASPGRYSKDPTFPNGSKDDLETDGCNGFPHPYLHHSLPRRSHAIQNHPLPEYVNQ
EIQDLRPGFPERPSTLPRKSRIDRRLPNGLSSGHSVENPGYLIPVNSTSPAFDNPYYLDL
GPKAIPGAVAGDGPTGLESNGGVTRHMNGFVTPTAENPEYLGLADTWSGHT
NT seq 3936 nt   +upstreamnt  +downstreamnt
atgagatgcaaaaacttcatctctgttccccccagatggactagaagcgccgggtctgcg
cagatggaggcggcgagaagtttgctgtttgtcggggccgtgctgctcggagtgacgggc
gcttcaggcagagaagtctgtcggggtacagacatgaagctggccctgccctccagcctg
gaaaaccactatgagaccctgaggctgctctacaccggttgccaggttgttcatggaaac
ttggagattacacacctccatggaaaccttgacctctccttcctgcaggggattgtggag
gtacagggttatgtactcgttgctcatgtttctgtgagcctgttgcccttagacagcctt
cggatcataagaggcagccagttgtacaactccagctacgcgctggctgtgctggataac
actcacgccggtcaggggctgaggacgctccggcttcgtagcctcacagagatcctgctg
ggcgcagtgtatatttgggggaacccccagctgtgcttcccagacccccagaacatcaat
ttgacggacatcttggatgagcagaatggccgcgccaaggaacaccaactgcagcctcgg
cctcctaactgtccaagttgttcgcctgcatgcgggaaaagatgctggggagagactcct
caggattgccaaattctgacccgagctaaatgtgcgtctggctgccagcgatgtaaaggt
cctctacccaacgactgctgtcacctgcagtgtgcagctggatgcactggacccaaagac
tcagactgtctggcttgtcgtcacttcaacgacagcggtgtatgtaaagagaactgtcca
ctgcccaccacctatgaccccgtcacgtttcagtccctatccaacccacacgggaagttt
aactttggagcgacctgtgtcaagacgtgtccttataactatctggcgttggaagtggcc
tgtactttatcttgccccccaaacaaccaggaagttgtcgtcacccaacctgatgggacg
gagacgcagaaatgtgataagtgtgaaggagactgtcccaaagtgtgtttcggcccgagt
acagacaacaatggtgtcaccgacagcagcagcagcagcatcgccgtggtaacgccttcc
aatgtggaggagttcaacaagtgtacgaagattttcggtagcctggccttccgctctgag
agcttctcatgggatcctgcgaagaacacctcaggcctgactttggagcagctgagtgcc
ttcaggactctggaggagattacaggttatctctacattgatgcctggccagagcagtgg
accaacctcagtgtgtttgagaacctgaaggtgatcagaggcacgatgctctacaagggt
gtgttttcactggccatccagaatctgcacatcgagtctctcgggttgcggtcgctgcgc
agcgtcagtggaggtttggtcttgatttacaacaacacacagctgtgctacaccaactca
gtgccatggcagaatctcctccatcccacccagggtccgcaccgcatcgtcagccacaac
caggaccctgcagtctgtgagaaagagaggaatgtttgtcactcgctttgtaaggcgggc
tgttggggtccggggcccagccagtgcgtgtcctgccaaactttccaacgtggcaccgag
tgtgtagagcagtgtgatctctatcaggggcccgtacgtgaatacatagatgggtctaag
tgtgttgcctgtgatccacagtgtcgacccctcaatggctcagagtcctgccacgggccg
ggtgctcaacattgcacggagtgtcggaacttccaggatggcgaaaattgcgtggatcgg
tgtcccagtggcgtgaagggcgatctgcatactgtgtggaaatacagcaacgccacggga
cactgtctgccatgcaagaccaactgcacgccaccctgcactgtgaaggatgagcgaggc
tgccccattgataccaggacaggacctggcacgtctatcgcggctgcagtgggtggggtg
gtgctcttcattatcctgctggctctgctggtcttttacttgaggagacagaagaagcta
aagaggaaggagacaatgaggaggatcctgcaggagcacgagctggtggagcctttaacg
ccgagtggtgcttcacccaatcaagctcagatgcgtatattgaaagagaccgagctgaaa
aaactcagggtgctgggttcgggggcctttggcactgtttacaagggaatttgggctcct
gatggggaaaatgtgaaaatcccagtggccattaaggttttgcgtgagaacacctcacca
aaagccaacaaagaaatcctcgatgaggcgtatgtgatggcgggcgtcgccagcccgtac
gtgtgtcgtctcctggggatttgtctcacctccactgtgcagctggtcactcagctgatg
ccgtacggctgcctccttgactacgtcagagagaacaaggaccgcattggttcgcagttc
ctactcaactggtgtgtccagattgccaaggggatgagttatctggaggaggtccgtttg
gtccacagagatttggcagcccgcaatgtcctggtgaagaaccccaatcacgtgaagatc
actgactttggtctggcccgtctgcttgatatagacgagactgagtatcacgccgatgga
gggaaggtgccaatcaaatggatggccttggagtctatcctgcacaggaggtttactcac
cagagtgatgtgtggagctacggggtaactgtttgggagctgatgacatttggctctaag
ccctacgacacgattccagcaagagatatcccagaggttttagaggggggcgagcggctt
ccccaaccccttatctgcaccattgatgtctacatgatcatggtcaaatgttggatgatt
gatcctgagagcaggccgagattcaaaggcctggtcaatgattttagtgccatggctaga
gatccacctcgctatgtagttattcagaatgatgaagagatgagcaagtgcagcccagtg
gacagcgagttttacaggatgcttctgagggaagatgaaaatattggggaaatgatggat
cctgaggagtacctggtgccaaatataaggaaaggggacgagccccaggccaatgggcta
tccagacaccagtcatacaggcagagcagagatcatagcttagatatggacccttccaac
actgctgggcctcggaatcttcactcctccctgactggaatcagccacacccagtaccca
acctcaccgatggcagcaagcgcctctaacagtgtgtggcctcagtatccaatgctggct
cgcagcacctcagctggaggtcagtctgactctgtcttcctggatgcacctacagacggc
cactccttggcaccagccagccccggacgctacagcaaagaccccaccttccccaacggg
agcaaggatgacctagaaactgatgggtgtaatggttttccccatccttatcttcaccac
tcactaccccggcggagtcacgccattcaaaatcatcccctgccagagtacgtcaaccag
gaaattcaggatctcaggccagggttccctgagcggcccagcacactgcctcgaaaatcc
agaatagaccgccgccttcctaacggcctaagttcaggtcacagtgtggaaaacccaggg
tatttgatcccagtgaactccacctctccggcctttgacaacccatactatctggacctt
ggacccaaagcgattcccggggctgtggcgggggacggccccacaggactggaaagcaac
ggaggagtaaccagacatatgaacggttttgtgacaccgactgcagaaaatccagaatac
ttaggattagcagacacttggagtgggcatacttga

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