Oceanicaulis alexandrii: ABWI01_12050
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Entry
ABWI01_12050 CDS
T10771
Name
(GenBank) thiamine pyrophosphate-dependent enzyme
KO
K00166
2-oxoisovalerate dehydrogenase E1 component subunit alpha [EC:
1.2.4.4
]
Organism
oax Oceanicaulis alexandrii
Pathway
oax00280
Valine, leucine and isoleucine degradation
oax00640
Propanoate metabolism
oax00785
Lipoic acid metabolism
oax01100
Metabolic pathways
oax01110
Biosynthesis of secondary metabolites
oax01210
2-Oxocarboxylic acid metabolism
Module
oax_M00036
Leucine degradation, leucine => acetoacetate + acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
oax00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00640 Propanoate metabolism
ABWI01_12050
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
ABWI01_12050
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
ABWI01_12050
Enzymes [BR:
oax01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.4 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
ABWI01_12050
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Motif
Pfam:
E1_dh
OxoDH_E1alpha_N
TPP_enzyme_C
DXP_synthase_N
BT_2262-like_C
Motif
Other DBs
NCBI-ProteinID:
XHC19891
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Position
2486680..2487909
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AA seq
409 aa
AA seq
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MSNGQTRFHVPTPPYRPGDEPDFAHLDLQKAGEASRPDPAASWQETQDLATGLVGVLDHN
HQAVGAWNPELSPEVLREGLSHMVLTRIYDERMLKLQRQGKMSFYMKSTGEEAVAVAAAM
ALKPTDMVFPSYRQQGILFARGRNIVDMMCHCISNSRDNLKGRQLPVHYTWAEGSFFTIS
GNLGTQFPQAAGYAMACAYKGEDQIAASWIGDGTTAEGDFHAGLTLASTYRAPVIFNVVN
NQWAISSNQNIARGDAPTFAAKGLGYGLASIRADGNDFLAVYAATQWAAERARQGKGATV
LELFTYRADAHSTSDDPTKYRPKTEFDRWPLGDPIERLKQHLIGRGEWDETRQAKLEEQM
TALVVKSYKEAESHGTLHEGPLSPTESIFEDVYAKPDWRLRRQRQDLGV
NT seq
1230 nt
NT seq
+upstream
nt +downstream
nt
atgtcgaacggacaaactcgtttccacgttcccaccccgccatatcggccgggagacgaa
cccgacttcgctcacctcgatcttcagaaagcgggcgaggcgtcacgccctgatcccgcc
gcgtcctggcaagagacccaagatctggcgacagggcttgtgggcgtgctggatcataac
catcaggccgttggcgcgtggaaccccgagctcagcccggaagtgctgcgcgaagggctg
agccatatggtgctcacccggatctatgacgaacgcatgctcaagctgcagcgtcagggc
aagatgagcttctacatgaagtccacgggcgaggaggcggtcgccgtcgcggcggccatg
gctcttaagcccaccgacatggtgttccccagctatcgccagcagggcatcctgttcgcg
cgcggccgcaatattgtcgacatgatgtgtcattgcatctccaacagccgcgacaatctc
aaaggccgccagctgccggtgcattacacttgggctgagggcagcttcttcaccatctca
ggcaatctgggcacccagttcccgcaagccgccggatacgccatggcctgcgcctataag
ggcgaggatcagatcgcggcgagctggattggcgacggcaccacggcggaaggcgatttc
cacgccggtctgaccctggcgtccacctatcgcgcgccggtcatcttcaatgtcgtcaac
aatcagtgggccatctcgtccaaccagaacatcgcccgcggcgatgcgccgacctttgcg
gcgaagggcctggggtacggcctggcgtcgatccgggcggacggcaatgacttcctggct
gtgtacgccgccacccaatgggccgctgagcgcgcgcgtcagggcaagggcgcgacggtg
ctggagctgttcacctaccgcgcggacgcgcactccacctccgatgaccccaccaaatac
cgccccaagaccgagttcgaccgctggccgctgggcgatcccatcgagcgcttgaaacag
cacctgatcggccggggcgagtgggacgagacccgtcaggccaagctggaagagcagatg
acggcgctggtggtgaaatcctataaggaagcggaaagccacggcacgctgcatgaaggc
ccgctttcgcccaccgaaagcattttcgaagacgtctacgccaagcccgactggcgcctg
cgccgtcagcgccaggatctgggagtttaa
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