Afipia carboxidovorans OM5 (Mississippi): OCAR_5296
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Entry
OCAR_5296 CDS
T00783
Symbol
leuA
Name
(GenBank) 2-isopropylmalate synthase
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
oca
Afipia carboxidovorans OM5 (Mississippi)
Pathway
oca00290
Valine, leucine and isoleucine biosynthesis
oca00620
Pyruvate metabolism
oca01100
Metabolic pathways
oca01110
Biosynthesis of secondary metabolites
oca01210
2-Oxocarboxylic acid metabolism
oca01230
Biosynthesis of amino acids
Module
oca_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
oca00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
OCAR_5296 (leuA)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
OCAR_5296 (leuA)
Enzymes [BR:
oca01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
OCAR_5296 (leuA)
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Gene cluster
GFIT
Motif
Pfam:
HMGL-like
LeuA_dimer
HCS_D2
Motif
Other DBs
NCBI-ProteinID:
ACI92428
UniProt:
B6JB87
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All DBs
Position
1279258..1280817
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AA seq
519 aa
AA seq
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MTSPSTSDKDRVVIFDTTLRDGEQCPGATMTHEEKLEVAEMLDTMGVDIIEAGFPIASVG
DFEAVAEIAKRANNAVIAGLARAIPADIVRAGEAVRHAKRGRIHTFVSTSPIHLAHQMRK
SEEDVLGIITATVAQARNLVDDVEWSAMDSTRTPIDYLCRCVETAIAAGATTINLPDTVG
YAVPEEYRRMFKVIRERVPNADKAVFSVHCHDDLGLAVANSLAGVEGGARQIECTINGIG
ERAGNAALEEVVMAIKTRGDVMPYWCNVESTTLTRASKVVSAATSFPVQYNKAIVGRNAF
AHESGIHQDGVLKNAQTYEIMTPESVGVKQTSLVMGKHSGRHAFQHKLRELGYELADNQL
QDAFVRFKALADRKKDIYDEDIEALVDQELAQTHDRLRLVSLTVIAGTHGPQRATMKVEV
DGKVRIDEAEGNGPVDAVFNAVKTLVPHEAKLELYQVHAVTAGTDAQAEVSVRLSQDGRS
VTARSSDPDTLVASAKAYLSALNKIISRQQREAPVAAAS
NT seq
1560 nt
NT seq
+upstream
nt +downstream
nt
atgacgagcccctccacgtccgacaaggaccgcgtcgttattttcgacaccacgttgcgc
gacggcgagcagtgccccggcgccaccatgactcatgaggagaagctggaagtcgccgag
atgctcgacaccatgggcgtcgacatcatcgaagccggcttcccgatcgcctccgtcggc
gacttcgaggcggtggccgagattgccaagcgtgccaacaacgcggtgatcgccggtctc
gcccgtgcgatcccggccgacattgtccgtgcgggtgaagccgtgcggcatgccaagcgc
ggtcgcatccatacgttcgtatcgacctcgccgatccacctcgcgcaccagatgcgcaag
agcgaagaggacgtgctcggcatcatcaccgcgacggtggcgcaggcgcgcaatctcgtc
gatgacgtcgagtggtcggcgatggattcgacccgtacaccgatcgactatttgtgccgt
tgcgtcgagaccgcgatcgcggcgggcgcgacgacgatcaacctgcccgataccgtgggt
tatgcggtgccggaagagtatcgccgcatgttcaaggtcatccgcgagcgggtgccgaac
gccgacaaggcggtgttctcggtgcattgccatgacgatctgggcctggcggttgcgaac
tcgctcgccggcgtcgagggcggcgcacgccagatcgaatgcaccatcaacggcatcggc
gagcgcgccggtaacgccgcgctggaagaagtcgtgatggcgatcaagacccgcggcgat
gtgatgccttactggtgcaacgtcgaatcgacgacgctcacccgcgcctcgaaggtggtg
tcggcagcgacgtcgttcccggtgcagtacaacaaggcgatcgttggccgtaacgccttc
gcccatgagagcggcatccatcaggacggcgttctgaagaatgcgcagacctatgagatc
atgacgcccgaaagcgtcggcgtgaaacagacctcgctggtgatgggcaagcactccggc
cgtcatgccttccagcacaagctgcgggaactgggctacgagctcgccgataaccagttg
caggatgccttcgtgcgcttcaaggcgctcgccgaccgcaagaaggacatctacgacgag
gacatcgaggcgctggtcgatcaggagctggcgcagacgcatgaccgcctgcgtctggtg
tcgctgacggtgatcgcgggcacccatggcccgcagcgcgcgaccatgaaggtcgaggtc
gacggcaaggtgcggatcgacgaggccgagggtaacggcccggtcgatgcggtcttcaac
gccgtcaagaccttggtaccgcacgaggcgaaactggagctgtatcaggtccatgccgtc
acggcgggaaccgacgcgcaggcggaggtttccgtccggctgtcgcaggatggccggtcg
gtgacggctcgcagttcagacccggatacgctcgtggcctcggccaaggcctatctgagc
gccctcaacaagatcatttcccgccagcagcgcgaggcgccggtagctgcggcaagttga
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