Ovis canadensis (bighorn sheep): 138415014
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Entry
138415014 CDS
T11679
Symbol
TOP3A
Name
(RefSeq) DNA topoisomerase 3-alpha isoform X1
KO
K03165
DNA topoisomerase III [EC:
5.6.2.1
]
Organism
ocan Ovis canadensis (bighorn sheep)
Pathway
ocan03440
Homologous recombination
ocan03460
Fanconi anemia pathway
Brite
KEGG Orthology (KO) [BR:
ocan00001
]
09120 Genetic Information Processing
09124 Replication and repair
03440 Homologous recombination
138415014 (TOP3A)
03460 Fanconi anemia pathway
138415014 (TOP3A)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03032 DNA replication proteins [BR:
ocan03032
]
138415014 (TOP3A)
03400 DNA repair and recombination proteins [BR:
ocan03400
]
138415014 (TOP3A)
Enzymes [BR:
ocan01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.2 Enzymes altering nucleic acid conformation
5.6.2.1 DNA topoisomerase
138415014 (TOP3A)
DNA replication proteins [BR:
ocan03032
]
Eukaryotic type
DNA Topoisomerases
138415014 (TOP3A)
DNA repair and recombination proteins [BR:
ocan03400
]
Eukaryotic type
DSBR (double strand breaks repair)
HR (homologous recombination)
Bloom's syndrome complex (BTR)
138415014 (TOP3A)
FA (Fanconi anemia) pathway
138415014 (TOP3A)
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Topoisom_bac
Zn_ribbon_GRF
Zn_ribbon_Top1
Toprim
zf-C2H2_10
Zn_ribbon_GRF_2
Zn_ribbon_recom
Motif
Other DBs
NCBI-GeneID:
138415014
NCBI-ProteinID:
XP_069399071
LinkDB
All DBs
Position
11:42780341..42801266
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AA seq
919 aa
AA seq
DB search
MVMTSVSGHLLAHDFRMQFRKWQSCNPLVLFEAEIEKYCPENFVDIKKTLEREARQCQAL
VIWTDCDREGENIGFEVIHVCKAVKPSLQVLRARFSEITARAVRTACENLTEPDQRVSDA
VDVRQELDLRIGAAFTRFQTLRLQKIFPEVLAEQLISYGSCQFPTLGFVVERFKAIQAFV
PEVFHKIRVTHDHRDGVVEFSWKRHRLFNHTACLVLYQLCMEDPRATVVEVRSKAKSKWR
PQALDTVELEKLASRKLRINAKETMRIAEKLYTQGYISYPRTETNIFPKDLDLAALVEQQ
IPDPRWGAFARNILERGGPTPRNGNKSDQAHPPIHPTKYTDSLQGDEQRLYELIVRHFLA
CCSQDAQGQETTVEIDIAQERFVAHGLMILARNYLDVYPYDRWSDKTLPVYKEGTYFQPS
TVEMVDGETSPPQLLTEADLIALMEKHGIGTDATHAEHIETIKARMYVGLTPDKRFLPGH
LGMGLVEGYDSMGYEMSKPDLRAELEADLKLICEGKKDKLVVLHQQVQKYKQVFIEAVAK
ARKLDEALSQYFGAAAEVAPQEALPAVSEPIRKCPQCGRDMVLKTRKSGGFYLSCTGFPE
CRSAVWFPDSVLEASRDASVCPVCQPRPVYRLKFKFKRGSLPPTMPLEFVGCIGGCDETL
REILALRFSQGAPRVGQPASQTSSYLQASQSLNRMDSGQQGQPRPPVTRPSKALTRTLPP
PAVESESNSVTCNCGREALLLTVRKEGPNQGRQFYKCSGGGCSFFLWADSGHPGAGPPSS
ASRPPGGPLGRPPGSGTLLGGSSRSGSAGSAGTSCLCGQPAVTRTVQKEGPNQGRQFHTC
AQPREQQCGFFQWVDENVAPGTFGGPLWPGSKGGTQGLEARSKRARANSSDTGSAAKKPR
KCSLCHQPGHTRPFCPQNR
NT seq
2760 nt
NT seq
+upstream
nt +downstream
nt
atggtaatgacctcagtctcaggacacttgctggcccatgatttccggatgcagtttcgc
aaatggcagagctgcaatcctcttgtcctctttgaagcagaaattgaaaagtactgccca
gagaattttgtagacatcaagaaaactctggagcgagaggcccggcagtgccaggccctg
gtgatctggaccgactgtgacagagagggtgaaaacattgggtttgaggtcatccacgtg
tgcaaggctgtgaagcccagcctgcaggtgctgcgagcccgtttctctgagatcactgcc
cgcgccgtccggacagcatgtgaaaacctcacggagcccgaccagagagtgagcgacgcc
gtggatgtgaggcaggagttggacctgcggatcggggcggccttcaccaggttccaaacg
ctgcggctgcagaagatcttccccgaggtgctggcggagcagcttatcagctacggcagc
tgccagttccccaccctggggttcgtggtggagaggttcaaagccattcaggcgtttgtg
ccagaagtcttccacaagatccgagtgactcatgaccacagggacggcgtggtggagttc
agctggaagaggcatcgtctcttcaaccacacggcgtgtctcgtcctctaccagctatgc
atggaggatcccagggcgacggtggtagaggtcaggtccaaagccaagagcaagtggagg
cctcaagctttggacactgtggagctggagaagctggcgtctcggaagttgaggataaat
gctaaagaaaccatgaggattgcagaaaagctctatacccaagggtacatcagctatcct
cgaactgaaacgaacattttccccaaagacctagacctggcggcactggtggagcagcag
atcccggatccacgctggggggcctttgctcgaaacattctagagcgcggtggccccacc
ccacgcaatggaaataagtctgaccaagcgcaccctcccatccaccccaccaaatacact
gacagcctgcagggggatgaacagcgactgtacgagctcatcgtccgccacttcctggcc
tgctgctcccaggatgcccagggccaggagaccactgtggagatcgacatcgcgcaggag
cgcttcgtggcccatggcctcatgatcctggcccggaactatctggatgtgtacccgtat
gatcgctggagtgacaagaccctccctgtctacaaggaaggcacctactttcagcccagc
actgtggagatggtggatggggagaccagtcccccccagctgctcaccgaggctgacctc
attgccctcatggagaagcacggcattggtacggatgccacgcacgccgagcacattgag
accatcaaggcccggatgtatgttgggcttacaccagacaagcgctttctccctgggcac
ctgggcatggggctcgtggaaggctatgactccatgggctacgagatgtccaagcctgac
ctgcgggccgagctggaggctgacctgaagctcatctgcgaggggaagaaggacaagctg
gtggtcctgcatcagcaggtgcagaagtacaagcaggtgttcatcgaagccgtggccaaa
gccaggaagttggacgaggccttgtcccagtacttcggggcagctgcagaggtggcccca
caggaagccctgccggctgtgtccgagcccatcaggaagtgtccgcagtgcggccgggac
atggttctcaagaccaggaagagtggcgggttttacctcagttgcacgggcttccctgag
tgtcggtcggctgtctggttcccagacagtgtgctggaggccagcagggatgcgagcgtg
tgcccagtgtgtcagccacgccccgtttacagattgaagttcaagtttaaacgaggcagc
ctgcccccaaccatgcccctggaatttgtcggctgcatcggcgggtgtgacgagaccctg
agggagatcctggccctcagattctcacagggcgccccccgagtcggccagcccgccagc
cagacctccagctacctgcaggctagccagtccctgaacagaatggacagtggccagcag
ggccagccccggccccctgtcaccaggccctcgaaggctttgaccaggacgctgccccca
cccgccgttgagagcgagagcaactcggtgacctgcaactgtggccgggaggccctgctg
ctcaccgtccggaaggaggggcccaaccaaggccgccagttctacaagtgcagcggcggg
ggctgcagcttctttctgtgggctgacagcggccacccgggagccgggcctccctcctca
gcgtccagacctccaggcggccccctgggacgcccaccgggctccgggactctcctgggc
gggtccagcaggtccggcagcgctggcagcgctggcacgtcctgcctgtgtggccagccg
gctgtcacacgcaccgtgcagaaggaggggcccaaccagggccgccagttccacacatgt
gcccagccccgtgagcagcagtgcggcttcttccagtgggtggatgagaacgtggcccca
gggaccttcggaggccccctctggccaggaagcaagggaggaacccaggggctggaggcc
agaagcaaaagggctcgggccaactcctcagacacggggtctgcagccaagaaaccccgg
aagtgcagcctttgccaccagcctggacatacccgtcccttctgtcctcagaacagatga
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