KEGG   Ovis canadensis (bighorn sheep): 138415360
Entry
138415360         CDS       T11679                                 
Symbol
SOCS3
Name
(RefSeq) suppressor of cytokine signaling 3
  KO
K04696  suppressor of cytokine signaling 3
Organism
ocan  Ovis canadensis (bighorn sheep)
Pathway
ocan04120  Ubiquitin mediated proteolysis
ocan04380  Osteoclast differentiation
ocan04630  JAK-STAT signaling pathway
ocan04668  TNF signaling pathway
ocan04910  Insulin signaling pathway
ocan04917  Prolactin signaling pathway
ocan04920  Adipocytokine signaling pathway
ocan04930  Type II diabetes mellitus
ocan04931  Insulin resistance
ocan04932  Non-alcoholic fatty liver disease
ocan04935  Growth hormone synthesis, secretion and action
ocan05160  Hepatitis C
ocan05164  Influenza A
ocan05168  Herpes simplex virus 1 infection
Brite
KEGG Orthology (KO) [BR:ocan00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04120 Ubiquitin mediated proteolysis
    138415360 (SOCS3)
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    138415360 (SOCS3)
   04668 TNF signaling pathway
    138415360 (SOCS3)
 09150 Organismal Systems
  09152 Endocrine system
   04910 Insulin signaling pathway
    138415360 (SOCS3)
   04920 Adipocytokine signaling pathway
    138415360 (SOCS3)
   04917 Prolactin signaling pathway
    138415360 (SOCS3)
   04935 Growth hormone synthesis, secretion and action
    138415360 (SOCS3)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    138415360 (SOCS3)
 09160 Human Diseases
  09172 Infectious disease: viral
   05160 Hepatitis C
    138415360 (SOCS3)
   05164 Influenza A
    138415360 (SOCS3)
   05168 Herpes simplex virus 1 infection
    138415360 (SOCS3)
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    138415360 (SOCS3)
   04932 Non-alcoholic fatty liver disease
    138415360 (SOCS3)
   04931 Insulin resistance
    138415360 (SOCS3)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04121 Ubiquitin system [BR:ocan04121]
    138415360 (SOCS3)
Ubiquitin system [BR:ocan04121]
 Ubiquitin ligases (E3)
  Multi subunit type E3
   Cul5 complex
    Target recognizing subunit
     138415360 (SOCS3)
SSDB
Motif
Pfam: SH2 SOCS_box
Other DBs
NCBI-GeneID: 138415360
NCBI-ProteinID: XP_069399986
LinkDB
Position
11:61865388..61868943
AA seq 229 aa
MVTHSKFPAAGMSRPLDASLRLKTFSSKSEYQLVVNAVRKLQESGFYWSTVTGGEANLLL
SAEPAGTFLIRDSSDQRHFFTLSVKTQSGTKNLRIQCEGGSFSLQSDPRSTQPVPRFDCV
LKLVHHYMPAAGAPSFSPPPAEPSSSPSSEVPEQPPAQPLPGSPPRRAYYIYSGGEKIPL
VLSRPLSSNVATLQHLCRKTVNGHLDSYEKVTQLPGPIREFLDQYDAPL
NT seq 690 nt   +upstreamnt  +downstreamnt
atggtcacccacagcaagttccccgccgccgggatgagccgccccctggacgccagcctg
cgcctcaagaccttcagctccaagagcgagtaccagctggtggtgaacgcagtgcgcaag
ctgcaggagagcggcttttactggagcaccgtgacgggcggcgaagcgaacttgctgctg
agcgccgagcccgcggggaccttcctcatccgcgacagctcggaccagcgccacttcttc
accctcagcgtcaagacccagtcggggaccaagaacctgcgcatccagtgcgaggggggc
agcttctctctgcagagcgacccccggagcacgcagcccgtgccccgcttcgactgcgtg
ctcaagctggtgcatcactacatgcccgccgccggcgccccctcgttctccccgcccccc
gctgaaccctcctcctcgccctcctccgaggtgcccgagcagccaccggcccagccgctc
cccgggagcccccccaggagagcctattacatttactcggggggcgagaagatccctctg
gtgttgagccggcccctctcctccaacgtggccactctccaacatctctgtcggaagacc
gtcaacggccacctggactcctacgagaaagtcacgcagctgcctgggcccattcgggag
ttcctggaccagtacgatgccccgctttag

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