Ovis canadensis (bighorn sheep): 138416691 Help Entry 138416691         CDS       T11679                                  Symbol HMCN1 Name (RefSeq) hemicentin-1   KO K17341   hemicentin Organism ocan  Ovis canadensis (bighorn sheep) Brite KEGG Orthology (KO) [BR:ocan00001]  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04990 Domain-containing proteins not elsewhere classified [BR:ocan04990]     138416691 (HMCN1) Domain-containing proteins not elsewhere classified [BR:ocan04990]  EGF-like domain-containing proteins   hEGF / cEGF domain-containing proteins    138416691 (HMCN1) SSDB OrthologParalogGFIT Motif Pfam:  I-set Ig_3 Ig_2 ig Ig_VEGFR-1-like_5th V-set C2-set_2 VEGFR1-3_N_Ig-like Ig_5 Ig_SEMA-3_4_7A TSP_1 EGF_CA VWA_4 G2F V-set_CD47 cEGF TSP1_spondin Receptor_2B4 GBD_Hemicentin FXa_inhibition TSP1_CFP_C EGF_3 TSP1_ADAMTS EGF Fibulin_C hEGF Motif Other DBs NCBI-GeneID:  138416691 NCBI-ProteinID:  XP_069402398 LinkDB All DBs Position 12:77567911..78111628 Genome browser AA seq 5635 aa AA seqDB search MISWDMIHTIFLLALLYPSRAQDAVPQLEVEAEEIPEGASTLAFVFDVTGSMYDDLVQVI EGASKILETSLKRPKRPLFNFALVPFHDPEIGPVTVTTDPKKFQYELRELYVQGGGDCPE MSIGAIKIALEISLPGSFIYVFTDARSKDYRLTHEVLQLIQQKQSQVVFVLTGDCDDRSH IGYRVYEEIASTSSGQVFHLDKKQVNEVLKWVEEAVQASKVHLLSTDHLEQAVNTWKIPF DPSLKEVTVSLSGPSPMIEIRNPLGKLIKKGFGLNELLNIHNSAKVVNVKEPEAGIWTVK TSSTGRHSVRITGLSTIDFRAGFSRKPTLDFKKTVSRPVQGIPTYVLLNTSGISIPARVD RLELLSISGSSLKTIPVKYYPDRKPYGIWNISDFIPPNEAFFLKVTGYDKDDFPFQRVSS VSFSSIVPDAPKVTMPEKTPGYYLQPGQIPCAIDSLLPFTLSFVRNGVTLGVDQYLKESA RVTWDIEEVTLSDEGPYECIAVSSAGTGRAQTFFDVSEPPPVIQVPNNVTVTPGETAVLT CLVVSAVGYNLTWQRNGRDVRLTAPAGMRILANLSLELRSVKFSDAGEYRCVVSNEGGSS TEAVFLTVQEPPKVTVMPKNQSFTGGSEVSIMCSVTGYPKPKISWTMNDMFIMGSHRYRM TSEGNLFIKNAVPKDAGIYGCLASNSAGMDKQTSTLRYIEAPKLIVVQSELLVALGDTTV MECKTSGVPPPQVKWFKGDLELKPSTFLIIDPLLGLLKIQETQDLDAGDYTCVAVNDAGR ATGRITLDVGSPPVFIQEPTDVSVEIGSNVTLPCYVQGYPEPKIKWRRLDNIPIFSRPFS VSSISQLRTGDLFISNLWASDKGTYICEAENQFGKIQSQTTVTVTGLVAPLIGISPPVTS VIEGQQLTLPCALLAGNPIPERRWIKNSAMLVQNPYITVRSDGSLHIERVRLQDGGEYTC VASNVAGTTNKTTTVDVHVLPTIQHGQQILSTIEGIPVTLPCKASGIPKPSIAWSKKGEL ISTSSAKFSAGADGSLYVVSPRGEESGEYVCTATNAAGYAKRKVQLTVYVRPRVFGDQRG PSQDKPVEISVLAGEEVTLPCEVKSLPPPVITWAKETQLISPFSPRHTFLPSGSMKITET RVSDSGMYLCVATNIAGNVTQSVKLNVHVPPKIQRGPKVMKVQVGQRVDIPCSAQGTPLP VITWFKGGSAVLVDGLQHISHPDGTLSIKQAMLSDAGIYTCVATNIAGSDETEITLHVQE PPILEDLEPPYNTAFQERVANQRIAFPCPAKGTPKPTIKWLRNGRELTGQELGISILEDG TLLVIASVTPYDNGEYICVAVNEAGTTERRYNLKVHVPPVIKDKEQVINVSVLVNQPTSL FCEVEGTPSPIVMWYKDDVQVTESSSIQIINNGKILKLFRASPEDAGRYSCKAVNVAGAS QKHFNIDVLVPPTIIGAGSPGEVSVVLNQDTTLECQVKGTPFPVIHWFKDGKPLFLEDPN IEILDRGQVLHLKNARRSDKGRYQCTVSNAAGKQAKDIKLTIYIPPSIKGGNVTTEVSAL INSVIKLECETRGLPMPAITWYKDGQPVISSSQALYVEKGQFLHIPRAQVTDSAAYKCLI TNVAGSAEKSFHVDVYVPPMIEGDLAAPLNKQVIVAHSLTLECKAAGNPPPVLTWLKDGV PVKVSDNIRIEAGGKKLEITSALEVDRGQYICVATSVAGEKEIKYEVDVLVPPAIEGGDE TSYFIVMVNNLLELDCQVTGSPPPTIMWLKDGQLIDERDGFKILLNGRKLVIAQAQVSDT GLYRCVATNTAGDHKKEFEVTVHVPPTIKSSGLSERAVLKYKPIALQCIANGIPNPSITW LKDGQPVNTAQGNLKIQSSGRLLQIAKALMEDAGRYTCVATNAAGETQQLIQLHVHEPPS LEDAGKMLNETVVVNSPVQLECKAAGTPTPAITWYKDNRPLSDSSSVTFLNRGQIINIES AQITDAGIYKCVAINSAGATELLYSLQVHVPPSIFGSNDMVAVVVNNLVRLECEARGIPA PSLTWLKDGSPVASFVNGIQILSGGRILALTSAQISDTGRYTCVAINAAGEKQRDIDLRV YVAPNIMGEEQNVSVLISQAVELLCRSDAIPPPTLTWLKDGRPLLKKPGLSVTENGSVLK IEDAQVQDSGRYTCEATNVAGKTEKNYNVNIWVPPKISGSDEVAQLTVIEGHLISLLCES SGIPPPNLLWKKKGSAVLADSAGRVRILSGGRQLQISIAEKSDAGLYSCMASNVAGTAKK DYSLQVYTRPTISNSGSHPTEVIVTRGKSVSLECEVEGIPQPAVTWMKDGRPLTKGRGME IMGEGRGVQLKNVHVSDTGRYVCVAMNIAGMTDRKYDLSVHTPPSIIGNHRTPENISVVE KSSVSLNCEASGIPLPSITWLKDGWPVNLSSSLRILSGGRILRLIRTRTEDAGQYTCVVR NAAGEERKIFRLSILVPPRIMGETAFEDVKVKEKQSVTLTCEVTGNPVPEITWHKDGQLL KEDDTHHLMSGGRFLQIVNAQVSHTGRYTCLASNTAGDKSKSFSLNVLVSPIIAGVDGDG NPEDVTVILNSPTSLVCEAYSYPPATITWFKNGTPLESNRNIRILPGGRTLQILNAQEDD AGRYACVATNEAGEMIKHYEVKVYIPPIINKGDLLGPGLSPREVKIKVNNTLTLECEAYA IPSASLSWYKDGQPLKSDDHVTIAASGHTLQIKETQISDTGRYTCVASNVAGEDELDFDV NIQVPPSFQKLWEIGNMVDTGRRGEAKDVIINNPISLYCETNAAPAPTLTWYKDGHPLTS SERVLILPGGRVLQIPRAKVEDAGRYVCVAVNEAGEDSLQYDVRVLLPPVIKGANGDLPE EVTVLVNKSVLMECLFSGSPTPRSSWQKDGQPLLEDERHKFLSNGRILQVLNSQITDIGR YVCIAENTAGSAKKYFNLNVHVPPSIIGPNPENLTVVVNNFISLTCEVSGFPPPDLSWLK NEQPIKLNTNALIVPGGRTLQIIRAKVSDGGEYTCIAINQAGESKKKVSLTVYVPPSIKD HGSESLSVVNVREGTSVSLECESNAVPPPVITWYKNGRMLTDSAPLAILADGQMLHIAKA EVSDTGQYVCRAINVAGRDDKNFHLNVYVPPSIEGPENEVTVETVSNPVTLTCDATGLPP PSIAWLKNHKPIENSGSLEVHILSGGSKLQIARSQHSDSGNYTCIASNMEGKAQKNYILS IQVPPNVADAEIPSEVSVLLGENVELVCNANGIPTPLIQWLKDGKPIVNSETERIRVTAD GSTLNIYGALPSDKGKYTCVATNPAGEEDRIFNLNVYVPPAIRGNKEEAEKLMALVDTSI NIECRATGMPPPQINWLKNGLPLPLSSHIRLLSGGQVIRIVRAQASDVAVYTCVASNRAG VDNKHYSLQVLVPPSLHSGMGTEEITIVKGSSTSMTCFTDGTPAPRMSWLRDGHPLGLDA HLSISSQGMVLQLIKAETEDSGRYTCIASNEAGEVSKHFILKVLQPPHINGSEEPIEMSV IVNNPLELTCMASGIPAPKITWMKDGRPLPQMDQMQTLGGGEVLRISSTQVEDTGRYTCL ASSPAGDDDKEYLVRVHVPPNIAGTGEPQDFTVLRNRQVTLECKSDAVPPPVITWLKNGE RLQATPRIRILSGGRYLQINNADLGDTANYTCVASNIVGKTTREFILTVNVPPSIKSGPQ SLVIHLNKSTLLECFAEGVPAPKITWRKDGAVLSGSHARYSILENGFLHIQSAQVTDSGR YLCMATNAAGTDRRRIDLQVHVPPSIAPGPTNITATVNVQTTLACEATGIPKPSINWRKN GHLLNVDQNQNSYRLLSSGSLVIISPSVDDTATYECTVTSDAGEDERTVDLTVQVPPSIA DEPTDFLVTKHTPAVITCTASGVPFPSIHWMKNGIRLLPRGEGYRILSSGAIEILATQLS HAGRYTCVARNSAGSAHRHVSLHVQEAPVIQPQPSELDVILNNPILLPCEATGTPSPFIT WQKEGINVISSGRSHAVLPHGGLQISRAVREDAGTYMCVAQNPAGTALGKIKLNVQVPPV ITPHPKEYVTVVDKPIMLPCEADGLPPPDIMWHKDGHVIMESVRQRILSSGALQIAFAQP GDAGQYTCMAANVAGSSSTSTKLTVHVPPRIQSTEVHYTVNENSQAVLPCVADGIPTPAI NWKKDNVLLANLLGKYTVEPYGELLLENVVPEDSGTYTCIANNAAGEDTHTISLTVHVLP TFTELPGDVSLNKGEQLRLNCKATGIPLPKLTWTFNNNIIPAHFDSVSGHSELVIERISK EDSGTYVCTAENSVGFVKAIGFVYVKEPPVFKGDYPSNWIEPLGGNAILNCEVKGDPAPT IQWSRRGIDIEISHRIRQLGNGSLAIYGTVNEDAGDYTCVATNEAGVVERSMSLTLQSPP IITLEPVETIINAGSKVILNCQATGEPRPTITWSRQGHSILWDERINVLSNNSLHIAAAQ KEDTSEYECVARNLMGSVLVRVPVIVQVPGGFSQWSAWRPCSVTCGKGIQKRSRLCNNPS PANGGKPCQGSDSEIQNCHHKPCPVDGNWSEWSLWEECTRSCGRGNRTRTRTCNNPSAQH GGRPCDGIAVETIMCNIRPCPVHGAWSTWQPWGTCSVSCGKGTQTRTRLCNNPPPSFAGS YCDGAETQMQVCNERHCPIDGKWATWTSWSACSVSCGGGARQRTRDCSDPAPQYGGNKCE GSDVQSDFCNSDSCPTHGNWSPWSGWGICSRTCNGGQMRRYRTCDNPHPSNGGRACGGPD SQIQRCNTDMCPVDGSWGNWHSWSWCSTSCGGGEKTRKRLCNNPIPSKSGRPCPGDATQV SRCNIQVCPGGPQRARGSVIGSINDVEFGIAFLNATVTDSPNSDTRIIHAKITNVPRSLG PAMRKIVSILNPIYWTTAKEIGEAVNGFTLTNAVFKRETQVEFATGEILRMTHVARGLDS DGALLVDIIVSGHVLQLQSPAEVTVKDYTEDYVQTGAGQLYAYSTRLFTIDGISVPYTWN HTVFYDEAQGRMPFLVETLHASSVESDYNQLEETLGFKIHAAISKGERSNQCPSGFALDS VGPFCADEDECATGNPCSHFCHNAMGTYYCSCPKGLTIAADGRTCQDIDECALGGYTCHA GQDCDNTIGSYRCVVRCGIGFRRTSDGLSCQDINECQESSPCHHRCFNAIGSFHCGCEPG YQLKGRKCVDINECRQNVCRPDQHCKNTRGGYKCIDLCPNGMTKAENGTCIDVDECKDGT HQCRYNQICENTRGSYRCVCPRGYRSQGLGRPCLDINECEQVSKPCAYQCFNTPGSFKCI CPPGQHLLGDGKSCAGLERLPNYGTQYNSYNLARFSPMRNNYQPQQHYRQYSHLYSSYSE YRNSRTSLSRTRRTIRKTCPEGSEASLDTCVDINECENTDTCQHECKNTFGSYRCICPPG YQLMINGKTCQDIDECLEQNVRCGPNRMCFNMRGSYRCIETPCPPDYQRDPVSGFCLKNC PPNDLECALSPYALEYKLVSLPFGIAANQDLIRLVAYTQDGVMHPRTTFLMIDEEQTIPF ALRDENLKGVVYTIRPLQEPETYRMRVRALSYSANGTVEYQTTFIVYIAVSAYPY NT seq 16908 nt NT seq  +upstreamnt  +downstreamnt atgatttcctgggacatgatccacaccatattcctgctcgctcttctttatccttcccga gcgcaggatgcagtcccccagttggaggtcgaggcagaagaaattcccgagggggcctcc accttggcttttgtgtttgatgtgactggttccatgtatgatgatctagttcaggtgatc gagggggcttccaaaattttggagacgtctttgaaaagacctaagagacctcttttcaac tttgctttggtgcctttccacgacccagaaattggcccagtaacagttaccacagatccc aagaaatttcaatatgagctcagagaactctatgttcagggtggtggcgactgtccagaa atgagtatcggagctataaaaattgccttggaaatttcccttcctgggtctttcatctat gttttcactgatgcgcgatccaaggattatcgactcactcatgaggtgctgcagcttatc caacagaaacagtcacaggtggtatttgtgcttactggagattgtgatgacagaagccat attggatacagagtctatgaagaaattgcctctacaagttctggtcaagtgttccatctc gacaaaaaacaagtgaatgaggttttaaaatgggtggaagaagcagtgcaggcttccaaa gttcacctcttatcaacagatcatttggaacaggctgtaaatacttggaaaattcccttt gatccaagtctaaaagaggttactgtgtctctgagtggcccttctccaatgattgaaatt cgtaatcctttaggaaagctgataaaaaagggatttggcctgaatgagctattaaatatt cataactctgccaaggtggtgaatgttaaagagccagaggctggaatatggacagtgaag acgtctagcactggaaggcactctgttcgcattactggcctcagtactattgactttcga gctggtttttcccgaaagcccaccctggacttcaaaaaaaccgtcagcagaccggtgcaa ggaatacctacctatgtgctgctgaatacttctggaatttccatcccagctagagtagat cgtcttgaacttctgagtatctcaggcagttctcttaagactattcctgttaaatattat cctgatagaaaaccttatggcatatggaatatttctgattttataccaccaaatgaagct ttctttctcaaagtaacaggctatgataaggatgattttcccttccagagagtgtcaagt gtttccttctctagtattgtcccagatgctccgaaagttacaatgcctgagaaaaccccg ggctactacctgcagccgggccagattccctgcgccattgacagtcttttgccttttacc ttgagttttgtcagaaatggagttacgcttggagtcgaccagtatttaaaagaatctgcc cgcgtgacgtgggatattgaggaggtcactctgtctgacgaaggcccctacgagtgcatc gctgtcagtagtgcagggactgggcgagcacagacgttcttcgacgtgtcagaacccccg ccagtcatccaagtgcctaataatgttacagtcactcctggagaaacagcagttttgacg tgccttgtcgtcagtgcagtgggttacaatctaacctggcagaggaatggccgagatgtc aggctgacagctccagcaggaatgaggatcttggctaacctttccctggagctcaggagt gtgaaattcagtgatgcaggagagtatcgctgtgttgtttccaatgaaggaggatcatca actgaggccgttttccttacagtgcaagaaccgcccaaagtcactgtgatgcccaagaat cagtccttcacaggtggatcagaggtctccatcatgtgttctgtaacaggttatcccaaa ccaaagatctcctggaccatgaatgatatgtttatcatgggttcacacaggtataggatg acctcagaaggtaacttgtttatcaaaaatgcagttcccaaagatgcagggatctatggt tgcctggcaagtaattcagctggaatggataaacagacttctaccctcagatacattgaa gccccgaagttgattgtagttcagagtgagctcttggttgccctgggggatacaacagtt atggaatgtaaaacctctggtgttcctccacctcaagttaaatggttcaaaggagatctt gagctgaagccctcaacattcctcattattgaccctctcttgggacttttgaagattcaa gaaactcaagatttggatgctggtgattatacgtgtgttgctgtcaatgatgctggaaga gcaactggcaggataactctggatgttggctcacctccagtttttatacaagaacctact gatgtatctgtggagattggctcaaatgtgacattaccttgctatgtccagggttatcca gaaccaaagattaaatggcgaagactagacaacatacccatcttctcaagacctttttca gtgagttccatcagccaactaagaacaggagatctctttatttcaaacttatgggcaagc gataaagggacatatatttgtgaagcggaaaaccagtttggaaagatccagtcccagaca acagtaacagtgactggacttgtcgctccactcattggaatcagccccccagttaccagt gtaattgaaggacagcagcttactttgccttgtgctctactggctggaaatcccattcca gaacgtcggtggattaagaattcggccatgttggtccaaaacccttacatcactgtacgc agtgatgggagtctccatattgaaagagtccgcttgcaggatggaggcgagtatacttgt gtggccagtaacgttgctggaaccactaacaaaactaccactgtggacgtgcatgttctg ccaaccattcagcatggacagcagatcctcagtaccattgaaggcattccagtaacttta ccgtgcaaagcaagtggaattcccaaaccgtctattgcctggtccaagaagggcgagctg atctctaccagcagtgctaagttttccgcaggggctgatggaagtctgtacgtggtgtcc cccaggggtgaggagagtggggagtatgtgtgcaccgccaccaatgcagctggctacgcc aaaaggaaagtgcagctgactgtctatgtaaggcctagagtgttcggagaccaaagggga ccatcccaggataagcccgttgagatctcagtccttgcgggagaagaggtgacccttcca tgtgaagtgaagagtttacccccacccgtcattacctgggccaaagaaacccagctcatc tctccattctctccaagacacacgttcctcccctctggttcaatgaagatcactgagacc cgtgtttcagatagtgggatgtatctttgcgtcgctacaaatattgcagggaatgtgact cagtctgttaaattaaacgtccatgtgcctccaaagatacagcgtggccctaaagttatg aaagtccaagttggccaaagagtggacattccttgcagtgctcaagggacacctcttcct gttatcacctggttcaaaggtggaagcgccgtgctggttgatggactgcagcatattagc catccagatgggacattaagcatcaaacaagcgatgctctcagatgctggcatatataca tgtgtcgctactaacatagcaggcagtgatgagacggagataacactacacgttcaagaa ccacctattctggaagacctagagcctccatataacactgcattccaagaaagagtggcc aaccaacgcattgcatttccatgtcctgcaaaaggtacccccaaaccaaccatcaaatgg ttgcggaatggtagagagctgacaggccaagagcttggtatttctatattagaagatggc acattgttggttattgcttctgttacaccatatgacaacggggagtatatttgtgtggca gtcaatgaagctggaaccacagaaagaagatataacctcaaagtccatgttcctccagta attaaagataaagaacaagtaataaatgtgtccgtgttggtcaaccagccaaccagtctc ttttgtgaagttgaaggtactccgtcccccatcgttatgtggtataaagatgatgttcag gtgactgagagcagcagtattcagattataaacaatgggaagatattaaagctcttcaga gcctctccagaggacgcaggaagatattcctgtaaagcagttaatgttgcaggcgcttct caaaagcattttaacattgatgtgctagtcccgcccaccataataggtgctggttcccct ggtgaagtctcagttgtcctgaaccaggataccacacttgaatgccaggtgaaaggcacc ccctttcccgttattcactggttcaaagatggcaagcctttatttttggaggaccctaat attgaaattctagacagaggacaagttttacatttaaagaatgcacgaagaagtgacaag ggacgctaccagtgtactgtgtctaatgcagctggcaaacaagccaaggatataaaactg acaatctatattccacctagtattaaaggagggaatgtcaccacagaagtgtcagctttg atcaacagcgtaattaaactggaatgtgagacacgaggacttccaatgcctgctattact tggtataaggatggccagccagtcatatccagctcacaagcactttatgttgaaaaggga caatttcttcatattcctcgagcacaggtcactgattcagcggcatataagtgtctaata accaatgttgctggaagtgctgaaaaatcattccatgtggacgtctatgttcctccaatg attgaaggtgacctggctgcacctctgaataagcaagtgatagttgctcattcactgacc ctggagtgtaaagctgctggcaaccctcctccagttctaacctggttgaaagacggtgta cctgtgaaagtcagtgacaacatccgcatagaagctggtgggaaaaaactagaaattaca agtgccctagaagtcgacaggggacagtatatatgtgtggctacgagtgtggcaggagaa aaggaaatcaaatacgaagttgatgtcttagtgccaccagctatagaaggaggagatgaa acgtcttacttcattgtaatggtcaataacttgctggaactagattgtcaagtgacaggt tctcctccaccaactatcatgtggctgaaggacggccagctcattgatgaaagagatgga ttcaagatcttactaaatggacgcaaactggttattgcccaggctcaagtatcagacaca ggcctttatcggtgtgtagcaacaaacactgctggagaccacaagaaggaatttgaagta actgttcatgtgcctccaacaatcaaatcctcaggtctttctgagagagctgtgttgaag tacaagcccatcgccttgcagtgcatagctaatggcattccgaatccatccatcacatgg ttgaaagatggacagcctgtcaacactgcccaaggaaacctcaaaatacagtcttctggt cgacttctacaaattgccaaagccctgatggaagatgctggcagatacacgtgtgtggcc accaatgcagctggagaaacacagcagctcattcaactgcatgtacatgaaccacccagc ctggaggatgcagggaagatgctgaatgagaccgtggtggtgaacagccctgtacagctg gagtgtaaggcagctggaactcccacgcctgctattacatggtacaaagataatcgtcca ctatcagattccagtagtgtgactttcctgaacagaggacagatcatcaatattgaaagt gcgcagatcacagatgctggcatatataaatgtgtggccatcaactcagctggagcaacc gagttattgtacagtctgcaggtccatgtgcccccgtcaatttttggtagcaatgacatg gtggcagttgtggttaataacctggtgaggttagagtgtgaagccagaggcatcccagcc ccaagtctgacctggctgaaagatgggagccctgtcgctagcttcgttaatgggatacag attctgtctgggggccgcatcctagcattgaccagtgcacagatcagtgataccgggcga tacacctgtgtggcaataaatgctgccggggagaaacaaagggacattgacctcagagta tatgttgcaccaaatattatgggagaagaacagaacgtctctgtcctcattagccaagct gtggagttgctatgtcgaagtgatgctattcccccaccgactctgacctggttaaaagat ggccgccccttgttgaagaagccaggtctcagtgttactgaaaatgggagtgtgctaaag attgaagatgctcaggttcaagatagtggtcgctacacttgtgaagccacaaatgttgca ggaaaaactgagaagaactataatgtcaacatttgggtaccaccaaaaatttctggttct gatgaagttgctcagcttacagtcattgaaggacacctcattagtctattgtgtgaatca agtggtattcctcccccaaatctcctttggaagaagaaaggctccgcagtgctggctgat tctgcagggcgagtcagaattttatctggaggcaggcagttgcagatttcaattgcagaa aaatctgatgcagggctctattcatgtatggcatcgaatgttgctgggactgcaaagaaa gactacagtctgcaagtttacactcgaccaactatatccaacagtggtagccaccctact gaagtcattgtaactcgaggaaagagcgtttccttggagtgtgaggtggaaggtattcct cagccagcagtgacctggatgaaagatggccgccccttgacaaagggaagaggaatggaa ataatgggtgaaggtcgtggtgtgcagctgaagaacgttcatgtgtcggacacaggccgt tatgtgtgtgttgctatgaatatagcaggaatgactgacagaaaatatgacttaagtgta cacacccctccaagcatcattggaaaccacaggacacctgaaaatataagtgtggtggaa aaaagctcagtgtccctaaattgtgaagcttcaggaattcccctgccttcaattacgtgg cttaaagatgggtggcccgtcaaccttagcagttccctgcgaatcctctcaggaggtagg attctgcgattgatacggaccagaacagaagatgctggccagtatacatgtgttgtaaga aatgcagctggcgaagaaagaaaaatctttcggctttcaatattagtaccacctcgcatc atgggtgaaactgcatttgaagatgtgaaagtaaaagagaaacagagtgttacactgact tgtgaagtgacagggaatccagtaccagaaataacatggcataaagatggccagctcctg aaagaagatgacactcatcatcttatgtctggtggccgttttcttcagattgtgaatgcc caagtgtcacacactgggagatacacatgtttggcatctaatacagctggtgacaagagc aaaagtttcagtcttaatgtgttggtatctcctataattgctggtgttgatggcgatggc aaccctgaagacgtcactgttatccttaacagccccacgtctttagtctgcgaagcttat tcatatcccccagccaccatcacctggtttaagaatggaactcctttagaatccaaccga aatatccgtattcttccaggaggcaggactctgcagatcctaaatgcacaggaggacgat gctgggagatacgcttgtgtagccactaatgaggcaggggagatgataaagcattatgaa gtgaaggtctacattccacccataatcaataaaggagacctcttggggccaggtctttcc cctagagaagtgaagatcaaggtaaacaacacgctgaccttggagtgtgaagcctatgcg attccttctgcatccctcagctggtacaaggatggacagccccttaaatcagatgatcat gttactattgctgccagtggacacacacttcaaatcaaggagactcaaatatcagacact ggacgatacacgtgtgtagcatctaatgttgcaggtgaagatgagctggattttgatgtg aatatacaagttcctccaagttttcagaagctctgggaaataggaaacatggtggacact ggcaggagaggtgaagccaaggacgtgatcatcaacaatcccatctctctctattgtgag actaacgctgcccctgctcctacactgacatggtataaagatggccaccctctgacctca agtgagagagtactgattttgccaggagggcgagtgttacaaattcctcgggctaaagta gaagatgctgggagatacgtgtgtgtggctgtgaatgaggctggagaagattcccttcag tatgatgtccgtgtactcttgccgccagttatcaagggagcaaatggtgatctccctgaa gaggtcaccgtgctggtgaacaagagtgtgctgatggagtgtttattcagtggcagtccc acaccaaggagttcctggcaaaaagatgggcagcccttgctagaagatgagcgtcataaa tttctatctaatgggagaattctacaggttctaaatagtcaaataacagatatcggcaga tatgtgtgcattgctgagaacacagctggaagtgccaaaaaatattttaacctcaatgtt catgttcctccaagtatcattggtcctaaccctgaaaatctcactgttgtggtgaacaat ttcatctctttgacctgtgaggtctctggttttccacctcctgatctcagctggctcaag aatgaacagcctatcaaactaaacacaaatgctctcattgtgcctggtggtcgaactttg caaattatccgggccaaggtatctgatggtggtgaatacacttgtatagctatcaaccaa gctggggaaagcaagaaaaaagtttccctgactgtttatgtgcccccaagcattaaagat catggaagcgaatctctttctgtagttaatgtaagagaggggacctcagtatcactggag tgtgaatcgaatgctgtcccgcctccagtcatcacctggtataagaatggacggatgcta acagactctgctcccctggcgattttggccgatggacaaatgctgcacatcgcaaaagct gaggtatctgacacaggccagtatgtatgtagagctataaatgtagcaggacgggatgat aaaaatttccacctcaatgtatatgtgccacccagtattgaagggcctgaaaacgaagtc actgtggagacagtcagcaatcctgttactttaacatgtgatgctactggactcccacct ccctccatagcatggttgaagaaccacaaacccatagaaaattctggctcactggaagtt catattttgtctgggggaagcaaactccaaattgccaggtcccaacattcagatagtgga aactatacatgcattgcctcaaatatggagggaaaagcacagaaaaattacattctttca attcaagttcctccaaatgttgctgatgctgagattccaagtgaagtcagtgtccttctt ggggaaaatgttgagctggtctgcaatgcaaatggcattcccaccccacttattcagtgg cttaaagatggaaagcccatagttaacagtgaaacagaaagaattcgggtgactgcagac ggcagcacattaaacatttacggagctctcccatccgacaaggggaagtacacgtgtgtt gctactaatcctgctggagaagaagaccggatttttaatttaaatgtctatgttccacct gcaattaggggtaataaagaagaagcagagaaattaatggctttggtggacacctcaata aatattgaatgcagagccacaggaatgcctccaccacagataaactggcttaagaatgga cttcctctgcctctctcctcccatatccggttgctctctggaggacaagttatcaggatt gtgagagctcaggcatccgatgttgctgtgtatacttgtgtggcatccaacagagctggg gtggataataaacattacagtcttcaagttttggtaccaccaagtctgcacagtgggatg gggacagaggaaatcacaattgtcaagggtagttccacctccatgacatgttttactgat ggaaccccagctcccaggatgtcctggcttagagatggtcaccctctggggctagatgcc catctgtcaatcagctctcaaggaatggtccttcagctcatcaaagcagaaactgaagat tcgggacggtacacctgcattgcctcaaacgaagcaggagaagtcagcaaacactttatc ctgaaggtcttgcaaccacctcatatcaatggatctgaagaacccatagagatgtcagta attgttaataatcctcttgaacttacctgcatggcttctggaatcccagctcctaagatt acctggatgaaagatggtcgaccccttccacagatggatcagatgcagactcttggagga ggagaggttcttcgaatatctagtactcaggtggaagatacaggaagatacacatgtctg gcatccagtcctgcaggagatgatgataaagagtatttagtgagagtgcatgtaccccct aatattgctggaactggtgagccccaggatttcactgtgttacggaacagacaagtgaca ttggaatgcaaatcagatgcagtgcctccacctgtaatcacttggcttaaaaatggagaa cggttacaggcaacacctcgaataagaatcctatctggagggagatacttgcaaattaat aatgcagatctaggtgataccgccaattatacctgtgttgccagcaacattgtgggaaag actacaagagagtttattctcactgtcaatgttcctccaagcataaagagtggcccccag agtcttgtcattcacttaaataagtcaactctattggaatgctttgcagaaggtgtgcca gccccaaagataacatggagaaaggatggagctgttctatctgggagtcatgcaagatac tccatcttggaaaatggattccttcatatccagtcggcacaagtgactgatagtgggcga tatttgtgtatggctaccaatgctgctgggacagatcgcaggcgaatagatttacaggtc catgttcctccatccattgctccgggtcctaccaacataactgcaacagtaaatgttcaa accactctggcttgtgaggctactggtataccaaaaccgtcaatcaactggagaaaaaac gggcatcttctgaatgtggaccaaaatcagaattcatacaggctcctttcttcaggttcg ctggtaattatttccccttctgtggatgacactgcgacctatgagtgcacggtgaccagt gatgccggagaggacgagagaactgtggatctcactgtccaagttccaccttccattgct gatgagcctacagacttcctagtaaccaaacacacacccgcagtgatcacctgcaccgct tcaggagttccgtttccctcaatccactggatgaagaatggcataagactgcttcccaga ggagagggctatagaattctgtcctcaggagcaattgaaatacttgccactcaactaagc catgctggaagatatacttgtgttgccaggaattcagctggttctgcacatcgacacgtg agccttcacgttcaagaggctccagtcattcagcctcagccaagtgagctggacgtcatt ctaaacaatcccattttattaccctgtgaagcaacagggacacccagtcctttcatcact tggcaaaaagaaggcatcaatgtcatcagttcaggtagaagccatgcagttcttccccat ggaggcttgcagatttccagagctgtcagagaggatgctggtacttacatgtgtgtggct cagaatccagctggtacagccttgggcaaaatcaagttgaatgtccaagttcctccagtc attacccctcatccaaaggaatacgtcactgttgtggataagcccatcatgctaccctgt gaggcagatggcctcccaccacctgacatcatgtggcataaagatgggcatgtaattatg gagtcagtccgccagcgcatcctcagctccggtgctctgcagatagcatttgctcagcct ggtgatgctggccagtacacgtgcatggcagctaacgtggcaggatcaagcagcacgagc accaagctcaccgtgcatgtaccacctagaatccaaagtacagaagtacattacacggtc aatgagaattcacaagccgttcttccatgtgtggctgatggaatccccacaccagcaatt aactggaaaaaagacaatgttcttttggctaacttgttaggaaaatatactgtcgaaccc tatggagagcttctcctggaaaatgttgtgccggaggattctggcacctatacctgcatt gctaacaatgccgcaggtgaagacacacacaccatcagcctgactgttcatgttcttccc acttttactgaactccctggagatgtgtcattaaataagggagaacagctccgattaaac tgtaaagcaactggtattccattgcccaagttaacatggaccttcaataacaatatcatc ccagcccactttgacagcgtcagtggacacagtgaacttgttattgaaaggatatcaaaa gaggattcaggcacttacgtgtgcactgccgaaaacagcgttggttttgtgaaggcaatt ggatttgtttatgtgaaagaacctccagtcttcaaaggtgattacccttctaactggatt gaaccacttggtggtaatgcaatcctgaattgtgaggtgaaaggagatcccgccccaacc atccagtggagcagaagggggattgatattgaaattagccacagaatccggcaacttggc aatggctccttggccatttatggcactgtgaatgaagatgctggtgattatacatgtgta gctaccaatgaagctggggtggtggaacgcagcatgagtctgactttgcaaagtcctcct attatcactcttgaaccagtagaaactattattaatgctggcagcaaagtcatcttgaat tgtcaagcaactggagagcctcgtccaaccattacatggtcccgtcaagggcactctatc ctctgggatgagcgaattaatgtgttgtccaacaactcattacatatcgctgctgctcag aaagaagatacatctgagtatgaatgcgttgctcgaaacttgatgggttctgtccttgtg agagtgcctgtcatagtccaggtccccggtggcttttcccagtggtcggcctggagaccc tgcagtgtcacctgtggaaaagggatccagaagaggagtcgtctgtgcaacaacccctct ccagccaacggggggaagccttgccagggatcggattcagaaatacaaaactgtcaccat aagccgtgtccagtggatgggaactggtcagaatggagtctctgggaagaatgcacgagg agctgtggacgcggcaaccgaaccaggaccagaacttgcaataatccatcagctcaacac ggtgggcggccgtgtgacgggattgccgtggaaaccatcatgtgcaacattcggccttgc ccagttcacggagcatggagtacctggcagccttgggggacatgcagcgtaagttgtgga aaaggtacccaaacaagaacaagactgtgcaataacccaccaccatcatttgctggatcc tactgtgatggagcagaaacacagatgcaagtttgcaatgaaagacactgcccaatcgat ggcaagtgggccacttggaccagttggagtgcctgttctgtatcctgtggaggtggcgcc aggcagagaacaagggactgctctgatcctgctccccagtatggaggcaacaaatgtgaa gggagtgatgtccagagtgatttttgtaatagtgactcttgtccaactcatggtaactgg agtccttggagtggctggggaatatgcagccggacatgtaatggggggcagatgcggcgg taccgcacatgtgataaccctcatccctccaatggaggaagagcttgtgggggcccagac tcccagatccagagatgcaacacggacatgtgtcctgtggatggaagttggggaaactgg catagttggagctggtgttccacctcttgtggaggaggtgaaaagacacgaaaacggctg tgcaacaatccaataccatctaaaagtggtcgcccctgcccaggcgatgctactcaggta tccagatgtaatatacaagtatgtccaggtgggccccagcgagccagaggaagtgttatt ggaagcattaatgatgttgaatttggaatcgctttccttaacgccacggtcacagatagc ccaaactctgatactagaataatacatgccaaaattaccaatgtacctcgcagtcttggt ccagcaatgagaaagatagtttctattctaaatcccatttattggacaacagcaaaagaa ataggagaagcagtcaatggctttaccctcaccaatgcagttttcaagagagaaacccaa gtggaatttgcaactggagaaatcttgcggatgactcacgttgcccggggcttggattct gatggtgctctactggtagatatcattgtgagtggccacgtcctgcagctacagtcacct gccgaagtcactgtgaaggattacactgaggactacgttcaaacaggtgctgggcagctg tatgcctactcaacccggctgttcaccattgatggcatcagcgtcccttacacatggaac cacactgtcttctatgatgaggcacagggaagaatgccttttttggtagaaacacttcat gcatcctctgtggaatctgactacaaccagctagaagagacactgggttttaaaatccat gctgcaatttccaaaggagaacgcagtaatcagtgtccctctgggtttgccttagactcg gtcggacccttttgtgctgatgaagatgaatgtgccacagggaatccctgctctcatttc tgtcacaatgccatgggaacctattattgctcctgccccaaaggcctcaccatagctgcc gatggaagaacctgtcaagatattgatgagtgtgctttgggtggatacacctgccatgct ggtcaggactgtgataataccatcggatcctatcgctgtgtagtccgctgtggaattggc tttcgaagaaccagtgatgggctgagttgtcaagatattaatgaatgtcaagaatccagc ccctgtcaccaccgctgtttcaatgccataggaagttttcactgtggatgtgaacctggg tatcagctcaaaggcagaaaatgtgtggatataaatgagtgtagacagaatgtatgcaga ccagatcagcactgcaagaacactcgcggtggctataaatgcattgatctctgtccaaat ggaatgaccaaggcagaaaacggaacctgcattgatgttgatgagtgtaaagatgggacc catcagtgcagatataaccagatatgtgagaatacaagaggcagctatcgttgtgtgtgt ccaagagggtaccggtctcaaggacttggaagaccctgtttggatattaatgaatgtgaa caagtgtctaagccttgtgcatatcagtgcttcaacacccctggcagcttcaagtgtatc tgtccaccaggacaacatttgttaggggacgggaaatcttgcgctggactggagaggctg ccaaattatggcactcaatacaatagctataaccttgcacgcttctcccccatgagaaac aactatcaacctcaacagcattacagacagtactcacatctctacagctcctactcagag tataggaacagcagaacatctctctccaggactagaaggactattaggaaaacttgcccc gaaggctctgaggcgagccttgacacatgtgtagatattaatgaatgtgaaaatactgac acctgccagcatgagtgtaaaaatacctttgggagctatcggtgtatctgtccacctggc tatcagctcatgatcaatggaaagacatgtcaagatattgatgagtgcctggaacagaat gtgcgctgtgggccaaatcgcatgtgcttcaacatgagaggaagctaccgctgcattgag acaccctgtccacctgactaccaacgggatcctgtgtcagggttctgtctcaagaactgt ccacccaatgatttggaatgtgccttgagtccatatgccctggaatacaaactcgtctcc ctcccgtttggaatagctgccaatcaagatttgatccggctggttgcatacacgcaagat ggagtgatgcatcccaggacaactttcctcatgatagatgaggaacagaccattcccttt gccttaagggatgaaaacctgaaaggagtggtgtacacaatacgaccactgcaagaacca gagacctaccgcatgagggttcgagccttatcctacagtgccaacgggaccgttgagtat cagaccacattcattgtttatatagctgtgtctgcctatccatactaa

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