Ovis canadensis (bighorn sheep): 138427786
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Entry
138427786 CDS
T11679
Symbol
FGFR2
Name
(RefSeq) fibroblast growth factor receptor 2 isoform X1
KO
K05093
fibroblast growth factor receptor 2 [EC:
2.7.10.1
]
Organism
ocan Ovis canadensis (bighorn sheep)
Pathway
ocan01521
EGFR tyrosine kinase inhibitor resistance
ocan04010
MAPK signaling pathway
ocan04014
Ras signaling pathway
ocan04015
Rap1 signaling pathway
ocan04020
Calcium signaling pathway
ocan04144
Endocytosis
ocan04151
PI3K-Akt signaling pathway
ocan04550
Signaling pathways regulating pluripotency of stem cells
ocan04810
Regulation of actin cytoskeleton
ocan05200
Pathways in cancer
ocan05215
Prostate cancer
ocan05226
Gastric cancer
ocan05230
Central carbon metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
ocan00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
138427786 (FGFR2)
04014 Ras signaling pathway
138427786 (FGFR2)
04015 Rap1 signaling pathway
138427786 (FGFR2)
04020 Calcium signaling pathway
138427786 (FGFR2)
04151 PI3K-Akt signaling pathway
138427786 (FGFR2)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
138427786 (FGFR2)
09144 Cellular community - eukaryotes
04550 Signaling pathways regulating pluripotency of stem cells
138427786 (FGFR2)
09142 Cell motility
04810 Regulation of actin cytoskeleton
138427786 (FGFR2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
138427786 (FGFR2)
05230 Central carbon metabolism in cancer
138427786 (FGFR2)
09162 Cancer: specific types
05226 Gastric cancer
138427786 (FGFR2)
05215 Prostate cancer
138427786 (FGFR2)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
138427786 (FGFR2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
ocan01001
]
138427786 (FGFR2)
09183 Protein families: signaling and cellular processes
04090 CD molecules [BR:
ocan04090
]
138427786 (FGFR2)
00536 Glycosaminoglycan binding proteins [BR:
ocan00536
]
138427786 (FGFR2)
Enzymes [BR:
ocan01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
138427786 (FGFR2)
Protein kinases [BR:
ocan01001
]
Receptor tyrosine kinases (RTK)
FGFR family [OT]
138427786 (FGFR2)
CD molecules [BR:
ocan04090
]
Proteins
138427786 (FGFR2)
Glycosaminoglycan binding proteins [BR:
ocan00536
]
Heparan sulfate / Heparin
Growth factors/receptors
138427786 (FGFR2)
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
I-set
Ig_3
ig
Ig_2
V-set
Ig_5
ABC1
C2-set_2
V-set_CD47
Kinase-like
Pkinase_fungal
Motif
Other DBs
NCBI-GeneID:
138427786
NCBI-ProteinID:
XP_069423830
LinkDB
All DBs
Position
22:complement(56705956..56809981)
Genome browser
AA seq
841 aa
AA seq
DB search
MGLTSTWRYGRGQGIGTVTMVSWGRFLCLVVVTMATLSLARPSFNLVDDTTVEPEEPPTK
YQISQPEVYVAAPRESLELRCLLRDAAMISWTKDGVHLGPNNRTVLIGEYLQIKGATPRD
SGLYACTAARNVDSETVYFMVNVTDAISSGDDEDDADGSEDFVSENSNSKRAPYWTNTEK
MEKRLHAVPAANTVKFRCPAGGNPTPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESV
VPSDKGNYTCVVENDYGSINHTYHLDVVERSPHRPILQAGLPANASTVVGGDVEFVCKVY
SDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKHSGINSSNAEVLALFNVTEADAGEYICK
VSNYIGQANQSAWLTVLPKQQAPVREKEIPASPDYLEIAIYCIGVFFIACMVVTVILCRM
RNTTKKPDFSSQPAVHKLTKRIPLRRQVTVSAESSSSMNSNTPLVRITTRLSSTADTPML
AGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKEKPKEAVTVAVKMLK
DDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARR
PPGMEYSYDINRVPEEQMAFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVM
KIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLG
GSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRI
LTLTTNEEYLDLSQLLEQYSPSYPDTRSSCSSGDDSVFSPDPMPYEPCLPQYPHRNGSVK
T
NT seq
2526 nt
NT seq
+upstream
nt +downstream
nt
atgggattaacgtccacatggagatatggaagaggacaggggatcggcactgtaaccatg
gtcagctggggtcgcttcctctgcctggttgtggtcaccatggcaaccttgtccctggcc
cggccctccttcaatttagttgacgataccacggttgagccggaagagccaccaaccaaa
taccaaatctcccaaccagaagtttacgtggctgcgccccgggagtcgctagagttgcgc
tgcctgttgcgagatgccgccatgatcagttggactaaggatggggtacacttggggccc
aacaataggacagtgcttattggggagtatttgcagataaaaggtgccacgcctagagac
tccggcctctatgcttgtactgctgctaggaacgtagacagtgagactgtctacttcatg
gtcaatgttacagatgccatctcatccggagatgatgaggacgacgcagatggctcggag
gattttgtcagtgagaacagtaacagcaagagagcaccgtactggaccaacacagaaaag
atggaaaaacggctgcacgcggtcccagcagccaacactgtcaagttccgctgcccagct
ggggggaatccaacaccaaccatgaggtggctgaaaaacgggaaggaatttaagcaggag
catcgcattggaggctataaggtacgaaaccagcattggagccttattatggaaagtgtg
gtcccgtctgacaaaggaaattatacctgcgtggtggagaacgattacgggtccatcaat
catacgtaccacctcgacgttgttgagcgatcaccacaccggcccatcctccaagctggg
ctgccagcaaatgcctccactgtggttggaggcgatgtggagtttgtctgcaaagtgtac
agcgatgcccagccccatatccagtggatcaaacatgtggaaaagaacggcagtaaatac
gggcccgacgggctgccctatctcaaggttctgaagcactcggggataaatagttccaat
gcagaagtgctggctctgttcaatgtgactgaggcggatgctggggagtatatttgtaag
gtctccaattatatagggcaggccaaccagtctgcctggctcactgtcctgccaaaacag
caagctcctgtaagagaaaaggagatcccagcttccccagactacctggaaatagccatt
tactgcataggggtgttcttcatcgcctgcatggtggtgacagtcatcttgtgccggatg
aggaacacgaccaagaagccggacttcagcagccagccggctgtgcacaagctgaccaag
cgtatccccctgcggagacaggtaacagtttctgctgagtccagctcctctatgaactcc
aacaccccgttggtgaggattacaactcgtctctcttcaacggcagacacccccatgctg
gcaggggtctccgagtatgagctgccagaagatcccaaatgggagtttccaagagataag
ctgacgctgggcaaacccctgggagaaggttgctttgggcaagtggtcatggctgaagca
gtgggaattgacaaggagaagcccaaggaagcagtcactgtggccgtgaagatgttgaaa
gatgatgccactgagaaagacctttctgatctggtgtctgagatggagatgatgaagatg
attgggaaacacaaaaatatcataaatctccttggagcctgtactcaggatgggccgctc
tatgtcatcgtcgagtacgcctcaaaaggcaatcttcgggaatacctccgcgcccggagg
ccacccgggatggagtattcctatgacatcaaccgcgttcccgaggagcagatggccttc
aaggacttggtgtcgtgcacctaccagctggcccggggcatggagtacttggcttcccag
aaatgcattcatcgagatttagctgccagaaatgttttggtaacagaaaacaacgtgatg
aaaatagctgactttggactggccagagatatcaacaatatagactattacaaaaagacc
acaaatggccgacttccggtcaagtggatggctcctgaagcccttttcgacagagtgtac
acccatcagagtgatgtctggtccttcggggtgttaatgtgggagatcttcacgttaggg
ggctcgccctacccagggattcccgtggaggaactttttaagctgcttaaggaaggacat
aggatggacaagccagcaaactgcaccaacgaactgtatatgatgatgagagactgctgg
catgcagtaccctcacagagacccaccttcaagcagttggtagaagacttggatcgaatt
ctcacactcacaaccaacgaggaatacttggacctcagtcagcttcttgaacagtattca
cctagttaccctgacaccaggagttcttgctcttcgggagatgattctgttttctctccg
gaccccatgccttacgaaccctgccttcctcagtatccacatagaaacggcagtgttaaa
acatga
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